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Study of Red Ginseng Preparation HRG80 for Relieving Muscle Pain/Soreness and Supporting the Neuromuscular Performance of Elite Weightlifters in Intense Resistance Exercise: An Open-Label, Randomized, Crossover Trial 红参制剂HRG80缓解肌肉疼痛/酸痛和支持优秀举重运动员在高强度阻力运动中的神经肌肉表现的研究:一项开放标签、随机、交叉试验
Pub Date : 2022-11-15 DOI: 10.26420/physmedrehabilint.2022.1207
Hovhannisyan As, Mosinyan Dn, Hayrumyan Sa, Panossian Ag
This study aimed to assess the efficacy of new Panax ginseng C.A.Mey preparation of increased bioavailability in fatigue assessed as relief of muscle soreness and improving the neuromuscular performance of healthy subjects following a bout of intense resistance exercise. The effects of the hydroponically cultivated red ginseng root powder HRG80TM (RG) γ-Cyclodextrin -based chewable tablets and cyclodextrin-free RG capsules were compared in an openlabel, randomized, crossover trial on 20 elite weightlifters. The RG treatments for 10 days have a statistically significant effect on the relief of the muscle’s soreness compared to the control. No statistically significant difference was observed in the effects of two capsules vs. one tablet suggesting that γ-Cyclodextrin based chewable tablets of red ginseng preparation HRG80 are almost 4-fold active of cyclodextrin-free HRG80 capsules. Furthermore, the effect of tablets vs. control was significant on the 5th day of the treatment, while the effect of capsules vs. control was observed three days later - on the 8th day. However, in push-ups on the uneven bars (PUB) test of neuromuscular performance, the capsule intake results in increased physical performance compared to tablets or control with maximal effect on the 7th day of treatment. The results of this study provide evidence for the efficacy of γ-cyclodextrin-based chewable tablets containing 100 mg of red ginseng HRG80TM for relief of muscle soreness and supporting the neuromuscular performance of healthy subjects in intense resistance exercise.
本研究旨在评估新人参C.A.Mey制剂在疲劳中提高生物利用度的功效,评估其缓解肌肉酸痛和改善健康受试者在一次高强度阻力运动后的神经肌肉表现。采用开放标签、随机交叉试验,比较了水培红参根粉HRG80TM (RG) γ-环糊精咀嚼片和不含环糊精的RG胶囊对20名优秀举重运动员的影响。与对照组相比,RG治疗10天对肌肉酸痛的缓解有统计学上显著的影响。红参制剂HRG80含γ-环糊精咀嚼片的活性几乎是不含环糊精的HRG80胶囊的4倍。此外,片剂与对照组的效果在治疗的第5天显着,而胶囊与对照组的效果在3天后-第8天观察到。然而,在高低杠俯卧撑(PUB)神经肌肉性能测试中,与片剂或对照组相比,胶囊摄入导致身体性能提高,并在治疗的第7天达到最大效果。本研究结果为含100 mg红参HRG80TM的γ-环糊精咀嚼片在大强度抗阻运动中缓解肌肉酸痛和支持神经肌肉功能的有效性提供了证据。
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引用次数: 0
Decannulation Timing is an Expression of Neurological Recovery Time: The Need to Define a Performance within a Time Frame 脱管时间是神经恢复时间的一种表达:需要在一个时间框架内定义一个性能
Pub Date : 2022-11-07 DOI: 10.26420/physmedrehabilint.2022.1206
Lombardi F, B. A, C. G., M. P, Massobrio M, Lusuardi M
Introduction: The factors that influence the likelihood of tracheostomy tube weaning in patients with severe acquired brain injury (sABI) are fairly well known, and recently it has been pointed out that improving swallowing and cough resistance are among the most important. What has not yet been focused on is the “passage of time” factor and how much it affects weaning opportunities. Objective: With this study, we wanted to analyze how the probability of decannulation varies over time, consistent with neurological improvement. Method: We examined the tracheostomy database of our neurological rehabilitation unit, which reports data from 359 patients with sABI, hospitalized between 2000 and 2012, and all carriers of tracheostomy tube upon admission. The sample was divided into two groups based on the time gap between the acute event and admission to rehabilitation, an Early Group = 60 days and a Late Group > 60 days. The probability of decannulation, both overall and subdivided by groups, was then evaluated. Results: The E-Group showed better functional scores at discharge and a better percentage of decannulation compared with the L-Group. The differences were statistically significant, but later decannulations were not unusual: 12% late weanings versus 88% earlier. The probability of decannulation increases over time and is a factor dependent on the degree of neurological and functional recovery. It is of primary importance to consider these aspects when making comparisons between different centers, defining a product standard or performing benchmarking analyses. Conclusions: The rehabilitative prognosis for decannulation can be reliably judged only after a suitable and well-defined period of time, because the probability of tube weaning has been shown to be strongly dependent on the amount of time that passes. This study also showed that effective decannulations can be achieved even more than 6 months after the acute event, although with significantly lower probabilities.
