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Comparing the clinical accuracy of urine exfoliated cell examination and fluorescence in situ hybridization in the diagnosis of upper urinary tract urothelial carcinoma. 比较尿脱落细胞检查与荧光原位杂交诊断上尿路尿路上皮癌的临床准确性。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-12 DOI: 10.1186/s12894-025-02041-w
Chundan Wang, Yufeng Liu, Chunli Zhang, Changliang Wang, Jianjun Wu, Fengchun Xiao, Juan Jin
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引用次数: 0
A feasibility study of a novel irrigation technique for reducing intrapelvic pressure during ureterorenoscopy using conventional devices. 输尿管镜检查中使用传统设备降低盆腔内压力的新型灌洗技术的可行性研究。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-10 DOI: 10.1186/s12894-025-02039-4
Naoya Sugihara, Reina Kono, Hirofumi Sogabe, Kaori Saiki, Haruna Arai, Osuke Arai, Tomoya Onishi, Toshio Kakuda, Koji Hara, Ryuta Watanabe, Noriyoshi Miura, Akira Ozawa, Tokuhiro Iseda, Takashi Saika
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引用次数: 0
Neoadjuvant immunotherapy combined with HER2-targeted antibody-drug conjugate in bladder urothelial carcinoma: a case report. 新辅助免疫治疗联合her2靶向抗体药物偶联治疗膀胱尿路上皮癌1例报告。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-10 DOI: 10.1186/s12894-026-02049-w
Zhengmin Guo, Guodong Wang
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引用次数: 0
Clinical reasoning with machines: evaluating the interpretive depth of AI in urological case assessments. 机器临床推理:评价人工智能在泌尿科病例评估中的解释深度。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-09 DOI: 10.1186/s12894-026-02048-x
Arda Taşkın Taşkıran, Ahmet Yıldırım Balık, Ekrem Başaran, Dursun Baba, Muhammet Ali Kayıkçı
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引用次数: 0
Post Fournier gangrene raw areas in the penis or scrotum: the role of intense pulsed light and radiofrequency in conservative treatment. 阴茎或阴囊内富尼耶坏疽原发区:强脉冲光和射频在保守治疗中的作用。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-08 DOI: 10.1186/s12894-025-02021-0
Nader Elmelegy, Mohamed Elghazaly, Dalia Nader

Background: For infected wounds, including clostridial myonecrosis, necrotizing soft tissue infections, and Fournier's gangrene, hyperbaric oxygen therapy (HBOT) is advised; however, tension pneumothorax and gas emboli may occur during the process. Other instances of relative contraindications include illnesses like asthma and chronic obstructive lung disease. We can use radio frequency and strong pulsed light in our research without having to worry about these kinds of issues and could have a significant impact on improving treatment outcomes.

Objective: To assess how well intensely pulsed light and radiofrequency work for treating the aftereffects of post-Fournier's gangrene.

Patients and method: Intense pulsed light and radiofrequency sessions were used to treat sixteen male patients with isolated penile or scrotal post-Fournier's gangrene raw areas.

Results: Twelve patients (75%) had an excellent satisfaction rate, and four (25%) rated it as good. No fair or poor results were documented.

Conclusion: We are unable to make significant conclusions because of the small number of patients; however, since E-light is a simple, effective, and affordable treatment with good outcomes and no side effects, we advise more research on its application in the treatment of post-Fournier's gangrene isolated raw areas of the scrotum and penis.

背景:对于感染伤口,包括梭状菌性肌坏死、坏死性软组织感染和富尼耶坏疽,建议高压氧治疗(HBOT);然而,在此过程中可能发生张力性气胸和气体栓塞。其他相对禁忌症包括哮喘和慢性阻塞性肺病等疾病。我们可以在研究中使用射频和强脉冲光,而不必担心这些问题,并且可以对改善治疗效果产生重大影响。目的:探讨强脉冲光与射频治疗后富尼耶坏疽后遗症的效果。患者和方法:采用强脉冲光和射频治疗16例男性孤立性阴茎或阴囊后富尼耶坏疽生区。结果:12例(75%)患者满意度为优,4例(25%)患者满意度为良。没有记录公平或差的结果。结论:由于患者数量少,我们无法得出有意义的结论;然而,由于E-light是一种简单、有效、价格合理、效果良好且无副作用的治疗方法,我们建议更多地研究其在治疗后富尼耶坏疽孤立性阴囊和阴茎原始区域的应用。
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引用次数: 0
Readability and quality assessment of AI-powered chatbot responses to overactive bladder patient questions: a comparative study. 人工智能聊天机器人回答膀胱过度活动患者问题的可读性和质量评估:一项比较研究。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-08 DOI: 10.1186/s12894-025-02033-w
Mutlu Deger, Tunahan Ates, Ismail Onder Yilmaz, Mehmet Gurkan Arıkan, Ibrahim Halil Sukur, Fesih Ok, Nebil Akdogan, Volkan Izol

