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Prevalence and Predictors of Hypovitaminosis D Among Female University Students in Tabuk, Saudi Arabia. 沙特阿拉伯塔布克女大学生维生素 D 不足的患病率和预测因素。
Pub Date : 2017-04-06 eCollection Date: 2017-01-01 DOI: 10.1177/1179562X17702391
Riyadh A Alzaheb, Osama Al-Amer

Background: A high hypovitaminosis D prevalence has repeatedly been reported in Middle Eastern countries. Previous data regarding the vitamin D status of young women in Saudi Arabia and the related hypovitaminosis D risk factors are scarce, so this research assessed hypovitaminosis D prevalence and its risk factors among apparently healthy female university students in Tabuk, Saudi Arabia.

Methods: This cross-sectional research used a convenience sample of healthy female students (n = 180) aged between 19 and 25 years in May 2016. Information was gathered on the participants' sociodemographics, health, lifestyle, dietary intakes, anthropometry, and serum 25-hydroxyvitamin D (25(OH)D), and a logistic regression analysis was performed to assess hypovitaminosis D risk factors.

Results: The sample's hypovitaminosis D prevalence (25(OH)D <30 ng/mL) was 80.6%. The main determinants of hypovitaminosis D were as follows: urban residence (odds ratio [OR] = 6.54; 95% confidence interval [CI], 2.74-5.63), rare sun exposure (OR = 6.14; 95% CI, 2.15-17.55), and insufficient vitamin D intake (OR = 2.50; 95% CI, 1.07-5.81).

Conclusions: The findings emphasize that despite plentiful sunshine, Saudi Arabia and the Middle East face a vitamin D deficiency epidemic. Vitamin D status must therefore be assessed at the national level so that strategies aimed at boosting vitamin D levels can be instigated.

背景:在中东国家,维生素 D 缺乏症的发病率一直很高。此前有关沙特阿拉伯年轻女性维生素 D 状态及相关维生素 D 缺乏症风险因素的数据很少,因此本研究评估了沙特阿拉伯塔布克表面健康的女大学生中维生素 D 缺乏症的患病率及其风险因素:这项横断面研究于 2016 年 5 月对年龄在 19 至 25 岁之间的健康女大学生(n = 180)进行了方便抽样调查。收集了参与者的社会人口统计学、健康状况、生活方式、饮食摄入量、人体测量和血清 25- 羟基维生素 D(25(OH)D)等信息,并进行了逻辑回归分析,以评估维生素 D 缺乏症的风险因素:结果:样本的维生素 D 缺乏症患病率(25(OH)D研究结果强调,尽管沙特阿拉伯和中东地区日照充足,但仍面临维生素 D 缺乏症的流行。因此,必须在全国范围内对维生素 D 状态进行评估,以便制定旨在提高维生素 D 水平的战略。
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引用次数: 0
Adaptation of Maternal-Fetal Physiology to Exercise in Pregnancy: The Basis of Guidelines for Physical Activity in Pregnancy. 妊娠期母胎生理对运动的适应:妊娠期体力活动指南的基础。
Pub Date : 2017-02-23 eCollection Date: 2017-01-01 DOI: 10.1177/1179562X17693224
Edward R Newton, Linda May

Only 50 years ago obstetric care providers and women had many concerns regarding whether exercise during pregnancy created a harmful competition for substrate resources between the fetus and the mother. Animal and human research in the past 50 years, which includes acute and chronic aerobic exercise during pregnancy, has a reassuring margin of safety throughout gestation in women. Maternal physiology adapts to pregnancy changes involving the cardiorespiratory and glucometabolic alterations. Due to these changes, pregnant women have slight differences in response to acute exercise sessions. Chronic exposure to aerobic exercise before and during pregnancy is associated with numerous maternal and neonatal adaptations which may have short- and long-term benefits to maternal and child health. On the basis of the consistent evidence of safety of exercise during pregnancy, multiple nations and health care organizations, including the American College of Obstetrics and Gynecology, recommend moderate exercise for 20 to 30 minutes most days of the week. Despite the 15 to 20 years since the first recommendations were made, only 10% to 15% of pregnant women meet this recommendation. It seems there may be 2 foci for failure to achieve these exercise recommendations: patient specific and culturally driven and/or obstetric provider not recommending regular exercise due to lack of knowledge or motivation. This article addresses the provider knowledge by a review of the normal (at rest) physiologic adaptation to pregnancy. Then, we provide a detailed description of the type and intensity of controlled experiments that document the safety of exercise during pregnancy. The short- and long-term benefits are reviewed, including the safety in moderate-risk women.

