Journal of dentistry and dental medicine最新文献

{"title":"Gene-Based Association Mapping for Dental Caries in The GENEVA Consortium.","authors":"Yueyao Wang,&nbsp;Dipankar Bandyopadhyay,&nbsp;John R Shaffer,&nbsp;Xiaowei Wu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Dental caries is a multifactorial disease with high prevalence in both children and adults. Recent genome-wide association studies (GWASs) have revealed that genetic factors play an important role in caries incidence. However, existing methods are not sufficient to identify caries-associated genes, due to the complex correlation structure of caries GWAS data, and lack of appropriate summarization at the gene level. This paper attempts to address that by analyzing data from the Gene, Environment Association Studies (GENEVA) consortium.</p><p><strong>Methods: </strong>We investigated gene-based genetic associations for dental caries based on genome-wide data derived from the GENEVA database, with adjustment to covariates, linkage disequilibrium among single-nucleotide polymorphisms, and family relations, in sampled individuals.</p><p><strong>Results: </strong>Several suggestive genes were identified, in which some of them have been previously found to have potential biological functions on cariogenesis.</p><p><strong>Conclusions: </strong>By comparing the gene sets identified from gene-based and SNP-based association testing methods, we found a non-negligible overlap, which indicates that our gene-based analysis can provide substantial supplement to the traditional GWAS analysis.</p>","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39521032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cranial Deformity, Reconstruction of Cranium","authors":"Israa Anwar Abd al-Hameed, A. Mahmood, Yasir Adil Taka","doi":"10.31021/JDDM.20192130","DOIUrl":"https://doi.org/10.31021/JDDM.20192130","url":null,"abstract":"Cranioplasty is defined as the surgical repair of acquired defects or congenital deformities of the cranium. It is performed mainly for anatomical reconstruction, brain protection, and cosmetics, but evidence has shown that there is also improvement of brain physiology. The aims of this paper are to describe a technique to fabricate polymethylmethacrylate prostheses by hand during operation and at the same time describe the surgical outcomes of this procedure. Between the years 2007 and 2011, 20 patients were complaining from cranial bone defect due to many causes underwent cranioplasty operation in Mosul Medical Center/IRAQ for reconstructed the defect using the polymethylmethacrylate that fabricated by hand during the operation. The operations were done by the same maxillofacial surgeon with different neurosurgeons. Age of patients extended from 14 years to 42 years with mean 33.2 years. The main cause of cranial defect was trauma resulting from missiles injuries that involved 14 patients and formed 70%. During the follow-up, all patients were satisfied with the cosmetic result and no revision for cosmetic reasons was required. One patient developed infection in one of stainless steel wire postoperatively that controlled and resolved the problem by remove this wire only. Thus, the implanted material was well tolerated in all cases. The majority of patients were males while the most common cause of cranial defect was due to traumatic cranial injury by missiles injuries. Infection, being the most feared complication of allograft implants, but there was a very low rate with the technique described in this paper. This technique is quick and easy to perform, and provide a cheap and safe way produces a strong implant very good cosmetic. *Corresponding author: Israa Anwar Abd al-Hameed, BDS, MSc Dentistry College Mosul University Mosul, Iraq E-mail: amertaqa@hotmail.com Citation: Abd al-Hameed IA, Mahmood AS, Taka YA. Cranial deformity, Reconstruction of cranium. J Dents Dent Med. 2019 Mar;2(1):130 Copyright: © 2019 Abd al-Hameed IA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 international License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 1Dentistry College, Mosul University, Mosul, Iraq 2Department of Maxillofacial Surgery, AL-Jumhory Teaching Hospital, Mosul, Iraq 3Department of Surgery, Mosul College of Medicine, Mosul University, Mosul, Iraq Israa Anwar Abd al-Hameed1* Ali Salim Mahmood2 Yasir Adil