K. K. Mujeeb Rahman, G. Durgeshwar, P. Mohapatra, M. K. Panigrahi, Siladitya Mahanty
BACKGROUND Pulmonary embolism (PE) requires a high degree of clinical suspicion for its diagnosis and can mimic pneumonia due to its clinical, radiological, and laboratory findings. Co-existence of PE and pneumonia can also occur, which is surprisingly more common than appreciated. CASE SUMMARY Here, we report a case of a young male who initially presented during the peak of the coronavirus disease 2019 pandemic with features of pneumonia. He was kept under observation and was later diagnosed and treated for a right main pulmonary artery embolism without any identifiable source of thrombosis. CONCLUSION PE and pneumonia share common clinical, radiological, and laboratory findings that may delay the diagnosis of PE. Hypoxia disproportionate to the extent of radiological involvement could be an indicator of an underlying PE.
背景 肺栓塞（PE）的诊断需要临床高度怀疑，并且由于其临床、放射学和实验室检查结果可能与肺炎相似。肺栓塞与肺炎并存的情况也可能发生，但其常见程度却出乎意料。病例摘要 在此，我们报告了一例年轻男性病例，他最初在 2019 年冠状病毒疾病大流行高峰期出现肺炎症状。他一直处于观察状态，后来被诊断为右主肺动脉栓塞并接受了治疗，但未发现任何可识别的血栓来源。结论 PE 和肺炎有共同的临床、放射学和实验室检查结果，可能会延误 PE 的诊断。与放射学受累程度不相称的缺氧可能是潜在 PE 的一个指标。
{"title":"Pulmonary infarct masquerading as community-acquired pneumonia in the COVID-19 scenario: A case report","authors":"K. K. Mujeeb Rahman, G. Durgeshwar, P. Mohapatra, M. K. Panigrahi, Siladitya Mahanty","doi":"10.5320/wjr.v13.i1.1","DOIUrl":"https://doi.org/10.5320/wjr.v13.i1.1","url":null,"abstract":"BACKGROUND\u0000 Pulmonary embolism (PE) requires a high degree of clinical suspicion for its diagnosis and can mimic pneumonia due to its clinical, radiological, and laboratory findings. Co-existence of PE and pneumonia can also occur, which is surprisingly more common than appreciated.\u0000 CASE SUMMARY\u0000 Here, we report a case of a young male who initially presented during the peak of the coronavirus disease 2019 pandemic with features of pneumonia. He was kept under observation and was later diagnosed and treated for a right main pulmonary artery embolism without any identifiable source of thrombosis.\u0000 CONCLUSION\u0000 PE and pneumonia share common clinical, radiological, and laboratory findings that may delay the diagnosis of PE. Hypoxia disproportionate to the extent of radiological involvement could be an indicator of an underlying PE.","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":"119 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140493846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary arterial hypertension confirmed by right heart catheterization following COVID-19 pneumonia: A case report and review of literature","authors":"M. Henriques King, I. Ogbuka, V. Bond","doi":"10.5320/wjr.v12.i1.10","DOIUrl":"https://doi.org/10.5320/wjr.v12.i1.10","url":null,"abstract":"","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49480879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monoclonal antibody for COVID-19: Unveiling the recipe of a new cocktail","authors":"JyotiVyas Bajpai, S. Kant, A. Verma, A. Pradhan","doi":"10.5320/wjr.v12.i1.1","DOIUrl":"https://doi.org/10.5320/wjr.v12.i1.1","url":null,"abstract":"","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42658853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Hannun, Walter Hannun, Hugo Hyung Yoo, L. Resende
Like father, like son: Pulmonary thromboembolism due to inflammatory or hereditary condition? Two case reports
有其父必有其子：炎症或遗传性疾病引起的肺血栓栓塞？两份病例报告
{"title":"Like father, like son: Pulmonary thromboembolism due to inflammatory or hereditary condition? Two case reports","authors":"P. Hannun, Walter Hannun, Hugo Hyung Yoo, L. Resende","doi":"10.5320/wjr.v11.i1.12","DOIUrl":"https://doi.org/10.5320/wjr.v11.i1.12","url":null,"abstract":"Like father, like son: Pulmonary thromboembolism due to inflammatory or hereditary condition? Two case reports","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41974155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SARS-CoV-2 with concurrent coccidioidomycosis complicated by refractory pneumothorax in a Hispanic male: A case report and literature review
一例西班牙裔男性严重急性呼吸系统综合征冠状病毒2型并发球虫病并发难治性肺气肿的病例报告和文献复习
{"title":"SARS-CoV-2 with concurrent coccidioidomycosis complicated by refractory pneumothorax in a Hispanic male: A case report and literature review","authors":"Joscilin Mathew, S. Cherukuri, F. Dihowm","doi":"10.5320/wjr.v11.i1.1","DOIUrl":"https://doi.org/10.5320/wjr.v11.i1.1","url":null,"abstract":"SARS-CoV-2 with concurrent coccidioidomycosis complicated by refractory pneumothorax in a Hispanic male: A case report and literature review","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41500519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
