Pub Date : 2022-10-20DOI: 10.33582/annpediatr.2022.1106
Ali Dinç Bozat, Nurgul Baldemi, Gokhan Berktug Bahadi, E. Calisici, Deniz Yaprak, Belma Saygili Karago
Testicular torsion is a rare medical condition among neonates. Main symptoms are swelling, erythema and pain of the scrotum. It can be both perinatal (diagnosed at birth) and postnatal (diagnosed after birth to 28 days of life). If not treated, atrophy of both involving and/or contra lateral testis can be developed. Still being the main treatment option is surgery, new researches suggest delayed surgery in perinatal torsion because of low rates of salvaging involving testis. We present a perinatal testicular torsion newborn who undergone surgery in third hour of life. Orchioectomy of the effected testis and orchiopexy of the contra lateral testis is performed. To the best of our knowledge, this is the earliest diagnostic time report of a testicular torsion with successful management. Physicians should always alert for testicular torsion in neonatal period, even in delivery room on performing first physical examination of the newborn baby.
{"title":"A Rare Neonatal Testicular Swelling Cause: Neonatal Testicular Torsion","authors":"Ali Dinç Bozat, Nurgul Baldemi, Gokhan Berktug Bahadi, E. Calisici, Deniz Yaprak, Belma Saygili Karago","doi":"10.33582/annpediatr.2022.1106","DOIUrl":"https://doi.org/10.33582/annpediatr.2022.1106","url":null,"abstract":"Testicular torsion is a rare medical condition among neonates. Main symptoms are swelling, erythema and pain of the scrotum. It can be both perinatal (diagnosed at birth) and postnatal (diagnosed after birth to 28 days of life). If not treated, atrophy of both involving and/or contra lateral testis can be developed. Still being the main treatment option is surgery, new researches suggest delayed surgery in perinatal torsion because of low rates of salvaging involving testis. We present a perinatal testicular torsion newborn who undergone surgery in third hour of life. Orchioectomy of the effected testis and orchiopexy of the contra lateral testis is performed. To the best of our knowledge, this is the earliest diagnostic time report of a testicular torsion with successful management. Physicians should always alert for testicular torsion in neonatal period, even in delivery room on performing first physical examination of the newborn baby.","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89944510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-16DOI: 10.33582/annpediatr.2022.1105
F. Yatribi, A. Bentahila, B. Chkirate
NLRP3 gene responsible for an uncontrolled activation of the innate immunity. Objective is to study epidemiological, clinical, genetic, therapeutic and evolutionary characteristics of CAPS. Material and methods: It is a retrospective analysis over 20 years (2000 to 2020) of 10 cases of CAPS, followed by the P-IV service and the pediatric rheumatology consultation at the Rabat children’s hospital. Results: The mean age at diagnosis was 3 years and 7 months with a masculine predominance of 70%. 06 patients were born to consanguineous parents (first degree). Clinical signs were a recurrent fever in 90%, osteo-articular involvement in 90% with patellar hypertrophy in 04 patients, skin signs were found in all patients 100%, neurological involvement in 70%, sensorial disabilities in 10%, dysmorphic facies in 80%, and failure to thrive in 80%. None of our patients had renal amyloidosis. An inflammatory syndrome was present in all patients 100%. Radiography of joints showed a modeling disorder of the femoral metaphysis in 02 patients, osteoporosis in 02 others, epiphyseal remodeling, and irregular ossification of patella in 01 patient. The genetic studies could only be done to one patient, and it revealed a CIAS1 mutation. NSAIDs and corticosteroids were prescribed to 07 patients with good evolution, and 02 patients received biotherapy, after NSAIDs and steroids treatment failure, with clear improvement. Conclusion: CAPS are rare diseases, and they are largely unknown. Diagnostic and therapeutic management should be early and prompt to avoid irreversible complications and improve the quality and expectancy of life.
