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Perspectives in drug discovery and design : PD3最新文献

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Mohs Micrographic Surgery in Skin of Color. 有色人种皮肤的莫氏显微外科手术。
IF 1.5
Perspectives in drug discovery and design : PD3
Pub Date : 2022-05-01 DOI: 10.36849/JDD.6469
Ramone Williams, David Ciocon

The United States population is becoming increasingly diverse. Data show increased utilization of Mohs micrographic surgery (MMS) in people of color. Though the incidence of skin cancer in skin of color is low, morbidity and mortality are disproportionately high. Still, published literature on the topic is lacking. In this article, we outline our approach to MMS in skin of color. We review salient topics not published elsewhere in literature in this context, including post-operative postinflammatory hyperpigmentation and suture selection in skin of color. Our goal is to better equip dermatologic surgeons for the rapidly changing demographics of our patient population. We feel this is an important step in addressing the dire health disparities associated with skin cancer in skin of color. J Drugs Dermatol. 2022;21(5):536-541. doi:10.36849/JDD.6469.

美国人口日益多元化。数据显示，有色人种越来越多地使用莫氏显微外科手术（MMS）。虽然有色人种皮肤癌的发病率较低，但发病率和死亡率却高得不成比例。但有关该主题的公开文献仍然缺乏。在本文中，我们将概述我们对有色人种皮肤 MMS 的研究方法。我们回顾了在这方面其他文献中未发表的突出话题，包括有色人种皮肤的术后炎症性色素沉着和缝合线选择。我们的目标是让皮肤外科医生更好地应对快速变化的患者群体。我们认为这是解决有色人种皮肤癌相关的严重健康问题的重要一步。J Drugs Dermatol.2022;21(5):536-541. doi:10.36849/JDD.6469.
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引用次数: 0
Explicit Calculation of 3D Molecular Similarity 三维分子相似度的显式计算
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1007/0-306-46857-3_17
A. Good, W. Richards
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引用次数: 26
New 3D Molecular Descriptors: The WHIM theory and QSAR Applications 新型三维分子描述符:WHIM理论及其QSAR应用
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1007/0-306-46857-3_19
R. Todeschini, P. Gramatica
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引用次数: 85
Receptor-based prediction of binding affinities 基于受体的结合亲和力预测
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1007/0-306-46857-3_3
Tudor I. Oprea, G. Marshall
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引用次数: 32
Comparative Binding Energy Analysis 比较结合能分析
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1023/A:1027247618908
R. Wade, A. Ortiz, F. Gago
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引用次数: 20
Molecular mechanics calculations on protein-ligand complexes 蛋白质-配体复合物的分子力学计算
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1023/A:1027207904795
I. Weber, R. Harrison
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引用次数: 9
Density-Functional Theory Investigations of Enzyme-substrate Interactions 酶-底物相互作用的密度-功能理论研究
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1023/A:1027216106612
P. Carloni, F. Alber
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引用次数: 2
Some Biological Applications of Semiempirical MO Theory 半经验MO理论的一些生物学应用
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1023/A:1027259921634
B. Beck, T. Clark
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引用次数: 11
The Use of Self-organizing Neural Networks in Drug Design 自组织神经网络在药物设计中的应用
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1007/0-306-46857-3_15
S. Anzali, J. Gasteiger, U. Holzgrabe, J. Polanski, J. Sadowski, A. Teckentrup, M. Wagener
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引用次数: 50
Density-Functional Theory and Molecular Dynamics: A New Perspective for Simulations of Biological Systems 密度泛函理论与分子动力学:生物系统模拟的新视角
Perspectives in drug discovery and design : PD3
Pub Date : 2002-01-01 DOI: 10.1007/0-306-46857-3_9
W. Andreoni
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引用次数: 2
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