Taka3","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44484890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Microbiology and Antibiotic Sensitivity in Maxillo-mandibular Infections","authors":"N. Sulaiman, S. A. Issa","doi":"10.31021/JDDM.20192129","DOIUrl":"https://doi.org/10.31021/JDDM.20192129","url":null,"abstract":"Oral cavity is important functional structure of the body, like other parts of the body it contains micro bacteria as a commensally structures. Several species of bacteria present in the mouth that exploit the circumstances of human immunity and oral hygiene to cause infections which can spread to the facial region and neck to the rest of the body and lead to serious outcome. Background: Determine most common bacterial microorganisms and antibiotic sensitivity of maxillomandibular infections. Materials and Methods: A descriptive study was carried out on 45 patients with different forms of maxillomandibular infections, data regarding age, gender, presenting signs were collected through history, clinical examination and radiographs, incision and drainage with swab sample for culture and sensitivity test was done. Results: Patients with maxillomandibular infections showed a male to female ratio of 1:1.25 The mean age was 33 years. Most of the patients were in the 4th decade 27% of life, most common isolated microorganism was Streptococcus pyogene 59%, antibiotics with greatest sensitivity were Netilmicin, Cefoperazone and Rifampicin 91%. *Corresponding author: Noor A Sulaiman, FIBMS(MF) Department of Oral and Maxillofacial surgery College of Dentistry, University of Mosul Mosul, Iraq E-mail: amertaqa@hotmail.com Citation: Sulaiman NA, Issa SA. Bacterial microbiology and antibiotic sensitivity in maxillo-mandibular infections. J Dents Dent Med. 2019 Mar;2(1):129 Copyright: © 2019 Sulaiman NA, et al, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 international License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 1Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Mosul, Mosul, Iraq 2Consultant Maxillofacial Surgeon, Medical City, Baghdad, Iraq Noor A Sulaiman1* Sabah A Issa2","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45175217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Manifestations and Surgical Treatment of Craniosynostosis in Mosul City�Iraq","authors":"Israa Anwar Abd al-Hameed, Y. Taha, A. Mahmood","doi":"10.31021/JDDM.20192128","DOIUrl":"https://doi.org/10.31021/JDDM.20192128","url":null,"abstract":"Introduction: Craniosynostosis is a condition in which one or more of the fibrous sutures in an infant skull prematurely fuses by turning into bone. Aim: Evaluate the clinical manifestations of craniosynostosis, imaging and surgical treatment with their complications. Materials and Methods: The study comprised twenty one patients complaining from craniofacial deformity. The patients evaluated by recording the medical history, clinical examination and diagnosed by imaging that included a plain X-ray and computed tomography. The goal of surgery is to open the fused sutures, reshape the head and allow for normal brain and skull growth. According to the type of material that used to fixate the cranial bones, the patients divided into 3 groups, Group A: Titanium plate and stainless steel wire; Group B: Stainless wire; Group C: Absorbable suture. Results: The clinical examination showed cranial bones deformity in all patients while 4 patients involved by papilloedema. The plain X-ray for the skull diagnosed 4 cases by showed beaten copper appearance, while the computed tomography gave excellent evaluation for all cases. The nonsyndromic craniosynostosis formed (90.4%) and coronal suture involvement formed (61.9%). The follow-up showed that the group C had more cosmetic improvement and more comfortable than group A and B, and there were 4 patients in group A and 2 patients in group B complained from extracranial prominent of plates and wire. Discussion: The advantages of absorbable suture included lower costs, speed of application, and absence of translocation. Conclusion: The most clinical manifestations were cranial deformity while visual deterioration was often late manifestations. The computed tomography scan represents the gold standard evaluation for craniosynostosis. The use absorbable suture in bone fixation showed more cosmetic improvement and more comfortable to the patients with low complication rate. *Corresponding