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Clinical Image of 14-Year-Old Female Patient with Fibrous Dysplasia 14岁女性纤维发育不良患者的临床影像
Pub Date : 2018-10-06 DOI: 10.4172/2324-8785.1000344
A. Lagioia
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引用次数: 0
Odontogenic Infection Secondary to Endodontic Treatment Complicated with Masticatory and Temporal Abscess: Case Report 牙髓治疗继发牙源性感染并发咀嚼及颞部脓肿1例
Pub Date : 2018-10-06 DOI: 10.4172/2324-8785.1000347
Mariana Nagata Cavalheiro, L. Lima, Juliana Cristina Mesti, Eric Hiromoto Taninaka, Ricardo Hiroyuki, T. Fujiwara, L. Zambon
Introduction: Odontogenic infection may happen due to toothalveolar infections. The infection can affect the subfascial spaces, especially when affecting the lower molars, although formation of temporal abscesses is unusual. Such abscesses occur with pain, edema, erythema, trismus, fever, and diagnostic confirmation comes from Tomography/Resonance of the Face and laboratory tests. Recommended treatment involves hospitalization, support, empirical antibiotic therapy-Secondarily directed by culture and antibiogram-and surgical drainage.  Objective: To Report an unusual case of complex odontogenic infection and its therapeutic approach. Resumed Report: A 60-year-old female presented pain and edema on left hemi face after endodontic treatment of the second lower molar, treated with oral antibiotics. After five days: clinical worsening, being referred to the Red Cross Hospital–Parana, presenting trismus, edema in left temporal and malar regions, without floating point. Tomography and Resonance of the Face: net collection in anterior region of left masticator and temporal spaces, edema of the masticatory musculature. We have proceeded with hospitalization and treatment with intravenous Ceftriaxone, Clindamycin and corticosteroid for 4 days, without any improvement. Surgical collection drainage conducted in left masticator and temporal spaces, keeping Penrose drain for 5 days. Favorable evolution and hospital discharge followed, with oral antibiotic and corticosteroid therapy for 10 days. Ambulatory denouement: no signs or symptoms of infection, referral to dentist for follow-up. Conclusion: Odontogenic infections can evolve to extensive abscesses, systemic impairment and sepsis. Despite clinical efforts, early diagnosis and surgical approach are the most important measures on complex infections.
引言:牙源性感染可能是由于牙溶解性感染引起的。感染会影响到骨下间隙,尤其是当影响到下臼齿时,尽管颞脓肿的形成是不寻常的。此类脓肿伴有疼痛、水肿、红斑、牙痛、发烧,诊断确认来自面部断层扫描/共振成像和实验室测试。推荐的治疗方法包括住院治疗、支持、经验性抗生素治疗,其次是培养和抗生素检查以及手术引流。目的:报告一例罕见的复杂牙源性感染病例及其治疗方法。复诊报告:一位60岁的女性,在第二颗下磨牙的牙髓治疗后,口服抗生素治疗,左半边脸出现疼痛和水肿。五天后:临床恶化,转诊至巴拉那红十字会医院,表现为三体性,左侧颞部和颧骨水肿,无浮点。面部断层扫描和共振:左侧咀嚼肌和颞间隙前部网状集合,咀嚼肌组织水肿。我们继续住院治疗,静脉注射头孢曲松、克林霉素和皮质类固醇治疗4天,没有任何改善。在左侧咀嚼肌和颞间隙进行外科收集引流,保持Penrose引流5天。随后病情好转,出院,口服抗生素和皮质类固醇治疗10天。门诊结局:无感染迹象或症状,转诊至牙医进行随访。结论:牙源性感染可发展为广泛脓肿、全身损害和败血症。尽管临床上做出了努力,但早期诊断和手术方法是治疗复杂感染的最重要措施。
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引用次数: 0
Effects of Injectable Aminoglycosides on the Auditory Performance of Individuals with Drug Resistant Tuberculosis in Osun State, Nigeria 注射氨基糖苷类药物对尼日利亚Osun州耐药结核病患者听觉表现的影响
Pub Date : 2018-09-19 DOI: 10.4172/2324-8785.1000351
A. Osisanya, A. Adekola, P. Fada
