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Modelling the impact of mass administration of ivermectin in the treatment of onchocerciasis (river blindness) 伊维菌素大规模给药治疗盘尾丝虫病(河盲症)的影响建模
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/23311835.2018.1429700
E. Omondi, F. Nyabadza, R. Smith
Onchocerciasis (river blindness) is a disease spread from black flies to humans. This disease is responsible for chronic morbidity in sub-Saharan Africa. The principal strategy to achieve onchocerciasis elimination is through mass drug administration with ivermectin, a drug that is effective in the short term but wanes quickly. Ivermectin kills the skin-dwelling microfilariae. It may also kill and/or sterilize adult worms. This treatment protocol occurs bi-annually. Consequently, a system of impulsive differential equations is introduced to model both fixed and non-fixed mass drug administration with ivermectin. We determine the threshold for the proportion of treated individuals that reduces the infection in the human population. In the absence of impulsive mass drug administration with ivermectin, we determine the threshold for eradication and carry out stability analysis. The sensitivity analysis results reveal that the disease is unlikely to be eradicated without extremely low transmission levels or strong vector control. If treatment is included, then treatment at fixed intervals can control but not eradicate the disease. Treatment at non-fixed intervals may produce bursts of infection. Thus, bi-annual mass drug administration with ivermectin that is tailored to eradicate onchocerciasis, can only lead to significant reduction of onchocerciasis. However, to achieve 2020/2025 onchocerciasis elimination goals set by World Health Organization, the human-vector contact should be sufficiently reduced and vector control programmes implemented to supplement an intensive and effective mass drug administration with ivermectin.
河盲症是一种由黑蝇传播给人类的疾病。这种疾病是撒哈拉以南非洲地区慢性发病的原因。消除盘尾丝虫病的主要策略是通过伊维菌素的大规模给药,伊维菌素是一种短期有效但迅速消退的药物。伊维菌素杀死皮肤微丝蚴。它还可以杀死和/或消毒成年蠕虫。该治疗方案每两年进行一次。因此,引入了一个脉冲微分方程组来模拟伊维菌素的固定和非固定质量给药。我们确定了在人类中减少感染的接受治疗的个体比例的阈值。在没有伊维菌素脉冲大规模给药的情况下,我们确定根除阈值并进行稳定性分析。敏感性分析结果表明,如果没有极低的传播水平或强有力的媒介控制,这种疾病不太可能根除。如果包括治疗,那么固定间隔的治疗可以控制但不能根除疾病。非固定时间间隔的治疗可能会导致感染爆发。因此,每两年大规模服用一次伊维菌素,专门用于根除盘尾丝虫病,只能显著减少盘尾丝虫病。然而,为了实现世界卫生组织制定的2020/2025年消除盘尾丝虫病的目标,应充分减少人类与病媒的接触,并实施病媒控制方案,以补充伊维菌素的密集有效的大规模药物管理。
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引用次数: 7
Term rank preservers of bisymmetric matrices over semirings 半环上双对称矩阵的项秩保留子
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/25742558.2018.1509430
L. Sassanapitax, S. Pianskool, A. Siraworakun
Abstract In this article, we introduce another standard form of linear preservers. This new standard form provides characterizations of the linear transformations on the set of bisymmetric matrices with zero diagonal and zero antidiagonal over antinegative semirings without zero divisors which preserve some sort of term ranks and preserve the matrix that can be determined as the greatest one. The numbers of all possible linear transformations satisfying each condition are also obtained.
摘要在本文中,我们介绍了线性保护器的另一种标准形式。这个新的标准形式提供了在没有零除数的反负半环上具有零对角和零反对角的双对称矩阵集上的线性变换的特征,这些线性变换保留了某种项秩并保留了可以确定为最大的矩阵。还获得了满足每个条件的所有可能的线性变换的数目。
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引用次数: 0
Correction 修正
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/25742558.2018.1520444
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引用次数: 0
The 2 x n seating derangements 2 x n座位混乱
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/25742558.2018.1492887
Monrudee Sirivoravit, U. Leerawat
Abstract In this paper, we study the derangement of 2n persons sitting 2 rows and n columns. In how many ways can the persons rearrange their seating in accordance with the following condition. Each seat is located by one person and reoccupied by another person and each person moves to a horizontal or a vertical or a diagonal neighboring seat. We establish the system of recurrence relations for the solution of this problem and provide the solution of the system of recurrence relations.
