首页 > 最新文献

Techniques in regional anesthesia & pain management最新文献

英文 中文
Co-existence of Leclercia adecarboxylata (LSE-1) and Bradyrhizobium sp. (LSBR-3) in nodule niche for multifaceted effects and profitability in soybean production. Leclercia adecarboxylata (LSE-1) 和 Bradyrhizobium sp. (LSBR-3) 共存于大豆生产中的结核位点,产生多方面影响并带来收益。
Pub Date : 2019-10-31 DOI: 10.1007/s11274-019-2752-4
K C Kumawat, Poonam Sharma, Inderjeet Singh, Asmita Sirari, B S Gill

The present study was designed with the objective of improving growth and nodulation of soybean [Glycine max (L.) Merill] with co-inoculation of native Bradyrhizobium sp. (LSBR-3) (KF906140) and non-rhizobial nodule endophytic diazotroph Leclercia adecarboxylata (LSE-1) (KX925974) with multifunctional plant growth promoting (PGP) traits in cereal based cropping system (Rice-Wheat). A total of 40 endophytic bacteria from cultivated and wild sp. of soybean were screened for multifarious PGP traits and pathogenicity test. Based on PGP traits, antagonistic activities and bio-safety test; L. adecarboxylata (LSE-1) was identified with 16 S rRNA gene sequencing along with the presence of nifH (nitrogen fixation) and ipdc (IAA production) genes. Dual inoculant LSE-1 and LSBR-3 increased indole acetic acid (IAA), P & Zn-solubilization, 1-aminocyclopropane-1-carboxylate deaminase (ACCD) activity, siderophore, biofilm formation and exo-polysaccharides in contrast to single inoculation treatment. Further, assessment of dual inoculant LSBR-3 + LSE-1 improved growth parameters, nodulation, soil enzymes activities, nutrient accumulation and yield as compared to single as well as un-inoculated control treatment under field conditions. Single inoculant LSBR-3 improved yield by 8.84% over control. Further, enhancement of 4.15% grain yield was noticed with LSBR-3 + LSE-1 over LSBR-3 alone treatment. Application of LSBR-3 + LSE-1 gave superior B:C ratio (1.29) and additional income approximately 116 USD ha-1 in contrast to control treatment. The present results thus, is the first report of novel endophytic diazotroph L. adecarboxylata (LSE-1) as PGPR from Indian conditions particularly in Punjab region for exploiting as potential PGPR along with Bradyrhizobium sp. (LSBR-3) in soybean.