影响严重获得性脑损伤(sABI)患者气管造口管脱机可能性的因素是相当众所周知的,最近有研究指出,改善吞咽和咳嗽抵抗力是最重要的因素之一。目前尚未关注的是“时间的流逝”因素,以及它对断奶机会的影响程度。目的:通过这项研究,我们想分析脱管的概率如何随时间变化,与神经系统的改善相一致。方法:我们查阅了我院神经康复科气管造口术数据库,该数据库报告了2000年至2012年住院的359例sABI患者的数据,以及入院时气管造口管的所有携带者。根据急性发作至入院康复的时间间隔将样本分为两组,早期组= 60天,晚期组= 60天。然后评估总体和分组的脱管概率。结果:与l组相比,e组出院时功能评分较高,脱管率较高。差异在统计学上是显著的,但较晚断奶并不罕见:12%的断奶时间较晚,而88%的断奶时间较早。脱管的可能性随着时间的推移而增加,这是一个依赖于神经和功能恢复程度的因素。在不同中心之间进行比较、定义产品标准或执行基准分析时,考虑这些方面是最重要的。结论:只有在一段合适且明确的时间后才能可靠地判断脱管的康复预后,因为已证明脱管的概率强烈依赖于所经过的时间。该研究还表明,即使在急性事件发生6个月后,也可以实现有效的脱管,尽管概率明显较低。
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引用次数: 0
Vincer EMO Project: Physical Activity for Haemophilic Patients. How We Faced Up SARS COV2 Pandemic Vincer EMO项目:血友病患者的体育活动。我们如何面对严重急性呼吸系统综合征冠状病毒2型疫情
Pub Date : 2022-10-06 DOI: 10.26420/physmedrehabilint.2022.1205
Valeri F, Borchiellini A, D. C., Bardetta M, S. C, Merli P, Galizia M, Agostino S, Cunsolo N, Maffia M, Zanon F, Bruno B, Massazza G
The SARS COVID pandemic has negatively impacted health care activities in the entire world, both in emergency and ordinary inpatient and outpatient regimes. Rehabilitation has also suffered a heavy penalty which has not spared research projects in specific sectors. The VINCEREMO project stems from the need to objectively evaluate the benefits of a regular personalized physical activity program on musculoskeletal health in patients with severe haemophilia A and B. These patients present in a high percentage of important functional limitations and reduction of trophism and muscle strength due to the consequences of haemophilic arthropathy. Multi-district impairments in addition with the high risk of bleeding hinder the performance of common recreational and sports activities, resulting in social isolation of patients, especially in childhood and youth age. Even if the SARS COVID pandemic interrupted the various rehabilitation activities in the expected mode of the project, we were also able to continue the training course thanks to personalized tele-rehabilitation programs, who supported patients during the lockdown period, maintaining good adherence to therapeutic proposals. The preliminary results of the controls at the end of the reference period showed positive changes in the outcome indicators.