{"title":"Periodic Syndrome Associated to Cryopyrin: About 10 Cases","authors":"F. Yatribi, A. Bentahila, B. Chkirate","doi":"10.33582/annpediatr.2022.1105","DOIUrl":"https://doi.org/10.33582/annpediatr.2022.1105","url":null,"abstract":"NLRP3 gene responsible for an uncontrolled activation of the innate immunity. Objective is to study epidemiological, clinical, genetic, therapeutic and evolutionary characteristics of CAPS. Material and methods: It is a retrospective analysis over 20 years (2000 to 2020) of 10 cases of CAPS, followed by the P-IV service and the pediatric rheumatology consultation at the Rabat children’s hospital. Results: The mean age at diagnosis was 3 years and 7 months with a masculine predominance of 70%. 06 patients were born to consanguineous parents (first degree). Clinical signs were a recurrent fever in 90%, osteo-articular involvement in 90% with patellar hypertrophy in 04 patients, skin signs were found in all patients 100%, neurological involvement in 70%, sensorial disabilities in 10%, dysmorphic facies in 80%, and failure to thrive in 80%. None of our patients had renal amyloidosis. An inflammatory syndrome was present in all patients 100%. Radiography of joints showed a modeling disorder of the femoral metaphysis in 02 patients, osteoporosis in 02 others, epiphyseal remodeling, and irregular ossification of patella in 01 patient. The genetic studies could only be done to one patient, and it revealed a CIAS1 mutation. NSAIDs and corticosteroids were prescribed to 07 patients with good evolution, and 02 patients received biotherapy, after NSAIDs and steroids treatment failure, with clear improvement. Conclusion: CAPS are rare diseases, and they are largely unknown. Diagnostic and therapeutic management should be early and prompt to avoid irreversible complications and improve the quality and expectancy of life.","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88494564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-20DOI: 10.33582/annpediatr.2022.1102
Zainab Moussaid, Naima Elhafid, C. Mahraoui, H. Tligui, S. Benchekroun
A 9-year-old girl, admitted for hemoptysis with chronic cough and weight loss in a febrile context. The pulmonary Xray showed opacity of the right middle lobe and the thoracic CT showed mediastinal adenopathy necrosé center with focal areas of banded atelectasia. In front of this subacute evolution and the radiological images, tuberculosis was evoked and anti bacillary treatment was started however the phtysiological balance remained negative. After a month of well-conducted treatment, the course was marked by apyréxie and a slight weight gain, but at 3 months, the patient returns for a persistent cough and the appearance of exertion dyspnée. The radio objectivated the persistence of the radiological image and a 2 th thoracic CT an excavated lung disease with medial adenopathy tissue necrotic center. An assessment was requested including negative returned aspergillar serology and bronchoscopy with alveolar broncho lavage with parasitological and bacteriological study. This was in favour of actinomycosis. The child is put on Peni G for 15 days intravenously relaiyée orally by simple amoxicillin for 6 months. Clinical improvement and normalization of chest X-ray is seen with 18-month recoil
一名9岁女孩，因咯血并慢性咳嗽和体重减轻而入院。肺x线示右中叶混浊，胸部CT示纵隔腺病坏死中心伴局灶带状肺不张。在亚急性发展和放射影像前，引起结核并开始抗细菌治疗，但生理平衡仍为阴性。经过一个月的良好治疗后，患者出现了胞质变性和轻微的体重增加，但在3个月时，患者又出现了持续的咳嗽和运动障碍。影像学和胸部第2次CT显示肺部病变伴内侧腺病组织坏死中心。评估要求包括曲霉血清学阴性，支气管镜检查肺泡支气管灌洗，寄生虫学和细菌学研究。这有利于放线菌病。患儿静脉注射Peni G 15天，口服简单阿莫西林6个月。临床改善和胸部x线恢复正常，后坐力为18个月
