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Two Patients With Resistant Immune Thrombocytopenic Purpura and Portal Hypertension Treated Safely With Laparoscopic Splenectomy: A Case Series Report and Literature Review 腹腔镜脾切除术安全治疗顽固性免疫性血小板减少性紫癜和门脉高压症2例:病例系列报告及文献复习
Pub Date : 2019-12-19 DOI: 10.14740/jcs399
Mujtaba Mohamed, A. Alhillan, I. Patel, Arman Mushtaq, E. Zurkovsky, Christian Kaunzinger, Mohammad A. Hossain
Immune thrombocytopenia (previously called idiopathic thrombocytopenic purpura (ITP)) is characterized by an autoimmune destruction and clearance of platelets and megakaryocytes by reticuloendothelial system including liver and spleen. Most of the time, it occurs in the absence of any obvious stimulus. Secondary immune thrombocytopenia coexists with an underlying disease such as human immunodeficiency virus (HIV), hepatitis C virus (HCV), chronic lymphocytic leukemia (CLL), systemic lupus erythematosus (SLE), or can occur following exposure to certain drugs such as heparin or quinidine. Medical treatment includes corticosteroids, intravenous immunoglobulins and rituximab. Splenectomy is reserved for patients who fail medical therapy. Laparoscopic splenectomy is safer than open splenectomy. The main surgical complication of splenectomy is intra-abdominal bleeding. Additional risk factors for post-operative bleeding such as portal hypertension can alter treatment decision in regard to splenectomy. J Curr Surg. 2019;9(4):61-65 doi: https://doi.org/10.14740/jcs399
免疫性血小板减少症(以前称为特发性血小板减少性紫癜(ITP))的特征是自身免疫破坏和包括肝脏和脾脏在内的网状内皮系统对血小板和巨核细胞的清除。大多数时候,它是在没有任何明显刺激的情况下发生的。继发性免疫性血小板减少症与潜在疾病共存,如人类免疫缺陷病毒(HIV)、丙型肝炎病毒(HCV)、慢性淋巴细胞白血病(CLL)、系统性红斑狼疮(SLE),或暴露于某些药物(如肝素或奎尼丁)后发生。药物治疗包括皮质类固醇、静脉注射免疫球蛋白和利妥昔单抗。脾切除术是为药物治疗失败的病人保留的。腹腔镜脾切除术比开放脾切除术更安全。脾切除术的主要手术并发症是腹腔出血。术后出血的其他危险因素如门静脉高压可改变脾切除术的治疗决定。中华外科杂志,2019;9(4):61-65 doi: https://doi.org/10.14740/jcs399
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引用次数: 0
Comparison of 3% vs. 23.4% Hypertonic Saline in Traumatic Brain Injury 3%与23.4%高渗盐水治疗外伤性脑损伤的比较
Pub Date : 2019-12-19 DOI: 10.14740/jcs389
D. Traficante, D. Galaktionova, Urielle Marseille, Steven M Hochman, Jamshed Zuberi, Robert V. Madlinger
Background: Hypertonic saline (HTS) is an effective treatment for patients with increased intracranial pressure (ICP) secondary to traumatic brain injury (TBI). The ideal concentration for use in these patients is not well defined. The aim of our study was to compare Glasgow coma scale (GCS) and mortality of patients after administration of 3% vs. 23.4% HTS in the initial resuscitation. Methods: We performed a retrospective analysis of patients admitted to the surgical intensive care unit (ICU) under the trauma service with a diagnosis of TBI who received HTS during initial resuscitation. Patient medical records were reviewed to collect data including in-hospital mortality, ICU length of stay, hospital length of stay, GCS at the time of admission and discharge, serum sodium and serum osmolality values at 24, 48 and 72 h after arrival, acute kidney injury and severe