A Clark, R Zelmanovich, M R Hosseini Siyanaki, M Michel, C Hanna, C Davidson, B Lucke-Wold
The gut-brain axis plays an important role in bidirectional communication that exists and can be altered by injury. Neurotrauma provides acute alteration in the GI tract and alters autonomic function. In this focused review, we highlight what is known about GI disruption following neurotrauma. We then delve into how this affects recovery. Areas of innovation and emerging pre-clinical results are addressed. Finally, we address the link between neurotrauma induced GI dysfunction and progression to neurodegenerative disease states.
{"title":"Microbiome and Neurotrauma: Emerging Innovations.","authors":"A Clark, R Zelmanovich, M R Hosseini Siyanaki, M Michel, C Hanna, C Davidson, B Lucke-Wold","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The gut-brain axis plays an important role in bidirectional communication that exists and can be altered by injury. Neurotrauma provides acute alteration in the GI tract and alters autonomic function. In this focused review, we highlight what is known about GI disruption following neurotrauma. We then delve into how this affects recovery. Areas of innovation and emerging pre-clinical results are addressed. Finally, we address the link between neurotrauma induced GI dysfunction and progression to neurodegenerative disease states.</p>","PeriodicalId":91034,"journal":{"name":"Neurology & neurotherapy open access journal","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33444433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Clark, R. Zelmanovich, M. R. Hosseini Siyanaki, M. Michel, C. Hanna, C. Davidson, B. Lucke-Wold
The gut-brain axis plays an important role in bidirectional communication that exists and can be altered by injury. Neurotrauma provides acute alteration in the GI tract and alters autonomic function. In this focused review, we highlight what is known about GI disruption following neurotrauma. We then delve into how this affects recovery. Areas of innovation and emerging pre-clinical results are addressed. Finally, we address the link between neurotrauma induced GI dysfunction and progression to neurodegenerative disease states.
{"title":"Microbiome and Neurotrauma: Emerging Innovations.","authors":"A. Clark, R. Zelmanovich, M. R. Hosseini Siyanaki, M. Michel, C. Hanna, C. Davidson, B. Lucke-Wold","doi":"10.23880/nnoaj-16000170","DOIUrl":"https://doi.org/10.23880/nnoaj-16000170","url":null,"abstract":"The gut-brain axis plays an important role in bidirectional communication that exists and can be altered by injury. Neurotrauma provides acute alteration in the GI tract and alters autonomic function. In this focused review, we highlight what is known about GI disruption following neurotrauma. We then delve into how this affects recovery. Areas of innovation and emerging pre-clinical results are addressed. Finally, we address the link between neurotrauma induced GI dysfunction and progression to neurodegenerative disease states.","PeriodicalId":91034,"journal":{"name":"Neurology & neurotherapy open access journal","volume":"7 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68920609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
For centuries the lunar effects on human health and behaviour have been theorized; Association amongst vascular and psychiatric disorders, lunar phases was testified [1]. In the medical community it is commonly alleged that moon has some impact on the health of human beings [2]. Latest research suggests that there is a sign of association between the lunar cerebrovascular events and lunar phases. Studies show that haemorrhagic stroke, transient ischemic attack (TIA) and medically unexplained stroke symptoms had a complex occurrence throughout the full moon period [1]. Based mostly on circumstantial signs the waxing phase of moon is supposed to be linked with additional danger of impediments all through the surgery [3] also throughout the new moon period there is an augmented occurrence of intracranial aneurysm rupture [4].
{"title":"Moonstroke & MUSS","authors":"Divya R","doi":"10.23880/nnoaj-16000130","DOIUrl":"https://doi.org/10.23880/nnoaj-16000130","url":null,"abstract":"For centuries the lunar effects on human health and behaviour have been theorized; Association amongst vascular and psychiatric disorders, lunar phases was testified [1]. In the medical community it is commonly alleged that moon has some impact on the health of human beings [2]. Latest research suggests that there is a sign of association between the lunar cerebrovascular events and lunar phases. Studies show that haemorrhagic stroke, transient ischemic attack (TIA) and medically unexplained stroke symptoms had a complex occurrence throughout the full moon period [1]. Based mostly on circumstantial signs the waxing phase of moon is supposed to be linked with additional danger of impediments all through the surgery [3] also throughout the new moon period there is an augmented occurrence of intracranial aneurysm rupture [4].","PeriodicalId":91034,"journal":{"name":"Neurology & neurotherapy open access journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68920953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrograde Synaptic Transmitter of Endocannabinoid System - A Neuromodulatory Pathway","authors":"Rajajeyakumar M","doi":"10.23880/nnoaj-16000131","DOIUrl":"https://doi.org/10.23880/nnoaj-16000131","url":null,"abstract":"","PeriodicalId":91034,"journal":{"name":"Neurology & neurotherapy open access journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68920503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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