{"title":"Pulmonary Actinomycosis in Children: A Case Report","authors":"Zainab Moussaid, Naima Elhafid, C. Mahraoui, H. Tligui, S. Benchekroun","doi":"10.33582/annpediatr.2022.1102","DOIUrl":"https://doi.org/10.33582/annpediatr.2022.1102","url":null,"abstract":"A 9-year-old girl, admitted for hemoptysis with chronic cough and weight loss in a febrile context. The pulmonary Xray showed opacity of the right middle lobe and the thoracic CT showed mediastinal adenopathy necrosé center with focal areas of banded atelectasia. In front of this subacute evolution and the radiological images, tuberculosis was evoked and anti bacillary treatment was started however the phtysiological balance remained negative. After a month of well-conducted treatment, the course was marked by apyréxie and a slight weight gain, but at 3 months, the patient returns for a persistent cough and the appearance of exertion dyspnée. The radio objectivated the persistence of the radiological image and a 2 th thoracic CT an excavated lung disease with medial adenopathy tissue necrotic center. An assessment was requested including negative returned aspergillar serology and bronchoscopy with alveolar broncho lavage with parasitological and bacteriological study. This was in favour of actinomycosis. The child is put on Peni G for 15 days intravenously relaiyée orally by simple amoxicillin for 6 months. Clinical improvement and normalization of chest X-ray is seen with 18-month recoil","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90432929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The mortality of severely ill children presenting with life-threatening emergencies remains high in emerging countries. The objective of this study was to evaluate the management of shock in the pediatric emergency department of the CNHU in accordance with WHO guidelines. Methods: The cross-sectional study covered the period from 1 November 2019 to 31 October 2020. All records of children aged 1 month to 18 years, who presented with shock, were analysed after implementation of life-saving measures. Results: The hospital incidence of shock was 2.6%, and its diagnosis was made on admission in 81.2% of cases. The median age of the children was 29.50 months. Septic shock occurred in 50% of cases. Mortality was 50%, related to the presence of fever on admission. The triage and sequence of management was correct. However, the median time to care was 30 minutes, the use of the intraosseous access was non-existent, and traceability should be improved. Conclusion: The introduction of an intraosseous kit is essential in order to reduce management delays. The priority remains the fight against infectious pathologies.
{"title":"Management of Shock in the Pediatric Emergency Unit of the National Teaching Hospital HKM (CNHU-HKM) in Cotonou","authors":"Zohoun L, L. f., D. L.","doi":"10.33582/2637-9627/1080","DOIUrl":"https://doi.org/10.33582/2637-9627/1080","url":null,"abstract":"Introduction: The mortality of severely ill children presenting with life-threatening emergencies remains high in emerging countries. The objective of this study was to evaluate the management of shock in the pediatric emergency department of the CNHU in accordance with WHO guidelines. Methods: The cross-sectional study covered the period from 1 November 2019 to 31 October 2020. All records of children aged 1 month to 18 years, who presented with shock, were analysed after implementation of life-saving measures. Results: The hospital incidence of shock was 2.6%, and its diagnosis was made on admission in 81.2% of cases. The median age of the children was 29.50 months. Septic shock occurred in 50% of cases. Mortality was 50%, related to the presence of fever on admission. The