hypernatremia. Results: Patients ≥ 18 years of age admitted to trauma ICU with a diagnosis of TBI. Pregnant, incarcerated, or non-traumatic intracranial hemorrhage patients were excluded. Thirty-one patients were included in the study. The 3% arm included 21 patients, and 23.4% arm had 10 patients. All patients received 3% HTS continuous infusion following initial bolus. Median injury severity scores (ISS) were 22 vs. 25 in the 3% vs. 23.4% HTS groups, respectively (P = 0.37). There was no difference in in-hospital mortality between the two groups (52.4% vs. 50.0%, P = 0.45). There was a significant improvement in GCS at discharge, 8.3% vs. 44.4% in 3% HTS vs. 23.4% HTS arms, respectively (P = 0.029). Patients reaching goal serum sodium and serum osmolality at 24 h was significantly higher in the 23.4% group (33.3% vs. 70.0%; P = 0.028 and 35.7% vs. 77.8%; P = 0.026, respectively). Significant increase in incidence of severe hypernatremia in the 23.4% arm was noted (0.0% vs. 40.0%, P = 0.009). Conclusion: This study demonstrates no significant difference in in-hospital mortality for patients who received 3% vs. 23.4% HTS. Significantly higher percentage of patients receiving 23.4% HTS reached goal serum sodium and osmolality levels at 24 h with a concomitant significantly increased rate of severe hypernatremia. J Curr Surg. 2019;9(4):39-44 doi: https://doi.org/10.14740/jcs389
背景:高渗生理盐水(HTS)是治疗外伤性脑损伤(TBI)继发性颅内压增高的有效方法。在这些患者中使用的理想浓度还没有很好的定义。本研究的目的是比较初始复苏时给予3% HTS和23.4% HTS后患者的格拉斯哥昏迷评分(GCS)和死亡率。方法:我们对创伤科外科重症监护病房(ICU)诊断为TBI并在首次复苏期间接受HTS治疗的患者进行回顾性分析。回顾患者病历,收集住院死亡率、ICU住院时间、住院时间、入院和出院时的GCS、入院后24、48和72 h的血清钠和血清渗透压值、急性肾损伤和重度高钠血症等数据。结果:年龄≥18岁且诊断为TBI的患者入住创伤ICU。排除孕妇、嵌顿或非外伤性颅内出血患者。31名患者参与了这项研究。3%组21例,23.4%组10例。所有患者在初始丸后接受3% HTS持续输注。3%和23.4% HTS组中位损伤严重程度评分(ISS)分别为22和25 (P = 0.37)。两组住院死亡率无差异(52.4% vs 50.0%, P = 0.45)。出院时GCS显著改善,3% HTS组为8.3%,23.4% HTS组为44.4% (P = 0.029)。23.4%组24 h达到目标血清钠和血清渗透压的患者显著高于23.4%组(33.3% vs. 70.0%;P = 0.028, 35.7% vs. 77.8%;P = 0.026)。23.4%组的严重高钠血症发生率显著增加(0.0%比40.0%,P = 0.009)。结论:本研究显示接受3% HTS和23.4% HTS治疗的患者住院死亡率无显著差异。接受23.4% HTS治疗的患者在24小时达到目标血清钠和渗透压水平的比例明显更高,同时严重高钠血症的发生率显著增加。中华外科杂志,2019;9(4):39-44 doi: https://doi.org/10.14740/jcs389
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引用次数: 3
Management of Chest Trauma in a Rural Medical College Hospital 某农村医学院附属医院胸外伤的处理
Pub Date : 2019-09-16 DOI: 10.14740/jcs379
K. Alam, S. Rahman, S. Saad
Background: Chest trauma implies trauma to anyone or combination of different thoracic structures. Approximately in one quarter of civilians, trauma deaths are caused by trauma to thorax. Many of these deaths can be avoided by precise clinical diagnosis and immediate management. Most wounds under these situations could be managed conservatively with or without tube thoracostomy. This study aims to assess and analyze the mode of presentation, pattern and management of chest injuries in rural areas. Methods: One hundred consecutive patients within the period of 14 months with thoracic trauma presenting in emergency department were evaluated. Results: