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The effect of the size of pedicle screw on the long-term radiological and clinical results of short-segment posterior instrumentation in the management of thoracolumbar vertebral fractures. 椎弓根螺钉的大小对短节段后路器械治疗胸腰椎骨折的长期放射学和临床效果的影响。
Pub Date : 2024-01-01 DOI: 10.5152/j.aott.2024.23056
Anıl Murat Öztürk, Onur Süer, Selahaddin Aydemir, Bünyamin Kılıçlı, Ömer Akçalı

Objective: It was aimed at evaluating the effect of the size of the pedicle screw placed on the fractured vertebra on the long-term radiological and clinical results of short-segment posterior instrumentation applied in the surgical treatment of thoracolumbar vertebral fractures.

Methods: This retrospective study included 36 patients who underwent short-segment posterior instrumentation surgery for a single-level thoracolumbar (T11-L2) fracture between January 2015 and March 2021. The patients included in the study were divided into 2 groups according to the size of the pedicle screw placed in the fractured vertebra (group A: intermediate screw 4.5 mm, ≤35 mm+less than 50% of the vertebral corpus length, m/f: 13/4, n: 17, age: 36.5; group B: intermediate screw 5.5 mm, ≥40 mm+more than 70% of the vertebral corpus length, m/f: 11/8, n: 19, age: 42.6). All patients were periodically evaluated clinically and radiologically. Vertebral compression angle (VCA), anterior and posterior vertebral body height (ABH-PBH), intraoperative parameters (instrumentation time and intraoperative fluoroscopy number), and complications were compared between the 2 groups.

Results: Both groups were comparable with respect to age, sex, level of injury, AO classification, mechanism of injury, and American Spinal Cord Injury Association impairment scale. Restoration of VCA and vertebral corpus heights was achieved sufficiently in both groups after operation (P < .0001). There was no significant difference between the 2 groups in terms of early postoperative VCA, VCA measured at final follow-up, or loss of correction in VCA. At the last follow-up, PBH was statistically significantly better preserved in group B (P=.0424). There was no difference between the 2 groups in terms of operation time and the number of intraoperative fluoroscopies. Implant failure was observed in 1 patient in group A.

Conclusion: This study has revealed that using a long, thick pedicle screw placed in the fractured vertebra can better preserve the PBH at the final follow-up. No correlation was found between the size of the intermediate screw and the preservation of the correction in the postoperative vertebral heights and VCA during the follow-up.

Level of evidence: Level III, Therapeutic Study.

目的旨在评估椎体骨折椎弓根螺钉的大小对胸腰椎骨折手术治疗中应用短节段后路器械的长期放射学和临床效果的影响:该回顾性研究纳入了2015年1月至2021年3月期间因单层胸腰椎(T11-L2)骨折而接受短节段后路器械手术治疗的36例患者。根据放置在骨折椎体内的椎弓根螺钉的大小,将纳入研究的患者分为两组(A组:中间螺钉4.5毫米,≤35毫米+小于椎体长度的50%,男/女:13/4,n:17,年龄:36.5;B 组:中间螺钉 5.5 mm,≥40 mm+ 超过椎体长度的 70%,男/女:11/8,n:19,年龄:42.6)。所有患者均定期接受临床和放射学评估。比较两组患者的椎体压缩角(VCA)、椎体前后高度(ABH-PBH)、术中参数(器械植入时间和术中透视次数)和并发症:结果:两组在年龄、性别、损伤程度、AO分类、损伤机制和美国脊髓损伤协会损伤量表方面具有可比性。两组术后均能充分恢复 VCA 和椎体高度(P < .0001)。两组患者术后早期的椎体高度、最后随访时测量的椎体高度以及椎体高度的矫正损失均无明显差异。在最后一次随访中,B 组的 PBH 保存情况明显更好(P=.0424)。两组在手术时间和术中透视次数上没有差异。A组有1名患者种植失败:本研究显示,使用粗长的椎弓根螺钉置入骨折椎体,在最终随访时能更好地保留 PBH。在随访期间,没有发现中间螺钉的大小与术后椎体高度和 VCA 矫正的保留之间存在相关性:证据等级:三级,治疗性研究。
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引用次数: 0
Intraoperative lateral wall breach simulation in the cadaveric spine and the impact of thread designs of screws on pullout strength in the osteoporotic thoracic vertebrae: A biomechanical study in human cadavers. 尸体脊柱术中侧壁破损模拟以及螺钉螺纹设计对骨质疏松胸椎拔出强度的影响:人体尸体生物力学研究。
Pub Date : 2024-01-01 DOI: 10.5152/j.aott.2024.22067
Ozcan Kaya, Okan Ozkunt, Mustafa Sungur, Mehmet Semih Cakir, Murat Baydogan, Kerim Sariyilmaz

Objective: This study aimed (1) to simulate pedicle screw pullout after intraoperative external wall perforation and (2) to assess restoration strength with different thread designs in the pedicle screw instrumentation for osteoporotic thoracic vertebrae.