摘要在本文中,我们研究了2n个人坐在2行n列的无序性。根据以下情况,人们可以通过多种方式重新安排座位。每个座位由一个人定位,另一个人重新占据,每个人移动到水平、垂直或对角相邻座位。我们为解决这个问题建立了递推关系系统,并提供了递推系统的解。
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引用次数: 0
On functions and inverses, both positive, decreasing and convex: And Stieltjes functions 关于正、递减和凸的函数和逆:以及Stieltjes函数
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/25742558.2018.1477543
Grant Keady, N. Khajohnsaksumeth, N. Khajohnsaksumeth, B. Wiwatanapataphee
Abstract Any function from onto which is decreasing and convex has an inverse which is positive, decreasing and convex. When has some form of generalized convexity we determine additional convexity properties inherited by . When is positive, decreasing and -convex, its inverse is -convex. Related properties which pertain when is a Stieltjes function are developed. The results are illustrated with the Stieltjes function via a transcendental equation.
任何从其上递减且凸的函数都有一个正的、递减的、凸的逆。当具有某种形式的广义凸性时,我们确定继承的额外凸性性质。当它是正的、递减的和凸的时,它的逆是凸的。开发了与Stieltjes函数何时相关的相关性质。通过超越方程用Stieltjes函数说明了结果。
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引用次数: 2
A new generalized contraction and its application in dynamic programming 一种新的广义收缩及其在动态规划中的应用
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/23311835.2018.1559456
M. Ramezani, H. Ramezani
Abstract By using the idea of Pata [V. Pata, A fixed point theorem in metric spaces. J. Fixed Point Theory Appl. 10 (2011) 299–305.] we establish a new common fixed point theorem and as an application, we prove the existence and uniqueness of common solutions for a class of system of functional equations arising in dynamic programming.
摘要利用Pata的思想[V.Pata,度量空间中的不动点定理。J.fixed point Theory Appl.10(2011)299–305.]我们建立了一个新的公共不动点定理,并作为一个应用,证明了动态规划中一类函数方程组公共解的存在性和唯一性。
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引用次数: 1
Common fixed point results via implicit contractions for multi-valued mappings on b-metric like spaces 类b-度量空间上多值映射的隐式压缩得到公共不动点
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/25742558.2018.1493761
B. Mohammadi, Farhan Golkarmanesh, Vahid Parvaneh
Abstract In this paper, motivated by the recent work [Journal of Nonlinear Sciences and Applications, 10(4):1544–1537] some generalized nonlinear contractive conditions via implicit functions and α-admissible pairs of multi-valued mappings in the setting of b-metric like spaces have been introduced. Some common fixed point results for such mappings in this framework have been provided. Then, some corollaries and consequences for our obtained results are given. Our results are the multi-valued versions of [Journal of Nonlinear Sciences and Applications, 10(4):1544–1537]. An example also is provided to support our obtained results. The presented results generalize and extend some earlier results in the literature.
