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Archives of orthopedics and rheumatology最新文献

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Deep Vein Thrombosis (DVT) in an Operated Sub Trochanteric Fracture Femur 深静脉血栓形成(DVT)在股骨粗隆下骨折手术
Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0101006
N. Dhaniwala, Malhar Jadhav, Venkatesh Dasari, Vrushabh U. Kumbhare
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引用次数: 0
Lower Limb Bone Shortened by 10 Cm and Replantation Extension in Children 儿童下肢骨缩短10cm及再植延长
Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0101005
Changliang Ou, Xincheng Tang, Yonggen Zou, Xuchao Luo
Children complex limb disconnection, most of them undergo amputation after evaluate MESS score and then mounting prosthesis. In this case,the mess score of right calf amputation is above 7, and we adopted short 10cm replantation. After the limb replantation survived smoothly, we performed bone lengthening by Ilizarov technique. After 4 years follow-up, satisfactory clinical results have been obtained.
小儿复杂肢体断连,多在评估MESS评分后再安装义肢进行截肢。本例右小腿截肢的mess评分在7分以上,我们采用短10cm再植。肢体再植顺利后,采用Ilizarov技术行骨延长术。经过4年的随访,临床效果满意。
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引用次数: 1
Acute Febrile Polyarthritis Revealing very Late-Onset Behcet's Disease 显示迟发性白塞病的急性发热性多关节炎
Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0102001
S. Bouomrani, M. Nefoussi
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引用次数: 0
Drug Development in Unani System of Medicine: Reverse Pharmacological Approach Unani医学系统中的药物开发:反向药理学方法
Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0102002
Imtiyaz Ahmad Mir, G. Sofi, S. Mehfooz, Khadija Abdul Hafeez, Ghousia islam
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引用次数: 0
Minimally Invasive Spine Osteosynthesis (MISO) Technique Versus Traditional and Paraspinal Posterior Open Approaches for Treatment of Thoracolumbar Spine Fractures 微创脊柱植骨术与传统椎旁后路开放入路治疗胸腰椎骨折的比较
Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0102003
Bahaa Ali kornah Hesham, Mohamed safwat Mohamed, Abdelaziz Mohamed, Ibrahim abuelesoud Tharwat, A. Ghany, Nagy Saleem, Mohamed Abdel-AAl
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引用次数: 0
Assesment of Common Exon 10 MEFV Gene Mutations in Patients with Refractory Rheumatoid Arthritis 难治性类风湿关节炎患者常见外显子10 MEFV基因突变的评估
Pub Date : 2018-01-01 DOI: 10.22259/2639-3654.0101001
A. Mirzaei, S. Kolahi, Fatima Pashaei-Asl, S. Esmaeili
Objective: Rheumatoid arthritis (RA) is a common chronic inflammatory arthritis with many flare ups in some patients. New studies showed the importance of Mediterranean fever gene mutations in certain inflammatory conditions. We investigated molecular mutation in exon 10 of MEFV gene in patients with refractory RA and healthy individuals as a control group in North-West of Iran. Methods: We conducted thirty four patients with refractory RA and fifty healthy controls in this study. Their DNA samples were analyzed with specific primers, standard PCR and Sequencing techniques. We studied the most common exon 10 variations on MEFV gene which include; M680I, M694V, M694I and V726A. Results: The mean ages of patients with refractory RA were 43.8 ± 7.7 years and disease duration was 49.8 ± 7.36 months. The mean of DAS 28 (Disease Activity score) of patients with refractory RA was about 4.2 ± 0.51. The mean ages of healthy control cases were 45.4 ± 8.27 years. The result of DNA sequencing showed no mutations in common exon 10 variations of MEFV gene in both groups. Conclusion: According to the result, we found no association between severity of RA and common exon 10 MEFV gene mutations.
目的:类风湿关节炎(RA)是一种常见的慢性炎症性关节炎,在一些患者中有许多突然发作。新的研究表明地中海热基因突变在某些炎症条件下的重要性。我们研究了伊朗西北部难治性RA患者和健康人MEFV基因外显子10的分子突变作为对照组。方法:选取34例难治性RA患者和50例健康对照。采用特异性引物、标准PCR和测序技术对其DNA样本进行分析。我们研究了MEFV基因最常见的外显子10变异,包括;M680I, M694V, M694I和V726A。结果:顽固性RA患者平均年龄43.8±7.7岁,病程49.8±7.36个月。难治性RA患者的DAS 28(疾病活动评分)平均值约为4.2±0.51。健康对照的平均年龄为45.4±8.27岁。DNA测序结果显示,两组MEFV基因共同外显子10变异均未发生突变。结论:根据结果,我们发现RA的严重程度与常见外显子10 MEFV基因突变无关。
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引用次数: 0
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Archives of orthopedics and rheumatology
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