Avani Singh, Michael Kuncewitch, P. Mansoori, James T. Mothershed, E. Levine
Digital Papillary Adenocarcinoma (DPA) is a very rare neoplasm of sweat glands, with approximately 100 cases in the literature. We present a rare case of DPA of the ankle in a 66-year-old African American man. DPA has a high potential for metastases to the lung and lymph nodes, and initial treatment often entails wide excision or complete digital amputation. DPA typically presents as a painless lesion or mass of the distal digits of the hands or feet. With the limited available literature regarding this malignancy, there is no standard approach to treatment. Wide excisional margins with sentinel lymph node mapping and biopsy are based on extrapolation for other tumors. In the following report, we discuss a representative case and the current literature on the presentation, treatment and pathology of this rare neoplasm.
{"title":"Digital papillary adenocarcinoma of the ankle","authors":"Avani Singh, Michael Kuncewitch, P. Mansoori, James T. Mothershed, E. Levine","doi":"10.5430/CRCP.V4N3P24","DOIUrl":"https://doi.org/10.5430/CRCP.V4N3P24","url":null,"abstract":"Digital Papillary Adenocarcinoma (DPA) is a very rare neoplasm of sweat glands, with approximately 100 cases in the literature. We present a rare case of DPA of the ankle in a 66-year-old African American man. DPA has a high potential for metastases to the lung and lymph nodes, and initial treatment often entails wide excision or complete digital amputation. DPA typically presents as a painless lesion or mass of the distal digits of the hands or feet. With the limited available literature regarding this malignancy, there is no standard approach to treatment. Wide excisional margins with sentinel lymph node mapping and biopsy are based on extrapolation for other tumors. In the following report, we discuss a representative case and the current literature on the presentation, treatment and pathology of this rare neoplasm.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":" ","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2017-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N3P24","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44701909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A solitary cystic lesion in the abdominal wall is generally benign, such as an omental cyst, mesenteric cyst, enteric duplication cyst, cystic mesothelioma, or skin appendage tumor. Furthermore, most malignancies in the urachal remnant are intraperitoneal lesions, and generally develop on the anterior aspect of the bladder dome. Moreover, most urachal glandular malignant neoplasms are the mucinous cystic type. We report a cystic urachal adenocarcinoma that presented as an abdominal wall cystic lesion. A 42-year-old woman was admitted to Kangwon National University Hospital for a 5-cm palpable abdominal wall mass. Conservative surgical excision was performed with subsequent histological and immunohistochemical evaluations, but only a few non-mucinous invasive glands and finger-like growths were noted. During a 2-year period, the tumor recurred several times along the urachal tract and metastasized to the regional lymph nodes. Despite receiving chemotherapy, the patient died 2 years after the first surgery.
{"title":"A case of an abdominal wall cystic urachal carcinoma in an unusual location","authors":"K. Kim, Minsun Jung, D. Lim, Young-Joon Ryu","doi":"10.5430/CRCP.V4N3P16","DOIUrl":"https://doi.org/10.5430/CRCP.V4N3P16","url":null,"abstract":"A solitary cystic lesion in the abdominal wall is generally benign, such as an omental cyst, mesenteric cyst, enteric duplication cyst, cystic mesothelioma, or skin appendage tumor. Furthermore, most malignancies in the urachal remnant are intraperitoneal lesions, and generally develop on the anterior aspect of the bladder dome. Moreover, most urachal glandular malignant neoplasms are the mucinous cystic type. We report a cystic urachal adenocarcinoma that presented as an abdominal wall cystic lesion. A 42-year-old woman was admitted to Kangwon National University Hospital for a 5-cm palpable abdominal wall mass. Conservative surgical excision was performed with subsequent histological and immunohistochemical evaluations, but only a few non-mucinous invasive glands and finger-like growths were noted. During a 2-year period, the tumor recurred several times along the urachal tract and metastasized to the regional lymph nodes. Despite receiving chemotherapy, the patient died 2 years after the first surgery.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"4 1","pages":"16"},"PeriodicalIF":0.0,"publicationDate":"2017-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N3P16","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42002898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Warty carcinoma of the uterine cervix is a very rare and specific variant of invasive squamous cell carcinoma, usually described as a hybrid of the features of both condyloma acuminatum and invasive squamous cell carcinoma. The diagnostic pitfalls of this lesion are: 1) the bland appearance of cytomorphology, 2) distinct koilocytotic atypia, and 3) p16 negativity. A case of warty carcinoma with a fungating mass on the uterine cervix of a 75-year-old woman is presented. The original diagnosis by punch biopsy was atypical squamous cells, undetermined for malignancy, adjunct with p16 negativity. The subsequent radical hysterectomy showed a protruding mass (5.7 cm in horizontal dimension) of the uterine cervix. Light microscopy revealed a protruding mass composed of exophytic papillae and inverted nests along the endocervical glands. There were multiple micro-invasive foci (< 1 mm) of tongue like projections at the nest base and slight involvement of the upper vagina and endometrial surface. The p16 immunohistochemical staining yielded negative results. The results of the HPV DNA chip test from paraffin-embedded tissue were 6 (low risk, +++) and 42 (low risk, +). The Ki-67 proliferation index was approximately 20%. The invasive foci and patient’s age were the determining differential factors for malignancy rather than benign condylomatous lesion.
