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Segmental Classification of the Internal Carotid Artery: An Overview 颈内动脉的节段分类:综述
Pub Date : 2020-12-30 DOI: 10.1097/01.cne.0000734828.08438.5f
S. Bonasia, A. Bouthillier, T. Robert
arteries in humans, as it interests a diverse group of physicians: ear, nose, and throat specialists; neuroradiologists; neurologists; anatomists; and neurosurgeons. During the past century, many classifications of the ICA segmental division have been proposed, with the purpose to be helpful during clinical practice. Because each specialist who treats pathologies of or around the ICA needs different details, a universally shared classification is difficult to propose. Historically, the classifications that spread the most had some important characteristics: simplicity, easy to use, easy to remember, and reproducibility. In this overview, we present the most used classifications of the ICA with their respective clinical implications, pros and cons, to help the reader to orientate and to choose the most helpful classification in his clinical practice.
人类的动脉,因为它引起了不同医生群体的兴趣:耳鼻喉专家;神经放射科医生;神经学家;解剖学家;和神经外科医生。在过去的一个世纪里,人们提出了许多ICA节段划分的分类,目的是对临床实践有所帮助。由于每一位治疗ICA或其周围病变的专家都需要不同的细节,因此很难提出一个普遍共享的分类。从历史上看,传播最广的分类具有一些重要特征:简单、易于使用、易于记忆和可重复性。在这篇综述中,我们介绍了ICA最常用的分类及其各自的临床意义、优缺点,以帮助读者在临床实践中定位和选择最有用的分类。
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引用次数: 0
Embryologic Development of the Normal Craniofacial Arterial System: Part 1 正常颅面动脉系统的胚胎发育:第一部分
Pub Date : 2020-11-15 DOI: 10.1097/01.cne.0000734696.04124.b8
Lorenzo Bertulli, T. Robert
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引用次数: 0
Decompressive Craniectomy in Management of Severe Traumatic Brain Injury 重型外伤性脑损伤的减压术治疗
Pub Date : 2020-10-30 DOI: 10.1097/01.CNE.0000732592.98360.44
Kevin G. Kwan, R. C. Pena, J. Ullman
problem, with an estimated 27 million cases per year leading to subsequent hospitalization and possible mortality. Decompressive craniectomy (DC), the surgical removal of a portion of the skull with exposure of the dura mater, has long been used for the treatment of severe TBI as an established means of decreasing mortality. In a comparison of the 2 largest randomized clinical trials (RCTs) evaluating the efficacy of DC versus medical management for refractory intracranial pressures (rICPs) (DECRA 2011 vs RESCUEicp 2016 trials), one revealed no significant impact on surgically treated patient mortality, whereas the other demonstrated a clear reduction of patient fatality in the surgically treated arm, but at the expense of creating a larger cohort of survivors with severe incapacitation, at least in the short term. Although DC has remained a standard treatment of acute subdural hematoma (ASDH), it is only now being compared in a large RCT (RESCUE-ASDH) to emergent craniotomy, another widely accepted procedure. Such results demonstrate the persistence of clinical equipoise when determining the utility of DC versus medical management or craniotomy for patients with severe TBI resulting in rICPs. In this article, we review the indications, pathophysiology, surgical technique, complications, controversy, and ethical considerations involving DC.