本研究的目的是在以谷物为基础的种植系统(水稻-小麦)中,通过共同接种具有多功能植物生长促进(PGP)性状的本地根瘤芽孢杆菌(LSBR-3)(KF906140)和非根瘤内生重氮营养体Leclercia adecarboxylata(LSE-1)(KX925974),改善大豆[Glycine max (L.) Merill]的生长和结瘤。研究人员从大豆的栽培种和野生种中筛选出 40 种内生细菌,对其进行了多种 PGP 性状和致病性测试。根据 PGP 性状、拮抗活性和生物安全性测试,用 16 S rRNA 基因测序鉴定出 L. adecarboxylata(LSE-1),并发现其含有 nifH(固氮)和 ipdc(产生 IAA)基因。与单一接种处理相比,LSE-1 和 LSBR-3 双接种剂增加了吲哚乙酸(IAA)、磷和锌溶解度、1-氨基环丙烷-1-羧酸脱氨酶(ACCD)活性、苷元、生物膜形成和外多糖。此外,在田间条件下,与单一接种和未接种的对照处理相比,双重接种剂 LSBR-3 + LSE-1 的评估改善了生长参数、结节、土壤酶活性、养分积累和产量。单一接种剂 LSBR-3 比对照增产 8.84%。此外,LSBR-3 + LSE-1 的谷物产量比单独使用 LSBR-3 的处理提高了 4.15%。与对照处理相比,施用 LSBR-3 + LSE-1 可提高 B:C 比率(1.29),增加收入约 116 美元/公顷。因此,本研究结果是印度(尤其是旁遮普地区)首次报道新型内生重氮营养体 L. adecarboxylata(LSE-1)作为 PGPR 与 Bradyrhizobium sp.(LSBR-3)一起用于大豆。
{"title":"Co-existence of Leclercia adecarboxylata (LSE-1) and Bradyrhizobium sp. (LSBR-3) in nodule niche for multifaceted effects and profitability in soybean production.","authors":"K C Kumawat, Poonam Sharma, Inderjeet Singh, Asmita Sirari, B S Gill","doi":"10.1007/s11274-019-2752-4","DOIUrl":"10.1007/s11274-019-2752-4","url":null,"abstract":"<p><p>The present study was designed with the objective of improving growth and nodulation of soybean [Glycine max (L.) Merill] with co-inoculation of native Bradyrhizobium sp. (LSBR-3) (KF906140) and non-rhizobial nodule endophytic diazotroph Leclercia adecarboxylata (LSE-1) (KX925974) with multifunctional plant growth promoting (PGP) traits in cereal based cropping system (Rice-Wheat). A total of 40 endophytic bacteria from cultivated and wild sp. of soybean were screened for multifarious PGP traits and pathogenicity test. Based on PGP traits, antagonistic activities and bio-safety test; L. adecarboxylata (LSE-1) was identified with 16 S rRNA gene sequencing along with the presence of nifH (nitrogen fixation) and ipdc (IAA production) genes. Dual inoculant LSE-1 and LSBR-3 increased indole acetic acid (IAA), P & Zn-solubilization, 1-aminocyclopropane-1-carboxylate deaminase (ACCD) activity, siderophore, biofilm formation and exo-polysaccharides in contrast to single inoculation treatment. Further, assessment of dual inoculant LSBR-3 + LSE-1 improved growth parameters, nodulation, soil enzymes activities, nutrient accumulation and yield as compared to single as well as un-inoculated control treatment under field conditions. Single inoculant LSBR-3 improved yield by 8.84% over control. Further, enhancement of 4.15% grain yield was noticed with LSBR-3 + LSE-1 over LSBR-3 alone treatment. Application of LSBR-3 + LSE-1 gave superior B:C ratio (1.29) and additional income approximately 116 USD ha<sup>-1</sup> in contrast to control treatment. The present results thus, is the first report of novel endophytic diazotroph L. adecarboxylata (LSE-1) as PGPR from Indian conditions particularly in Punjab region for exploiting as potential PGPR along with Bradyrhizobium sp. (LSBR-3) in soybean.</p>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"1 1","pages":"172"},"PeriodicalIF":0.0,"publicationDate":"2019-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11274-019-2752-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78394604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
A prospective evaluation of the availability and utility of the Ambulance Call Record in the emergency department - ERRATUM. 对急诊科救护车呼叫记录的可用性和实用性的前瞻性评估 - ERRATUM。
IF 2.4 Pub Date : 2017-01-01 Epub Date: 2016-09-29 DOI: 10.1017/cem.2016.399
Natalie Cram, Shelley McLeod, Michael Lewell, Matthew Davis
{"title":"A prospective evaluation of the availability and utility of the Ambulance Call Record in the emergency department - ERRATUM.","authors":"Natalie Cram, Shelley McLeod, Michael Lewell, Matthew Davis","doi":"10.1017/cem.2016.399","DOIUrl":"10.1017/cem.2016.399","url":null,"abstract":"","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"5 1","pages":"79"},"PeriodicalIF":2.4,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80430202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracic radiofrequency ablation 胸部射频消融术
Pub Date : 2015-07-01 DOI: 10.1053/j.trap.2016.10.004
Mehul J. Desai MD, MPH

Thoracic spine pain is a relatively common condition. Pain in this region may be attributable to dysfunction of the thoracic facet joint. The true prevalence of thoracic facet pain remains somewhat elusive. Although challenging to diagnose at times, this joint is amenable to several therapeutic options. Radiofrequency neurotomy and thoracic medial branch blocks are normally used to treat facetogenic pain originating in the thoracic spine. Although demonstrating promise, larger, robustly designed trials are needed to further elucidate the appropriate treatment of this disorder.