Most of the patients (87%) were treated conservatively with minor wound repair and medical treatment and 13% patients had been treated with intercostal chest drain. Among these 13% patients, three were referred to higher centers due to massive initial hemothorax and longstanding pneumothorax. Conclusions: Majority of the chest injury patients can be treated satisfactorily in general surgery unit by conservative management or chest drain. J Curr Surg. 2019;9(2-3):22-25 doi: https://doi.org/10.14740/jcs379
背景:胸部创伤是指对任何人或不同胸腔结构的组合造成的创伤。大约四分之一的平民因创伤死亡是由胸部创伤造成的。通过精确的临床诊断和及时的治疗,许多死亡是可以避免的。在这种情况下,大多数伤口可以保守处理,有或没有管开胸术。本研究旨在评估和分析农村地区胸部损伤的表现模式、类型和处理方法。方法:对连续14个月就诊于急诊科的100例胸部外伤患者进行回顾性分析。结果:绝大多数(87%)患者采用小创面修复和内科治疗,13%的患者采用肋间胸腔引流。在这13%的患者中,有3例由于大量的初始血胸和长期气胸而转诊到更高的中心。结论:多数胸外伤患者在普外科采用保守治疗或胸腔引流均能得到满意的治疗。中华外科杂志,2019;9(2-3):22-25 doi: https://doi.org/10.14740/jcs379
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引用次数: 1
Analysis of Outcomes Using Intraoperative Irrigation and Drainage for Complicated Appendicitis 术中冲洗引流治疗复杂性阑尾炎疗效分析
Pub Date : 2019-09-16 DOI: 10.14740/jcs385
M. Sridhar, Manrique A. Guerrero, Jacob Miller, P. Hanna, J. Haghshenas, Jamshed Zuberi
Background: The practice of irrigation and/or intraoperative peritoneal drain placement during an appendectomy for complicated appendicitis is currently controversial. This study was aimed at delineating the relationship between the practice of intraoperative drain placement and/or irrigation and patient outcomes for complicated appendicitis cases. Methods: A retrospective study of patients presenting with acute complicated appendicitis, which was defined as perforated or gangrenous, was conducted (n = 225). The primary outcome was defined as the presence of postoperative abscess or sepsis, while the secondary outcome measured was length of hospital stay. Results: Patients who received intraoperative drain placement had an increased risk of postoperative abscess (odds ratio (OR) = 13.33, P < 0.001) and sepsis (OR = 11.37, P = 0.026). There was no significant difference in primary outcomes with irrigation. Patients who received irrigation had a longer length of stay (7.59 vs. 4.69 days, P = 0.001) as did those who received an intraoperative drain (7.61 vs. 5.33 days, P = 0.01). Conclusions: In this study, irrigation did not change the OR of sepsis and postoperative abscess. However, placement of an intraoperative drain increased both the rates of sepsis and postoperative abscesses, indicating possible increase in postoperative complications with intraoperative drains when compared with no drains. J Curr Surg. 2019;9(2-3):17-21 doi: https://doi.org/10.14740/jcs385
背景:在复杂阑尾炎阑尾切除术中进行冲洗和/或术中放置腹膜引流管的做法目前存在争议。本研究旨在描述术中引流管放置和/或冲洗与复杂阑尾炎患者预后之间的关系。方法:对225例急性复杂阑尾炎患者进行回顾性研究,阑尾炎定义为穿孔或坏疽。主要结局被定义为术后脓肿或脓毒症的存在,而次要结局被测量为住院时间。结果:术中放置引流管的患者发生术后脓肿(优势比(OR) = 13.33, P < 0.001)和脓毒症(OR = 11.37, P = 0.026)的风险增加。冲洗组的主要结局无显著差异。接受冲洗的患者住院时间较长(7.59天对4.69天,P = 0.001),术中引流的患者住院时间较长(7.61天对5.33天,P = 0.01)。结论:在本研究中,冲洗并没有改变脓毒症和术后脓肿的OR。然而,术中引流管的放置增加了脓毒症和术后脓肿的发生率,表明术中引流管与无引流管相比可能增加了术后并发症。中华外科杂志,2019;9(2-3):17-21 doi: https://doi.org/10.14740/jcs385