据估计,每年有2700万例病例导致随后的住院治疗和可能的死亡。减压颅骨切除术(DC)是指在暴露硬脑膜的情况下切除部分颅骨,长期以来一直被用于治疗严重的TBI,作为降低死亡率的既定手段。在评估DC与药物治疗对难治性颅内压(rICPs)疗效的两项最大的随机临床试验(RCT)的比较中(DECRA 2011与RESCUEicp 2016试验),一项试验显示对手术治疗的患者死亡率没有显著影响,而另一项试验则显示手术治疗的手臂的患者死亡率明显降低,但至少在短期内,这是以创造更多严重丧失能力的幸存者为代价的。尽管DC仍然是急性硬膜下血肿(ASDH)的标准治疗方法,但它现在才在大型随机对照试验(RESCUE-ASDH)中与另一种广泛接受的紧急开颅手术进行比较。这些结果表明,在确定DC与医疗管理或开颅术对导致rICP的严重TBI患者的效用时,临床平衡的持久性。在这篇文章中,我们回顾了DC的适应症、病理生理学、手术技术、并发症、争议和伦理考虑。
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引用次数: 0
Symptomatic Mild Carotid Artery Stenosis 症状性轻度颈动脉狭窄
Pub Date : 2020-09-30 DOI: 10.1097/01.cne.0000723688.52449.d5
A. Larson, V. Nardi, G. Lanzino, W. Brinjikji, E. Scharf, L. Savastano
predict the risk of future ischemic events in patients with carotid artery stenosis based on ultrasound findings that assessed morphology and composition of plaque. However, with publication of landmark clinical trials, leading to a definition of the indications for treatment of symptomatic and asymptomatic patients, the focus was exclusively on the degree of stenosis rather than plaque morphology and composition. Therefore, over the past 30 years, decisions for invasive treatment have been based on degree of stenosis, and this is reflected in published guidelines. However, a growing body of scientific evidence suggests that a culprit plaque is not necessarily large and causing “clinically significant stenosis,” but vulnerable (ie, prone to rupture or to develop ulcers and erosions) and thrombogenic—leading to sudden occlusion, emboli, and subclinical microemboli with the potential to recur over time. The bulk of this research, which was mostly in the coronary arteries, has led to a broad awareness in the cardiology community of the importance of plaque morphology and composition, in addition to the degree of stenosis, in influencing the risk of future ischemic events. The concept of “unstable” plaque, independent from the degree of stenosis, has been the basis for intensive research in high-resolution intravascular imaging platforms and aggressive therapeutic measures. More recently, advances in noninvasive imaging that improved visualization of plaque features such as hemorrhage, and a better understanding of the mechanism leading to thromboembolic events, have raised awareness within the stroke community about the concept of “vulnerable carotid plaque.” This has led to the identification of patients with mildly stenotic but vulnerable plaque and whose cases would otherwise have been diagnosed as strokes of “undetermined source.” In this article, we briefly summarize pathologic, imaging, and clinical criteria of unstable plaque in patients with mild carotid artery stenosis, with case examples.
根据评估斑块形态和成分的超声检查结果,预测颈动脉狭窄患者未来发生缺血性事件的风险。然而,随着具有里程碑意义的临床试验的发表,有症状和无症状患者的治疗适应症得到了定义,重点只放在狭窄程度上,而不是斑块的形态和成分上。因此,在过去的30年里,侵入性治疗的决定都是基于狭窄程度,这反映在已发布的指南中。然而,越来越多的科学证据表明,罪魁祸首斑块不一定很大,会导致“临床上显著的狭窄”,而是很脆弱(即容易破裂或发展为溃疡和侵蚀)和血栓形成——导致突然闭塞、栓塞和亚临床微栓子,并有可能随着时间的推移复发。这项研究主要针对冠状动脉,使心脏病学界广泛认识到斑块形态和成分以及狭窄程度在影响未来缺血性事件风险方面的重要性。“不稳定”斑块的概念与狭窄程度无关,是高分辨率血管内成像平台和积极治疗措施深入研究的基础。最近,非侵入性成像的进展改善了斑块特征(如出血)的可视化,并更好地了解了导致血栓栓塞事件的机制,提高了中风社区对“易受感染颈动脉斑块”概念的认识。这导致了轻度狭窄但易受感染斑块的患者的识别,否则其病例将被诊断为“来源不明”的中风。在这篇文章中,我们简要总结了轻度颈动脉狭窄患者不稳定斑块的病理、影像学和临床标准,并附例。
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引用次数: 0
Anatomic Triangles of the Jugular Foramen Region 颈Foramen区的解剖三角形
Pub Date : 2020-09-15 DOI: 10.1097/01.cne.0000721436.97052.8b
Jaafar Basma, J. Robertson, L. Michael
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引用次数: 0
Nerve Transfers for Upper Extremity Reanimation in Tetraplegia: Part II—Reinnervation Strategies and Clinical Outcomes 四肢瘫痪患者上肢神经再支配的神经移植:第二部分——再支配策略和临床效果
Pub Date : 2020-08-30 DOI: 10.1097/01.CNE.0000698200.67605.46
J. Khalifeh, Christopher F. Dibble, C. Dy, M. Boyer, W. Z. Ray
The operative strategy for nerve transfer in tetraplegia is tailored to the individual patient’s functional deficits and reinnervation goals. Information obtained from the history, physical examination, and electrodiagnostic studies permits the development of a strategy for nerve transfer based on the level of injury, a patient’s reinnervation priorities for functional recovery, and the available donor and recipient nerve pairings for transfer (Table 1). The operative techniques for nerve transfers to restore thumb and finger flexion, thumb and finger extension, and elbow extension have previously been reported. Descriptions of the surgical technique are located within the suggested readings. The objective of Part II in the current 2-part review article is to present results for the various reinnervation strategies and to suggest areas for future research in targeting upper extremity neurorestoration in tetraplegia.