Ototoxicity caused by injectable aminoglycosides are capable of causing cochleotoxicity which is characterised as death of auditory hair cells (hearing loss) and vestibulotoxicity manifesting as balance disorders. Ototoxicity is always as a result of insidious effects of aminoglycosides on auditory system, with a kind of irreversible (permanent) hearing loss which is common among individuals being treated for Drug Resistant Tuberculosis (DRTB). Therefore, this study examined the effect of injectable aminoglycosides on the auditory performance of patients with DRTB in Osun state. Twenty (20) DRTB patients comprising of 14 males and 6 females were purposively selected to participate in this ex post facto research. Instruments used include Otoscope to diagnose infection of the middle ear and outer parts of the ear, Maico ST 20 portable diagnostic audiometer to determine the hearing threshold of the participants, and audiograms to record the test results. Baseline audiometry revealed that 35% of the participants had mild hearing loss before commencement of treatment with injectable aminoglycosides, while 70% of the participants had severe to profound hearing loss after completion of injectable aminoglycosides. 65% of the participants had tinnitus in addition to hearing loss, while 55% had high frequency loss only. Therefore, health workers should ensure that people with DRTB are well educated about the side effects of injectable aminoglycosides and be encouraged to access audiologic follow up and rehabilitation, while alternative injectable drugs with reduced or milder side effects are employed for treatment of Drug Resistant Tuberculosis.
可注射氨基糖苷引起的耳毒性可引起耳蜗毒性,其特征是听觉毛细胞死亡(听力丧失)和前庭毒性,表现为平衡障碍。耳毒性一直是氨基糖苷类药物对听觉系统的潜移默化作用的结果,在耐药结核病(DRTB)患者中常见的一种不可逆(永久性)听力损失。因此,本研究考察了注射氨基糖苷类药物对奥松州DRTB患者听觉表现的影响。有意选择20例DRTB患者参与本事后研究,其中男性14例,女性6例。使用的仪器包括用于诊断中耳和耳外感染的耳镜,用于确定参与者的听力阈值的Maico ST 20便携式诊断听力学仪,用于记录测试结果的听力图。基线听力测量显示,35%的参与者在开始注射氨基糖苷治疗前有轻度听力损失,而70%的参与者在完成注射氨基糖苷治疗后有严重到深度的听力损失。65%的参与者除了听力损失外还有耳鸣,而55%的参与者只有高频听力损失。因此,卫生工作者应确保对耐药结核病患者进行有关可注射氨基糖苷类药物副作用的良好教育,并鼓励他们进行听科学随访和康复,同时使用副作用较小或较轻的可替代注射药物治疗耐药结核病。
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引用次数: 0
MR Imaging Features of Minor Salivary Gland Tumors 微小涎腺肿瘤的MR影像学特征
Pub Date : 2018-09-19 DOI: 10.4172/2324-8785.1000350
A. Kar, ikar, Siu Cheng Loke, J. Goh, T. Tan
Aim: To retrospectively evaluate the MR imaging features of histologically proven minor salivary gland tumors (MSGTs). Materials and Methods: A retrospective review of MR imaging features of 29 histologically proven MSGTs was performed. Results: The commonest site of involvement was base of tongue (n=7) and the commonest pathology was adenoid cystic carcinoma (n=12). All the MSGTs revealed smooth surface with well-defined margins and polypoidal appearance (100% sensitivity, 100%PPV). T2w hyperintensity and enhancement results (ranged from intense to intermediate hyperintensity) were variable. Larger tumors (more than 3.5 cm) had a heterogeneous appearance. Discussion: All MSGTs showed smooth surface, well-defined margins and polypoidal appearance. The T2w hyperintense signal of the MSGTs (ranging from intermediate T2w hyperintensity to intense T2w hyperintensity) and the post contrast enhancement (also ranging from intermediate to intense enhancement) was variable. In the head and neck region, MSGTs need to be differentiated from the more common entities such as squamous cell ancers (SCC) and Lymphoma. While this differentiation is not always easy, orphologically SCCs typically present as locally infiltrative tumors with ill-defined margins. Lymphomas typically present as polypoidal masses with well-defined margins and hence may closely resemble MSGTs. Lymphomas are generally homogeneous masses showing intermediate T2w hyperintensity. Thus differentiation between lymphomas and MSGTs can sometimes be a challenge, however if the mass shows intense T2w hyperintensity with intense enhancement, it could point to a diagnosis of MSGT.