COPD is one of the leading causes of mortality and morbidity worldwide. One of the most important features of this disease is exacerbations where a patient’s respiratory symptoms episodically worsen. Exacerbations accounted for over 140,000 hospital admissions in 2012 in the UK with considerably more exacerbations being treated in primary care. Despite significant research in this area in recent years, treatment of acute exacerbations in the community remains limited to oral glucocorticoids, antibiotics and bronchodilators. One of the issues with unpicking the complexity of exacerbations is trying to find out the exact underlying cause and mechanism that leads to symptoms and lung destruction. Currently symptoms are initially guided by symptoms alone though multiple causes of exacerbations have common presentations. This includes viral and bacterial infections and episodes relating to environmental triggers such as pollen and pollution. There is also evidence that cardiovascular factors can contribute to symptoms of breathlessness that can mimic COPD exacerbations. In this editorial we discuss recent advances in the use of precision medicine to more accurately treat exacerbations of COPD. This includes identification of phenotypes that could help
{"title":"Personalising exacerbation prediction strategies in chronic obstructive pulmonary disease","authors":"P. Ellis, A. Turner","doi":"10.5320/wjr.v10.i2.11","DOIUrl":"https://doi.org/10.5320/wjr.v10.i2.11","url":null,"abstract":"COPD is one of the leading causes of mortality and morbidity worldwide. One of the most important features of this disease is exacerbations where a patient’s respiratory symptoms episodically worsen. Exacerbations accounted for over 140,000 hospital admissions in 2012 in the UK with considerably more exacerbations being treated in primary care. Despite significant research in this area in recent years, treatment of acute exacerbations in the community remains limited to oral glucocorticoids, antibiotics and bronchodilators. One of the issues with unpicking the complexity of exacerbations is trying to find out the exact underlying cause and mechanism that leads to symptoms and lung destruction. Currently symptoms are initially guided by symptoms alone though multiple causes of exacerbations have common presentations. This includes viral and bacterial infections and episodes relating to environmental triggers such as pollen and pollution. There is also evidence that cardiovascular factors can contribute to symptoms of breathlessness that can mimic COPD exacerbations. In this editorial we discuss recent advances in the use of precision medicine to more accurately treat exacerbations of COPD. This includes identification of phenotypes that could help","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44061337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis and treatment of subsegmental pulmonary embolism","authors":"M. Newnham, A. Turner","doi":"10.5320/WJR.V9.I3.30","DOIUrl":"https://doi.org/10.5320/WJR.V9.I3.30","url":null,"abstract":"","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48914484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Yamaguchi, T. Tsuji, K. Aoshiba, Hiroyuki Nakamura, S. Abe
Many problems regarding structure-function relationships have remained unsolved in the field of respiratory physiology. In the present review, we highlighted these uncertain issues from a variety of anatomical and physiological viewpoints. Model A of Weibel in which dichotomously branching airways are incorporated should be used for analyzing gas mixing in conducting and acinar airways. Acinus of Loeschcke is taken as an anatomical gas-exchange unit. Although it is difficult to define functional gas-exchange unit in a way entirely consistent with anatomical structures, acinus of Aschoff may serve as a functional gas-exchange unit in a first approximation. Based on anatomical and physiological perspectives, the multiple inert-gas elimination technique is thought to be highly effective for predicting ventilation-perfusion heterogeneity between acini of Aschoff under steady-state condition. Changes in effective alveolar PO2, the most important parameter in classical gas-exchange theory, are coherent with those in mixed alveolar PO2 decided from the multiple inert-gas elimination technique. Therefore, effective alveolar-arterial PO2 difference is considered useful for assessing gas-exchange abnormalities in lung periphery. However, one should be aware that although alveolar-arterial PO2 difference sensitively detects moderately low ventilation-perfusion regions causing hypoxemia, it is insensitive to abnormal gas exchange evoked by very low and high ventilation-perfusion regions. Pulmonary diffusing capacity for CO (DLCO) and the value corrected for alveolar volume (VAV), i.e. DLCO/VAV (KCO), are thought to be crucial for diagnosing alveolar-wall damages. DLCO-related parameters have higher sensitivity to detecting abnormalities in pulmonary microcirculation than those in the alveolocapillary membrane. We would like to recommend four categories derived from combining behaviors of DLCO with those of KCO for differential diagnosis on anatomically morbid states in alveolar walls: type-1 abnormality defined by decrease in both DLCO and KCO; type-2 abnormality by decrease in DLCO but increase in KCO; type-3 abnormality by decrease in DLCO but restricted rise in KCO; and type-4 abnormality by increase in both DLCO and KCO.