胸椎疼痛是一种比较常见的疾病。这一区域的疼痛可能是由于胸椎小关节功能障碍引起的。胸椎关节突疼痛的真实患病率仍然有些难以捉摸。虽然有时诊断具有挑战性,但这种关节可以接受几种治疗选择。射频神经切开术和胸椎内侧分支阻滞术通常用于治疗起源于胸椎的面源性疼痛。虽然显示出希望,但需要更大规模、设计可靠的试验来进一步阐明这种疾病的适当治疗。
{"title":"Thoracic radiofrequency ablation","authors":"Mehul J. Desai MD, MPH","doi":"10.1053/j.trap.2016.10.004","DOIUrl":"10.1053/j.trap.2016.10.004","url":null,"abstract":"<div><p><span><span>Thoracic spine pain is a relatively common condition. Pain in this region may be attributable to dysfunction of the thoracic </span>facet joint. The true prevalence of thoracic facet pain remains somewhat elusive. Although challenging to diagnose at times, this joint is amenable to several therapeutic options. Radiofrequency </span>neurotomy<span> and thoracic medial branch blocks are normally used to treat facetogenic pain originating in the thoracic spine. Although demonstrating promise, larger, robustly designed trials are needed to further elucidate the appropriate treatment of this disorder.</span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"19 3","pages":"Pages 126-130"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2016.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58061374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
FMi: Editorial Board FMi:编委会
Pub Date : 2015-07-01 DOI: 10.1053/S1084-208X(16)30044-1
{"title":"FMi: Editorial Board","authors":"","doi":"10.1053/S1084-208X(16)30044-1","DOIUrl":"10.1053/S1084-208X(16)30044-1","url":null,"abstract":"","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"19 3","pages":"Page A1"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/S1084-208X(16)30044-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58312756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiofrequency strategies to target peripheral large joint orthopedic pain 针对周围大关节矫形疼痛的射频策略
Pub Date : 2015-07-01 DOI: 10.1053/j.trap.2016.10.005
Jeffrey D. Petersohn MD

Partial neurotomy of painful large joints may be accomplished by radiofrequency (RF) lesioning of the articular branch innervation of these joints. Successful RF lesions of the knee and the hip are clinically useful procedures whose success depends upon the knowledge of articular branch neuro anatomy and the practitioner’s optimized choice of RF probe for the procedure. Although clearly indicated for patients who may not be medically suitable for arthroplasty, the procedures may be invaluable in preserving functional mobility and providing non-opiate pain relief for many patients with articular pain including those with postarthroplasty pain. Techniques for diagnostic nerve blocks and varied approaches for anatomically optimized RF lesioning of the innervation of the hip and knee are provided.

疼痛大关节的部分神经切断术可以通过射频(RF)损伤这些关节的关节分支神经支配来完成。成功的射频损伤膝关节和髋关节是临床有用的手术,其成功取决于关节分支神经解剖学知识和医生对射频探头的最佳选择。虽然明确指出,对于医学上不适合进行关节置换术的患者,该手术在保留功能活动能力和为许多关节疼痛患者(包括关节置换术后疼痛患者)提供非阿片类疼痛缓解方面可能是非常宝贵的。提供了诊断神经阻滞的技术和各种解剖优化的髋关节和膝关节神经支配射频损伤的方法。
{"title":"Radiofrequency strategies to target peripheral large joint orthopedic pain","authors":"Jeffrey D. Petersohn MD","doi":"10.1053/j.trap.2016.10.005","DOIUrl":"10.1053/j.trap.2016.10.005","url":null,"abstract":"<div><p><span>Partial neurotomy<span> of painful large joints may be accomplished by radiofrequency (RF) lesioning of the articular branch innervation of these joints. Successful RF lesions of the knee and the hip are clinically useful procedures whose success depends upon the knowledge of articular branch </span></span>neuro anatomy<span> and the practitioner’s optimized choice of RF probe for the procedure. Although clearly indicated for patients who may not be medically suitable for arthroplasty, the procedures may be invaluable in preserving functional mobility and providing non-opiate pain relief for many patients with articular pain including those with postarthroplasty pain. Techniques for diagnostic nerve blocks and varied approaches for anatomically optimized RF lesioning of the innervation of the hip and knee are provided.</span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"19 3","pages":"Pages 131-137"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2016.10.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58060957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Radiofrequency ablation of splanchnic nerves for control of chronic abdominal pain 射频消融术治疗慢性腹痛
Pub Date : 2015-07-01 DOI: 10.1053/j.trap.2016.10.007
Leonardo Kapural MD, PhD

Chronic abdominal pain is a complex physical and psychological problem that requires comprehensive treatment options tailored to the needs of patients. Splanchnic nerve blocks and radiofrequency denervation of greater and lesser splanchnic nerves may provide prolonged treatment effect that still needs to be studied in a randomized prospective fashion. Here we describe improved fluoroscopy-guided technique for the radiofrequency ablation of splanchnic nerves, details on approach, technique, and potential complications.