Methods: Twenty fresh-frozen human cadaveric thoracic vertebra bodies were prepared and divided into 4 groups: group 1, 5.5 mm × 45 mm polyaxial single thread pedicle screws (PASTS); group 2, after wall injury 5.5 mm × 45 mm PASTS; group 3, 6.5 mm × 45 mm PASTS after wall injury; and group 4: 6.5 mm × 45 mm polyaxial mixed-threaded screws after wall injury. While group 1 was the control group, groups 2, 3, and 4 were used as study groups after the lateral wall breach. All prepared screw units were placed on a universal pullout measurement testing device.

Results: The mean bone mineral density for 20 thoracic vertebrae was 0.57 ± 0.12 g/cm2 (range 0.53-0.6 g/cm2 ). The mean pullout strength was 474.90 Newtons (N) for group 1, 412.85 N for group 2, 475.4 N for group 3, and 630.74N for group 4. The lateral wall breach caused a 14.1 % decrease in average pullout strength compared with the initial screw pullout. Mixed (double)-threaded screws increased pullout strength compared to 6.5 mm screws (P=.036) Conclusion: Using a 1 mm thicker polyaxial pedicle screw or mixed (double)-threaded pedicle screw seems to increase pullout strength; however, this was statistically significant only for group 4. In the thoracic spine, the redirection possibility of the pedicle screw is limited, and augmentation with cement will not be appropriate due to the risk of wall injury-related leakage. Therefore, care should be taken to avoid violating the lateral cortex by using appropriate pedicle entry points and trajectories.

研究目的本研究旨在(1)模拟术中外壁穿孔后椎弓根螺钉的拔出;(2)评估骨质疏松胸椎椎弓根螺钉器械中不同螺纹设计的修复强度:制备 20 个新鲜冷冻的人体胸椎椎体并将其分为 4 组:第 1 组,5.5 mm × 45 mm 多轴单螺纹椎弓根螺钉(PASTS);第 2 组,椎壁损伤后 5.5 mm × 45 mm PASTS;第 3 组,椎壁损伤后 6.5 mm × 45 mm PASTS;第 4 组,椎壁损伤后 6.5 mm × 45 mm 多轴混合螺纹螺钉。第 1 组为对照组,第 2、3 和 4 组为侧壁破损后的研究组。所有准备好的螺钉单元都被放置在通用拉力测量测试装置上:20 个胸椎的平均骨质密度为 0.57 ± 0.12 g/cm2(范围为 0.53-0.6 g/cm2)。第 1 组的平均拔出强度为 474.90 牛顿(N),第 2 组为 412.85 牛顿,第 3 组为 475.4 牛顿,第 4 组为 630.74 牛顿。与初始螺钉拔出相比,侧壁破损导致平均拔出强度下降 14.1%。与 6.5 毫米螺钉相比,混合(双)螺纹螺钉增加了拉拔强度(P=.036) 结论:使用1毫米粗的多轴椎弓根螺钉或混合(双)螺纹椎弓根螺钉似乎能增加拔出强度;但只有第4组的拔出强度具有统计学意义。在胸椎,椎弓根螺钉重新定向的可能性有限,而且由于与壁损伤相关的渗漏风险,不适合使用骨水泥增强。因此,应注意通过使用适当的椎弓根进入点和轨迹来避免侵犯侧皮质。
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引用次数: 0
Beware of Artificial Intelligence hallucinations or should we call confabulation? 警惕人工智能幻觉,或者我们应该称之为迷惑?
Pub Date : 2024-01-01 DOI: 10.5152/j.aott.2024.130224
Haluk Berk
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引用次数: 0
Management preferences of orthopedic surgeons in developmental dysplasia of the hip under 1 year of age in Türkiye: Results of a nationwide cross-sectional survey. 土耳其骨科医生对 1 岁以下髋关节发育不良患者的管理偏好:全国横断面调查结果。
Pub Date : 2023-12-22 DOI: 10.5152/j.aott.2023.23080
Baki Volkan Çetin, Sancar Bakırcıoğlu, Sadettin Çiftci, Mehmet Salih Söylemez, Serkan Erkuş, Yalçın Turhan, İsmail Yalkın Çamurcu, Serda Duman, Timur Yıldırım, Kaya Memişoğlu, Hakan Şenaran, Hakan Ömeroğlu