仅仅在50年前,产科护理提供者和妇女们对怀孕期间的运动是否会造成胎儿和母亲之间对基础资源的有害竞争感到担忧。在过去50年的动物和人类研究中,包括怀孕期间的急性和慢性有氧运动,有一个令人放心的安全边际,妇女在整个怀孕期间。母体生理适应妊娠变化,包括心肺和糖代谢的改变。由于这些变化,孕妇对急性运动的反应略有不同。在怀孕前和怀孕期间长期暴露于有氧运动与许多孕产妇和新生儿适应有关,这可能对孕产妇和儿童健康有短期和长期的好处。基于怀孕期间运动安全的一致证据,包括美国妇产科学院在内的多个国家和卫生保健组织建议一周中大部分时间进行20至30分钟的适度运动。尽管自第一次建议提出以来已有15至20年,但只有10%至15%的孕妇符合这一建议。未能实现这些运动建议可能有两个焦点:患者特定和文化驱动和/或产科医生不建议定期运动,由于缺乏知识或动力。本文通过对正常(静止)妊娠生理适应的回顾来解决提供者的知识。然后,我们提供了一个详细描述的类型和强度的对照实验,记录在怀孕期间运动的安全性。评估了短期和长期的益处,包括对中度风险妇女的安全性。
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引用次数: 38
Progesterone for Luteal Phase Support in In Vitro Fertilization: Comparison of Vaginal and Rectal Pessaries to Vaginal Capsules: A Randomized Controlled Study 黄体酮在体外受精中的黄体期支持:阴道和直肠子宫托与阴道胶囊的比较:一项随机对照研究
Pub Date : 2017-01-05 DOI: 10.4137/CMWH.S32156
M. Khrouf, Soufiene Slimani, M. Khrouf, Marouen Braham, M. Bouyahia, K. Berjeb, Hanène Chaabane, G. Merdassi, A. Kaffel, A. Zhioua, F. Zhioua
BACKGROUND In IVF, Luteal phase support is usually performed using vaginal progesterone. A part of patients using this route reports being uncomfortable with this route. We tried to study whether the rectal route could be an effective alternative and associated with less discomfort. PATIENTS AND METHODS A prospective randomized controlled study. All patient were eligible for IVF treatment for infertility. After oocyte pickup, 186 patients were allocated to one the following protocols for luteal phase support: (i) rectal pessaries group: natural progesterone pessaries administered rectally 200 mg three times a day, (ii) vaginal pessaries group: natural progesterone pessaries administered vaginally 200 mg three times a day), and (iii) vaginal capsules group: natural micronized progesterone capsules administered vaginally 200 mg three times a day. On the day of pregnancy test, patients were asked to fill in a questionnaire conducted by an investigator in order to assess the tolerability and side effects of the LPS treatment taken. The primary endpoint was the occurrence of perineal irritation. RESULTS Fifty eight patients were assigned to the rectal pessaries group, 68 patients to the vaginal pessaries group, and 60 patients to the vaginal capsules group. All patients adhered to their allocated treatment. Implantation and clinical pregnancy rates per transfer did not differ between the three groups. Perineal irritation, which was our primary endpoint, was the same for all the three groups (respectively 1.7 % versus 5.9 % versus 11.7%). Regarding the other side effects, more patients experienced constipation and flatulence with the rectal route, whereas more patients reported vaginal discharge in the vaginal capsules group. CONCLUSION Rectal administration for luteal phase support is effective and well accepted alternative to vaginal route.
背景:在体外受精中,黄体期支持通常使用阴道黄体酮。使用这种方法的一部分患者报告说,这种方法不舒服。我们试图研究直肠途径是否可以成为一种有效的替代方法,并减少不适。患者和方法一项前瞻性随机对照研究。所有患者均符合体外受精治疗不孕症的条件。提取卵母细胞后,186名患者被分配到以下黄体期支持方案之一:(i)直肠子宫托组:每天三次直肠给予天然孕酮子宫托200毫克,(ii)阴道子宫托组:每天三次阴道给予天然孕酮子宫托200毫克,(iii)阴道胶囊组:每天三次阴道给予天然微化孕酮胶囊200毫克。在妊娠试验当天,患者被要求填写一份调查问卷,以评估所采取的LPS治疗的耐受性和副作用。主要终点是会阴刺激的发生。结果直肠子宫托组58例,阴道子宫托组68例,阴道胶囊组60例。所有的病人都坚持接受分配的治疗。每次移植的植入率和临床妊娠率在三组之间没有差异。会阴刺激,这是我们的主要终点,在所有三组中是相同的(分别为1.7%、5.9%和11.7%)。至于其他副作用,更多的患者在直肠途径出现便秘和胀气,而阴道胶囊组更多的患者报告阴道分泌物。结论直肠给药对黄体期的支持是阴道途径的有效替代。
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引用次数: 10
Ethnic Identity Attachment and Motivation for Weight Loss and Exercise Among Rural, Overweight, African-American Women 农村、超重、非裔美国妇女的种族认同、依恋和减肥和锻炼动机
Pub Date : 2016-11-17 DOI: 10.4137/CMWH.S34691
K. Smalley, J. Warren, Sydney McClendon, W. Peacock, M. Caro