{"title":"Anatomical backgrounds on gas exchange parameters in the lung","authors":"K. Yamaguchi, T. Tsuji, K. Aoshiba, Hiroyuki Nakamura, S. Abe","doi":"10.5320/WJR.V9.I2.8","DOIUrl":"https://doi.org/10.5320/WJR.V9.I2.8","url":null,"abstract":"Many problems regarding structure-function relationships have remained unsolved in the field of respiratory physiology. In the present review, we highlighted these uncertain issues from a variety of anatomical and physiological viewpoints. Model A of Weibel in which dichotomously branching airways are incorporated should be used for analyzing gas mixing in conducting and acinar airways. Acinus of Loeschcke is taken as an anatomical gas-exchange unit. Although it is difficult to define functional gas-exchange unit in a way entirely consistent with anatomical structures, acinus of Aschoff may serve as a functional gas-exchange unit in a first approximation. Based on anatomical and physiological perspectives, the multiple inert-gas elimination technique is thought to be highly effective for predicting ventilation-perfusion heterogeneity between acini of Aschoff under steady-state condition. Changes in effective alveolar PO2, the most important parameter in classical gas-exchange theory, are coherent with those in mixed alveolar PO2 decided from the multiple inert-gas elimination technique. Therefore, effective alveolar-arterial PO2 difference is considered useful for assessing gas-exchange abnormalities in lung periphery. However, one should be aware that although alveolar-arterial PO2 difference sensitively detects moderately low ventilation-perfusion regions causing hypoxemia, it is insensitive to abnormal gas exchange evoked by very low and high ventilation-perfusion regions. Pulmonary diffusing capacity for CO (DLCO) and the value corrected for alveolar volume (VAV), i.e. DLCO/VAV (KCO), are thought to be crucial for diagnosing alveolar-wall damages. DLCO-related parameters have higher sensitivity to detecting abnormalities in pulmonary microcirculation than those in the alveolocapillary membrane. We would like to recommend four categories derived from combining behaviors of DLCO with those of KCO for differential diagnosis on anatomically morbid states in alveolar walls: type-1 abnormality defined by decrease in both DLCO and KCO; type-2 abnormality by decrease in DLCO but increase in KCO; type-3 abnormality by decrease in DLCO but restricted rise in KCO; and type-4 abnormality by increase in both DLCO and KCO.","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47897650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of central sleep apnea in patients with heart failure: Now and future","authors":"A. Murata, T. Kasai","doi":"10.5320/WJR.V9.I1.1","DOIUrl":"https://doi.org/10.5320/WJR.V9.I1.1","url":null,"abstract":"","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42343783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Classical regression equations of spirometric parameters are not applicable for diagnosing spirometric abnormalities in adipotic adults
肺活量参数的经典回归方程不适用于诊断肥胖成年人的肺活量异常
{"title":"Classical regression equations of spirometric parameters are not applicable for diagnosing spirometric abnormalities in adipotic adults","authors":"K. Yamaguchi, H. Omori, T. Tsuji, K. Aoshiba","doi":"10.5320/WJR.V8.I1.1","DOIUrl":"https://doi.org/10.5320/WJR.V8.I1.1","url":null,"abstract":"Classical regression equations of spirometric parameters are not applicable for diagnosing spirometric abnormalities in adipotic adults","PeriodicalId":91425,"journal":{"name":"World journal of respirology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45356473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：