Objective: This study aimed to evaluate the diagnosis and treatment preferences of orthopedic surgeons in developmental dysplasia of the hip (DDH) cases under the age of 1 in Türkiye with a higher incidence of DDH, estimated to be around 5-15 per 1000 live births.

Methods: This was a nationwide cross-sectional survey. A link for the online survey, including 16 multiple-choice questions, was sent to the email group of the National Orthopedic Society.

Results: Among 233 filled-out surveys, 211 met the inclusion criteria. Half of the participants had experience of <10 years as orthopedic surgeons, managed <25% of pediatric patients in daily practice, and treated <25 DDH cases per year before walking age. Ninety-seven percent used more than one method, hip ultrasound the most common, for exact diagnosis of DDH under 6 months. Pavlik harness was the most commonly preferred brace, but the use of Tübingen orthosis increased among experienced surgeons. The uppermost age limit for bracing was higher in surgeons dealing with more pediatric patients and treating more DDH cases. Dislocated hips and hips requiring closed/open reduction were more commonly referred to other surgeons by less experienced surgeons in terms of years, number of pediatric patients, and treated DDH cases per year. The lowest age limit for intervention under general anesthesia was lower in surgeons treating >25 DDH cases per year. Over one-third used both anterior and medial approach open reduction, but a trend to anterior open reduction alone was more evident in surgeons treating >50 DDH cases per year. More experienced surgeons were more prone to check the intraoperative reduction with postoperative computed tomography or magnetic resonance imaging. Diagnosis and treatment ages of DDH cases did not significantly change during the coronavirus disease 2019 pandemic.

Conclusion: Management preferences of orthopedic surgeons in DDH before walking age primarily depend on the rate of pediatric patients in daily practice and the number of treated DDH cases per year.

研究目的土耳其的髋关节发育不良(DDH)发病率较高,估计每 1000 例活产中约有 5-15 例,本研究旨在评估骨科医生对 1 岁以下髋关节发育不良病例的诊断和治疗偏好:这是一项全国范围的横断面调查。方法:这是一项全国性的横断面调查,向全国骨科协会的电子邮件群组发送了在线调查链接,其中包括 16 道选择题:在填写的 233 份调查问卷中,有 211 份符合纳入标准。半数参与者每年有 25 例 DDH 病例。超过三分之一的人同时使用前路和内路开放复位术,但在每年治疗超过 50 例 DDH 的外科医生中,仅使用前路开放复位术的趋势更为明显。经验丰富的外科医生更倾向于通过术后计算机断层扫描或磁共振成像检查术中的缩窄情况。在2019年冠状病毒疾病大流行期间,DDH病例的诊断和治疗年龄没有明显变化:骨科医生对行走年龄前DDH的管理偏好主要取决于日常诊疗中儿童患者的比例和每年治疗的DDH病例数。
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引用次数: 0
Wedge osteotomy combined with internal fixation in the treatment of Mayo IIB olecranon fractures. 楔形截骨联合内固定治疗梅奥 IIB 肩胛骨骨折。
Pub Date : 2023-12-18 DOI: 10.5152/j.aott.2023.23055
Ahmet Adnan Karaarslan, Kamil Yamak

Objective: This study aimed to biomechanically compare the maximum rotational, axial movements, and compression forces between fracture fragments before and after 1-4 mm fracture site resorption among interlocking nails, compression nails, and newly designed compressive anti-resorption (CARES) nails compressed with tube and coil spring.

Methods: We determined the maximum axial/rotational movements and interfragmentary compression loads between fragments on 10 interlocking nails, 10 compression nails, and 10 CARES nails with 30 composite femurs. Using a compression-distraction testing device, 6 N·m external and internal torques were applied, and we evaluated the maximum rotational and axial displacement between fragments after 1-4 mm fracture site resorption.