Rural and minority women are disproportionately impacted by the obesity epidemic; however, little research has studied the intersection of these disparity groups. The purpose of this study was to examine the influence of racial identity on motivation for weight loss and exercise among rural, African-American women with an obesity-linked chronic disease. A total of 154 African-American women were recruited from the patient population of a Federally Qualified Health Center in the rural South to complete a questionnaire battery including the Multigroup Ethnic Identity Measure and separate assessments of motivation for weight loss and exercise. Multivariate analyses, controlling for age, education status, insurance status, and body mass index revealed that attachment to ethnic identity was predictive of motivation for exercise but not for weight loss. Our findings suggest that attachment to ethnic identity may be an important factor in motivation for change among African-American women, particularly with respect to exercise, with direct implications for the development of culturally and geographically tailored weight loss interventions.
农村妇女和少数民族妇女不成比例地受到肥胖流行病的影响;然而,很少有研究研究这些差异群体的交集。本研究的目的是研究种族认同对患有肥胖相关慢性疾病的非洲裔农村妇女减肥和锻炼动机的影响。研究人员从南部农村一家联邦合格医疗中心的患者中招募了154名非裔美国妇女,让她们完成一系列问卷调查,其中包括多群体种族认同测量和对减肥和锻炼动机的单独评估。控制年龄、教育状况、保险状况和体重指数的多变量分析显示,对种族身份的依恋可以预测锻炼的动机,但不能预测减肥的动机。我们的研究结果表明,对种族身份的依恋可能是非裔美国女性改变动机的一个重要因素,特别是在锻炼方面,这直接影响了文化和地理上量身定制的减肥干预措施的发展。
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引用次数: 9
Identifying Contextual and Emotional Factors to Explore Weight Disparities between Obese Black and White Women 识别环境和情感因素探讨肥胖黑人和白人妇女之间的体重差异
Pub Date : 2016-10-31 DOI: 10.4137/CMWH.S34687
N. Keith, Huiping Xu, M. de Groot, Kimberly Hemmerlein, D. Clark
BACKGROUND Obese black women enrolled in weight loss interventions experience 50% less weight reduction than obese white women. This suggests that current weight loss strategies may increase health disparities. OBJECTIVE We evaluated the feasibility of identifying daily contextual factors that may influence obesity. METHODS In-home interviews with 16 obese (body mass index ≥ 30) black and white urban poor women were performed. For 14 days, ecological momentary assessment (EMA) was used to capture emotion and social interactions every other day, and day reconstruction method surveys were used the following day to reconstruct the context of the prior day’s EMA. RESULTS Factors included percentage of participants without weight scales (43.8%) or fitness equipment (68.8%) in the home and exposed to food at work (55.6%). The most frequently reported location, activity, and emotion were home (19.4 ± 8.53), working (7.1 ± 8.80), and happy (6.9 ± 10.03), respectively. CONCLUSION Identifying individual contexts may lead to valuable insights about obesogenic behaviors and new interventions to improve weight management.
背景:参加减肥干预的肥胖黑人妇女比肥胖白人妇女减重少50%。这表明目前的减肥策略可能会增加健康差距。目的:我们评估确定可能影响肥胖的日常环境因素的可行性。方法对16名肥胖(体重指数≥30)黑人和白人城市贫困妇女进行家庭访谈。在14天内,每隔一天使用生态瞬时评估(EMA)来捕捉情感和社会互动,第二天使用日重建法调查来重建前一天EMA的背景。影响因素包括家中没有体重秤(43.8%)或健身器材(68.8%)以及在工作中接触食物(55.6%)的参与者比例。最常报告的地点、活动和情绪分别是家(19.4±8.53)、工作(7.1±8.80)和快乐(6.9±10.03)。结论识别个体环境可能有助于了解致肥行为和改善体重管理的新干预措施。
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引用次数: 2
The Influence of Prenatal Exercise on Offspring Health: A Review 产前运动对子代健康的影响
Pub Date : 2016-10-17 DOI: 10.4137/CMWH.S34670
C. Moyer, O. R. Reoyo, L. May
Research has continued to demonstrate that exercise during pregnancy is safe. Growing evidence supports that exercise during pregnancy is beneficial for mother and fetus during gestation, with benefits persisting for the child into adulthood. Regardless of income or socioeconomic status, exercise during pregnancy is associated with increased incidence of full-term delivery. Additionally, normalization of birth measures, such as birth weight, occurs when women perform regular exercise throughout gestation. Measures of growth and development further indicate that exercise during pregnancy does not harm and may stimulate healthy growth throughout childhood. Measures of cognition and intelligence demonstrate that exercise during pregnancy causes no harm and may be beneficial. Overall, the benefits of exercise during pregnancy decrease the risk of chronic disease for both mother and child.
研究表明,怀孕期间的运动是安全的。越来越多的证据表明,怀孕期间的锻炼对母亲和胎儿都有好处,这种好处会持续到孩子成年。无论收入或社会经济地位如何,怀孕期间的锻炼与足月分娩的发生率增加有关。此外,分娩措施的正常化,如出生体重,发生在妇女在整个怀孕期间进行定期运动。对生长和发育的测量进一步表明,怀孕期间的运动没有危害,而且可能促进整个儿童时期的健康成长。对认知和智力的测量表明,怀孕期间的锻炼不会造成伤害,反而可能有益。总的来说,怀孕期间锻炼的好处可以降低母亲和孩子患慢性病的风险。
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引用次数: 48
Effects of a 12-Month Pedometer-Based Walking Intervention in Women of Low Socioeconomic Status 基于计步器的12个月步行干预对低社会经济地位妇女的影响