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引用次数: 1
A Case Report of Successful Treatment of Mammary Myofibromyoblastoma in a Male Patient 男性乳腺肌纤维母细胞瘤成功治疗1例报告
Pub Date : 2019-09-16 DOI: 10.14740/jcs340
O. Abdalla, A. Chitnis, Banan Omer, M. Elhadi, M. O. Karim, S. Sabri
Myofibroblastoma (MFB) is an extremely rare benign tumor that can arise in various organs, but commonly in the breast. Albeit it is a benign tumor, the diagnosis is frequently challenging with insurmountable difficulties as it might be erroneously diagnosed as a malignancy. Herein we are reporting a large-sized MFB presented as a non-tender, firm mass which interestingly was adherent to the skin and was initially thought as cancer. The patient underwent a wide local excision and histology confirmed MFB, and had no evidence of recurrence up to 8 months post-operatively. J Curr Surg. 2019;9(2-3):26-28 doi: https://doi.org/10.14740/jcs340
肌成纤维细胞瘤(MFB)是一种非常罕见的良性肿瘤,可发生在各种器官,但常见于乳房。虽然它是良性肿瘤,但诊断往往具有难以克服的困难,因为它可能被错误地诊断为恶性肿瘤。在此,我们报告一例大型MFB,表现为非触痛、坚硬的肿块,有趣的是,它粘附在皮肤上,最初被认为是癌症。患者接受了广泛的局部切除,组织学证实了MFB,术后8个月无复发迹象。中华外科杂志,2019;9(2-3):26-28 doi: https://doi.org/10.14740/jcs340
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引用次数: 0
Proximal Radius Ewing’s Sarcoma Resection Followed by Migration of the Proximal Radius: Report of Two Cases 桡骨近端尤文氏肉瘤切除后桡骨近端移位2例报告
Pub Date : 2019-09-16 DOI: 10.14740/jcs383
W. Al-Juhani, Mohammed Benmeakel
We present two young patients who developed Ewing’s sarcoma in the proximal radius, managed surgically by resection and no reconstruction with K-wire fixation of the distal radioulnar joint for 6 weeks. Following surgery, both patients developed proximal radius migration with subluxation, which caused the patients to complain about deformation. Proximal radius migration with subluxation is well documented in trauma cases, although they were not described in orthopedic oncology since reconstruction was the classic management for such cases. Our results support the decision of reconstructing the proximal radius after resection in order for better functional outcome and stability. J Curr Surg. 2019;9(2-3):32-37 doi: https://doi.org/10.14740/jcs383
我们报告了两名在桡骨近端发生尤文氏肉瘤的年轻患者,通过手术切除和不重建,用k线固定远端尺桡关节6周。手术后,两名患者均出现桡骨近端移位伴半脱位,导致患者主诉变形。桡骨近端移位伴半脱位在创伤病例中有很好的文献记载,尽管在骨科肿瘤学中没有描述,因为重建是这类病例的经典治疗方法。我们的结果支持切除后重建桡骨近端以获得更好的功能结果和稳定性的决定。中华外科杂志,2019;9(2-3):32-37 doi: https://doi.org/10.14740/jcs383
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引用次数: 1
Realignment of a Surgical Gastric Sleeve Using the Apollo Endoscopic Suturing Platform in a Patient With Postoperative Persistent Nausea and Vomiting 应用Apollo内镜缝合平台对术后持续恶心呕吐患者的手术胃套管进行调整
Pub Date : 2019-09-16 DOI: 10.14740/jcs380
A. Hillan, Mujtaba Mohamed, Kadhim Al-Banaa, Diana Curras-Martin, S. Gorcey, Mohammad A. Hossain