Results: When 6 N·m of internal-external rotation torque was applied after 2 mm fracture site resorption, the maximum rotational displacement between fragments in the CARES nail was 3 ± 0.52 mm, 101% less than the 6.03 ± 0.83 value in the compression nail and 100% less than the 6 ± 1 mm value measured in the interlocking nail (P=.000). The compression between fragments was 298 ± 72 N in the CARES nail after 1 mm of resorption, while this value was measured as 0 in the other nails. There was a significant difference in rotational, axial stability, and interfragment compression among the different femoral nails after 1-4 mm fracture site resorption.

Conclusion: The CARES nail having additional coil springs seems significantly biomechanically superior to compression nails and interlocking nails, providing maximum rotational, axial stability, and interfragment compression after fracture site resorption.

研究目的本研究旨在从生物力学角度比较交锁钉、加压钉和新设计的用管状和螺旋弹簧加压的加压抗吸收钉(CARES)在骨折部位吸收 1-4 mm 前后骨折片间的最大旋转、轴向移动和压缩力:我们用 30 个复合股骨测定了 10 个互锁钉、10 个压缩钉和 10 个 CARES 钉上的最大轴向/旋转运动和碎片间压缩载荷。使用压缩牵引测试装置,施加 6 N-m 的外部和内部扭矩,我们评估了骨折部位吸收 1-4 mm 后碎片间的最大旋转和轴向位移:骨折部位吸收 2 mm 后,施加 6 N-m 的内外旋转扭矩时,CARES 钉中碎片间的最大旋转位移为 3 ± 0.52 mm,比压缩钉中的 6.03 ± 0.83 mm 值少 101%,比联锁钉中的 6 ± 1 mm 值少 100%(P=.000)。在吸收 1 毫米后,CARES 钉的碎片间压缩力为 298 ± 72 N,而其他钉子的测量值为 0。在骨折部位吸收 1-4 毫米后,不同股骨钉的旋转稳定性、轴向稳定性和骨折片间压缩性存在明显差异:结论:带有附加螺旋弹簧的CARES钉在生物力学方面似乎明显优于压缩钉和交锁钉,在骨折部位吸收后可提供最大的旋转稳定性、轴向稳定性和片间压缩性。
{"title":"Wedge osteotomy combined with internal fixation in the treatment of Mayo IIB olecranon fractures.","authors":"Ahmet Adnan Karaarslan, Kamil Yamak","doi":"10.5152/j.aott.2023.23055","DOIUrl":"10.5152/j.aott.2023.23055","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to biomechanically compare the maximum rotational, axial movements, and compression forces between fracture fragments before and after 1-4 mm fracture site resorption among interlocking nails, compression nails, and newly designed compressive anti-resorption (CARES) nails compressed with tube and coil spring.</p><p><strong>Methods: </strong>We determined the maximum axial/rotational movements and interfragmentary compression loads between fragments on 10 interlocking nails, 10 compression nails, and 10 CARES nails with 30 composite femurs. Using a compression-distraction testing device, 6 N·m external and internal torques were applied, and we evaluated the maximum rotational and axial displacement between fragments after 1-4 mm fracture site resorption.</p><p><strong>Results: </strong>When 6 N·m of internal-external rotation torque was applied after 2 mm fracture site resorption, the maximum rotational displacement between fragments in the CARES nail was 3 ± 0.52 mm, 101% less than the 6.03 ± 0.83 value in the compression nail and 100% less than the 6 ± 1 mm value measured in the interlocking nail (P=.000). The compression between fragments was 298 ± 72 N in the CARES nail after 1 mm of resorption, while this value was measured as 0 in the other nails. There was a significant difference in rotational, axial stability, and interfragment compression among the different femoral nails after 1-4 mm fracture site resorption.</p><p><strong>Conclusion: </strong>The CARES nail having additional coil springs seems significantly biomechanically superior to compression nails and interlocking nails, providing maximum rotational, axial stability, and interfragment compression after fracture site resorption.</p>","PeriodicalId":93854,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138815726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rim plate fixation for a rare fracture pattern of the lateral femoral condyle: A case report. 股骨外侧髁罕见骨折的边缘钢板固定术:病例报告
Pub Date : 2023-12-18 DOI: 10.5152/j.aott.2023.23108
Hanrong Xu, Ding Xu, Yinjiang Lu, Jiong Lin

Osteochondral fractures of the lateral femoral condyle caused by lateral patella dislocation have been rarely reported. The AO/OTA Classification is not suitable for this uncommon injury. Comminution of the anterior cartilage surface of the lateral condyle with bone impaction is challenging to reduce and repair accurately, leading to uncertainty in joint function recovery. The treatment for this rare fracture is not commonly reported. We, herein, report a unique case where the lateral condyle osteochondral fracture occurred alongside patellar dislocation and instability of the patellofemoral joint. Autogenous bone grafting, open reduction, and internal fixation with a rim plate resulted in a satisfactory outcome.