{"title":"p16-negative warty carcinoma of the uterine cervix with superficial invasion to the endometrium: A case report focusing on diagnostic pitfalls","authors":"Hyun-Jung Kim, C. Lee","doi":"10.5430/CRCP.V4N3P12","DOIUrl":"https://doi.org/10.5430/CRCP.V4N3P12","url":null,"abstract":"Warty carcinoma of the uterine cervix is a very rare and specific variant of invasive squamous cell carcinoma, usually described as a hybrid of the features of both condyloma acuminatum and invasive squamous cell carcinoma. The diagnostic pitfalls of this lesion are: 1) the bland appearance of cytomorphology, 2) distinct koilocytotic atypia, and 3) p16 negativity. A case of warty carcinoma with a fungating mass on the uterine cervix of a 75-year-old woman is presented. The original diagnosis by punch biopsy was atypical squamous cells, undetermined for malignancy, adjunct with p16 negativity. The subsequent radical hysterectomy showed a protruding mass (5.7 cm in horizontal dimension) of the uterine cervix. Light microscopy revealed a protruding mass composed of exophytic papillae and inverted nests along the endocervical glands. There were multiple micro-invasive foci (< 1 mm) of tongue like projections at the nest base and slight involvement of the upper vagina and endometrial surface. The p16 immunohistochemical staining yielded negative results. The results of the HPV DNA chip test from paraffin-embedded tissue were 6 (low risk, +++) and 42 (low risk, +). The Ki-67 proliferation index was approximately 20%. The invasive foci and patient’s age were the determining differential factors for malignancy rather than benign condylomatous lesion.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"4 1","pages":"12"},"PeriodicalIF":0.0,"publicationDate":"2017-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N3P12","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46721178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael P. Greenwood, F. J. Hairston, M. Schwartz, Kristi Pepper, Heather L Hendrickson, Anuj Suri, D. Coffey, M. Deavers, R. Olsen, Jessica S. Thomas
Omental extragastrointestinal stromal tumors are rare neoplasms. We present a case of an elderly woman who was found to have a large solid and cystic pelvic mass of presumed ovarian origin with associated omental neovascularity. Histopathologic examination showed a mixed spindled and epithelioid tumor which was essentially negative for c-KIT and positive for smooth muscle markers by immunohistochemistry. A next generation sequencing panel was performed, analyzing the patient’s tumor for actionable mutations in 50 genes commonly associated with human cancers. Identification of a point mutation in PDGFRA enabled accurate diagnosis and provided an option for targeted therapy for this rare tumor.
{"title":"Omental gastrointestinal stromal tumor: Arriving at a diagnosis with therapeutic options in the molecular era","authors":"Michael P. Greenwood, F. J. Hairston, M. Schwartz, Kristi Pepper, Heather L Hendrickson, Anuj Suri, D. Coffey, M. Deavers, R. Olsen, Jessica S. Thomas","doi":"10.5430/CRCP.V4N3P7","DOIUrl":"https://doi.org/10.5430/CRCP.V4N3P7","url":null,"abstract":"Omental extragastrointestinal stromal tumors are rare neoplasms. We present a case of an elderly woman who was found to have a large solid and cystic pelvic mass of presumed ovarian origin with associated omental neovascularity. Histopathologic examination showed a mixed spindled and epithelioid tumor which was essentially negative for c-KIT and positive for smooth muscle markers by immunohistochemistry. A next generation sequencing panel was performed, analyzing the patient’s tumor for actionable mutations in 50 genes commonly associated with human cancers. Identification of a point mutation in PDGFRA enabled accurate diagnosis and provided an option for targeted therapy for this rare tumor.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"4 1","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N3P7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45319460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Jetly, Annapoorani Varadarajan, K. Naik, P. Patel
Background: Epithelioid sarcoma is a rare malignancy that presents diagnostic difficulties. Cases: We report three cases of epithelioid sarcoma with different presentations and clinical course. One patient had a classicaltype epithelioid sarcoma while rest two suffered from the rarer proximal-type. All three underwent surgical excision while two of them also had postoperative adjuvant therapy. The diagnostic challenges and the final outcome has been discussed in detail. Conclusion: The diagnosis of epithelioid sarcoma needs a high index of clinical suspicion and immunohistochemistry is extremely valuable. Adequacy of index surgery affects the ultimate prognosis.