triage and sequence of management was correct. However, the median time to care was 30 minutes, the use of the intraosseous access was non-existent, and traceability should be improved. Conclusion: The introduction of an intraosseous kit is essential in order to reduce management delays. The priority remains the fight against infectious pathologies.","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74908454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Salama, A. Saeed, A. Moussa, M. A. Qubasi, Safaa Al Saige, Shihab Kannappillil, S. Ahmed
Background: HIE remains a significant cause of mortality and long-term disability in late preterm and term newborns. At birth, the only available distinction between mild, moderate, and severe HIE is based on the clinical ground. Nevertheless, mild HIE can be presented with subtle or subjective clinical features which may mislead the treating physician and delay his decision to intervene. Methods: This is a retrospective descriptive study examined all inborn newborns ≥ 35 weeks gestational age born at a single, tertiary level Neonatal Intensive Care Unit (NICU) in women’s hospital. The study revised newborns who were admitted to NICU during the period from November 2014 till November 2020 under the diagnoses of mild HIE. The decision to start therapeutic hypothermia in cases of mHIE was off-label and it was taken according to the clinical judgment of the treating team. Results: Out of the 265 newborns admitted with a history suggestive of HIE or neurological deficits, only 116 newborns matched the diagnosis of mHIE according to the above-mentioned exclusions. 19 newborns out of the 116 mHIE cases received therapeutic hypothermia. Antepartum and or intrapartum complications were recorded in 48 mothers including an infant of insulin-dependent diabetic mother 12, pre-eclampsia 3, cord prolapse 2, shoulder dystocia 2, antepartum hemorrhage 8, chorioamnionitis 6, poor CTG tracing 13, and ruptured uterus 2. Mean gestation was 38±2 weeks, mean birth weight was 3.0±0.5 kg, Cesarean section was 57 % in the un-cooled group vs 75% in the cooled group. Mean Apgar score at 10th minute was 7.9±1.8 vs 5.3±2.2 in the un-cooled vs cooled group, the p-value is 0.002. Arterial cord pH was 7.15±0.3 vs 6.92±0.26. The base deficit in the first-hour blood gas was -7.83±5 vs -12± 5.6 (P=0.005). The Total number of cooled newborns was 19 (16%). Respiratory support was required in 76% of un-cooled newborns vs 95 % of cooled newborns. Most of the newborns have achieved full sucking power within 10 days (99%). Cooled newborns had to stay longer in the NICU because of the added number of cooling where the length of stay was 11±4.7 days vs 6.9±4.7 days in un-cooled newborns. The MRI brain was done on 25 newborns, 12 MRIs were reported as abnormal (48 %) and consistent with hypoxic-ischemic changes, 5/97 in the un-cooled cases and 7 in the cooled cases. Neurodevelopmental assessments at 12 months and 18 months of age were abnormal in 14/116 newborns (12%). Conclusion: The current assumptions about the benignity of mild form of HIE may not be accurate. More attention to this category of HIE, clear diagnostic criteria, longer clinical observation, and vigilant neurological assessment are all required.