慢性腹痛是一种复杂的生理和心理问题,需要根据患者的需要进行综合治疗。内脏神经阻滞和大、小内脏神经的射频去神经支配可能提供长期的治疗效果,但仍需要随机前瞻性的研究。在这里,我们描述改进的透视引导下射频消融内脏神经的技术,详细的入路,技术和潜在的并发症。
{"title":"Radiofrequency ablation of splanchnic nerves for control of chronic abdominal pain","authors":"Leonardo Kapural MD, PhD","doi":"10.1053/j.trap.2016.10.007","DOIUrl":"10.1053/j.trap.2016.10.007","url":null,"abstract":"<div><p><span><span>Chronic abdominal pain is a complex physical and psychological problem that requires comprehensive treatment options tailored to the needs of patients. </span>Splanchnic nerve<span> blocks and radiofrequency denervation of greater and lesser splanchnic nerves may provide prolonged treatment effect that still needs to be studied in a randomized prospective fashion. Here we describe improved fluoroscopy-guided technique for the </span></span>radiofrequency ablation of splanchnic nerves, details on approach, technique, and potential complications.</p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"19 3","pages":"Pages 138-142"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2016.10.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58060979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Technical aspects of conventional and water-cooled monopolar lumbar radiofrequency rhizotomy 常规和水冷单极腰椎射频根切断术的技术方面
Pub Date : 2015-07-01 DOI: 10.1053/j.trap.2016.10.001
Richard D. Ball MD, PhD

Radiofrequency ablation (RFA) is a safe and effective pain therapy with efficacy principally reliant upon induced thermal damage of neural sensory afferents. Most peripheral RFA involves induced axonal damage but cell bodies may be involved indirectly. Radiofrequency electrodes (RFE) are not simple high-temperature probes and better insight regarding RFE function from an electrical engineering viewpoint may improve clinical outcomes by reducing the risk of poor or inadequate heating of the target nerves. RFE heating is highly influenced by the configuration and properties of the perielectrode tissues with the shape and size of RFE-produced protein coagulum seen in vitro with homogeneous media such as egg white, liver, or chicken skeletal muscle undoubtedly significantly different than the biological lesions occurring during in vivo clinical use. Understanding RFA requires consideration of the nature of the specific perielectrode tissues. A theoretical basis for optimized RFE function for lumbar medial branch (MB) neurotomy is presented with introduction of the concepts of clinically useful heating and useless heating. Conventional RFE is limited in the amount of current/heating produced for a given active electrode surface area before producing a radiofrequency generator fault and an inverse relationship exists between clinically useful heating and useless heating. Technical details of RFE function are discussed that may differ from presently accepted technique. Tined RFE, similar in function to conventional RFE, may offer a small advantage if properly used, and possibly a disadvantage if used incorrectly. Directly conducted heat is often neglected in considering RFA, but should be considered, especially with water-cooled RFE (WCRFE). Theory and empirical results suggest that WCRFE might become a preferred tool for much, but not all, RFA, but adoption has been limited by electrode cost and reimbursement policies. Conventional and tined RFE may produce poor outcomes if placed improperly, but complications due to overheating are quite rare. Conversely, WCRFE introduces far more heat into perielectrode tissues and reduces the likelihood of a poor clinical outcome, but avoidance of complications due to overheating of adjacent tissues requires a thoughtful understanding of the spatial and thermal characteristics of the WCRFE.