由髌骨外侧脱位引起的股骨外侧髁骨软骨骨折鲜有报道。AO/OTA分类法并不适用于这种不常见的损伤。股骨外侧髁前软骨表面粉碎并伴有骨质嵌塞,这对精确的减小和修复具有挑战性,导致关节功能恢复的不确定性。这种罕见骨折的治疗方法并不常见。我们在此报告了一个独特的病例,该病例的外侧髁骨软骨骨折与髌骨脱位和髌股关节不稳定同时发生。通过自体骨移植、切开复位和使用边缘钢板进行内固定,取得了令人满意的疗效。
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引用次数: 0
Wedge osteotomy combined with internal fixation in the treatment of Mayo IIB olecranon fractures. 楔形截骨联合内固定治疗梅奥 IIB 肩胛骨骨折。
Pub Date : 2023-12-18 DOI: 10.5152/j.aott.2023.23110
Youdi Xue, Shuguang Wang, Zhaohong Wang, Hongguang Song, Kun Shi

Objective: This study aimed to present the clinical outcomes and establish a safe range for olecranon wedge osteotomy combined with internal fixation in treating Mayo IIB-type olecranon fractures.

Methods: Ten consecutive patients (10 elbows) underwent treatment involving wedge osteotomy combined with internal fixation. Primary outcome measures included the evaluation of the Oxford Elbow Score (OES), Mayo Elbow Performance Score (MEPS), pain severity assessed via a visual analogue scale (VAS), elbow mobility, and the extent of osteotomy at the final follow-up.

Results: At the last follow-up, the median OES was 45 (range 38-48), and the median MEPS was 90 (range 75-100). Six out of 10 patients reported no pain based on the VAS. No significant differences were observed between the healthy and affected sides regarding flexion-extension and rotation activities. The mean horizontal lengths of the olecranon articular surface and base osteotomy were 6.2 mm (range 5.5-7.4 mm) and 14.4 mm (range 10.2-16.5 mm), respectively. The mean olecranon shortening was 4.2 mm (range 2.2-5.4 mm), resulting in a shortening rate of 7.3% to 18.9%. Fracture union was achieved in all patients, with a mean time to union of 11.2 weeks (range 8-16 weeks). Early mild (grade 1) degenerative changes were observed in 3 cases.

Conclusion: Wedge osteotomy combined with internal fixation represents a reliable treatment option for Mayo IIB olecranon fractures, particularly in cases of severe comminuted fractures that are challenging to restore anatomically.

Level of evidence: Level IV, Therapeutic Study.