背景:HIE仍然是晚期早产儿和足月新生儿死亡和长期残疾的重要原因。出生时，轻度、中度和重度HIE之间唯一可用的区别是基于临床基础。然而，轻度HIE可能表现出微妙或主观的临床特征，这可能会误导治疗医生并延迟他干预的决定。方法:这是一项回顾性描述性研究，调查了在女子医院单一三级新生儿重症监护病房(NICU)出生的所有≥35孕周的新生儿。本研究对2014年11月至2020年11月期间入住NICU诊断为轻度HIE的新生儿进行了修正。在mHIE病例中开始低温治疗的决定是超说明书的，是根据治疗团队的临床判断做出的。结果:在265例有HIE病史或神经功能缺陷的新生儿中，根据上述排除，只有116例新生儿符合mHIE的诊断。116例mHIE病例中有19例新生儿接受了低温治疗。我们记录了48例产前或产时并发症，包括1例胰岛素依赖型糖尿病母亲12例，子痫前期3例，脐带脱垂2例，肩难产2例，产前出血8例，绒毛膜羊膜炎6例，CTG追踪不良13例，子宫破裂2例。平均妊娠38±2周，平均出生体重3.0±0.5 kg，未降温组剖宫产率57%，降温组剖宫产率75%。未冷却组和冷却组10分钟Apgar评分平均值分别为7.9±1.8和5.3±2.2,p值为0.002。动脉血索pH分别为7.15±0.3 vs 6.92±0.26。第1小时血气基础亏缺为-7.83±5 vs -12±5.6 (P=0.005)。新生儿总数为19例(16%)。76%的未降温新生儿需要呼吸支持，而95%的降温新生儿需要呼吸支持。大多数新生儿在10天内达到完全吸吮能力(99%)。降温新生儿在NICU的停留时间为11±4.7天，而未降温新生儿的停留时间为6.9±4.7天。对25例新生儿进行脑MRI检查，12例MRI异常(48%)，符合缺氧缺血性改变，其中5/97为未降温，7例为降温。116个新生儿中有14个(12%)在12个月和18个月时的神经发育评估异常。结论:目前关于轻度HIE良性的假设可能不准确。这类HIE需要更多的关注，明确的诊断标准，更长的临床观察，以及警惕的神经学评估。
{"title":"Outcomes for Newborns with Mild Hypoxic-Ischemic Encephalopathy: A Retrospective Study","authors":"H. Salama, A. Saeed, A. Moussa, M. A. Qubasi, Safaa Al Saige, Shihab Kannappillil, S. Ahmed","doi":"10.33582/2637-9627/1081","DOIUrl":"https://doi.org/10.33582/2637-9627/1081","url":null,"abstract":"Background: HIE remains a significant cause of mortality and long-term disability in late preterm and term newborns. At birth, the only available distinction between mild, moderate, and severe HIE is based on the clinical ground. Nevertheless, mild HIE can be presented with subtle or subjective clinical features which may mislead the treating physician and delay his decision to intervene. Methods: This is a retrospective descriptive study examined all inborn newborns ≥ 35 weeks gestational age born at a single, tertiary level Neonatal Intensive Care Unit (NICU) in women’s hospital. The study revised newborns who were admitted to NICU during the period from November 2014 till November 2020 under the diagnoses of mild HIE. The decision to start therapeutic hypothermia in cases of mHIE was off-label and it was taken according to the clinical judgment of the treating team. Results: Out of the 265 newborns admitted with a history suggestive of HIE or neurological deficits, only 116 newborns matched the diagnosis of mHIE according to the above-mentioned exclusions. 19 newborns out of the 116 mHIE cases received therapeutic hypothermia. Antepartum and or intrapartum complications were recorded in 48 mothers including an infant of insulin-dependent diabetic mother 12, pre-eclampsia 3, cord prolapse 2, shoulder dystocia 2, antepartum hemorrhage 8, chorioamnionitis 6, poor CTG tracing 13, and ruptured uterus 2. Mean gestation was 38±2 weeks, mean birth weight was 3.0±0.5 kg, Cesarean section was 57 % in the un-cooled group vs 75% in the cooled group. Mean Apgar score at 10th minute was 7.9±1.8 vs 5.3±2.2 in the un-cooled vs cooled group, the p-value is 0.002. Arterial cord pH was 7.15±0.3 vs 6.92±0.26. The base deficit in the first-hour blood gas was -7.83±5 vs -12± 5.6 (P=0.005). The Total number of cooled newborns was 19 (16%). Respiratory support was required in 76% of un-cooled newborns vs 95 % of cooled newborns. Most of the newborns have achieved full sucking power within 10 days (99%). Cooled newborns had to stay longer in the NICU because of the added number of cooling where the length of stay was 11±4.7 days vs 6.9±4.7 days in un-cooled newborns. The MRI brain was done on 25 newborns, 12 MRIs were reported as abnormal (48 %) and consistent with hypoxic-ischemic changes, 5/97 in the un-cooled cases and 7 in the cooled cases. Neurodevelopmental assessments at 12 months and 18 months of age were abnormal in 14/116 newborns (12%). Conclusion: The current assumptions about the benignity of mild form of HIE may not be accurate. More attention to this category of HIE, clear diagnostic criteria, longer clinical observation, and vigilant neurological assessment are all required.","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81534634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zohoun L, L. f., Tohodjede Y, A. F., Lankpeko C, D. M.