{"title":"Epithelioid sarcoma: A case series of three different presentations","authors":"D. Jetly, Annapoorani Varadarajan, K. Naik, P. Patel","doi":"10.5430/CRCP.V4N3P1","DOIUrl":"https://doi.org/10.5430/CRCP.V4N3P1","url":null,"abstract":"Background: Epithelioid sarcoma is a rare malignancy that presents diagnostic difficulties. Cases: We report three cases of epithelioid sarcoma with different presentations and clinical course. One patient had a classicaltype epithelioid sarcoma while rest two suffered from the rarer proximal-type. All three underwent surgical excision while two of them also had postoperative adjuvant therapy. The diagnostic challenges and the final outcome has been discussed in detail. Conclusion: The diagnosis of epithelioid sarcoma needs a high index of clinical suspicion and immunohistochemistry is extremely valuable. Adequacy of index surgery affects the ultimate prognosis.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":" ","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2017-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N3P1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46900341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present the case of a 56-year-old gentleman who presented with non specific malaise, myalgia and anorexia. Clinical examination revealed a large circumscribed palpable mass in the left iliac fossa. He underwent an intraabdominal pelvic biopsy, computed tomography (CT), magnetic resonance imaging (MRI) of abdominal wall and Positron Emmission Tomography (PET). Differential diagnoses included Gastro Intestinal Stromal Tumour (GIST) and sarcoma. He underwent a laparotomy and excision of the lesion. Histological analysis of the lesion demonstrated a dedifferentiated liposarcoma involving the colon and adjacent pericolic fat. Margins were clear and there was no nodal involvement. He declined adjuvant chemotherapy. He subsequently developed a local recurrence, which was deemed unresectable. He commenced chemotherapy but continued to deteriorate. He received palliative treatment and died 6 months following his initial surgery.
{"title":"Recurrence of a de-differentiated liposarcoma of the colon","authors":"M. Hennessy, J. O'connell, D. Kearney, E. Andrews","doi":"10.5430/CRCP.V4N2P24","DOIUrl":"https://doi.org/10.5430/CRCP.V4N2P24","url":null,"abstract":"We present the case of a 56-year-old gentleman who presented with non specific malaise, myalgia and anorexia. Clinical examination revealed a large circumscribed palpable mass in the left iliac fossa. He underwent an intraabdominal pelvic biopsy, computed tomography (CT), magnetic resonance imaging (MRI) of abdominal wall and Positron Emmission Tomography (PET). Differential diagnoses included Gastro Intestinal Stromal Tumour (GIST) and sarcoma. He underwent a laparotomy and excision of the lesion. Histological analysis of the lesion demonstrated a dedifferentiated liposarcoma involving the colon and adjacent pericolic fat. Margins were clear and there was no nodal involvement. He declined adjuvant chemotherapy. He subsequently developed a local recurrence, which was deemed unresectable. He commenced chemotherapy but continued to deteriorate. He received palliative treatment and died 6 months following his initial surgery.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"4 1","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2017-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N2P24","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43827286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Leung, B. Ezekian, Jonathan P. Galeotti, Diana M. Cardona, D. Blazer
Cellular angiofibromas (CAF) are rare, benign, soft tissue/stromal lesions first described by Nucci et al. in 1997. These masses are well circumscribed, typically small (< 6 cm), and occur mainly in the vulvar region in women and the inguinoscrotal region in men. We present a case of a 60-year-old male who was found to have a very large (20 cm × 13.5 cm × 6 cm) lesion occupying the deep pelvis bridging the pelvic outlet and involving the perineum. Because of diagnostic uncertainty and significant symptomatology, the mass was ultimately resected en bloc with the rectum and anus. Final pathology revealed a large multi-lobulated CAF. This tumor is the largest CAF reported in the literature to date. Furthermore, this mass involved the deep male pelvis with extension between two anatomic compartments which has not been previously described.