Laparoscopic sleeve gastrectomy is a restrictive procedure without the malabsorptive component of gastric bypass or duodenal switch. Reported common complications include bleeding, stenosis, misalignment, staple line leaks, and severe regurgitate symptoms. This case represents an uncommon complication characterized by gastroesophageal junction outflow obstruction due to redundant tissue from post-surgical change in the fundus. Repair with complete resolution of symptoms was achieved by performing endoscopy gastroplasty with the Apollo overstitch suturing system. J Curr Surg. 2019;9(2-3):29-31 doi: https://doi.org/10.14740/jcs380
腹腔镜袖胃切除术是一种限制性手术,没有胃旁路或十二指肠开关的吸收不良成分。常见的并发症包括出血、狭窄、排列错位、钉线泄漏和严重的反流症状。本病例是一罕见的并发症,其特征是胃食管交界流出部因术后眼底改变所造成的多余组织阻塞。修复与完全解决的症状是通过执行内窥镜胃成形术与阿波罗缝合系统。中华外科杂志,2019;9(2-3):29-31 doi: https://doi.org/10.14740/jcs380
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引用次数: 0
A Rare Presentation of Cecal Diverticulitis in a Patient With Cystic Fibrosis 囊性纤维化患者罕见的盲肠憩室炎
Pub Date : 2019-02-21 DOI: 10.14740/JCS374
Manrique A. Guerrero, Mariam Selevany, M. Sridhar, P. Hanna, Jamshed Zuberi
Cecal diverticulitis (CD) is a rarely seen and studied condition in American medicine. CD presents in a manner that is almost clinically indistinguishable from acute appendicitis. Both CD and acute appendicitis present with exceedingly similar symptoms including, but not limited to, right lower quadrant (RLQ) pain, fever, and vomiting. The diagnosis of CD is usually made during an operation and is seldom caught preoperatively. Although a fair number of CD cases have been reported since its discovery, only a handful of patients concurrently had a history of cystic fibrosis (CF). We report a rare case of CD that was initially believed to be appendicitis in a male patient with CF. Intraoperatively, a diagnosis of CD was reached due to identification of a single diverticulum in the cecal region with inflammatory changes consistent with microperforation. A partial cecectomy was performed and the patient was discharged 4 days later with resolution of symptoms. J Curr Surg. 2019;9(1):13-16 doi: https://doi.org/10.14740/jcs374
盲肠憩室炎(CD)在美国医学中是一种罕见的疾病。乳糜泻的表现在临床上几乎与急性阑尾炎难以区分。乳糜泻和急性阑尾炎都表现出非常相似的症状,包括但不限于右下腹部疼痛、发烧和呕吐。乳糜泻的诊断通常在手术中进行,很少在术前发现。虽然自发现以来已有相当数量的乳糜泻病例报道,但只有少数患者同时有囊性纤维化(CF)史。我们报告一例罕见的乳糜泄病例,最初被认为是男性CF患者的阑尾炎。术中,由于在盲肠区发现了一个憩室,炎症变化与微穿孔一致,因此得出了乳糜泄的诊断。患者行部分盲肠切除术,4天后症状缓解出院。中华外科杂志,2019;9(1):13-16 doi: https://doi.org/10.14740/jcs374
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引用次数: 0
Treatment Challenges of Primary Acinic Cell Carcinoma of the Breast 原发性乳腺腺泡细胞癌的治疗挑战
Pub Date : 2019-02-21 DOI: 10.14740/jcs373
Sundus Abbasi, L. Hopkins
We present a rare case of primary acinic carcinoma in the breast, which is almost always associated with salivary glands. We will discuss the multidisplinary approach to treatment, highlighting the role of chemotherapy and radiation. Additionally, this tumor was seen on magnetic resonance imaging (MRI), which is not a readily used diagnostic test for breast disease, emphasizing its diagnostic sensitivity in these patients. J Curr Surg. 2019;9(1):11-12 doi: https://doi.org/10.14740/jcs373