Objective: The description of COVID-19 in children has evolved over time. We report here its epidemiological, clinical and evolutionary aspects in a hospital setting in sub-Saharan Africa. Methods: The study was prospective cross sectional, from January 1 to June 30, 2021. It included all children from 1 month to 18 years of age, admitted to the pediatric emergency ward of the CNHU HKM of Cotonou, tested positive for SARS-CoV-2 by RT-PCR on nasopharyngeal swabs. At admission, screening of children was targeted, based on symptoms common in children with COVID-19 according to the literature. Results: A total of 93 children were screened during the period, among which 18 were positive for SARS-CoV-2. The hospital frequency was 2% (18/895). The median age was 11 months. The most common symptoms were fever, cough, and shortness of breath. Half of the children had comorbidities, including heart disease, sickle cell disease, and nephrotic syndrome. The moderate form was the most frequent with pneumonia (10/18). The severe form was present in 2 children. Malaria was associated in 2 cases. The evolution was favorable in 17 children, after a mean hospitalization time of 5.81±2.74 days. One 4-month-old infant, with suspected multisystem inflammatory syndrome (MIS-C) died. Conclusion: The evolution of COVID-19 in children is benign, but severe forms are possible. A systematic screening should be proposed to all febrile children admitted to the emergency room.
{"title":"COVID-19 in Children at the National Teaching Hospital of Cotonou: Epidemiology, Clinic, and Therapy","authors":"Zohoun L, L. f., Tohodjede Y, A. F., Lankpeko C, D. M.","doi":"10.33582/2637-9627/1078","DOIUrl":"https://doi.org/10.33582/2637-9627/1078","url":null,"abstract":"Objective: The description of COVID-19 in children has evolved over time. We report here its epidemiological, clinical and evolutionary aspects in a hospital setting in sub-Saharan Africa. Methods: The study was prospective cross sectional, from January 1 to June 30, 2021. It included all children from 1 month to 18 years of age, admitted to the pediatric emergency ward of the CNHU HKM of Cotonou, tested positive for SARS-CoV-2 by RT-PCR on nasopharyngeal swabs. At admission, screening of children was targeted, based on symptoms common in children with COVID-19 according to the literature. Results: A total of 93 children were screened during the period, among which 18 were positive for SARS-CoV-2. The hospital frequency was 2% (18/895). The median age was 11 months. The most common symptoms were fever, cough, and shortness of breath. Half of the children had comorbidities, including heart disease, sickle cell disease, and nephrotic syndrome. The moderate form was the most frequent with pneumonia (10/18). The severe form was present in 2 children. Malaria was associated in 2 cases. The evolution was favorable in 17 children, after a mean hospitalization time of 5.81±2.74 days. One 4-month-old infant, with suspected multisystem inflammatory syndrome (MIS-C) died. Conclusion: The evolution of COVID-19 in children is benign, but severe forms are possible. A systematic screening should be proposed to all febrile children admitted to the emergency room.","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"469 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83046298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unusual presentation of a choledochal cyst","authors":"Niloy Ghosh, J. Nirgiotis, J. Meller","doi":"10.33582/2637-9627/1007","DOIUrl":"https://doi.org/10.33582/2637-9627/1007","url":null,"abstract":"","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"240 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74487753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-28DOI: 10.4172/0032-745X.1000300
Hui We, Fangfang Qu, Lei Sun, Yajie Lei, Rui Wang