严重急性呼吸系统综合征新冠肺炎疫情对全世界的医疗保健活动产生了负面影响,包括急诊、普通住院和门诊。康复也受到了沉重的惩罚,这也未能放过特定部门的研究项目。VINCEREMO项目源于客观评估定期个性化体育活动计划对严重血友病a和B患者肌肉骨骼健康的益处的需要。由于血友病关节病的后果,这些患者存在很大比例的重要功能限制和营养不良和肌肉力量的减少。多地区的损伤加上出血的高风险,阻碍了常见的娱乐和体育活动的进行,导致患者的社会孤立,尤其是在儿童和青少年时期。即使严重急性呼吸系统综合征新冠肺炎疫情以预期的项目模式中断了各种康复活动,由于个性化的远程康复计划,我们也能够继续培训课程,他们在封锁期间为患者提供支持,并保持了对治疗建议的良好遵守。对照组在参考期结束时的初步结果显示,结果指标发生了积极变化。
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引用次数: 0
Risk Assessment System of Fall in the Elderly Using Artificial Intelligence and Cloud Computing 基于人工智能和云计算的老年人跌倒风险评估系统
Pub Date : 2022-08-17 DOI: 10.26420/physmedrehabilint.2022.1204
Blasco-García Jd, P. N, López-Riquelme Ja, Feliu-Batlle Jj, Nieto-Galera R, Herrero Mt
This paper presents a Cloud-based online tool for helping health professionals to predict the risk of falling in the elderly by using the well-known Tinetti’s Test. This tool implements a Deep Learning-based method for allowing several Tinetti scale’s items to be automatically estimated, simply using a conventional camera or a recorded video. From these sources of information, patients’ skeleton is recognized and their movements analyzed by applying some geometric calculations, which provide an objective risk assessment. Results are represented as a set of plots easily interpretable by experts. Several tests, in a controlled environment, have been carried out to validate the accuracy and reliability of the system. Moreover, some tests have been also made with real elderly patients, whose results have been evaluated by therapists. The benefits of using such remote tool for assessing (objective) fall risk, from a usability point of view, are also highlighted.
本文介绍了一种基于云的在线工具,通过使用著名的蒂内蒂测试来帮助卫生专业人员预测老年人跌倒的风险。这个工具实现了一种基于深度学习的方法,允许自动估计几个蒂内蒂量表的项目,只需使用传统的相机或录制的视频。从这些信息来源中,通过应用一些几何计算来识别患者的骨骼和分析他们的运动,从而提供客观的风险评估。结果被表示为一组易于专家解释的图。在受控环境中进行了多次测试,以验证系统的准确性和可靠性。此外,还对真正的老年患者进行了一些测试,其结果已由治疗师进行了评估。从可用性的角度来看,使用这种远程工具来评估(客观)坠落风险的好处也得到了强调。
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引用次数: 0
Short Wave Diathermy (SWD) Therapy in Patients with Adhesive Capsulitis of Shoulder 短波热疗(SWD)治疗肩胶粘性囊炎
Pub Date : 2022-08-11 DOI: 10.26420/physmedrehabilint.2022.1203
H. A, Khan Zi
Introduction: There are several options for the management of adhesive capsulitis. Short Wave Diathermy (SWD) is also an important option for adhesive capsulitis management, but very few data are available to support SWD use in adhesive capsulitis. Therefore, we studied the effectiveness of SWD to improve the pain and range of motions in frozen shoulder. Methods: A total 56 patients with adhesive capsulitis were selected in this randomized controlled trial for a study period of 6 months. The subjects were divided into two intervention groups; one group with conventional treatment plan plus SWD and second group with conventional treatment alone. Visual Analogue Scale (VAS) with Tenderness Grading (TG) and Shoulder Pain And Disability Index scoring (SPADI) were used to measure the pain and disability, The SPSS (version 20) was used for the statistical analysis; differences between the intervention groups were determined by independent t-test. Results: Among 56 patients, male and female gender were matched (p>0.05) and male to female ratio was 1.66: 1. Only one patient had both shoulders involvement, 48.2% of subjects had right sided and 50.0% had left sided involvement. There were 92.7% of patients who had localized pain and only 7.3% had radiating pain. About 56.4% of the patients had evening time of onset of the pain and 43.6% at night. Most of the patients in both groups had constant and intermittent type of pain, 47.5% and 45.5% respectively, and other types were sharp and dull. Significant differences were observed in VAS, TG and SPADI analysis in between Group A and Group B at week 2, 4 and 6 (P<0.05), whereas initial follow-up was non-significant in VAS and TG analysis (p>0.05). Conclusion: We conclude that when SWD is combined with conventional management of adhesive capsulitis, it gives better reduction in shoulder pain and disability.