目的:回顾性评价组织学证实的小涎腺肿瘤(MSGTs)的MR影像学特征。材料和方法:回顾性回顾了29例组织学证实的msgt的磁共振成像特征。结果:最常见的受累部位为舌底(n=7),最常见的病理为腺样囊性癌(n=12)。所有msgt显示表面光滑,边缘清晰,呈水螅样外观(100%灵敏度,100% ppv)。T2w高强度和增强结果(从高强度到中等高强度)是可变的。较大的肿瘤(大于3.5 cm)具有异质外观。讨论:所有msgt表面光滑,边缘清晰,呈水螅样外观。msgt的T2w高信号(从中度T2w高信号到强烈T2w高信号)和对比后增强(也从中度到强烈增强)是可变的。在头颈部区域,msgt需要与更常见的实体如鳞状细胞癌(SCC)和淋巴瘤区分开来。虽然这种分化并不容易,但形态学上SCCs通常表现为局部浸润性肿瘤,边界不清。淋巴瘤典型表现为具有明确边界的息肉样肿块,因此可能与msgt非常相似。淋巴瘤一般为均匀肿块,表现为中等T2w高强度。因此,区分淋巴瘤和MSGT有时可能是一个挑战,但如果肿块显示强烈的T2w高强度并强烈强化,则可能提示MSGT的诊断。
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引用次数: 0
Large Cell Neuroendocrine Carcinoma of the Larynx: A Case Report and Review of Literature 喉大细胞神经内分泌癌1例报告及文献复习
Pub Date : 2018-09-19 DOI: 10.4172/2324-8785.1000354
P. Thakur, Shikhar Kumar, V. Verma
Laryngeal neuroendocrine carcinomas (LNEC) constitute <1% of all tumours originating from the larynx and are believed to originate from pluripotential stem cells located in the submucosa of the larynx. It is hard to estimate the true incidence of large-cell neuroendocrine carcinoma (LCNEC) because the WHO classification does not make a distinction between atypical carcinoid tumors and large-cell neuroendocrine carcinoma. In the current classification, laryngeal LCNEC is considered synonymous with atypical carcinoid/moderately-differentiated (Grade II) neuroendocrine carcinoma. This distinction is clinically important as the clinical behavior and response to treatment differs greatly between subtypes. We report a rare case of metastatic LCNEC of subglottic region of larynx who is treated with chemotherapy and radiotherapy and a review of literature on the diagnosis and treatment of these tumors is presented.
喉神经内分泌癌(LNEC)占所有喉源性肿瘤的不到1%,被认为起源于位于喉粘膜下层的多能干细胞。由于WHO的分类没有区分非典型类癌和大细胞神经内分泌癌,因此很难估计大细胞神经内分泌癌(LCNEC)的真实发病率。在目前的分类中,喉部LCNEC被认为是非典型类癌/中分化(II级)神经内分泌癌的同义词。这种区别在临床上很重要,因为临床行为和对治疗的反应在亚型之间差异很大。我们报告一例罕见的喉声门下转移性LCNEC患者,接受化疗和放疗治疗,并回顾有关这些肿瘤的诊断和治疗的文献。
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引用次数: 1
Clinical Efficiency of Castellani Solution for the Treatment of Granular Myringitis Castellani溶液治疗颗粒性Myringitis的临床疗效观察
Pub Date : 2018-04-09 DOI: 10.4172/2324-8785.1000340
T. Gün
This study is designed to observe the clinical efficiency of Castellani solution for the treatment of granular myringitis (GM). We have included 20 patients among which 15 men and 5 women of mean age, 49.7 years; range, 9–77 years; they were diagnosed with GM and treated with Castellani solution. Topical treatment using Castellani solution and otoendoscopy of tympanic membrane were performed and the follow-up period ranged from 3 to 72 months and the mean follow-up period was 14.4 months. 13 patients showed complete resolution of GM after treatment with Castellani solution. However, one patient had a persistent, small, wet lesion residual lesion. Topical application of Castellani solution is a simple and effective treatment for GM. This study confirms the use of Castellani solution for treatment of granular myringitis.