目的本研究旨在展示治疗梅奥 IIB 型肩胛骨骨折的临床结果,并确定肩胛骨楔形截骨联合内固定的安全范围:连续10例患者(10个肘)接受了楔形截骨联合内固定治疗。主要结果指标包括牛津肘评分(OES)、梅奥肘关节表现评分(MEPS)、通过视觉模拟量表(VAS)评估的疼痛严重程度、肘关节活动度以及最后随访时的截骨范围:最后一次随访时,OES的中位数为45(范围为38-48),MEPS的中位数为90(范围为75-100)。根据 VAS 值,10 位患者中有 6 位表示没有疼痛感。健侧和患侧在屈伸和旋转活动方面无明显差异。肩胛骨关节面和基底截骨的平均水平长度分别为6.2毫米(范围5.5-7.4毫米)和14.4毫米(范围10.2-16.5毫米)。肩胛骨平均缩短4.2毫米(范围2.2-5.4毫米),缩短率为7.3%-18.9%。所有患者都实现了骨折愈合,平均愈合时间为 11.2 周(范围为 8-16 周)。3例患者出现了早期轻度(1级)退行性改变:结论:楔形截骨联合内固定术是治疗梅奥IIB型肩胛骨骨折的可靠方法,尤其适用于解剖复位困难的严重粉碎性骨折病例:证据级别:IV级,治疗研究。
{"title":"Wedge osteotomy combined with internal fixation in the treatment of Mayo IIB olecranon fractures.","authors":"Youdi Xue, Shuguang Wang, Zhaohong Wang, Hongguang Song, Kun Shi","doi":"10.5152/j.aott.2023.23110","DOIUrl":"10.5152/j.aott.2023.23110","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to present the clinical outcomes and establish a safe range for olecranon wedge osteotomy combined with internal fixation in treating Mayo IIB-type olecranon fractures.</p><p><strong>Methods: </strong>Ten consecutive patients (10 elbows) underwent treatment involving wedge osteotomy combined with internal fixation. Primary outcome measures included the evaluation of the Oxford Elbow Score (OES), Mayo Elbow Performance Score (MEPS), pain severity assessed via a visual analogue scale (VAS), elbow mobility, and the extent of osteotomy at the final follow-up.</p><p><strong>Results: </strong>At the last follow-up, the median OES was 45 (range 38-48), and the median MEPS was 90 (range 75-100). Six out of 10 patients reported no pain based on the VAS. No significant differences were observed between the healthy and affected sides regarding flexion-extension and rotation activities. The mean horizontal lengths of the olecranon articular surface and base osteotomy were 6.2 mm (range 5.5-7.4 mm) and 14.4 mm (range 10.2-16.5 mm), respectively. The mean olecranon shortening was 4.2 mm (range 2.2-5.4 mm), resulting in a shortening rate of 7.3% to 18.9%. Fracture union was achieved in all patients, with a mean time to union of 11.2 weeks (range 8-16 weeks). Early mild (grade 1) degenerative changes were observed in 3 cases.</p><p><strong>Conclusion: </strong>Wedge osteotomy combined with internal fixation represents a reliable treatment option for Mayo IIB olecranon fractures, particularly in cases of severe comminuted fractures that are challenging to restore anatomically.</p><p><strong>Level of evidence: </strong>Level IV, Therapeutic Study.</p>","PeriodicalId":93854,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10837603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138815727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of triple-dose-intravenous tranexamic acid on blood loss in patients undergoing total hip arthroplasty without affecting blood coagulopathy: A prospective thromboelastographic analysis. 三剂量静脉注射氨甲环酸对全髋关节置换术患者失血量而不影响凝血功能的影响:一项前瞻性血栓弹性分析。
Pub Date : 2023-11-21 DOI: 10.5152/j.aott.2023.23001
Wang-Yi Jin, Zi-Wen Yan, Xing Zhang, Sheng Pan, Chao-Ran Huang, Kai-Jin Guo, Xin Zheng

Objective: This study aimed to assess the safety and efficacy of triple-dose intravenous tranexamic acid (TXA) in patients following total hip arthroplasty (THA) using thromboelastography (TEG).

Methods: One hundred thirty patients undergoing THA were prospectively enrolled in the study. According to the intravenous infusion TXA dose, patients were divided into single-dose (n=65; mean age=60.8 ± 8.1 years) and triple-dose groups (n=65; mean age=61.8 ± 8.6 years). Complete blood count (CBC), conventional coagulation tests (CCT), and TEG were conducted 1 day before the operation, on postoperative day 1 (POD1), and postoperative day 7 (POD7). Color Doppler ultrasonography was performed 1 day before the operation and on POD7. Drainage blood loss, total blood loss (TBL), hidden blood loss (HBL), deep vein thrombosis (DVT) incidence, and blood transfusion rates were calculated and recorded. The CCT, CBC, and TEG parameters were compared between the 2 groups.

Results: Single- and triple-dose groups had significantly different hematocrit on POD7 (P < .05). No significant differences were found in CCT and hemoglobin at any corresponding time point between the 2 groups (P > .05). Despite the reaction time (R) on POD1 (P < .05), there were no significant differences in other TEG parameters at any other time point between the 2 groups (P > 0.05). For drainage blood loss and TBL, the triple-dose group had lesser blood loss than the single-dose group (P < .05). However, no significant differences were found for blood transfusion rate, HBL, or incidence of DVT (P > .05).

