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A rare presentation of isolated sixth nerve palsy as dolichoectasia of vertebral artery 罕见的孤立性第六神经麻痹表现为椎动脉粘连扩张
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00396
Li Juan
Vertebrobasilar dolichoectasia is a condition where the vertebral arteries are dilated, elongated and distorted, causing significant deterioration of tunica intima. The most common causes of sixth nerve palsy include infection, stroke, brain tumour and injury. We reported a case of a 56-year-old man with underlying of diabetes mellitus and hypertension who presented with diplopia over his left gaze. There are no other associated neurology signs. Computed tomography (CT) brain showed well-defined hypodensities at right lentiform nucleus and brain magnetic resonance angiography (MRA) showed impingement of V4 vertebral artery to anterior lower pons near midline which is the exit of the left abducens nerve from the pons. This case illustrated the importance to investigate thoroughly the causes of sixth cranial nerve palsy.
椎基底动脉过宽症是椎动脉扩张、延长和扭曲的一种情况,导致膜内膜明显恶化。第六神经麻痹最常见的原因包括感染、中风、脑肿瘤和损伤。我们报告一例56岁男性糖尿病和高血压的潜在谁提出复视在他的左凝视。没有其他相关的神经学症状。脑CT示右侧晶状体核明显低密度,脑磁共振血管造影示V4椎动脉与脑桥前下段中线附近有撞击,这是左展神经与脑桥的出口。本病例说明深入探讨第六脑神经麻痹病因的重要性。
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引用次数: 0
Evaluate the delay in the management of acute abdomen at the Yaounde central hospital: a prospective cohort study 评估雅温得中心医院急腹症治疗的延迟:一项前瞻性队列研究
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00404
Joseph Cyrille Chopkeng Ngoumfe
Background: Early surgical treatment remains the first factor of good prognosis for the management of acute abdominal diseases. The aim of this study was to evaluate the delay in the management of these pathologies in our context. Material and methods: We conducted a prospective cross-sectional study at the Yaoundé Central Hospital (HCY) over 7 months. All patients over 15 years of age presenting with an acute non-traumatic digestive surgical abdomen were included. The follow-up was done during the entire hospital stay of the patients. The dates and times of the different stages of management were recorded. Results: We collected 63 patients, 37 men, with a sex ratio M/F of 1.42. The mean age was 41.06±18 years. The mean time between arrival in the emergency room and the indication for surgery was 16.9 hours. Acute generalized peritonitis (n=26) was the most common diagnosis with 41.3% of cases. The average time between the indication for surgery and the availability of the surgical kit was 19 hours. The average time between the availability of the operating kit and the start of the surgical procedure was 6.2 hours. The complication rate was 33.3%. The mortality rate was 15.9%. Conclusion: Our delays in the management of acute abdomens are relatively long. A better organisation of the system and continuous training of the medical staff of peripheral hospitals would improve the prognosis of our patients.
背景:早期手术治疗仍然是急性腹部疾病治疗预后良好的首要因素。本研究的目的是评估在我们的背景下这些病理的管理延迟。材料和方法:我们在雅温得中心医院(HCY)进行了为期7个月的前瞻性横断面研究。所有年龄在15岁以上的急性非创伤性消化手术腹部的患者都被包括在内。随访是在患者整个住院期间进行的。记录不同管理阶段的日期和时间。结果:共收集63例患者,其中男性37例,性别比M/F为1.42。平均年龄41.06±18岁。从到达急诊室到手术指征的平均时间为16.9小时。急性广泛性腹膜炎(26例)是最常见的诊断,占41.3%。从手术指征到获得手术包的平均时间为19小时。从获得手术包到开始手术的平均时间为6.2小时。并发症发生率为33.3%。死亡率为15.9%。结论:急腹症的治疗延误时间较长。通过对周边医院医护人员的持续培训和系统的完善,可以改善患者的预后。
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引用次数: 0
A rare case presentation of acute myo-pericarditis in a patient with lupus flare 一例罕见的急性心包炎患者狼疮发作
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00374
L. Caraballo
Systemic lupus erythematosus (SLE) is a chronic, multisystem, inflammatory disorder of autoimmune etiology of unknown cause. Cardiac involvement during systemic lupus erythematosus (SLE) may include the pericardium, myocardium, valvular disease, including Libman-Sacks endocarditis, and coronary arteries. Myocarditis is a severe unusual feature most common in African-American that can be asymptomatic with a prevalence of 8-25% in patients with systemic lupus erythematosus. Acute myo-pericarditis with subsequent heart failure is a life threatening complication of SLE that needs to get recognized early to prevent mortality to the patient. Steroids is the first line therapy in patients with acute myopericarditis. Here we present a rare case of SLE flare presenting as Acute myopericarditis.