四肢瘫痪患者的神经转移手术策略是针对个别患者的功能缺陷和神经再支配目标而制定的。从病史、体格检查和电诊断研究中获得的信息允许根据损伤程度、患者功能恢复的神经再支配优先级以及可用于转移的供体和受体神经配对制定神经转移策略(表1)。神经转移恢复拇指和手指屈曲、拇指和手指伸展以及肘部伸展的手术技术以前已有报道。手术技术的说明位于建议的读数范围内。目前这篇由两部分组成的综述文章的第二部分的目的是介绍各种神经再支配策略的结果,并提出未来针对四肢瘫痪患者上肢神经修复的研究领域。
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引用次数: 0
Nerve Transfers for Upper Extremity Reanimation in Tetraplegia: Part I—Background and Operative Considerations 神经移植用于四肢瘫痪患者上肢再活动:第一部分——背景和手术注意事项
Pub Date : 2020-07-30 DOI: 10.1097/01.CNE.0000696344.86241.50
J. Khalifeh, Christopher F. Dibble, C. Dy, M. Boyer, W. Z. Ray
Traumatic spinal cord injury (SCI) leads to chronic impairment and disability. In the United States, the annual incidence of SCI is estimated as 54 cases per 1 million population, with a prevalence of greater than 250,000 persons currently living with the condition. Greater than 50% of SCIs occur in the cervical segments of the spinal cord, which can result in tetraplegia. Depending on the severity and level of injury, SCI may lead to varying degrees of motor and sensory loss in the neck, trunk, and upper and lower extremities. As recovery from a complete SCI is exceedingly rare, affected patients are left with permanent disability requiring lifelong medical care and rehabilitation. Patients with tetraplegia experience significant limitations in their mobility, ability to self-care, and participation restrictions in their education, employment, social relationships, and community engagement. They are often dependent on residual motor function and the assistance of caregivers to complete their activities of daily living. A survey of patients with tetraplegia indicated that regaining arm and hand function is rated as the highest priority, above autonomic functions of the bowel and bladder, walking ability, sexual function, and pain control. Therefore, therapeutic interventions that target functional recovery of the upper extremity have a significant impact on independence and quality of life. Operative reconstruction of the upper extremity in tetraplegia involves stand-alone or combined approaches using nerve transfers, tendon transfers, tenodeses, and/or joint stabilizations. The goal of surgery is improved strength and usability of the arm and hand, and occasionally reduction of muscle instability, pain with spasticity, or joint contractures. Tendon transfers have an established role as the mainstay approach to restore critical hand movements in
创伤性脊髓损伤(SCI)会导致慢性损伤和残疾。在美国,SCI的年发病率估计为每100万人口54例,目前患病率超过25万。超过50%的SCIs发生在脊髓的颈段,这可能导致四肢瘫痪。根据损伤的严重程度和程度,SCI可能导致颈部、躯干、上下肢不同程度的运动和感觉丧失。由于完全性脊髓损伤的康复极为罕见,受影响的患者会留下永久性残疾,需要终身医疗护理和康复。四肢瘫痪患者在行动能力、自我护理能力以及参与教育、就业、社会关系和社区参与方面都受到严重限制。他们往往依赖剩余的运动功能和照顾者的帮助来完成日常生活活动。一项对四肢瘫痪患者的调查表明,恢复手臂和手部功能被列为最高优先级,高于肠道和膀胱的自主功能、行走能力、性功能和疼痛控制。因此,针对上肢功能恢复的治疗干预措施对独立性和生活质量有重大影响。四肢瘫痪患者上肢的手术重建包括使用神经转移、肌腱转移、肌腱固定和/或关节稳定的单独或联合方法。手术的目的是提高手臂和手的力量和可用性,偶尔减少肌肉不稳定、痉挛性疼痛或关节挛缩。肌腱转移作为恢复关键手部动作的主要方法,在
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引用次数: 0
Unruptured Arteriovenous Malformations: Natural History and Management 未破裂动静脉畸形的自然史与治疗
Pub Date : 2020-07-15 DOI: 10.1097/01.CNE.0000695876.49151.d3