Introduction: Overactive bladder (OAB) is a common urological condition affecting millions of people worldwide, significantly reducing their quality of life. Patient compliance and active participation in disease management are critical to achieving successful outcomes. This study aims to understand the potential role of AI-assisted chatbots in educating patients with OAB and their impact on health literacy.

Methods: We compared responses from four AI chatbots (ChatGPT, DeepSeek, Claude, and Gemini) to 16 standardized questions from the AUA Overactive Bladder Patient Guide. Two board-certified urologists independently evaluated responses using Ensuring Quality Information for Patients (EQIP) tool and Google E-E-A-T principles.

Results: Inter-rater reliability was excellent (ICC = 0.97 for EQIP, κ = 0.89 for E-E-A-T). A significant difference was found between chatbots in terms of readability scores (Gunning Fox Index p = 0.008, Flesch-Kincaid Grade Level p < 0.001), with all responses requiring education levels above the recommended 6th-8th grade. However, significant differences emerged in information quality (EQIP, p < 0.001; E-E-A-T, p < 0.001). Gemini demonstrated superior performance in both EQIP (60.2 ± 6.92) and E-E-A-T scores (13.5) compared to all other chatbots.

Conclusion: AI chatbots show potential for patient education but produce content with readability levels too complex for general audiences. Significant quality variations exist between models. These findings emphasize the need for collaboration between healthcare professionals and AI developers to create more accessible, reliable health information systems.

膀胱过动症(OAB)是一种常见的泌尿系统疾病,影响着全世界数百万人,显著降低了他们的生活质量。患者的依从性和积极参与疾病管理是取得成功结果的关键。本研究旨在了解人工智能辅助聊天机器人在教育OAB患者方面的潜在作用及其对健康素养的影响。方法:我们比较了四个AI聊天机器人(ChatGPT、DeepSeek、Claude和Gemini)对来自AUA膀胱过动症患者指南的16个标准化问题的回答。两名委员会认证的泌尿科医生使用确保患者质量信息(EQIP)工具和谷歌E-E-A-T原则独立评估反应。结果:评估者间信度极好(EQIP的ICC = 0.97, E-E-A-T的κ = 0.89)。在可读性得分方面,聊天机器人之间存在显著差异(Gunning Fox Index p = 0.008, Flesch-Kincaid Grade Level p)。结论:AI聊天机器人显示出患者教育的潜力,但产生的内容可读性水平对普通受众来说过于复杂。模型之间存在显著的质量差异。这些发现强调了卫生保健专业人员和人工智能开发人员之间需要合作,以创建更容易获得、更可靠的卫生信息系统。
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引用次数: 0
MXRA8, a key palmitoylation-related gene, promotes bladder cancer progression via remodeling tumor microenvironment and predicts poor prognosis. MXRA8是一个关键的棕榈酰化相关基因,通过重塑肿瘤微环境促进膀胱癌的进展,并预测预后不良。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-08 DOI: 10.1186/s12894-026-02046-z
Hailong Wang, Ye Xiong, Tianchi He, Mingyang He, Jun Deng, Dianbin Song, Zhipeng Wang
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引用次数: 0
The efficacy of super-lubricous Foley catheters in indwelling catheterization: a randomized controlled trial. 超润滑Foley导尿管留置导尿的疗效:一项随机对照试验。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-07 DOI: 10.1186/s12894-025-02035-8
Yu-Lan Zhu, Min Liao, Yu Luo, Zhi-Yu Li, Ka Li

Objective: This randomized controlled trial evaluated the clinical efficacy of super-lubricous Foley catheters in reducing urethral complications during indwelling catheterization. Focusing on addressing friction-induced injuries, the study assessed four outcomes: 1) urethral adverse reactions; 2) urethral trauma and inflammatory responses; 3) patient comfort; and 4) post-removal voiding symptoms.