射频消融(RFA)是一种安全有效的疼痛治疗方法,其疗效主要依赖于对神经感觉传入神经的热损伤。大多数外周RFA涉及诱导轴突损伤,但可能间接涉及细胞体。射频电极(RFE)不是简单的高温探头,从电气工程的角度更好地了解RFE功能可以通过减少目标神经加热不良或不充分的风险来改善临床结果。RFE加热受电极周围组织的结构和性质的高度影响,在体外用均匀介质(如蛋清、肝脏或鸡骨骼肌)观察到的RFE产生的蛋白凝固物的形状和大小无疑与体内临床使用中发生的生物病变有显著不同。理解RFA需要考虑特定电极周围组织的性质。介绍了临床有用加热和无用加热的概念,为优化腰椎内侧支神经切开术RFE功能提供了理论基础。传统的RFE在产生射频发生器故障之前,对给定的活性电极表面积产生的电流/加热量是有限的,并且在临床上有用的加热和无用的加热之间存在反比关系。讨论了RFE功能的技术细节,可能与目前接受的技术不同。定时RFE在功能上与传统RFE类似,如果使用得当,可能会有一点优势,如果使用不当,可能会有缺点。在考虑RFE时,直接传导的热量往往被忽略,但应该考虑,特别是水冷RFE (WCRFE)。理论和实证结果表明,WCRFE可能成为许多RFA的首选工具,但不是所有RFA的首选工具,但其采用受到电极成本和报销政策的限制。如果放置不当,常规和定时RFE可能会产生不良结果,但由于过热引起的并发症相当罕见。相反,WCRFE将更多的热量引入电极周围组织,降低了不良临床结果的可能性,但为了避免因邻近组织过热而引起的并发症,需要对WCRFE的空间和热特性有深入的了解。
{"title":"Technical aspects of conventional and water-cooled monopolar lumbar radiofrequency rhizotomy","authors":"Richard D. Ball MD, PhD","doi":"10.1053/j.trap.2016.10.001","DOIUrl":"10.1053/j.trap.2016.10.001","url":null,"abstract":"<div><p>Radiofrequency ablation<span><span> (RFA) is a safe and effective pain therapy with efficacy principally reliant upon induced thermal damage of neural sensory afferents. Most peripheral RFA involves induced axonal damage but cell bodies may be involved indirectly. Radiofrequency electrodes (RFE) are not simple high-temperature probes and better insight regarding RFE function from an electrical engineering viewpoint may improve clinical outcomes by reducing the risk of poor or inadequate heating of the target nerves. RFE heating is highly influenced by the configuration and properties of the perielectrode tissues with the shape and size of RFE-produced protein coagulum seen in vitro with homogeneous media such as egg white, liver, or chicken </span>skeletal muscle<span> undoubtedly significantly different than the biological lesions occurring during in vivo clinical use. Understanding RFA requires consideration of the nature of the specific perielectrode tissues. A theoretical basis for optimized RFE function for lumbar medial branch (MB) neurotomy is presented with introduction of the concepts of clinically useful heating and useless heating. Conventional RFE is limited in the amount of current/heating produced for a given active electrode surface area before producing a radiofrequency generator fault and an inverse relationship exists between clinically useful heating and useless heating. Technical details of RFE function are discussed that may differ from presently accepted technique. Tined RFE, similar in function to conventional RFE, may offer a small advantage if properly used, and possibly a disadvantage if used incorrectly. Directly conducted heat is often neglected in considering RFA, but should be considered, especially with water-cooled RFE (WCRFE). Theory and empirical results suggest that WCRFE might become a preferred tool for much, but not all, RFA, but adoption has been limited by electrode cost and reimbursement policies. Conventional and tined RFE may produce poor outcomes if placed improperly, but complications due to overheating are quite rare. Conversely, WCRFE introduces far more heat into perielectrode tissues and reduces the likelihood of a poor clinical outcome, but avoidance of complications due to overheating of adjacent tissues requires a thoughtful understanding of the spatial and thermal characteristics of the WCRFE.</span></span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"19 3","pages":"Pages 96-108"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2016.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58061249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cervical spine pain related to the facet joints 颈椎疼痛与小关节有关
Pub Date : 2015-07-01 DOI: 10.1053/j.trap.2016.10.002
Kenneth D. Candido MD, Bryant England MD

