Nanoscience and nanoengineering最新文献

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Investigation of the Formation of Nanofilms on the Substrates of Porous Aluminum Oxide 多孔氧化铝基板上纳米膜形成的研究

Nanoscience and nanoengineering

Pub Date : 2018-12-17 DOI: 10.1201/9781351138789-9

A. V. Vakhrushev, A. Y. Fedotov, A. V. Severyukhin, R. Valeev

引用次数: 0

Combination of Sonodynamic and Photodynamic Therapy against Cancer Would Be Effective through Using a Regulated Size of Nanoparticles. 通过使用大小可调的纳米粒子，声动力疗法和光动力疗法联合治疗癌症将非常有效。

Nanoscience and nanoengineering

Pub Date : 2016-02-01 DOI: 10.13189/nn.2016.040101

N Miyoshi, S K Kundu, T Tuziuti, K Yasui, I Shimada, Y Ito

Nanoparticles have been used for many functional materials in nano-sciences and photo-catalyzing surface chemistry. The titanium oxide nanoparticles will be useful for the treatment of tumor by laser and/or ultrasound as the sensitizers in nano-medicine. We have studied the combination therapy of photo- and sono-dynamic therapies in an animal tumor model. Oral-administration of two sensitizers titanium oxide, 0.2%-TiO₂ nanoparticles for sono-dynamic and 1 mM 5-aminolevulinic acid for photodynamic therapies have resulted in the best combination therapeutic effects for the cancer treatment. Our light microscopic and Raman spectroscopic studies revealed that the titanium nanoparticles were distributed inside the blood vessel of the cancer tissue (1-3 μm sizes). Among these nanoparticles with a broad size distribution, only particular-sized particles could penetrate through the blood vessel of the cancer tissue, while other particles may only exhibit the side effects in the model mouse. Therefore, it may be necessary to separate the optimum size particles. For this purpose we have separated TiO₂ nanoparticles by countercurrent chromatography with a flat coiled column (1.6 mm ID) immersed in an ultrasonic bath (42 KHz). Separation was performed with a two-phase solvent system composed of 1-butanol-acetic acid-water at a volume ratio of 4:1:5 at a flow rate of 0.1 ml/min. Countercurrent chromatographic separation yielded fractions containing particle aggregates at 31 and 4400 nm in diameter.

纳米粒子已被用于纳米科学和光催化表面化学中的许多功能材料。氧化钛纳米粒子作为纳米医学中的敏化剂，可用于激光和/或超声波治疗肿瘤。我们在动物肿瘤模型中研究了光动力疗法和超声动力疗法的联合疗法。口服两种敏化剂氧化钛（0.2%-TiO2 纳米颗粒用于声动力疗法，1 mM 5-aminolevulinic acid 用于光动力疗法）对癌症治疗产生了最佳的联合治疗效果。我们的光镜和拉曼光谱研究显示，钛纳米粒子分布在癌组织的血管内（大小为 1-3 μm）。在这些大小分布广泛的纳米粒子中，只有特定大小的粒子可以穿透癌症组织的血管，而其他粒子可能只对模型小鼠产生副作用。因此，可能有必要分离出最佳尺寸的粒子。为此，我们采用逆流色谱法分离 TiO2 纳米粒子，使用的是浸在超声波浴（42 千赫）中的扁平卷曲柱（内径 1.6 毫米）。分离采用 1-丁醇-乙酸-水两相溶剂系统，体积比为 4:1:5，流速为 0.1 ml/min。逆流色谱分离得到的馏分含有直径分别为 31 纳米和 4400 纳米的颗粒聚集体。

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引用次数: 0

Fabrication of Dye Sensitized Solar Cell Using Nanocrystalline TiO2 and Optical Characterization of Photo-Anode 纳米TiO2染料敏化太阳能电池的制备及光阳极的光学表征

Nanoscience and nanoengineering

Pub Date : 2014-07-01 DOI: 10.13189/NN.2014.020201

K. Usha, B. Mondal, D. Sengupta, P. Das, K. Mukherjee, P. Kumbhakar

Anatase phase containing nano-crystallite TiO2 thin film is prepared by the peptization of modified Ti-isopropoxide sol using HNO3 as peptizing agent. The resulting sol is concentrated in a rotary evaporator bath. TiO2 film is deposited on ITO substrate by spin coating process. The compact film is annealed at 450˚C and 500˚C for optical studies. The subsequently it is modified as photo-anodes in dye sensitized solar cells. The prepared materials are characterized by X-ray diffraction (XRD), UV-Vis absorption spectroscopy and high resolution transmission electron microscopy (HRTEM). The colloidal particles are 6-8nm in average size while the grain growth of the particles are in the order of 13-20nm after annealing of the thin film. The obtained lattice constants of the TiO2 nanocrystals are a=3.79A and c=9.48A from XRD data as compared to JCPDS data of a=3.79A and c=9.52A. The photo conversion efficiency of assembled dye sensitized solar cells comprising of ~5µm thickness of the film are determined to be of the order of 6.77%.

以HNO3为胶凝剂，对改性ti -异丙醇溶胶进行胶凝，制备了锐钛矿相含纳米晶TiO2薄膜。由此产生的溶胶集中在旋转蒸发器浴。采用自旋镀膜工艺在ITO衬底上沉积TiO2薄膜。薄膜在450℃和500℃下退火，用于光学研究。随后将其修饰为染料敏化太阳能电池中的光阳极。采用x射线衍射(XRD)、紫外可见吸收光谱(UV-Vis)和高分辨率透射电子显微镜(HRTEM)对制备的材料进行了表征。6-8nm的胶体粒子平均尺寸粒子的晶粒生长时的顺序是13-20nm退火后的薄膜。与JCPDS数据的a=3.79A和c=9.52A相比，XRD数据得到的TiO2纳米晶的晶格常数为a=3.79A和c=9.48A。这张照片组装的染料敏化太阳能电池的转换效率包括电影~ 5µm厚度的确定订单的6.77%。

引用次数: 1

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