Pub Date : 2016-10-06 DOI: 10.4137/CMWH.S39636
Lyndsey M. Hornbuckle, J. Kingsley, M. Kushnick, R. Moffatt, E. Haymes, R. Miles, T. Toole, L. Panton
This study examined the effects of a 12-month walking intervention in overweight/obese, low socioeconomic women. Forty-six women (48.2 ± 8.0 years) entered the study. Outcomes included weight, waist and hip circumferences, body mass index (BMI), blood pressure, glycosylated hemoglobin, blood lipids, fibrinogen, and high-sensitivity C-reactive protein (hsCRP). Both intention-to-treat analyses in all participants and group analyses in study completers only (3K group = increased steps/day by ≥3,000; No Δ group = did not increase steps/day by ≥3,000) were conducted. Group × time ANOVA was used. In study completers, 3K significantly increased steps/day (6,903 ± 3,328 to 12,323 ± 5,736) compared to No Δ (4,926 ± 3,374 to 5,174 ± 3,095) from baseline to 12 months. There was a significant time effect for weight (P = 0.030), BMI (P = 0.029), and hsCRP (P = 0.044). Low socioeconomic women who adhere to a long-term, pedometer-based walking intervention significantly increased steps/day and may improve body weight, BMI, and hsCRP. This could help reduce health disparities in this population over time.
这项研究对超重/肥胖、社会经济地位低的女性进行了为期12个月的步行干预。46名女性(48.2±8.0岁)进入研究。结果包括体重、腰围和臀围、体重指数(BMI)、血压、糖化血红蛋白、血脂、纤维蛋白原和高敏c反应蛋白(hsCRP)。所有参与者的意向治疗分析和仅研究完成者的组分析(3K组=每天增加步数≥3000;没有Δ组=没有增加≥3000步/天)。采用组×时间方差分析。在研究完成者中,从基线到12个月,与No Δ(4,926±3,374至5,174±3,095)相比,3K组显著增加了每天的步数(6,903±3,328至12,323±5,736)。体重(P = 0.030)、BMI (P = 0.029)和hsCRP (P = 0.044)存在显著的时间效应。长期坚持以计步器为基础的步行干预的低社会经济地位妇女显著增加了每天的步数,并可能改善体重、BMI和hsCRP。随着时间的推移,这可能有助于减少这一人群的健康差距。
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引用次数: 14
Correction to “Barriers to Obtaining Sera and Tissue Specimens of African-American Women for the Advancement of Cancer Research” 对“获取非裔美国妇女血清和组织标本以促进癌症研究的障碍”的更正
Pub Date : 2016-09-13 DOI: 10.4137/CMWH.S40655
K. Strissel, Dequina A Nicholas, M. Castagne-Charlotin, N. Ko, G. Denis
[This corrects the article DOI: 10.4137/CMWH.S34698.].
[更正文章DOI: 10.4137/CMWH.S34698.]。
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引用次数: 0
Patient Navigators: Agents of Creating Community-Nested Patient-Centered Medical Homes for Cancer Care. 患者导航员:为癌症护理创建社区嵌套的以患者为中心的医疗之家的代理人。
Pub Date : 2016-08-25 eCollection Date: 2016-01-01 DOI: 10.4137/CMWH.S39136
Melissa A Simon, Athena T Samaras, Narissa J Nonzee, Nadia Hajjar, Carmi Frankovich, Charito Bularzik, Kara Murphy, Richard Endress, Laura S Tom, XinQi Dong
Patient navigation is an internationally utilized, culturally grounded, and multifaceted strategy to optimize patients’ interface with the health-care team and system. The DuPage County Patient Navigation Collaborative (DPNC) is a campus–community partnership designed to improve access to care among uninsured breast and cervical cancer patients in DuPage County, IL. Importantly, the DPNC connects community-based social service delivery with the patient-centered medical home to achieve a community-nested patient-centered medical home model for cancer care. While the patient navigator experience has been qualitatively documented, the literature pertaining to patient navigation has largely focused on efficacy outcomes and program cost effectiveness. Here, we uniquely highlight stories of women enrolled in the DPNC, told from the perspective of patient navigators, to shed light on the myriad barriers that DPNC patients faced and document the strategies DPNC patient navigators implemented.
患者导航是一种国际通用的、基于文化的、多方面的策略,用于优化患者与医疗团队和系统的界面。杜佩奇县患者导航协作(DPNC)是一个校园-社区合作项目,旨在改善伊利诺伊州杜佩奇县未投保的乳腺癌和宫颈癌患者获得护理的机会。重要的是,DPNC将社区为基础的社会服务提供与以患者为中心的医疗之家联系起来,实现以社区为中心的癌症护理医疗之家模式。虽然患者导航经验已被定性记录,但有关患者导航的文献主要集中在疗效结果和项目成本效益上。在这里,我们从患者导航员的角度讲述了参加DPNC的女性的故事,以阐明DPNC患者面临的无数障碍,并记录了DPNC患者导航员实施的策略。
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引用次数: 5
A Public Health Priority: Disparities in Gynecologic Cancer Research for African-Born Women in the United States. 公共卫生优先事项:美国非洲裔妇女妇科癌症研究的差异
Pub Date : 2016-07-27 eCollection Date: 2016-01-01 DOI: 10.4137/CMWH.S39867
Leeya F Pinder, Brett D Nelson, Melody Eckardt, Annekathryn Goodman