Neck pain is a common diagnostic entity, with a lifetime prevalence of between 65% and 80%. Appreciation of the role of the cervical facet joints in the etiology of cervical spine pain is paramount to providing sustained pain relief for individuals suffering from degenerative and posttraumatic neck pain. Studies have demonstrated that approximately 60% of patients who sustain whiplash-type rear-end motor vehicle collisions would have pain that results from the facet joints alone, or in conjunction with the cervical intervertebral disks. An appreciation of the anatomical foundation for the development of these painful conditions includes knowledge of the dual, overlapping innervation of each cervical facet joint with contributions from levels at, and above the joint. Medial branch nerves invest the joints; are held closely adherent to the articular pillars by tendons of the semispinalis capitis muscles; and can be treated using local anesthetic nerve blocks followed by radiofrequency (RF) procedures for prolonged benefit. Nerves in facet joints contain modified nociceptors, including silent nociceptors, low-threshold mechanoreceptors, and mechanically sensitive nociceptors. Nerves within facet joints are both free and encapsulated and contain Substance P and calcitonin gene–related peptide. Treatment approaches must address these diverse anatomical and physiological phenomena to provide the highest level of interventional therapy. Large, well-conducted studies have demonstrated the efficacy and safety of providing short-term symptomatic pain relief using cervical facet medial branch nerve blocks. Continuous-energy thermal lesioning RF ablation techniques of the cervical medial branches may produce pain relief that persists for up to 12 months in two-thirds of patients so treated. A systematic review of well-conducted studies recently published confirmed that the evidence in favor of using RF ablation is level II for the long-term effectiveness of RF neurotomy and facet joint nerve blocks in managing cervical facet joint pain. Imaging for performing these procedures is mandatory to assure success and to minimize adverse events from occurring. Fluoroscopy is a standard imaging technique, but ultrasound and even computed tomography scan guidance have been documented to be satisfactory in properly trained interventionalists. The cervical facet joints with their medial branches represent a reliable target for directing interventional therapies aimed at addressing nociceptive type pain, albeit with a neurogenic component. Future studies would reflect our evolving appreciation of these intricate anatomical networks of innervation and their role in the etiology of chronic headache and neck pain.

颈部疼痛是一种常见的诊断症状,其终生患病率在65%至80%之间。了解颈椎小关节在颈椎疼痛病因学中的作用,对于为患有退行性和创伤后颈部疼痛的个体提供持续的疼痛缓解至关重要。研究表明,大约60%遭受鞭打型追尾机动车碰撞的患者会有单独由小关节引起的疼痛,或与颈椎间盘联合引起的疼痛。了解这些疼痛状况发展的解剖学基础包括了解每个颈椎小关节的双重重叠神经支配,这些神经支配来自关节处和关节上方的水平。内侧支神经支配关节;通过头半棘肌的肌腱紧紧地附着在关节柱上;并且可以使用局部麻醉神经阻滞,然后使用射频(RF)程序进行治疗,以获得长期的益处。小关节内的神经含有改良的伤害感受器,包括沉默的伤害感受器、低阈值的机械感受器和机械敏感的伤害感受器。关节突关节内的神经是游离和包被的,含有P物质和降钙素基因相关肽。治疗方法必须解决这些不同的解剖和生理现象,以提供最高水平的介入治疗。大型、良好的研究已经证明了使用颈小关节内侧支神经阻滞短期缓解症状性疼痛的有效性和安全性。颈椎内侧支射频消融技术可使三分之二的患者持续疼痛缓解长达12个月。最近发表的一项系统综述证实,在射频神经切开术和小关节神经阻滞治疗颈椎小关节疼痛的长期有效性方面,支持使用射频消融的证据为II级。为确保手术成功并减少不良事件的发生,影像学检查是强制性的。透视是一种标准的成像技术,但超声和甚至计算机断层扫描指导已被证明是令人满意的训练有素的介入医师。颈椎小关节及其内侧分支是指导介入治疗的可靠靶点,旨在解决伤害性疼痛,尽管有神经源性成分。未来的研究将反映我们对这些复杂的神经支配解剖网络及其在慢性头痛和颈部疼痛病因学中的作用的不断发展的认识。
{"title":"Cervical spine pain related to the facet joints","authors":"Kenneth D. Candido MD,&nbsp;Bryant England MD","doi":"10.1053/j.trap.2016.10.002","DOIUrl":"10.1053/j.trap.2016.10.002","url":null,"abstract":"<div><p><span>Neck pain is a common diagnostic entity, with a lifetime prevalence of between 65% and 80%. Appreciation of the role of the cervical facet joints<span><span><span> in the etiology of cervical spine pain is paramount to providing sustained pain relief for individuals suffering from degenerative and posttraumatic neck pain. Studies have demonstrated that approximately 60% of patients who sustain whiplash-type rear-end motor vehicle collisions would have pain that results from the facet joints alone, or in conjunction with the cervical </span>intervertebral disks<span><span>. An appreciation of the anatomical foundation for the development of these painful conditions includes knowledge of the dual, overlapping innervation of each cervical facet joint with contributions from levels at, and above the joint. Medial branch nerves invest the joints; are held closely adherent to the articular pillars by tendons of the semispinalis capitis muscles; and can be treated using </span>local anesthetic nerve blocks followed by radiofrequency (RF) procedures for prolonged benefit. Nerves in facet joints contain modified </span></span>nociceptors, including silent nociceptors, low-threshold </span></span>mechanoreceptors<span><span><span><span>, and mechanically sensitive nociceptors. Nerves within facet joints are both free and encapsulated and contain Substance P and calcitonin gene–related peptide. Treatment approaches must address these diverse anatomical and physiological phenomena to provide the highest level of </span>interventional therapy. Large, well-conducted studies have demonstrated the efficacy and safety of providing short-term symptomatic pain relief using cervical facet medial branch nerve blocks. Continuous-energy thermal lesioning RF </span>ablation techniques of the cervical medial branches may produce pain relief that persists for up to 12 months in two-thirds of patients so treated. A </span>systematic review<span><span> of well-conducted studies recently published confirmed that the evidence in favor of using RF ablation<span><span> is level II for the long-term effectiveness of RF neurotomy and facet joint nerve blocks in managing cervical facet joint pain. Imaging for performing these procedures is mandatory to assure success and to minimize adverse events from occurring. </span>Fluoroscopy<span> is a standard imaging technique, but ultrasound and even </span></span></span>computed tomography scan guidance have been documented to be satisfactory in properly trained interventionalists. The cervical facet joints with their medial branches represent a reliable target for directing interventional therapies aimed at addressing nociceptive type pain, albeit with a neurogenic component. Future studies would reflect our evolving appreciation of these intricate anatomical networks of innervation and their role in the etiology of chronic headache and neck pain.</span></span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"19 3","pages":"Pages 109-118"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2016.10.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58061291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
FMii: Table of Contents FMii:目录
Pub Date : 2015-07-01 DOI: 10.1053/S1084-208X(16)30046-5
{"title":"FMii: Table of Contents","authors":"","doi":"10.1053/S1084-208X(16)30046-5","DOIUrl":"https://doi.org/10.1053/S1084-208X(16)30046-5","url":null,"abstract":"","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"19 3","pages":"Page A2"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/S1084-208X(16)30046-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138427690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiofrequency ablation of the sacral lateral branches 骶骨外侧分支的射频消融
Pub Date : 2015-07-01 DOI: 10.1053/j.trap.2016.10.003
Bruce Vrooman MD, MS, FIPP, Victor Foorsov MD