Introduction: Pneumonia is a common acute disease of the respiratory tract in childhood. In this paper, 700 cases of pneumonia in Changan Hospital of Xi’an city [1-3] were summarized. All seasons are easy to occur, especially in winter and spring. It is easy to recurrent attacks affect the growth and development of children, if the treatment is not complete. The clinical data of the children are reported as follows: Background: From January 2016 to December 2016, 700 cases of children pneumonia in Changan hospital in Xi’an were investigated in 1 pairs of 1 [4]. Among the 700 children, 437 were boys and 263 were women; 252 cases aged 2 were occupied 23%. Accessory Examination: In 700 cases of chest radiography，23 cases of lobar pneumonia accounted for 3.28% of the total. 87 cases of double pulmonary bronchitis were 12.42%, 488 cases of bronchitis were 69.71%, 11 cases of interstitial pneumonia were 15.71%,and 4 cases of lobule in chest.198 cases of WBC ≥ 10 were 28.28%, 76 cases of neutrophils ≥ 70 were 10.86%,402cases of lymphoid ≥ 40 were 57.43%, 267 cases of mononuclear ≥ 10 were 38.14%.196 cases of syncytial virus positive were took up 28%,4 cases of adenovirus positive were made up 0.57%, 3 cases of influenza virus positive were occupied 0.43% [5-7]. Complication: 2 cases of combined respiratory failure accounted for 0.28%,13 cases of combined enteritis were 1.85%,8 cases of combined myocardial injury were 1.14%, 1 case of combined heart failure were 0.14%,1 case of combined Anemia were 0.14%,2 cases of combined laryngitis were 0.28%. Treatment: 368 cases of the second generation cephalosporin’s +antivirus were 52.57%,183 cases of the third generation cephalosporin’s + antivirus were 26.14%,129 cases of Cephalosporin +Archie were 18.43%, 20 cases of Penicillin + antiviral were 2.85%,23 cases of >14 days of treatment were 3.28%,72 cases of 7-10 days of treatment were 10.28%,545 cases of 5-7 days of treatment were 77.86%, 60 cases of <5 days of treatment were 8.57%. Result: Treatment, Infantile pneumonia is the main anti infection and treat the complications. At the time of anti-infection, a wide range of antimicrobial spectrum, less drug resistant bacteria, and low toxicity of liver and kidney are used, combined use of two kinds of broad-spectrum antibiotics, Such as cephalosporin’s, macrolides,and antiviral drugs, and give oxygen therapy, nutritional support, Correcting the acid-base balance and electrolyte disturbance in some children, actively dealing with the complications and avoiding heart failure.
{"title":"Clinical study and analysis of 700 cases of pneumonia in children","authors":"Hui We, Fangfang Qu, Lei Sun, Yajie Lei, Rui Wang","doi":"10.4172/0032-745X.1000300","DOIUrl":"https://doi.org/10.4172/0032-745X.1000300","url":null,"abstract":"Introduction: Pneumonia is a common acute disease of the respiratory tract in childhood. In this paper, 700 cases of pneumonia in Changan Hospital of Xi’an city [1-3] were summarized. All seasons are easy to occur, especially in winter and spring. It is easy to recurrent attacks affect the growth and development of children, if the treatment is not complete. The clinical data of the children are reported as follows: \u0000 Background: From January 2016 to December 2016, 700 cases of children pneumonia in Changan hospital in Xi’an were investigated in 1 pairs of 1 [4]. Among the 700 children, 437 were boys and 263 were women; 252 cases aged 2 were occupied 23%. \u0000 Accessory Examination: In 700 cases of chest radiography，23 cases of lobar pneumonia accounted for 3.28% of the total. 87 cases of double pulmonary bronchitis were 12.42%, 488 cases of bronchitis were 69.71%, 11 cases of interstitial pneumonia were 15.71%,and 4 cases of lobule in chest.198 cases of WBC ≥ 10 were 28.28%, 76 cases of neutrophils ≥ 70 were 10.86%,402cases of lymphoid ≥ 40 were 57.43%, 267 cases of mononuclear ≥ 10 were 38.14%.196 cases of syncytial virus positive were took up 28%,4 cases of adenovirus positive were made up 0.57%, 3 cases of influenza virus positive were occupied 0.43% [5-7]. \u0000Complication: 2 cases of combined respiratory failure accounted for 0.28%,13 cases of combined enteritis were 1.85%,8 cases of combined myocardial injury were 1.14%, 1 case of combined heart failure were 0.14%,1 case of combined Anemia were 0.14%,2 cases of combined laryngitis were 0.28%. \u0000Treatment: 368 cases of the second generation cephalosporin’s +antivirus were 52.57%,183 cases of the third generation cephalosporin’s + antivirus were 26.14%,129 cases of Cephalosporin +Archie were 18.43%, 20 cases of Penicillin + antiviral were 2.85%,23 cases of >14 days of treatment were 3.28%,72 cases of 7-10 days of treatment were 10.28%,545 cases of 5-7 days of treatment were 77.86%, 60 cases of <5 days of treatment were 8.57%. \u0000Result: Treatment, Infantile pneumonia is the main anti infection and treat the complications. At the