R. Bram, S. Amin‐Hanjani
flow vascular abnormalities characterized by intertwined feeding arteries and draining veins with no intervening capillary network. Rudolph Virchow is credited with first describing cerebral AVMs in 1863 when he defined and differentiated several intracranial vascular pathologic entities. In 1928, Walter Dandy reported 8 cases and Harvey Cushing along with Percival Bailey described treatment of 16 AVMs with catastrophic results. At that time, Cushing was quoted as stating that surgical excision of an AVM was unthinkable because of significant risk of hemorrhage. These cerebrovascular lesions represent some of the most complex pathology within the scope of neurosurgery. Their management has significantly evolved over the past century and has garnered significant attention in the neurosurgical community. The serious consequences of an AVM-related intracerebral hemorrhage (ICH) combined with the pivotal role of the neurosurgeon in the multidisciplinary treatment of AVMs make this topic of importance to the practicing neurosurgeon. This review summarizes the epidemiology, natural history, and multimodality treatment of patients with unruptured AVMs.
流动性血管异常,其特征是供血动脉和引流静脉交织在一起,没有介入的毛细血管网。Rudolph Virchow于1863年首次描述了脑动静脉畸形,当时他定义并区分了几种颅内血管病理实体。1928年,Walter Dandy报告了8例病例,Harvey Cushing和Percival Bailey描述了16例AVM的治疗,结果是灾难性的。当时引用库欣的话说,动静脉畸形的手术切除是不可想象的,因为出血的风险很大。这些脑血管病变代表了神经外科范围内最复杂的病理学。他们的管理在过去的一个世纪里发生了重大变化,并在神经外科界引起了极大的关注。AVM相关脑出血(ICH)的严重后果,加上神经外科医生在AVM多学科治疗中的关键作用,使这一主题对执业神经外科医生具有重要意义。本文综述了未破裂动静脉畸形患者的流行病学、自然史和多模式治疗。
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引用次数: 0
Postoperative Dysphagia After Anterior Cervical Spinal Surgery 颈椎前路手术后吞咽困难
Pub Date : 2020-07-01 DOI: 10.1097/01.CNE.0000852676.65464.64
Peter F. Helvie, T. Jenkins, Brett D. Rosenthal, Alpesh A. Patel
patients after anterior cervical discectomy and fusion (ACDF). The reported incidence varies significantly, from as little as 3% to as high as 83%. The variability is thought to be from a lack of consensus on diagnostic criteria, screening, and expected outcomes. Fortunately, dysphagia after anterior cervical spine surgery is typically mild and transient. However, chronic dysphagia can prove to be a significant health burden on patients. Many factors are hypothesized as potential causes for dysphagia after an ACDF. Multiple patient risk factors and variations in surgical technique have been associated with increased rates of postoperative dysphagia. In addition, consensus for how to measure dysphagia clinically has not been well established. A more standardized method of studying dysphagia will be important for future studies to better understand this common and multifaceted problem established in anterior cervical spine surgery. Dysphagia is a common postoperative condition with which all spine surgeons should be familiar. This review will help educate the clinician on the possible causes of dysphagia, as well as patient and surgical characteristics that can help the surgeon counsel and potentially prevent postoperative dysphagia.