导言:有几种治疗粘连性囊炎的方法。短波透热(SWD)也是治疗粘连性胶囊炎的重要选择,但很少有数据支持SWD在粘连性胶囊炎中的应用。因此,我们研究了SWD对改善冻结肩疼痛和活动范围的有效性。方法:选择56例粘连性囊炎患者进行随机对照试验,为期6个月。受试者被分为两个干预组;一组采用常规治疗方案加SWD治疗,另一组单独采用常规治疗。采用视觉模拟量表(Visual Analogue Scale, VAS)、压痛评分(Tenderness Grading, TG)和肩痛与失能指数评分(Shoulder Pain and Disability Index, SPADI)对疼痛和失能进行测量,采用SPSS (version 20)软件进行统计分析;干预组间差异采用独立t检验。结果:56例患者男女性别匹配(p < 0.05),男女比例为1.66:1。只有1例患者双肩受累,48.2%的患者右侧受累,50.0%的患者左侧受累。92.7%的患者有局限性疼痛,只有7.3%的患者有放射性疼痛。56.4%的患者发生于夜间,43.6%的患者发生于夜间。两组患者均以持续型和间歇性疼痛为主,分别占47.5%和45.5%,其他类型为尖锐型和钝感型。A组与B组在第2、4、6周VAS、TG、SPADI分析差异均有统计学意义(P0.05)。结论:我们的结论是,当SWD与粘连性囊炎的常规治疗相结合时,它可以更好地减少肩部疼痛和残疾。
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引用次数: 1
Neurophysiological Examination of the Effects of Behavioral Antecedents on Physical Balance in Older Individuals 行为前体对老年人身体平衡影响的神经生理学检查
Pub Date : 2022-07-29 DOI: 10.26420/physmedrehabilint.2022.1202
Kodama T, A. T., Matsuo N, Yamaguchi H
Falls in older individuals can be caused by balance disorders, influenced by predictive factors based on self-efficacy and outcome expectation. This study investigated the relationship between predictive factors related to regional neural functional activity and postural control. We included 16 older men (average age, 76.4±5.8 years) and evaluated their balancing ability and fall-related selfefficacy using the Japanese version of Mini-Balance Evaluation Systems Test (J-Mini-BESTest) and the Japanese version of the Falls Efficacy Scale (JFES), respectively. We performed an electroencephalogram before, during, and after postural perturbations. The cortical activity in the right Inferior Parietal Lobe (IPL) and Supplementary Motor Area (SMA) was analyzed using current density in the specific regions of interest. Foot Response Values (FRV) were used to evaluate physical responses during postural perturbations. The neural activity values in the IPL after postural perturbations indicated a significant positive correlation with JFES and J-Mini-BESTest scores when prior information was provided to participants. The neural activity values in the SMA before postural perturbations showed a significant positive correlation with J-Mini-BESTest score and a significant negative correlation with FRV. Furthermore, during postural perturbations, subjects with prior information exhibited significant positive neural correlations with neural activity between the SMA and IPL. These results suggest that neural activity in these brain regions influence balancing ability and predictive factors. Prior knowledge of a postural perturbation’s timing could be a compensatory factor promoting the activation of predictive factors.