系统性红斑狼疮(SLE)是一种慢性,多系统,炎症性疾病的自身免疫性病因不明。系统性红斑狼疮(SLE)的心脏受累可能包括心包、心肌、瓣膜疾病(包括Libman-Sacks心内膜炎)和冠状动脉。心肌炎是一种严重的不寻常的特征,最常见于非洲裔美国人,在系统性红斑狼疮患者中可无症状,患病率为8-25%。急性心包炎并发心力衰竭是SLE的一种危及生命的并发症,需要及早发现以防止患者死亡。类固醇是急性心包炎患者的一线治疗。我们在此报告一例罕见的SLE发作,表现为急性心肌炎。
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引用次数: 0
Robot-assisted partial nephrectomy and nephrolithotomy for multiple lower pole calculi in an atrophic kidney 机器人辅助部分肾切除术和肾镜取石术治疗萎缩性肾多发肾下极结石
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00376
J. Tay
Open renal stone surgery has been largely replaced by retrograde intrarenal surgery (RIRS), percutaneous nephrolithotomy (PCNL) and extracorporeal shockwave lithotripsy (ESWL). However, when these methods fail to remove a stone or there are certain contraindications, such as pregnancy and obesity, laparoscopic, robotic or open surgery may still be indicated. In fact, robotic surgery has been increasingly used by urologists for different benign indications including chronic pyelonephritis, neglected ureteropelvic junction obstruction and renal tuberculosis. This article describes a case of robotic-assisted partial nephrectomy and nephrolithotomy for a large amount of small lithiasis in a non-functioning lower pole after failed stone clearance with a single use Boston ureteroscope owing to non-accessibility.
开腹肾结石手术已被逆行肾内手术(RIRS)、经皮肾镜取石术(PCNL)和体外冲击波碎石术(ESWL)所取代。然而,当这些方法不能取出结石或有某些禁忌症时,如怀孕和肥胖,腹腔镜、机器人或开放手术仍可能需要。事实上,泌尿科医生越来越多地使用机器人手术来治疗各种良性适应症,包括慢性肾盂肾炎、被忽视的肾盂输尿管连接处梗阻和肾结核。这篇文章描述了一例机器人辅助的部分肾切除术和肾镜取石术,用于在单次使用波士顿输尿管镜由于无法到达而无法清除结石后的下极的大量小结石。
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引用次数: 0
Tau peptide signals are seen in Parkinson subjects by Broderick Probe® sensors 通过Broderick Probe®传感器观察帕金森患者的Tau肽信号
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00380
P. Broderick
This “short but sweet” clinical paper is about a next generation “uptick” nanotechnology that demonstrates a unique, real time imaging inventive art enabling a different kind of look at the brain, actually, to see inside neuronal and glial circuitry in the brain and spinal cord of the living human being and animal. “Lewy body dementia is characterized by the abnormal buildup of proteins into masses known as Lewy bodies. This protein is also associated with Parkinson’s disease. People who have Lewy bodies in their brains also have the plaques and tangles associated with Alzheimer's disease. Apr 26, 2019, Mayo clinic”.1 This is the problem and thus far, the problem is addressed primarily after autopsy, called post mortem, also problematic. Therefore, the purpose of this paper is to introduce the online and real time and spatial sensitive voltaic image of the Tau peptide complex video-tracked by the BRODERICK PROBE® biomedical sensors in striatum of the living Parkinson subject. This nanoprobe enables studies of the striking consequences among intensities of phosphorylated Tau. Identifying Tau on line is unmistakably relevant to longevity, both individual and societal and this relevance is inexorably critical to and on behalf of humanity per se.