Methods: A total of 114 patients from a tertiary hospital (December 2023-June 2024) were randomly allocated into two arms: 57 individuals in the experimental arm were treated with super-lubricous Foley catheters, whereas the same number in the control arm received conventional catheters. Primary outcomes included bladder irritation and urethral pain. Secondary outcomes encompassed urethral injury (red blood cells and epithelial cells), inflammation (white blood cells), comfort metrics (activity restriction, sleep disturbance, anxiety), and voiding parameters (dysuria, urinary hesitation, incomplete bladder emptying and lower abdominal pain).

Results: The baseline data revealed no statistically meaningful differences between the two groups. (all P > 0.05). The experimental group demonstrated significantly lower overall rates of bladder irritation (31.6% vs. 50.9%, P < 0.05) and urethral pain during catheterization (14.0% vs. 31.6%, P < 0.05). Notably, urinary epithelial cells (median 6 vs. 13.5/HP) and leukocytes (31 vs. 81/μL) were reduced in the experimental group (P < 0.05). Activity restriction rates decreased significantly (42.1% vs. 68.4%, P < 0.05), and first void volume improved (200 vs. 150 mL, P < 0.05). There were no meaningful differences between groups in the occurrence of the four urination-related symptoms-including dysuria, urinary hesitation, incomplete bladder emptying, and lower abdominal pain (all P > 0.05).

Conclusion: Super-lubricous Foley catheters effectively mitigate bladder irritation, urethral trauma, and inflammation while enhancing patient mobility. However, they show limited efficacy in alleviating post-removal voiding dysfunction. These findings support the clinical adoption of super-lubricous Foley catheters for reducing catheterization-related complications.

Trial registration: This study was a randomized controlled trial registered at Chinese Clinical Trial Registry (ChiCTR2300078483, https://www.chictr.org.cn/ ) on 11 December 2023.