{"title":"A giant soft tissue lesion of the male perineum: Unusual presentation of a cellular angiofibroma","authors":"K. Leung, B. Ezekian, Jonathan P. Galeotti, Diana M. Cardona, D. Blazer","doi":"10.5430/CRCP.V4N2P20","DOIUrl":"https://doi.org/10.5430/CRCP.V4N2P20","url":null,"abstract":"Cellular angiofibromas (CAF) are rare, benign, soft tissue/stromal lesions first described by Nucci et al. in 1997. These masses are well circumscribed, typically small (< 6 cm), and occur mainly in the vulvar region in women and the inguinoscrotal region in men. We present a case of a 60-year-old male who was found to have a very large (20 cm × 13.5 cm × 6 cm) lesion occupying the deep pelvis bridging the pelvic outlet and involving the perineum. Because of diagnostic uncertainty and significant symptomatology, the mass was ultimately resected en bloc with the rectum and anus. Final pathology revealed a large multi-lobulated CAF. This tumor is the largest CAF reported in the literature to date. Furthermore, this mass involved the deep male pelvis with extension between two anatomic compartments which has not been previously described.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"4 1","pages":"20"},"PeriodicalIF":0.0,"publicationDate":"2017-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N2P20","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46406477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Overall incidence of invasive fungal infections in solid organ transplant recipients is low with the more common infections being invasive candidiasis, aspergillosis and cryptococosis. Zygomycosis comprises of only 0.2%-1.2% of infections in renal transplant recipients with current recommendations advising against routine prophylaxis. Case: The patient was a 60-year-old male with a history of renal transplant 25 years ago on immunosuppressants, chronic transplant glomerulopathy, squamous cell carcinoma post penectomy and bilateral orchiectomy 2 years ago, controlled diabetes and hypertension who presented with pain in the perineal region for 4 days. On exam he was discovered to be afebrile and had a scrotal skin fold with urethral opening from his previous surgery and 2.5 cm induration and tenderness in the left gluteal fold. He was treated with 5 days of Unasyn. A biopsy was taken to rule out recurrence of squamous cell carcinoma and he was discharged home. The patient returned with worsening perineal pain within 3 days. On exam he had progressive induration with erythema, swelling and tenderness in the perineum. An initial white blood cell count of 15.8 increased to 25.8 and blood cultures remained negative. The computed tomography scan showed diffuse edema in the perineum without any evidence of abscesses. Immunosuppression was held and broad spectrum antibiotics were started. His renal failure progressively worsened eventually requiring continuous renal replacement therapy, intensive care transfer and vasopressor support. The biopsy revealed intermingled fibrous tissue with focal necrosis and no evidence of malignant cells. A repeat incision and debridement (I&D) culture showed growth consistent with mucor. He was started on liposomal amphotericin B and taken to the OR for multiple debridements. Unfortunately he progressed to multisystem organ failure and died after transitioning to comfort care. Conclusions: Invasive fungal infections remain one of the life threatening differentials for cellulitis like skin lesions, especially for patients not responding to antibiotics and those who are immunocompromised. Early cultures and histopathology of lesions should be done for diagnosis and to avoid delays in treatment.
{"title":"Invasive fungal infections: A diagnostic challenge","authors":"Akshjot Puri, M. Chesser, T. Lidner","doi":"10.5430/CRCP.V4N2P15","DOIUrl":"https://doi.org/10.5430/CRCP.V4N2P15","url":null,"abstract":"Introduction: Overall incidence of invasive fungal infections in solid organ transplant recipients is low with the more common infections being invasive candidiasis, aspergillosis and cryptococosis. Zygomycosis comprises of only 0.2%-1.2% of infections in renal transplant recipients with current recommendations advising against routine prophylaxis. Case: The patient was a 60-year-old male with a history of renal transplant 25 years ago on immunosuppressants, chronic transplant glomerulopathy, squamous cell carcinoma post penectomy and bilateral orchiectomy 2 years ago, controlled diabetes and hypertension who presented with pain in the perineal region for 4 days. On exam he was discovered to be afebrile and had a scrotal skin fold with urethral opening from his previous surgery and 2.5 cm induration and tenderness in the left gluteal fold. He was treated with 5 days of Unasyn. A biopsy was taken to rule out recurrence of squamous cell carcinoma and he was discharged home. The patient returned with worsening perineal pain within 3 days. On exam he had progressive induration with erythema, swelling and tenderness in the perineum. An initial white blood cell count of 15.8 increased to 25.8 and blood cultures remained negative. The computed tomography scan showed diffuse edema in the perineum without any evidence of abscesses. Immunosuppression was held and broad spectrum antibiotics were started. His renal failure progressively worsened