Conclusion: Compared with single-dose, triple-dose TXA can be more effective in decreasing blood loss without increasing DVT incidence in patients undergoing THA. Although there is a notable disparity in the R time on POD1, the administration of triple-dose TXA does not substantially impact the coagulation status as assessed by TEG and CCT.

目的:本研究旨在通过血栓弹性成像(TEG)评估全髋关节置换术(THA)后患者静脉注射三剂量氨甲环酸(TXA)的安全性和有效性。方法:130例接受人工髋关节置换术的患者被纳入前瞻性研究。根据静脉输注TXA剂量将患者分为单剂量组(n=65;平均年龄=60.8±8.1岁)和三剂量组(n=65;平均年龄=61.8±8.6岁)。术前1天、术后第1天(POD1)、术后第7天(POD7)分别进行全血细胞计数(CBC)、常规凝血试验(CCT)、TEG检测。术前1天及POD7行彩色多普勒超声检查。计算并记录引流失血量、总失血量(TBL)、隐性失血量(HBL)、深静脉血栓(DVT)发生率及输血率。比较两组患者CCT、CBC、TEG指标。结果:单剂量组和三剂量组在POD7上的红细胞压积差异有统计学意义(P < 0.05)。两组患者CCT、血红蛋白各时间点比较差异均无统计学意义(P < 0.05)。两组间除POD1反应时间(R)差异有统计学意义(P < 0.05)外,其他各时间点TEG参数差异无统计学意义(P < 0.05)。引流失血量和TBL方面,三剂量组的失血量低于单剂量组(P < 0.05)。然而,输血率、HBL或DVT发生率无显著差异(P < 0.05)。结论:与单剂量相比,三剂量TXA能更有效地减少THA患者的失血量而不增加DVT的发生率。虽然在POD1的R时间上存在显著差异,但根据TEG和CCT评估,三剂量TXA的施用对凝血状态没有实质性影响。
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引用次数: 0
A new femur intramedullary nail with tube and coil spring for maximum interfragmentary rotational and axial stability after fracture site resorption. 一种新型股骨髓内钉,带有钢管和螺旋弹簧,可在骨折部位吸收后实现最大的节间旋转和轴向稳定性。
Pub Date : 2023-11-01 DOI: 10.5152/j.aott.2023.23055
Ahmet Adnan Karaarslan, Kamil Yamak

Objective: This study aimed to biomechanically compare the maximum rotational, axial movements, and compression forces between fracture fragments before and after 1-4 mm fracture site resorption among interlocking nails, compression nails, and newly designed compressive anti-resorption (CARES) nails compressed with tube and coil spring.

Methods: We determined the maximum axial/rotational movements and interfragmentary compression loads between fragments on 10 interlocking nails, 10 compression nails, and 10 CARES nails with 30 composite femurs. Using a compression-distraction testing device, 6 N·m external and internal torques were applied, and we evaluated the maximum rotational and axial displacement between fragments after 1-4 mm fracture site resorption.

Results: When 6 N·m of internal-external rotation torque was applied after 2 mm fracture site resorption, the maximum rotational displacement between fragments in the CARES nail was 3 ± 0.52 mm, 101% less than the 6.03 ± 0.83 value in the compression nail and 100% less than the 6 ± 1 mm value measured in the interlocking nail (P=.000). The compression between fragments was 298 ± 72 N in the CARES nail after 1 mm of resorption, while this value was measured as 0 in the other nails. There was a significant difference in rotational, axial stability, and interfragment compression among the different femoral nails after 1-4 mm fracture site resorption.

Conclusion: The CARES nail having additional coil springs seems significantly biomechanically superior to compression nails and interlocking nails, providing maximum rotational, axial stability, and interfragment compression after fracture site resorption.