目的:本随机对照试验评价超润滑Foley导尿管减少留置导尿过程中尿道并发症的临床疗效。该研究以解决摩擦性损伤为重点,评估了四个结果:1)尿道不良反应;2)尿道创伤及炎症反应;3)患者舒适度;4)拔牙后排尿症状。方法:选取某三级医院2014年12月~ 2024年6月114例患者,随机分为两组:实验组57例使用超润滑Foley导尿管,对照组57例使用常规导尿管。主要结局包括膀胱刺激和尿道疼痛。次要结局包括尿道损伤(红细胞和上皮细胞)、炎症(白细胞)、舒适指标(活动受限、睡眠障碍、焦虑)和排尿参数(排尿困难、排尿犹豫、膀胱排空不全和下腹痛)。结果:基线数据显示两组间无统计学意义差异。(P < 0.05)。实验组膀胱刺激发生率明显低于对照组(31.6% vs. 50.9%, P < 0.05)。结论:超润滑Foley导尿管可有效减轻膀胱刺激、尿道创伤和炎症,同时增强患者的活动能力。然而,它们在缓解拔除后排尿功能障碍方面的效果有限。这些发现支持临床采用超润滑Foley导管来减少导管相关并发症。试验注册:本研究是一项随机对照试验,于2023年12月11日在中国临床试验注册中心注册(ChiCTR2300078483, https://www.chictr.org.cn/)。
{"title":"The efficacy of super-lubricous Foley catheters in indwelling catheterization: a randomized controlled trial.","authors":"Yu-Lan Zhu, Min Liao, Yu Luo, Zhi-Yu Li, Ka Li","doi":"10.1186/s12894-025-02035-8","DOIUrl":"10.1186/s12894-025-02035-8","url":null,"abstract":"<p><strong>Objective: </strong>This randomized controlled trial evaluated the clinical efficacy of super-lubricous Foley catheters in reducing urethral complications during indwelling catheterization. Focusing on addressing friction-induced injuries, the study assessed four outcomes: 1) urethral adverse reactions; 2) urethral trauma and inflammatory responses; 3) patient comfort; and 4) post-removal voiding symptoms.</p><p><strong>Methods: </strong>A total of 114 patients from a tertiary hospital (December 2023-June 2024) were randomly allocated into two arms: 57 individuals in the experimental arm were treated with super-lubricous Foley catheters, whereas the same number in the control arm received conventional catheters. Primary outcomes included bladder irritation and urethral pain. Secondary outcomes encompassed urethral injury (red blood cells and epithelial cells), inflammation (white blood cells), comfort metrics (activity restriction, sleep disturbance, anxiety), and voiding parameters (dysuria, urinary hesitation, incomplete bladder emptying and lower abdominal pain).</p><p><strong>Results: </strong>The baseline data revealed no statistically meaningful differences between the two groups. (all P > 0.05). The experimental group demonstrated significantly lower overall rates of bladder irritation (31.6% vs. 50.9%, P < 0.05) and urethral pain during catheterization (14.0% vs. 31.6%, P < 0.05). Notably, urinary epithelial cells (median 6 vs. 13.5/HP) and leukocytes (31 vs. 81/μL) were reduced in the experimental group (P < 0.05). Activity restriction rates decreased significantly (42.1% vs. 68.4%, P < 0.05), and first void volume improved (200 vs. 150 mL, P < 0.05). There were no meaningful differences between groups in the occurrence of the four urination-related symptoms-including dysuria, urinary hesitation, incomplete bladder emptying, and lower abdominal pain (all P > 0.05).</p><p><strong>Conclusion: </strong>Super-lubricous Foley catheters effectively mitigate bladder irritation, urethral trauma, and inflammation while enhancing patient mobility. However, they show limited efficacy in alleviating post-removal voiding dysfunction. These findings support the clinical adoption of super-lubricous Foley catheters for reducing catheterization-related complications.</p><p><strong>Trial registration: </strong>This study was a randomized controlled trial registered at Chinese Clinical Trial Registry (ChiCTR2300078483, https://www.chictr.org.cn/ ) on 11 December 2023.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":" ","pages":"30"},"PeriodicalIF":1.9,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12870102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145917134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for steinstrasse formation after extracorporeal shock wave lithotripsy for renal pelvic stones. 体外冲击波碎石术治疗肾盂结石后尿路形成的危险因素。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-06 DOI: 10.1186/s12894-025-02044-7
Mubariz Aydamirov, Kadir Karkin, Guclu Gurlen, Ergun Alma, Adem Altunkol, Eyup Kaplan, Bugra Aksay, Gurkan Akbulut, Hakan Sigva, Ediz Vuruskan, Muslum Ahmet Tunckiran

Background: This study aimed to identify predictive factors for the formation of steinstrasse following extracorporeal shock wave lithotripsy (SWL) in patients with medium-sized (10-20 mm) renal pelvic stones.

Methods: This retrospective cohort study, data of 718 patients who underwent SWL for urinary tract stones were analyzed and single, unilateral, radio-opaque renal pelvic stones were included in the study. Patient age, sex, stone side, shape (round/non-round), size, surface area (SA), and presence of hydronephrosis were recorded. Patients were divided into two groups depending on the presence of steinstrasse: Group 1 (with steinstrasse) and Group 2 (without). Demographic, clinical, and radiological parameters were compared between the groups.

Results: The mean age of the patients was 50.8 ± 11.2 years. The average number of SWL sessions was 2 (range 1-4). Group 1 included 12 patients (23.1%), while Group 2 comprised 40 patients (76.9%). The mean SA in Group 1 was significantly higher than in Group 2 (145.43 vs. 111.69 mm2; p = 0.044). Round stones were more frequently observed in Group 1, whereas non-round stones predominated in Group 2 (83.3% vs. 62.5%, respectively; p = 0.008). The overall SWL success rate was determined as 76.9%. Logistic regression analysis revealed that round stones increased the risk of steinstrasse by 8.333 times (OR = 8.333, 95% CI = 1.604-43.288, p = 0.012).

Conclusions: SA was higher in patients who developed steinstrasse. Since the likelihood of steinstrasse formation is elevated in medium-sized round renal pelvic stones, pre-stenting may be appropriate.