African-born immigrants comprise one of the fastest growing populations in the U.S., nearly doubling its population size in recent years. However, it is also one of the most underrepresented groups in health-care research, especially research focused on gynecologic and breast malignancies. While the opportunity exists for access to an advanced health-care system, as immigrants migrate to the U.S., they encounter the same health-care inequalities that are faced by the native-born population based on ethnicity and social class, potentiated by limitations of health literacy and lack of familiarity with U.S. health systems. Given the continued influx of African-born immigrants in the U.S., we sought to understand the representation of this population in cervical and breast cancer research, recognizing the population's high risk for these diseases at baseline while residing in their native countries. We determined that there is limited research in these diseases that disproportionately affect them; yet, there are identifiable and potentially modifiable factors that contribute to this paucity of evidence. This clinical commentary seeks to underscore the clear lack of research available involving African-born immigrants with respect to gynecologic and breast malignancies in the existing literature, demonstrate the need for more robust research in this population, and provide fundamental insights into barriers and solutions critical to the continued health of this growing population.

非洲出生的移民是美国增长最快的人口之一,近年来其人口规模几乎翻了一番。然而,它也是保健研究中代表性最不足的群体之一,特别是以妇科和乳腺恶性肿瘤为重点的研究。虽然有机会获得先进的医疗保健系统,但随着移民移民到美国,他们面临着与本土出生人口相同的基于种族和社会阶层的医疗保健不平等,卫生知识的限制和对美国卫生系统的不熟悉加剧了这种不平等。鉴于美国不断涌入非洲出生的移民,我们试图了解这一人群在宫颈癌和乳腺癌研究中的代表性,认识到这些人群在居住在原籍国时患这些疾病的基线风险很高。我们确定,对这些不成比例影响他们的疾病的研究有限;然而,有一些可识别的和潜在的可修改的因素导致了证据的缺乏。这篇临床评论试图强调现有文献中明显缺乏涉及非洲出生移民的妇科和乳腺恶性肿瘤的研究,证明需要对这一人群进行更有力的研究,并提供对这一不断增长的人口的持续健康至关重要的障碍和解决方案的基本见解。
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引用次数: 10
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Clinical medicine insights. Women's health
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