摘要在最近的工作[非线性科学与应用杂志,10(4):1544–1537]的推动下,本文通过隐函数和多值映射的α-容许对,在b-度量类空间的设置中引入了一些广义非线性压缩条件。已经提供了该框架中这种映射的一些常见的不动点结果。然后,给出了我们得到的结果的一些推论和结果。我们的结果是[非线性科学与应用杂志,10(4):1544-1537]的多值版本。还提供了一个例子来支持我们获得的结果。所给出的结果推广和推广了文献中的一些早期结果。
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引用次数: 2
Probability density and stochastic stability for the coupled Van der Pol oscillator system 耦合Van der Pol振荡系统的概率密度和随机稳定性
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/23311835.2018.1431092
Sheng-hong Li, Quanxin Zhu
Abstract In this paper, the probability density and almost sure asymptotic stability of the coupled Van der Pol oscillator system under the noise excitations are investigated. Through the stochastic averaging method and slow changing process theorem, averaged Fokker–Planck–Kolmogorov equation and exact solution of the dynamical system are obtained. Especially, the marginal density functions of the system excited by the additive white noises are derived. Then, the effects of coupled parameters and noise parameters on the marginal density functions are discussed through the numerical figures. In addition, the almost sure asymptotic stability under the parametric excitation by means of the maximal Lyapunov exponent is studied, and the stable demarcation points about noise intensity are presented.
摘要本文研究了耦合Van der Pol振荡系统在噪声激励下的概率密度和几乎肯定渐近稳定性。通过随机平均法和慢变过程定理,得到了动力系统的平均Fokker–Planck–Kolmogorov方程和精确解。特别推导了系统在加性白噪声激励下的边缘密度函数。然后,通过数值计算讨论了耦合参数和噪声参数对边缘密度函数的影响。此外,利用最大李雅普诺夫指数研究了参数激励下的几乎肯定渐近稳定性,并给出了噪声强度的稳定分界点。
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引用次数: 3
Convergence in fractional probability space and 0-1 Kolmogorov theorem 分数概率空间的收敛性和0-1 Kolmogorov定理
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/25742558.2018.1475612
A. Zendehdel, Parisa Ahmadi Ghotbi
Abstract In this study, we define the fractional random variable. The concept of convergence in fractional probability, almost surely convergence and some related theorems and examples are studied with the purpose of expanding the fractional probability theory parallel to the classical one. It is shown that almost surely convergence in the fractional probability space does not lead to the convergence in fractional probability. And, some valuable features related to fractional probability theory such as Cauchy function in fractional probability are discussed. We proved that a fractional random variable converges in fractional probability if it is Cauchy in fractional probability. Finally, the well-known 0-1 Kolmogorov theorem is proved in a fractional probability space.
在本研究中,我们定义了分数随机变量。研究了分数阶概率论的收敛性、几乎必然收敛性的概念,并给出了一些相关的定理和例子,目的是将分数阶概率论扩展到与经典概率论平行的领域。证明了分数阶概率空间的收敛几乎肯定不会导致分数阶概率空间的收敛。讨论了分数阶概率论的一些有价值的特征,如分数阶概率论中的柯西函数。证明了分数阶随机变量在分数阶概率上是柯西的情况下收敛于分数阶概率。最后,在分数阶概率空间中证明了著名的0-1 Kolmogorov定理。
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引用次数: 0
The Gompertz Inverse Exponential (GoIE) distribution with applications Gompertz逆指数(GoIE)分布及其应用
Q4 MATHEMATICS Pub Date : 2018-01-01 DOI: 10.1080/25742558.2018.1507122
P. E. Oguntunde, M. A. Khaleel, A. Adejumo, H. Okagbue, A. Opanuga, F. Owolabi
Abstract The Gompertz inverse exponential (GoIE) distribution using the Gompertz generalized family of distributions was derived and introduced in this article. Some basic statistical properties of the model were derived and discussed in minute details. The model parameters were estimated using the maximum likelihood estimation method. Real-life applications were provided and the GoIE distribution provides better fits than the Gompertz exponential, Gompertz Weibull and Gompertz Lomax distributions.
摘要本文利用Gompertz广义分布族导出并引入了Gompertz-逆指数分布。导出了该模型的一些基本统计特性,并对其进行了详细讨论。使用最大似然估计方法来估计模型参数。提供了实际应用,GoIE分布比Gompertz指数、Gompertz-Weibull和Gompertz-Lomax分布提供了更好的拟合。
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引用次数: 15
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Cogent mathematics & statistics
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