本研究旨在观察Castellani溶液治疗颗粒性myringitis (GM)的临床疗效。我们纳入20例患者,其中男性15例,女性5例,平均年龄49.7岁;范围:9-77岁;诊断为GM,用Castellani溶液治疗。行Castellani溶液外用治疗,鼓膜耳内窥镜检查,随访3 ~ 72个月,平均14.4个月。13例患者经Castellani溶液治疗后GM完全消退。然而,一名患者有一个持续的,小的,湿的残余病变。外用Castellani溶液治疗GM是一种简单有效的治疗方法。本研究证实了Castellani溶液治疗颗粒性myringitis的有效性。
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引用次数: 0
An Unusual Airway Foreign Body: A Cockroach in the Trachea 不寻常的气道异物:气管中的蟑螂
Pub Date : 2018-04-09 DOI: 10.4172/2324-8785.1000337
A. Sheyn, Liu, Gb Shah
We present a case of airway obstruction by an unusual foreign body in a 10 month old male. The child was brought intubated to the emergency room after he was found unconscious and blue by his parents. His older sibling reported a choking episode after he placed a black object in his mouth. Chest x-ray on arrival demonstrated right-sided air trapping but no definite radio-opaque foreign body. Due to difficulty with ventilation and post-obstructive pulmonary edema on initial bronchoscopy, emergent extracorporeal membrane oxygenation (ECMO) was initiated to help stabilize the patient. Subsequent bronchoscopy demonstrated near total obstruction of the mid-trachea by an insect-like object. The object removed appeared to be a common American cockroach. Airway foreign body retrieval is a common part of otolaryngology practice. Most of the time, these foreign bodies are food materials or other inanimate objects. Finding a cockroach in the airway is incredibly rare and only three cases have been reported in the literature. This case also illustrates that ECMO may be considered in a patient too unstable to tolerate temporary withdrawal of ventilatory support for endoscopy. Additionally, rapid diagnosis and treatment is important when caring for a child with suspected foreign body aspiration.
我们报告了一例10个月大的男性因一种不寻常的异物引起的气道阻塞。孩子被父母发现昏迷不醒,脸色发青,随后被插管送往急诊室。他的哥哥报告说,在他把一个黑色物体放进嘴里后,发生了窒息事件。抵达时胸部x光片显示右侧有空气滞留,但没有明确的放射性不透明异物。由于最初支气管镜检查时通气困难和阻塞性肺水肿,启动了紧急体外膜肺氧合(ECMO)以帮助稳定患者。随后的支气管镜检查显示,一个昆虫状物体几乎完全阻塞了气管中段。被移走的物体似乎是一只普通的美国蟑螂。气道异物回收是耳鼻喉科实践中常见的一部分。大多数时候,这些异物是食物材料或其他无生命物体。在气道中发现蟑螂的情况非常罕见,文献中只报道了三例。该病例还表明,ECMO可能被认为适用于过于不稳定的患者,无法耐受暂时停止内窥镜通气支持。此外,在照顾疑似异物吸入的儿童时,快速诊断和治疗非常重要。
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引用次数: 0
Present Situation and Future of Vocal Arts Medicine in China 中国声乐医学的现状与未来
Pub Date : 2018-04-09 DOI: 10.4172/2324-8785.1000341
Han li-yan
Voice Medicine is a discipline that studies the anatomy, development, physiology and pathology related to voice, speech and language, and explores the etiology, mechanism, diagnosis, treatment and prevention of voice related diseases. This review provides a clear view on Present Situation of the Vocal Arts Medicine in China along with its future aspects, where we conclude that vocal arts medicine will have a better future with collaboration and the support from the city, province, and central governments.