author: Israa Anwar Abd al-Hameed, BDS, MSc Department of Periodontology, School Dentistry College, Mosul University Mosul, Iraq E-mail: amertaqa@hotmail.com Citation: Abd al-Hameed IA, Taha YA, Mahmood AS. Clinical manifestations and surgical treatment of craniosynostosis in Mosul city–Iraq. J Dents Dent Med. 2019 Mar;2(1):128 Copyright: © 2019 Abd al-Hameed IA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 international License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 1Dentistry College, Mosul University, Mosul, Iraq 2Department of Surgery, Mosul College of Medicine, Mosul University, Mosul, Iraq 3Department of Maxillofacial Surgery, AL-Jumhory Teaching Hospital, Mosul, Iraq Israa Anwar Abd al-Hameed1* Yasir Adil Taha2 Ali Salim Mahmood3","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47129791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consequence of Bisphosphonate on Dental Implant Success in Osteoporotic Females","authors":"R. Al-Rawee, A. Saeed, B. Tawfeeq","doi":"10.31021/JDDM.20192127","DOIUrl":"https://doi.org/10.31021/JDDM.20192127","url":null,"abstract":"Objective: To evaluate the effect of Bisphosphonate on Dental Implant failure rate in osteoporotic female patients. Patients and Method: Fifteen osteoporotic female patients underwent surgery to place 72 fixtures, in upper jaw, loaded completely within 4 months. Patients take Alendronate tablet 10 mg once daily for 8 months, 2 months preoperative and 6 months postoperative. Compares with healthy females underwent implant surgery too. Results: Six dental implants were failed at the time of second step surgery (Gingival Former Step), with no other complication faced by the patients whether related to drug used or to surgery. Three fixtures were failed in healthy females. Statistically no significant differences in the effect of bisphosphonate on dental implant failure. Discussion: Patients who take oral Bisphosphonate are no more at risk of implant failure than normal patients with no drug use. *Corresponding author: Rawaa Y Al-Rawee BDS, MSc, MOMSRCPS Glasgow (Ph.D.MaxFacs) Department of Oral and Maxillofacial Surgery Al-Salam Teaching Hospital Al-Sukar, Mosul, Iraq Tel: 009647726438648 E-mail: dr.rawarawi@yahoo.com Citation: Al-Rawee RY, Saeed AM, Tawfeeq BAG. Consequence of Bisphosphonate on Dental Implant Success in Osteoporotic Females. J Dents Dent Med. 2019 Mar;2(1):127 Copyright: © 2019 Al-Rawee RY, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 international License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 1Department of Oral and Maxillofacial Surgery, Al-Salam Teaching Hospital, Mosul, Iraq 2Department of Oral and Maxillofacial Surgery, Al-Gemhoory Teaching Hospital, Mosul, Iraq Rawaa Y Al-Rawee1* Ali Mohammad Saeed2 Bashar Abdul-Ghani Tawfeeq1","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46810563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Selective Medium for the Isolation of Rothia aeria, Which Is an Inhabitant of the Human Oral Cavity","authors":"Taira Kobayashi, Satoshi Uchibori, Osamu Tsuzukibash, Chihiro Uezato, M. Fuchigami, Haruhiko Goto, H. Tamaki, Koji Umezawa, Takaaki Tanaka, M. Ohta","doi":"10.31021/jddm.20181124","DOIUrl":"https://doi.org/10.31021/jddm.20181124","url":null,"abstract":"Roth aeria, Rothia dentocariosa, and Rothia mucilaginosa are isolated from the human oral cavity. Among them, R. aeria can cause severe systemic infection diseases (e.g., bronchitis, endocarditis, pneumonia, and sepsis). However, the veritable prevalence of this organism in the human oral cavity has not ever been known. Thus, the selective medium for the isolation and quantification of R. aeria is necessary to assess the prevalence of this organism, and to diagnose various R. aeria infection diseases. To investigate R. aeria distribution in oral cavities, a novel selective medium (RAESM) was developed for isolating and quantifying R. aeria. RAESM consists of sodium gluconate, tryptone, meat extract, sodium fluoride, acriflavin neutral, fosfomycin, lincomycin, colistin, aztreonam, and agar. Polymerase chain reaction (PCR) primers were designed based on partial sequences of the 16S rDNA genes of R. aeria. The percentage of R. aeria in saliva samples collected from 20 subjects was examined. Moreover, we examined the antibiotic susceptibility of thirty isolates from six subjects. The average