老年人的跌倒可能是由平衡障碍引起的,受到基于自我效能和结果预期的预测因素的影响。本研究调查了与区域神经功能活动相关的预测因素与姿势控制之间的关系。我们纳入了16名老年男性(平均年龄76.4±5.8岁),并分别使用日本版的迷你平衡评估系统测试(J-Mini-BESTest)和日本版的跌倒效能量表(JFES)评估了他们的平衡能力和跌倒相关的自我效能。我们在姿势紊乱之前、期间和之后进行了脑电图检查。使用特定感兴趣区域的电流密度分析右下顶叶(IPL)和辅助运动区(SMA)的皮层活动。足部反应值(FRV)用于评估姿势扰动期间的身体反应。姿势扰动后IPL中的神经活动值表明,当向参与者提供先前信息时,与JFES和J-Mini-BESTest评分呈显著正相关。姿势扰动前SMA的神经活动值与J-Mini-BESTest评分呈显著正相关,与FRV呈显著负相关。此外,在姿势扰动期间,具有先前信息的受试者在SMA和IPL之间表现出与神经活动显著的正相关。这些结果表明,这些大脑区域的神经活动会影响平衡能力和预测因素。先前对姿势扰动时间的了解可能是促进预测因素激活的补偿因素。
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引用次数: 0
Less Medicines in Older Patients in the Netherlands, The Lemon Study: Study Protocol of a Cluster Randomised Controlled Trial 荷兰老年患者少用药,柠檬研究:一项集群随机对照试验的研究方案
Pub Date : 2022-07-25 DOI: 10.26420/physmedrehabilint.2022.1201
Abou J, Elders Pjm, H. D, Domic J, Marum Rv, H. J.
Background and Objective: Overtreatment with cardiometabolic medication is a common phenomenon in older patients. Up to 20% of these patients may be eligible for deprescribing. Deprescribing may decrease the risk of adverse drug events and is indicated when a drug may lead to more harm than benefits. The LeMON study aims to develop, implement and evaluate a standardized template for the performance of clinical medication reviews (CMR) using evidence based tools and training to support deprescribing of cardiometabolic medication. Method: A clustered randomized controlled study involving twenty community pharmacists (CP). CP will be asked to conduct a CMR in ten patients. The intervention group will receive training on the background of deprescribing cardiometabolic medication and the use of tools and the control group will perform a CMR according to standard practice. Follow-up will take place within four weeks (T1) and after three months (T2) following the CMR. Patients 70 years or older; polypharmacy and chronic use of at least one blood pressure medicine and having a systolic blood pressure below 140 mmHg, or chronic use of glucose lowering medication and HbA1c level below 54 mmol/ mol were included. Discussion: The LeMON study will assess whether a primary care-based intervention educating CPs about deprescribing cardiometabolic medication reduces the number of cardiometabolic medication used by older patients with a blood pressure or HbA1c lower than the treatment targets tment. The use of algorithms including information on blood pressure and/or HbA1c and cardiometabolic medication use has not been studied previously.
背景与目的:心脏代谢药物过度治疗是老年患者的常见现象。这些患者中多达20%可能有资格取消描述。药物停用可以降低药物不良事件的风险,当一种药物可能弊大于利时,说明药物停用。LeMON研究旨在开发、实施和评估临床药物审查(CMR)绩效的标准化模板,使用基于证据的工具和培训来支持心脏代谢药物的描述。方法:20名社区药剂师参与的随机对照研究。CP将被要求对10名患者进行CMR。干预组将接受关于心脏代谢药物描述和工具使用的背景培训,对照组将根据标准实践进行CMR。随访将在CMR后四周(T1)和三个月(T2)内进行。70岁或以上的患者;包括多药治疗和慢性使用至少一种血压药物且收缩压低于140mmHg、或慢性使用降糖药物且HbA1c水平低于54mmol/mol。讨论:LeMON研究将评估以初级保健为基础的干预措施是否会减少血压或HbA1c低于治疗目标的老年患者使用的心脏代谢药物的数量。包括血压和/或HbA1c和心脏代谢药物使用信息在内的算法的使用以前没有进行过研究。
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引用次数: 0
The Importance of an Early Suppression of the Moro Reflex 早期抑制Moro反射的重要性
Pub Date : 2022-07-04 DOI: 10.26420/physmedrehabilint.2022.1200
Niklasson M, N. I.
The vestibular-Moro reflex connection was elaborated and it was concluded that a retained Moro reflex after the age of four months should be further investigated in order to prevent future sensorimotor difficulties.
