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Using the Neuroadaptagen KB200z™ to Ameliorate Terrifying, Lucid Nightmares in RDS Patients: the Role of Enhanced, Brain-Reward, Functional Connectivity and Dopaminergic Homeostasis. 使用 Neuroadaptagen KB200z™ 改善 RDS 患者的恐怖、迷糊噩梦:增强、脑奖赏、功能连接和多巴胺能平衡的作用。
Pub Date : 2015-01-01 DOI: 10.17756/jrds.2015-006
Thomas McLaughlin, Kenneth Blum, Marlene Oscar-Berman, Marcelo Febo, Zsolt Demetrovics, Gozde Agan, James Fratantonio, Mark S Gold

Background: Lucid Dreams are a form of dream life, during which the dreamer may be aware that he/she is dreaming, can stop/re-start the dreams, depending on the pleasantness or unpleasant nature of the dream, and experiences the dream as if he/she were fully awake. Depending on their content, they may be pleasant, un-pleasant or terrifying, at least in the context of patients, who also exhibit characteristics of Reward Deficiency Syndrome (RDS) and Posttraumatic Stress Disorder (PTSD).

Case series: We present eight clinical cases, with known substance abuse, childhood abuse and diagnosed PTSD/RDS. The administration of a putative dopamine agonist, KB200Z™, was associated with the elimination of unpleasant and/or terrifying, lucid dreams in 87.5% of the cases presented, whereas one very heavy cocaine abuser showed a minimal response. These results required the continuous use of this nutraceutical. The lucid dreams themselves were distinguishable from typical, PTSD nightmares insofar as their content did not appear to reflect a symbolic rendition of an originally-experienced, historical trauma. Each of the cases was diagnosed with a form of RDS, i.e., ADHD, ADD, and/or Tourette's syndrome. They all also suffered from some form of Post-Traumatic-Stress-Disorder (PTSD) and other psychiatric diagnoses as well.

Conclusion: The reduction or elimination of terrifying Lucid Dreams seemed to be dependent on KB220Z, whereby voluntary stopping of the agent results in reinstatement of the terrifying non-pleasant nature of the dreams. Following more required research on a much larger population we anticipate confirmation of these seemingly interesting observations. If these results in a small number of patients are indeed confirmed we may have found a frontline solution to a very perplexing and complicated symptom known as lucid dreams.

背景介绍清醒梦是梦境生活的一种形式,做梦者可以意识到自己在做梦,可以根据梦境的愉快或不愉快停止/重新开始做梦,并像完全清醒一样体验梦境。根据梦的内容,这些梦可能是令人愉快的、不令人愉快的或令人恐惧的,至少在患者同时表现出奖赏缺失综合症(RDS)和创伤后应激障碍(PTSD)特征的情况下是这样:我们介绍了八个临床病例,这些患者已知有药物滥用、童年受虐待和创伤后应激障碍/RDS 诊断。在87.5%的病例中,服用假定的多巴胺激动剂KB200Z™后,不愉快和/或恐怖的清晰梦境得以消除,而一名可卡因重度滥用者的反应微乎其微。这些结果要求持续使用这种营养保健品。清醒梦本身有别于典型的创伤后应激障碍噩梦,因为它们的内容似乎并不反映最初经历过的历史创伤的象征性再现。每个病例都被诊断患有某种形式的 RDS,即多动症、注意力缺失症和/或抽动秽语综合征。他们还都患有某种形式的创伤后应激障碍(PTSD)和其他精神疾病:结论:减少或消除可怕的迷梦似乎取决于 KB220Z,自愿停止使用该药剂会导致恢复可怕的非令人愉快的梦境。在对更多人进行更必要的研究后,我们预计这些看似有趣的观察结果将得到证实。如果这些在少数患者身上得出的结果确实得到了证实,那么我们可能已经找到了解决清醒梦这一令人困惑的复杂症状的一线方案。
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Journal of reward deficiency syndrome
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