growth recovery of R. aeria on RAESM was 96.6% compared with that on Brain Heart Infusion supplemented with Yeast Extract (BHI-Y) agar. Growth of other representative oral bacteria, including other Rothia species, was remarkably inhibited on the selective medium. The PCR primers reacted to R. aeria and did not react to other Rothia species or representative oral bacteria. R. aeria was detected as 1.0% of the total bacteria, 5.9×107CFU/ml, on BHI-Y agar in the oral cavities of all subjects. R. aeria isolates obtained in this study were susceptible to most antibiotics; however R. aeria isolates from one subject were highly resistant to erythromycin, lincomycin, and clindamycin. R. aeria may be a part of the normal flora in the human oral cavities. A novel selective medium, RAESM, was useful for isolating R. aeria. Moreover, it was indicated that RAESM was useful for diagnosing R. aeria infections.","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49281870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Child Anesthesia be Harmful?","authors":"M. Karimi","doi":"10.31021/JDDM.20181123","DOIUrl":"https://doi.org/10.31021/JDDM.20181123","url":null,"abstract":"","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44351029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The First Time in","authors":"Nirmala Svsg, S. Degala, Minor Babu M.S","doi":"10.31021/JDDM.20181122","DOIUrl":"https://doi.org/10.31021/JDDM.20181122","url":null,"abstract":"• Teach in online master’s and graduate certificate program. Courses are 8-weeks in length, teach 10 courses annually. • Responsible for curriculum planning, course design, continuous development of instructional practice, and maintaining an updated knowledge of college student development and higher education. • Courses developed and taught: o EDG 6362 College Student Development o EDG 6366 Student Affairs and Administrative Services o EDG 6367 Foundation of Academic Advising o EDG 6361 American Higher Education o EDSD 6302 Advising for College Transitions o EDSD 6304 Program Administration and Assessment o EDG 6305 Legal and Ethical Principles o EDG 6364 Issues in Higher Education • Other courses taught: o EDG 6324 Career & Occupational Counseling o EDG 6301 Social and Cultural Influences o EDG 6369 Assessment of Student Outcomes o EDG 6398 Capstone in Student Development","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43852728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The First Time in","authors":"X. Riaud","doi":"10.31021/JDDM.20181121","DOIUrl":"https://doi.org/10.31021/JDDM.20181121","url":null,"abstract":"","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43992604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indirect Bonding Procedures in Orthodontics - A Review","authors":"P. Aggarwal, Rajni Aggarwal","doi":"10.31021/jddm.20181120","DOIUrl":"https://doi.org/10.31021/jddm.20181120","url":null,"abstract":"Indirect bonding (IDB) has been in orthodontic practice for more than 35 years. But still, most of the clinicians use direct bonding procedures. The main reason for this may be technique sensitivity and requirement of extra laboratory procedures, increasing the cost of the treatment. Many researchers have tried their methods to describe the indirect bonding procedures so that it can reduce the chair side time required for complete appliance placement with more precise bracket positioning. Moreover, the IDB procedures provide more patient comfort. Many techniques have been described in the article to simplify the IDB procedures. *Corresponding author: Dr. Aggarwal P, DB.D.S., M.D.S. Orthodontics and Dentofacial Orthopedics Advanced Dental Care Centre, Peer Khana Road, Khanna-141401, Punjab, India E-mail: panchamaggarwal@yahoo.com Citation: Aggarwal P, Aggarwal R. Indirect Bonding Procedures in Orthodontics A Review. J Dents Dent Med. 2018 Aug;1(4):120 Copyright: © 2018 Aggarwal P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 international License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 1*Orthodontics and Dentofacial Orthopedics, Advanced Dental Care Centre, Punjab, India 2Advanced Dental Care Centre, Punjab, India Pancham Aggarwal1* Rajni Aggarwal2","PeriodicalId":93308,"journal":{"name":"Journal of dentistry and dental medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49422612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}