The objective of this article is to recommend an approach to radiofrequency ablation (RFA) of the sacral lateral branches that is safe, effective, and simple to perform. To do so, one must identify the proper patient, perform a diagnostic block to confirm the sacroiliac joint as the pain generator, and then, after 2 successful blocks, move to RFA of the sacral lateral branches as the next step in treatment. The choice of an RFA technique is controversial. Here, an argument is made for moving to bipolar RFA of the lateral branches of S1-S3. If pain is refractory, then cooled RFA may be an appropriate next step in care.

本文的目的是推荐一种安全、有效且操作简单的骶骨外侧分支射频消融(RFA)方法。要做到这一点,必须确定合适的病人,进行诊断阻断以确认骶髂关节是疼痛的产生者,然后,在两次成功的阻断后,将骶骨外侧分支的射频消融作为下一步治疗。RFA技术的选择是有争议的。在这里,我们提出了一个论点,即移动到双极RFA的S1-S3侧分支。如果疼痛是难治性的,那么冷却RFA可能是适当的下一步护理。
{"title":"Radiofrequency ablation of the sacral lateral branches","authors":"Bruce Vrooman MD, MS, FIPP,&nbsp;Victor Foorsov MD","doi":"10.1053/j.trap.2016.10.003","DOIUrl":"10.1053/j.trap.2016.10.003","url":null,"abstract":"<div><p>The objective of this article is to recommend an approach to radiofrequency ablation<span><span> (RFA) of the sacral lateral branches that is safe, effective, and simple to perform. To do so, one must identify the proper patient, perform a diagnostic block to confirm the sacroiliac joint as the pain generator, and then, after 2 successful blocks, move to RFA of the sacral lateral branches as the next step in </span>treatment. The choice of an RFA technique is controversial. Here, an argument is made for moving to bipolar RFA of the lateral branches of S1-S3. If pain is refractory, then cooled RFA may be an appropriate next step in care.</span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"19 3","pages":"Pages 119-125"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2016.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58061344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Techniques in regional anesthesia & pain management
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1