这篇“简短而甜蜜”的临床论文是关于下一代“上升”的纳米技术,它展示了一种独特的、实时成像的发明艺术,可以用不同的方式观察大脑,实际上,可以看到活体人类和动物大脑和脊髓中的神经元和神经胶质回路。“路易体痴呆的特征是蛋白质异常堆积成被称为路易体的肿块。这种蛋白质也与帕金森病有关。大脑中有路易小体的人也有与阿尔茨海默病相关的斑块和缠结。2019年4月26日,梅奥诊所这就是问题所在,到目前为止,这个问题主要是在尸检后解决的,也就是所谓的验尸后。因此,本文的目的是介绍由BRODERICK PROBE®生物医学传感器在活着的帕金森受试者纹状体中跟踪的Tau肽复合物的在线实时和空间敏感的光伏图像。这种纳米探针能够研究磷酸化Tau强度之间的显著后果。在网上识别Tau无疑与个人和社会的长寿有关,这种相关性对人类本身至关重要。
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引用次数: 0
Neonatal occlusion by strangulation of the caeco-appendix in a type I omphalocele of aitken: rare case 新生儿阻塞由掐死的盲肠阑尾在I型脐膨出艾特肯:罕见的情况
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00394
Boris Mvls Gogan
The omphalocele constitutes a embryofoetopathy which exposes the newborn to multiple complications including digestive one. We report the case of a newborn with Aïtken type I omphalocele under tanning according to the Grob method having secondarily presented a neonatal occlusion. Surgical exploration found a tight neck of 4 cm with a sac containing the ascending colon and the strangulated caeco-appendix at the level of the neck. We proceed to the reduction of the handles. We also noted on exploration, an arrangement of the handles in an incomplete common mesentery. He underwent an appendectomy then a provision of the slender handles on the right and the colon on the left according to the LADD procedure with closure of the abdominal cavity in one step. The operative consequences were simple after a follow-up of 6 months.
脐膨出是一种胚胎畸形,使新生儿面临包括消化系统并发症在内的多种并发症。我们报告的情况下,新生儿与Aïtken型I型脐膨出根据Grob方法晒有继发性新生儿闭塞。手术探查发现颈部狭窄,长4厘米,颈部有一个囊,囊内包含升结肠和颈部水平处绞窄的盲肠阑尾。我们继续减少手柄。我们还注意到,在一个不完整的共同肠系膜上的把手的排列。他接受了阑尾切除术,然后在右侧提供细长的手柄,在左侧提供结肠,根据LADD程序,一步关闭腹腔。术后随访6个月,手术效果简单。
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引用次数: 1
Left ventricular outflow tract obstruction after transcatheter mitral valve replacement: the importance of preprocedural planning and prevention 经导管二尖瓣置换术后左心室流出道梗阻:术前规划及预防的重要性
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00395
M. Abdulbasit
Given the prevalence of mitral valve pathology in high-risk patients, transcatheter mitral valve replacement (TMVR) is becoming an attractive treatment modality. A known complication of TMVR is left ventricular outflow tract obstruction (LVOT) due to the prosthetic mitral valve and native anterior mitral valve leaflet encroaching into the LVOT. This is a serious complication which can lead to decreased cardiac output and death. Preprocedural planning with various imaging modalities (multi-detector cardiac CT and echocardiography) can predict those at high risk of LVOT obstruct. To increase awareness and to prevent this complication from occurring in the future, we present a case of LVOT obstruction after TMVR.
鉴于高危患者二尖瓣病变的普遍性,经导管二尖瓣置换术(TMVR)正成为一种有吸引力的治疗方式。TMVR的一个已知并发症是左心室流出道阻塞(LVOT),这是由于人工二尖瓣和天然二尖瓣前叶侵入LVOT而引起的。这是一种严重的并发症,可导致心输出量减少和死亡。术前规划各种成像方式(多探测器心脏CT和超声心动图)可以预测LVOT阻塞的高危患者。为了提高人们的认识,并防止这种并发症在未来发生,我们提出一例颞下颌颞下颌静脉手术后LVOT阻塞的病例。
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引用次数: 0
Bilateral absence of vas deferens (BAVD) a case report 双侧输精管缺失1例
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00383
M. Mohammed
Mutations in transmembrane conductance of cystic fibrosis (CFTR) are found in men in couples followed for infertility and for which azoospermia associated with congenital bilateral absence of the deferential canal (CBAVD) were found in men. There is a frequent association between CFTR and CBAVD abnormalities. CBAVD exists in almost all men with cystic fibrosis and causes an obstructive azoospermia that cannot be treated surgically; this poses a diagnostic and therapeutic problem because its management remains complex. However, with the use of assisted reproductive techniques (ART), in particular the aspiration of testicular or epididymic sperm, the injection of intracytoplasmic sperm and in vitro fertilization, it is possible that men with CBAVD can produce offspring. We report the case of a 32-year-old patient who consulted for primary infertility evolving over the past 5 years (genetic advice was provided). The aim of this article is to show the diagnostic and therapeutic difficulties related to this particular form of male primary infertility. Recent assisted human reproduction techniques like Intracytoplasmic Sperm Injection (ICSI) or In Vitro Fertilization (FIV) offer very good results for couple consulting for infertility of man with CBAVD.