详细阐述了前庭莫罗反射的联系,并得出结论,应进一步研究四个月大后保留的莫罗反射,以防止未来的感觉运动困难。
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引用次数: 0
Shortwave Diathermy: Actualization 短波透热:实现
Pub Date : 2022-05-04 DOI: 10.26420/physmedrehabilint.2022.1197
Sanchez Hm, M. Eg
Short wave diathermy (SWD) is a therapeutic modality that offers the body an increase in temperature, through the high frequency in electromagnetic irradiation, so as not to generate ionization to the tissues. This therapeutic modality works based on the principle that energy is transferred within the layers of deep tissues by a high frequency current and the generation of tissue heat. Therefore, there is an agitation of the molecules in response to an electric field, converting the kinetic energy into heat [1-4]. It uses radio frequency bands generally centered at 13.56MHz, 27.12MHz and 40.68MHz, with the most commonly used frequency being 27.12MHz with a corresponding wavelength of 11.6m (1.5).
短波透热(SWD)是一种治疗方式,通过高频电磁辐射为身体提供温度升高,以免对组织产生电离。这种治疗模式的工作原理是,通过高频电流和组织热的产生,能量在深层组织层内传递。因此,分子会因电场而搅动,将动能转化为热量[1-4]。它使用的无线电频带通常集中在13.56MHz、27.12MHz和40.68MHz,最常用的频率是27.12MHz,对应的波长为11.6m(1.5)。
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引用次数: 0
Reliability Comparisons of Cervical Active Range of Motion Measuring Methods: Universal Goniometer versus Virtual Reality 颈椎活动范围测量方法的可靠性比较:通用测角仪与虚拟现实
Pub Date : 2022-02-03 DOI: 10.26420/physmedrehabilint.2022.1195
C. P.
The purpose of this research study is to compare the reliability of measuring active cervical range of motion performed with the universal goniometer with an FDA approved XRHealth virtual reality computer program and the Oculus Rift. Methods: The design of the study is a single-blinded randomized controlled study. A sample size of 40 adults was recruited via email, posters, and person to person recruitment. The sample was comprised of males and females, ages 20 to 72-year-old. Equipment included a large universal goniometer with 12-inch arms and a covered full circle plastic body, oculus rift with a computer, VR Health System, chair with arms and a gait belt to control for trunk movements. All four investigators underwent a training session in the measurement of cervical range of motion utilizing a universal goniometer. Each participant was measured with each tool twice. Results: Virtual reality demonstrated a statistically significant difference from the standard goniometer methods at a 99% confidence level (p=0.01). Both tools (goniometer and virtual reality) were found to have good to excellent inter-rater reliability. Conclusion: This study suggests a virtual reality method can be used as a reliable clinical tool in comparison with the universal goniometric cervical active range of motion measurement. Recommendations for future studies should be focused on establishing the validity of virtual reality as an assessment tool using a larger sample size with a wide age range and those who have current cervical discomfort or are experiencing functional limitations in cervical ranges of motion.
本研究的目的是比较用通用测角仪、美国食品药品监督管理局批准的XRHealth虚拟现实计算机程序和Oculus Rift测量活动颈椎活动范围的可靠性。方法:本研究为单盲随机对照研究。通过电子邮件、海报和面对面招聘的方式招募了40名成年人。样本由20至72岁的男性和女性组成。设备包括一个带12英寸手臂和一个覆盖的圆形塑料身体的大型通用测角仪、带电脑的眼球裂孔、VR健康系统、带手臂的椅子和控制躯干运动的步态带。所有四名研究人员都接受了使用通用角度计测量颈椎活动范围的培训。每个参与者用每种工具测量两次。结果:在99%的置信水平下,虚拟现实与标准测角仪方法有统计学上的显著差异(p=0.01)。两种工具(测角仪和虚拟现实)都具有良好的评分者间可靠性。结论:本研究表明,虚拟现实方法可以作为一种可靠的临床工具,与通用角度测量颈椎活动范围相比较。未来研究的建议应侧重于确定虚拟现实作为一种评估工具的有效性,使用较大的样本量、较宽的年龄范围以及那些目前有宫颈不适或宫颈活动范围功能受限的人。
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引用次数: 0
期刊
Physical medicine and rehabilitation international
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