eventually requiring continuous renal replacement therapy, intensive care transfer and vasopressor support. The biopsy revealed intermingled fibrous tissue with focal necrosis and no evidence of malignant cells. A repeat incision and debridement (I&D) culture showed growth consistent with mucor. He was started on liposomal amphotericin B and taken to the OR for multiple debridements. Unfortunately he progressed to multisystem organ failure and died after transitioning to comfort care. Conclusions: Invasive fungal infections remain one of the life threatening differentials for cellulitis like skin lesions, especially for patients not responding to antibiotics and those who are immunocompromised. Early cultures and histopathology of lesions should be done for diagnosis and to avoid delays in treatment.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"4 1","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2017-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N2P15","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41878974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An adenomyoma of the uterus is a nodular tumor-like mass of benign endometrial glands, endometrioid stroma and smooth muscle tissue. Extra-uterine adenomyoma is an extremely rare tumor. The majority of the cases described was from ovary and located in the pelvis. We present a case of a 70 years old woman with clinical and radiological suspicious of disseminated malignancy. In the abdominal wall, a 5-cm nodule of larger dimension detected by computed tomography-scan was biopsied for accessibility reasons. The morphological and immunohistochemical features of the biopsy led us to propose the diagnosis of an extrauterine adenomyoma. This article reports the 22nd case of extrauterine adenomyoma, a rare and poorly understood tumor that could be imagiologically and clinically indistinguishable from a metastasis.
{"title":"A 22nd case report of extrauterine adenomyoma of the abdominal wall","authors":"R. Sampaio, J. Garcia, C. Macedo, J. Vizcaíno","doi":"10.5430/CRCP.V4N2P11","DOIUrl":"https://doi.org/10.5430/CRCP.V4N2P11","url":null,"abstract":"An adenomyoma of the uterus is a nodular tumor-like mass of benign endometrial glands, endometrioid stroma and smooth muscle tissue. Extra-uterine adenomyoma is an extremely rare tumor. The majority of the cases described was from ovary and located in the pelvis. We present a case of a 70 years old woman with clinical and radiological suspicious of disseminated malignancy. In the abdominal wall, a 5-cm nodule of larger dimension detected by computed tomography-scan was biopsied for accessibility reasons. The morphological and immunohistochemical features of the biopsy led us to propose the diagnosis of an extrauterine adenomyoma. This article reports the 22nd case of extrauterine adenomyoma, a rare and poorly understood tumor that could be imagiologically and clinically indistinguishable from a metastasis.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"4 1","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2017-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V4N2P11","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47933193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. O. Fidelis, I. Edet, Enakirerhi E. Glen, Isiwele M. Edoise, O. Ayodele, Essiet Grace Akanimo, P. D. Ekwere, E. O. Nkposong
Testicular cystadenoma is ranked the second commonest benign neoplasm. Other benign epididymal neoplasms include adenomatoid tumor (most common), leiomyoma, serous (nonpapillary) cystadenoma, cavernous hemangioma, and melanotic neuroectodermal tumor. Adenocarcinoma, mesothelioma, and metastatic renal cell carcinoma are malignant tumors that can affect the epididymis. A 24-year-old male undergraduate with a 3-month history of mildly tender right testicular swelling histologically diagnosed as papillary cystadenoma is presented. This case is presented from our locality as the first of its’ kind; and because it can be a possible manifestation of other diseases like von Hippel- Lindau (VHL) disease.
{"title":"Papillary cystadenoma of right testis: Case report and literature review","authors":"O. O. Fidelis, I. Edet, Enakirerhi E. Glen, Isiwele M. Edoise, O. Ayodele, Essiet Grace Akanimo, P. D. Ekwere, E. O. Nkposong","doi":"10.5430/CRCP.V4N2P8","DOIUrl":"https://doi.org/10.5430/CRCP.V4N2P8","url":null,"abstract":"Testicular cystadenoma is ranked the second commonest benign neoplasm. Other benign epididymal neoplasms include adenomatoid tumor (most common), leiomyoma, serous (nonpapillary) cystadenoma, cavernous hemangioma, and melanotic neuroectodermal tumor. Adenocarcinoma, mesothelioma, and metastatic renal cell carcinoma are malignant tumors that can affect the epididymis. A 24-year-old male undergraduate with a 3-month history of mildly tender right testicular swelling histologically diagnosed as papillary cystadenoma is presented. This case is presented from our locality as the first of its’ kind; and because it can be a possible manifestation of other diseases like von Hippel- Lindau (VHL) disease.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"4 1","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45805698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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