囊性纤维化跨膜传导(CFTR)突变在男性不育夫妇中发现,男性无精子症伴有先天性双侧管缺失(ccbvd)。CFTR和cavd异常之间有频繁的关联。cavd存在于几乎所有患有囊性纤维化的男性中,并导致无法通过手术治疗的阻塞性无精子症;这是一个诊断和治疗问题,因为它的管理仍然很复杂。然而,通过使用辅助生殖技术(ART),特别是睾丸或附睾精子的抽吸,卵胞浆内精子的注射和体外受精,有可能使患有CBAVD的男性产生后代。我们报告的情况下,32岁的患者谁咨询原发性不孕症演变在过去的5年(遗传建议提供)。这篇文章的目的是显示诊断和治疗困难有关的这种特殊形式的男性原发性不育症。最近的辅助人类生殖技术,如卵胞浆内单精子注射(ICSI)或体外受精(FIV),为夫妇咨询患有CBAVD的男性不孕症提供了非常好的结果。
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引用次数: 0
A difficult airway made worse by apprehension: an obese young male with COVID 19 由于忧虑,气道困难变得更糟:一名患有COVID - 19的肥胖年轻男性
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00398
Ishan N Perera
Intubation of a critically ill patient in the emergency department is always considered a difficult airway. Timing, patient factors which are not optimized, and intubation done by infrequent intubators. Add to this the complications and demands of Covid 19 pandemic which make crash intubations a thing feared for personal safety as well as successful completion of intubation without complications. If the patient has intrinsic comorbid conditions contributing to a difficult airway, worse the procedure would be. Furthermore, Covid pneumonia presents its own challenges in preoxygenation, timing of the intubation, ventilation of the patient and transport as well. This is a patient I came across during the third wave of covid19 pandemic in Sri Lanka, working in the Emergency department night shift. He came in acute respiratory distress and required intubation and ventilation.
急诊科的危重病人插管一直被认为是一个困难的气道。时机,患者因素未优化,插管次数少。再加上Covid - 19大流行的并发症和需求,这使得急救插管成为一件危及人身安全的事情,以及成功完成插管而没有并发症。如果患者有导致气道困难的内在合并症,则手术会更糟糕。此外,新冠肺炎在预充氧、插管时机、患者通气和运输方面也存在挑战。这是我在斯里兰卡第三波covid - 19大流行期间遇到的一位病人,当时我在急诊科上夜班。他出现急性呼吸窘迫,需要插管和通气。
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引用次数: 0
Hyperbaric oxygen therapy caused tympanic membrane and ventricular hemorrhage: a case report 高压氧治疗致鼓膜及脑室出血1例
Pub Date : 2021-01-01 DOI: 10.15406/mojcr.2021.11.00382
Chunhui Yang
A 40-year-old male undergoing rehabilitation with hyperbaric oxygen therapy (HBOT) three months after an acute right frontal lobe cerebral infarction. On the second day of HBOT, he felt a significant blockage and pain in his left ear during and after the treatment. The endoscopic assessment of the ear and nose revealed haemorrhage in the left ear tympanic membrane and hemorrhagic effusion in the tympanic chamber. The nasal septum was found to be left deviated resulting in significant narrowing of the left nasal cavity and significant poor ventilation. Laboratory tests showed normal blood count and normal blood coagulation count. The final diagnosis of haemorrhage and fluid accumulation in the tympanic chamber of the left ear was made. After the treatment of the middle ear ball blowing once a day for 10 days, the pure tone audiometry of the left ear reached the level of the right ear, and the blockage and pain in the left ear disappeared completely. The orthoscopy inspection indicated total absorption of hemorrhagic fluid in the tympanic chamber of the left ear. This is the first report that HBOT caused tympanic membrane haemorrhage and offers new insights into the prevention of comorbidities in HBOT.
一位40岁男性在急性右额叶脑梗死后三个月接受高压氧治疗(HBOT)康复。在HBOT的第二天,他在治疗期间和治疗后感到左耳明显堵塞和疼痛。耳鼻内窥镜检查发现左耳鼓膜出血,鼓室出血积液。发现鼻中隔左偏,导致左鼻腔明显变窄,通风不良。化验显示血液计数和凝血计数正常。最后诊断为左耳鼓室出血及积液。每天吹中耳球1次,连续10天治疗后,左耳纯音听力学达到右耳水平,左耳堵塞、疼痛完全消失。镜检显示左耳鼓室出血液完全吸收。这是首次报道HBOT引起鼓膜出血,为预防HBOT的合并症提供了新的见解。
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引用次数: 0
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MOJ clinical & medical case reports
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