我们报告一例罕见的乳腺原发性腺泡癌,其几乎总是与唾液腺相关。我们将讨论多学科的治疗方法,强调化疗和放疗的作用。此外,该肿瘤在磁共振成像(MRI)上被发现,这不是一种容易用于乳腺疾病的诊断测试,强调了其在这些患者中的诊断敏感性。中华外科杂志,2019;9(1):11-12 doi: https://doi.org/10.14740/jcs373
{"title":"Treatment Challenges of Primary Acinic Cell Carcinoma of the Breast","authors":"Sundus Abbasi, L. Hopkins","doi":"10.14740/jcs373","DOIUrl":"https://doi.org/10.14740/jcs373","url":null,"abstract":"We present a rare case of primary acinic carcinoma in the breast, which is almost always associated with salivary glands. We will discuss the multidisplinary approach to treatment, highlighting the role of chemotherapy and radiation. Additionally, this tumor was seen on magnetic resonance imaging (MRI), which is not a readily used diagnostic test for breast disease, emphasizing its diagnostic sensitivity in these patients. J Curr Surg. 2019;9(1):11-12 doi: https://doi.org/10.14740/jcs373","PeriodicalId":93115,"journal":{"name":"Journal of current surgery","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80360443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Torsion of the Vermiform Appendix Secondary to Mucinous Cystadenoma 粘液囊腺瘤继发于蚓状阑尾的扭转
Pub Date : 2019-01-22 DOI: 10.14740/JCS358
Sundus Abbasi, M. Lopez-Viego
Torsion of the vermiform appendix (TMA) is a rare entity that is often clinically indistinguishable from acute appendicitis. Primary torsion results from anatomical abnormalities and secondary torsion results from obstructive pathologic processes such as mucinous cystadenomas. Torsion secondary to a mucinous cystadenoma is found in 0.2-0.3% of appendectomies. The diagnosis of TVA is difficult, requiring histological confirmation after surgical intervention. We present a rare case of TVA in a 35-year-old woman with abdominal pain for 2 days. J Curr Surg. 2019;9(1):9-10 doi: https://doi.org/10.14740/jcs358
蚓状阑尾扭转(TMA)是一种罕见的实体,通常在临床上与急性阑尾炎难以区分。原发性扭转由解剖异常引起,继发性扭转由粘液囊腺瘤等梗阻性病理过程引起。继发于粘液囊腺瘤的扭转在0.2% -0.3%的阑尾切除术中发现。TVA的诊断是困难的,需要手术后的组织学证实。我们报告一例罕见的TVA病例,患者为35岁女性,腹痛2天。中华外科杂志,2019;9(1):9-10 doi: https://doi.org/10.14740/jcs358
{"title":"Torsion of the Vermiform Appendix Secondary to Mucinous Cystadenoma","authors":"Sundus Abbasi, M. Lopez-Viego","doi":"10.14740/JCS358","DOIUrl":"https://doi.org/10.14740/JCS358","url":null,"abstract":"Torsion of the vermiform appendix (TMA) is a rare entity that is often clinically indistinguishable from acute appendicitis. Primary torsion results from anatomical abnormalities and secondary torsion results from obstructive pathologic processes such as mucinous cystadenomas. Torsion secondary to a mucinous cystadenoma is found in 0.2-0.3% of appendectomies. The diagnosis of TVA is difficult, requiring histological confirmation after surgical intervention. We present a rare case of TVA in a 35-year-old woman with abdominal pain for 2 days. J Curr Surg. 2019;9(1):9-10 doi: https://doi.org/10.14740/jcs358","PeriodicalId":93115,"journal":{"name":"Journal of current surgery","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80926675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of current surgery
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