背景:本研究旨在确定中等大小(10- 20mm)肾盂结石患者体外冲击波碎石术(SWL)后结石形成的预测因素。方法:本回顾性队列研究分析了718例因尿路结石行SWL的患者的资料,其中包括单侧、单侧、放射性不透明的肾盂结石。记录患者的年龄、性别、结石的侧面、形状(圆形/非圆形)、大小、表面积(SA)和是否存在肾积水。患者根据有无steinstrasse分为两组:1组(有steinstrasse)和2组(无steinstrasse)。比较两组间的人口学、临床和放射学参数。结果:患者平均年龄50.8±11.2岁。SWL会话的平均次数为2(范围1-4)。组1 12例(23.1%),组2 40例(76.9%)。第1组的平均SA明显高于第2组(145.43 vs 111.69 mm2, p = 0.044)。1组以圆形结石多见,2组以非圆形结石多见(83.3% vs. 62.5%, p = 0.008)。SWL的总成功率为76.9%。Logistic回归分析显示,圆形结石增加了8.333倍(OR = 8.333, 95% CI = 1.604 ~ 43.288, p = 0.012)。结论:SA在发生肌张力增高的患者中较高。由于中等大小的圆形肾盂结石有可能形成镫骨,因此预先支架置入可能是合适的。
{"title":"Risk factors for steinstrasse formation after extracorporeal shock wave lithotripsy for renal pelvic stones.","authors":"Mubariz Aydamirov, Kadir Karkin, Guclu Gurlen, Ergun Alma, Adem Altunkol, Eyup Kaplan, Bugra Aksay, Gurkan Akbulut, Hakan Sigva, Ediz Vuruskan, Muslum Ahmet Tunckiran","doi":"10.1186/s12894-025-02044-7","DOIUrl":"10.1186/s12894-025-02044-7","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to identify predictive factors for the formation of steinstrasse following extracorporeal shock wave lithotripsy (SWL) in patients with medium-sized (10-20 mm) renal pelvic stones.</p><p><strong>Methods: </strong>This retrospective cohort study, data of 718 patients who underwent SWL for urinary tract stones were analyzed and single, unilateral, radio-opaque renal pelvic stones were included in the study. Patient age, sex, stone side, shape (round/non-round), size, surface area (SA), and presence of hydronephrosis were recorded. Patients were divided into two groups depending on the presence of steinstrasse: Group 1 (with steinstrasse) and Group 2 (without). Demographic, clinical, and radiological parameters were compared between the groups.</p><p><strong>Results: </strong>The mean age of the patients was 50.8 ± 11.2 years. The average number of SWL sessions was 2 (range 1-4). Group 1 included 12 patients (23.1%), while Group 2 comprised 40 patients (76.9%). The mean SA in Group 1 was significantly higher than in Group 2 (145.43 vs. 111.69 mm<sup>2</sup>; p = 0.044). Round stones were more frequently observed in Group 1, whereas non-round stones predominated in Group 2 (83.3% vs. 62.5%, respectively; p = 0.008). The overall SWL success rate was determined as 76.9%. Logistic regression analysis revealed that round stones increased the risk of steinstrasse by 8.333 times (OR = 8.333, 95% CI = 1.604-43.288, p = 0.012).</p><p><strong>Conclusions: </strong>SA was higher in patients who developed steinstrasse. Since the likelihood of steinstrasse formation is elevated in medium-sized round renal pelvic stones, pre-stenting may be appropriate.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":" ","pages":"29"},"PeriodicalIF":1.9,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12870227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of large language models in assigning PI-RADS v2.1 categories for prostate MRI reports. 大语言模型在前列腺MRI报告PI-RADS v2.1分类中的评价。
IF 1.9 3区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2026-01-02 DOI: 10.1186/s12894-025-02038-5
Betul Akdal Dolek, Muhammed Said Besler
{"title":"Evaluation of large language models in assigning PI-RADS v2.1 categories for prostate MRI reports.","authors":"Betul Akdal Dolek, Muhammed Said Besler","doi":"10.1186/s12894-025-02038-5","DOIUrl":"10.1186/s12894-025-02038-5","url":null,"abstract":"","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":" ","pages":"27"},"PeriodicalIF":1.9,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12866120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145896471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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BMC Urology
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