语音医学是研究与语音、言语、语言有关的解剖、发育、生理、病理,探讨语音相关疾病的病因、机制、诊断、治疗和预防的一门学科。本文综述了中国声乐医学的现状和未来发展方向,认为在市、省和中央政府的支持下,声乐医学将会有一个更好的未来。
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引用次数: 0
Profile of Sensorineural Hearing Loss in a Sub-Saharan Africa ENT Service 撒哈拉以南非洲耳鼻喉科的感觉神经性听力损失概况
Pub Date : 2018-04-09 DOI: 10.4172/2324-8785.1000338
C. Ndiaye, H. Ahmed, A. Tall, E. Diom, D. Rea, Diouf Ms, S. Maiga, Diallo Mb, A. Mbaye, Barry Mw, Ndiaye Ic
Introduction: Sensorineural hearing loss is linked to the impairment of the sensorineural structures of the hearing system. Sensorineural hearing loss is a topical subject hardly reported in African francophone medical literature. Objectives: To analyze, through a literature review, the features of sensorineural hearing loss, in the context of a sub-Saharan country. Methods: This is a retrospective study covering the period 1 January 2005 to 31 December 2010. We collected four hundred and twenty seven (427) cases of patients with sensorineural hearing loss. We also recorded the Epidemiological, clinical, functional exploration, morphological and therapeutic data. Results: The average age of patients was 40. Children represented 19.20% (n = 82) of the series. The average age during diagnosis was 10 in children. The series included 231 men (54%) and 196 women (46%). The average time to consultation was 54 months. Unilateral deafness represented 10.54% of the cases. The average hearing loss predominated with a rate of 42.70%, representing 5.94% of deafness. The most common etiologies were presbycusis (29.27%), meningitis (5.15%), and malaria (4%). In 47.3% of cases the cause was unknown. Only 1.87% of our patients have received a hearing aid. Conclusion: Sensorineural hearing loss (SNHL) poses etiological diagnosis problems as well as therapeutic management problems. Indeed etiological research and hearing rehabilitation are expensive. These difficulties could be overcome through the development of a program against deafness.
引言:感觉神经性听力损失与听力系统的感觉神经结构受损有关。感觉神经性听力损失是非洲法语国家医学文献中很少报道的一个主题。目的:通过文献综述,分析撒哈拉以南国家感音神经性听力损失的特点。方法:这是一项回顾性研究,涵盖2005年1月1日至2010年12月31日期间。我们收集了427例感音神经性听力损失患者。我们还记录了流行病学、临床、功能探索、形态学和治疗数据。结果:患者平均年龄40岁。儿童占该系列的19.20%(n=82)。儿童诊断期间的平均年龄为10岁。该系列包括231名男性(54%)和196名女性(46%)。咨询的平均时间为54个月。单侧耳聋占10.54%。平均听力损失占主导地位,发生率为42.70%,占耳聋的5.94%。最常见的病因是老年性疾病(29.27%)、脑膜炎(5.15%)和疟疾(4%)。47.3%的病例病因不明。只有1.87%的患者接受过助听器。结论:感觉神经性听力损失(SNHL)既存在病因诊断问题,也存在治疗管理问题。事实上,病因研究和听力康复是昂贵的。这些困难可以通过制定一项针对耳聋的计划来克服。
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引用次数: 0
Langerhans Cell Histiocytosis in Temporal Bone: Case Report 颞骨郎格汉斯细胞组织细胞增多症1例报告
Pub Date : 2018-04-09 DOI: 10.4172/2324-8785.1000339
Ahmed Abdelrahman Abdelziz, N. Osman, M. Gayyed
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by uncontrolled proliferation of Langerhans cells. We report a case of a 5-years old girl with left post auricular swelling, otalagia and otorrhea of 2 month duration, High resolution computed tomography of temporal bone show destructive expanding tissue density mass. Apparent diffusion coefficient is 1.08×10³ mm²/s in diffusion weight magnetic resonance imaging .Post auricular incision revealed a pinkish, firm granulomatous mass occupied middle ear and mastoid Histopathological examination revealed a mixture of Langerhans histocytes and eosinophils. CD1 and S100 are positive in mmunohistochemistry.
郎格罕细胞组织细胞增多症(LCH)是一种罕见的疾病,其特征是郎格罕氏细胞增殖失控。我们报告一例5岁女孩,左耳后肿胀、耳垂和耳漏持续2个月。颞骨的高分辨率计算机断层扫描显示破坏性的扩张组织密度块。在扩散重量磁共振成像中,表观扩散系数为1.08×10³mm²/s。耳后切口显示粉红色,坚固的肉芽肿性肿块占据中耳和乳突。组织病理学检查显示郎格汉斯组织细胞和嗜酸性粒细胞混合。CD1和S100免疫组化阳性。
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引用次数: 0
期刊
Journal of otology & rhinology
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