time of anti-infection, a wide range of antimicrobial spectrum, less drug resistant bacteria, and low toxicity of liver and kidney are used, combined use of two kinds of broad-spectrum antibiotics, Such as cephalosporin’s, macrolides,and antiviral drugs, and give oxygen therapy, nutritional support, Correcting the acid-base balance and electrolyte disturbance in some children, actively dealing with the complications and avoiding heart failure.","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89762747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zika virus is a flavivirus known to cause microcephaly during development. The mechanism underlying Zika virus-induced neuropathogenesis is still poorly understood. Recent studies have utilized the cutting edge cell culture and animal model technologies to elucidate factors contributing to Zika virus-associated microcephaly. While future work is needed, current studies have suggested three main factors that contribute to Zika virus pathology: viral lineage, host immunity, and pregnancy stages. This mini review will focus on some of the recent findings that advanced our knowledge in Zika virus-associated microcephaly.
{"title":"Microcephaly in Zika Virus Infection.","authors":"Erica L McGrath, Ping Wu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Zika virus is a flavivirus known to cause microcephaly during development. The mechanism underlying Zika virus-induced neuropathogenesis is still poorly understood. Recent studies have utilized the cutting edge cell culture and animal model technologies to elucidate factors contributing to Zika virus-associated microcephaly. While future work is needed, current studies have suggested three main factors that contribute to Zika virus pathology: viral lineage, host immunity, and pregnancy stages. This mini review will focus on some of the recent findings that advanced our knowledge in Zika virus-associated microcephaly.</p>","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"5 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699379/pdf/nihms-1808868.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40706982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lydia H Pecker, Michael Roth, Sari Landman, Leslie Cunningham, Ellen Johnson Silver, Deepa Manwani
Adolescents with sickle cell disease (SCD) and their parents are more optimistic about their future than their physicians. This may affect treatment preferences and therapy adherence. Disease specific recommendations for discussing disease course of children with SCD do not exist. To begin to address this gap, we held focus groups for adolescents with SCD 14-21 years old (n=6), parents of adolescents with SCD (n=4) and with pediatric (n=3) and adult (n=2) hematologists. SCD prognosis is complicated due to the uncertain disease course. Fear and worry are associated with discussing the future. Parents disagree with adolescents and hematologists about the best approach to discussing prognosis and oppose prognosticating that includes life expectancy. Guidelines to improve communication between physicians and families are needed.
{"title":"Communicating Prognosis in Sickle Cell Disease: A Qualitative Study of Adolescents with Sickle Cell Disease, Their Parents and Providers.","authors":"Lydia H Pecker, Michael Roth, Sari Landman, Leslie Cunningham, Ellen Johnson Silver, Deepa Manwani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Adolescents with sickle cell disease (SCD) and their parents are more optimistic about their future than their physicians. This may affect treatment preferences and therapy adherence. Disease specific recommendations for discussing disease course of children with SCD do not exist. To begin to address this gap, we held focus groups for adolescents with SCD 14-21 years old (n=6), parents of adolescents with SCD (n=4) and with pediatric (n=3) and adult (n=2) hematologists. SCD prognosis is complicated due to the uncertain disease course. Fear and worry are associated with discussing the future. Parents disagree with adolescents and hematologists about the best approach to discussing prognosis and oppose prognosticating that includes life expectancy. Guidelines to improve communication between physicians and families are needed.</p>","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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