颈椎前路椎间盘切除术和融合(ACDF)后的患者。报告的发病率差异很大,低至3%,高至83%。这种差异被认为是由于对诊断标准、筛查和预期结果缺乏共识。幸运的是,颈椎前路手术后的吞咽困难通常是轻微和短暂的。然而,慢性吞咽困难可被证明是患者的重大健康负担。许多因素被假设为ACDF后吞咽困难的潜在原因。多种患者危险因素和手术技术的变化与术后吞咽困难的发生率增加有关。此外,如何在临床上测量吞咽困难尚未形成共识。一种更加标准化的研究吞咽困难的方法对未来的研究很重要,可以更好地理解颈椎前路手术中常见的、多方面的问题。吞咽困难是一种常见的术后症状,所有脊柱外科医生都应该熟悉。这篇综述将帮助临床医生了解吞咽困难的可能原因,以及患者和手术特征,这些特征可以帮助外科医生提出建议并潜在地预防术后吞咽困难。
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引用次数: 0
Middle Meningeal Artery Embolization for Chronic Subdural Hematoma: Rationale, Technique, and Results 脑膜中动脉栓塞治疗慢性硬膜下血肿:原理、技术和结果
Pub Date : 2020-06-30 DOI: 10.1097/01.CNE.0000695020.96579.55
A. Larson, L. Savastano, S. Rammos, W. Brinjikji
rosurgical condition that has a poor natural history. With an inhospital mortality of 16.7%, 1-year mortality of 32%, and only 21.1% of admitted patients returning home, cSDH remains a disabling and deadly disease. The incidence of cSDH greatly increases with age, with some estimates being as high as 18 per 100,000 individuals between the ages of 71 and 80 years. With an aging population and increased use of antiplatelet and anticoagulation medications, the incidence of cSDH is expected to exceed 60,000 new cases per year by the year 2030. Management strategies for cSDH vary widely and are subject to provider and institutional preferences. Traditional management avenues for cSDH have involved conservative management and open surgery. Conservative management has included observation, the use of corticosteroids, statins, osmotically active agents, platelet-activating factor inhibitors, and plasminogen activator inhibitors. Statins, in particular, have been demonstrated to be beneficial for patients with cSDH in recent randomized clinical trials. Surgical management includes options such as twist drill craniostomy at the bedside and open surgical drainage via burr holes or formal craniotomy. In a randomized clinical trial performed in 2009, the use of drains after burr hole drainage was associated with reduced recurrence and mortality at 6 months, thereby justifying the use of drains after burr hole drainage of cSDH. In general, patients who are asymptomatic or have minor symptoms with smaller hematoma volumes typically warrant conservative management, whereas patients with more severe symptoms and larger hematoma volumes require operative intervention. The success rate of each method in resolving the hematoma is variable, although surgical intervention is generally favorable in this regard and offers the advantage of an immediate decompressive effect. However, the recurrence rate of cSDH even after surgical evacuation is variable and may be as high as 37% by some estimates.
有不良自然病史的神经外科疾病。cSDH的住院死亡率为16.7%,1年死亡率为32%,只有21.1%的入院患者回家,它仍然是一种致残和致命的疾病。cSDH的发病率随着年龄的增长而大大增加,一些估计在71岁至80岁之间高达十万分之十八。随着人口老龄化以及抗血小板和抗凝药物使用的增加,预计到2030年,cSDH的发病率将超过每年60000例。cSDH的管理策略差异很大,并取决于提供商和机构的偏好。cSDH的传统管理途径包括保守管理和开放手术。保守治疗包括观察、使用皮质类固醇、他汀类药物、渗透活性剂、血小板活化因子抑制剂和纤溶酶原激活剂抑制剂。在最近的随机临床试验中,他汀类药物尤其被证明对cSDH患者有益。手术管理包括在床边进行麻花钻开颅术,以及通过毛刺孔或正式开颅术进行开放式手术引流。在2009年进行的一项随机临床试验中,毛刺孔引流术后使用引流管可降低6个月时的复发率和死亡率,从而证明在cSDH的毛刺孔引流后使用引流器是合理的。一般来说,无症状或症状轻微、血肿体积较小的患者通常需要保守治疗,而症状更严重、血肿体积较大的患者则需要手术干预。每种方法解决血肿的成功率各不相同,尽管手术干预在这方面通常是有利的,并且具有立即减压的优点。然而,即使在手术后,cSDH的复发率也是可变的,据估计可能高达37%。
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引用次数: 3
期刊
Contemporary neurosurgery
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