研究目的本研究旨在从生物力学角度比较交锁钉、加压钉和新设计的用管状和螺旋弹簧加压的加压抗吸收钉(CARES)在骨折部位吸收 1-4 mm 前后骨折片间的最大旋转、轴向移动和压缩力:我们用 30 个复合股骨测定了 10 个互锁钉、10 个压缩钉和 10 个 CARES 钉上的最大轴向/旋转运动和碎片间压缩载荷。使用压缩牵引测试装置,施加 6 N-m 的外部和内部扭矩,我们评估了骨折部位吸收 1-4 mm 后碎片间的最大旋转和轴向位移:骨折部位吸收 2 mm 后,施加 6 N-m 的内外旋转扭矩时,CARES 钉中碎片间的最大旋转位移为 3 ± 0.52 mm,比压缩钉中的 6.03 ± 0.83 mm 值少 101%,比联锁钉中的 6 ± 1 mm 值少 100%(P=.000)。在吸收 1 毫米后,CARES 钉的碎片间压缩力为 298 ± 72 N,而其他钉子的测量值为 0。在骨折部位吸收 1-4 毫米后,不同股骨钉的旋转稳定性、轴向稳定性和骨折片间压缩性存在明显差异:结论:带有附加螺旋弹簧的CARES钉在生物力学方面似乎明显优于压缩钉和交锁钉,在骨折部位吸收后可提供最大的旋转稳定性、轴向稳定性和片间压缩性。
{"title":"A new femur intramedullary nail with tube and coil spring for maximum interfragmentary rotational and axial stability after fracture site resorption.","authors":"Ahmet Adnan Karaarslan, Kamil Yamak","doi":"10.5152/j.aott.2023.23055","DOIUrl":"10.5152/j.aott.2023.23055","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to biomechanically compare the maximum rotational, axial movements, and compression forces between fracture fragments before and after 1-4 mm fracture site resorption among interlocking nails, compression nails, and newly designed compressive anti-resorption (CARES) nails compressed with tube and coil spring.</p><p><strong>Methods: </strong>We determined the maximum axial/rotational movements and interfragmentary compression loads between fragments on 10 interlocking nails, 10 compression nails, and 10 CARES nails with 30 composite femurs. Using a compression-distraction testing device, 6 N·m external and internal torques were applied, and we evaluated the maximum rotational and axial displacement between fragments after 1-4 mm fracture site resorption.</p><p><strong>Results: </strong>When 6 N·m of internal-external rotation torque was applied after 2 mm fracture site resorption, the maximum rotational displacement between fragments in the CARES nail was 3 ± 0.52 mm, 101% less than the 6.03 ± 0.83 value in the compression nail and 100% less than the 6 ± 1 mm value measured in the interlocking nail (P=.000). The compression between fragments was 298 ± 72 N in the CARES nail after 1 mm of resorption, while this value was measured as 0 in the other nails. There was a significant difference in rotational, axial stability, and interfragment compression among the different femoral nails after 1-4 mm fracture site resorption.</p><p><strong>Conclusion: </strong>The CARES nail having additional coil springs seems significantly biomechanically superior to compression nails and interlocking nails, providing maximum rotational, axial stability, and interfragment compression after fracture site resorption.</p>","PeriodicalId":93854,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"57 6","pages":"372-377"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10837580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Destructive disasters, trauma, crush syndrome, and beyond. 破坏性灾害、创伤、挤压综合症及其他。
Pub Date : 2023-11-01 DOI: 10.5152/j.aott.2023.23147
Mehmet Sükrü Sever, Yusuf Alper Katı, Ufuk Özkaya

Orthopedic injuries, especially fractures of long bones as well as multiple fractures and comminuted fractures, are very common after destructive disasters (e.g., earthquakes, wars, and hurricanes). Another frequent problem is traumatic rhabdomyolysis, which may result in crush syndrome, the second most frequent cause of death after direct traumatic impact following earthquakes. To improve outcomes, interventions should be initiated even before extrication of the victims, which include maintenance of airway patency and spine stabilization, stopping traumatic bleeding by any means, and initiating fluid resuscitation. On-site amputations have been extensively debated to liberate the victims if the release of trapped limbs is impossible. Early after the rescue, a primary survey and triage are performed, a fluid resuscitation policy is planned, complications are treated, the wounds are decontaminated, and the victim is transported to specialized hospitals. A triage and primary survey are also performed at admission to the hospitals, which are followed by a secondary survey, physical, laboratory, and imaging examinations. Washing and cleaning of the soft-tissue injuries and debridement in open, necrotic wounds are vital. Applications of fasciotomies and amputations are controversial since they are associated with both benefits and serious complications; therefore, clear indications should be defined. Crush syndrome has been described as the presence of systemic manifestations following traumatic rhabdomyolysis, the most important component of which is acute kidney injury that may contribute to fatal hyperkalemia. The overall mortality rate is around 20% in crushed patients, which underlines the importance of prevention. Treatment includes maintaining of fluid electrolyte and acid-base balance, application of dialysis, and also prevention and treatment of complications. The principles and practices in disaster medicine may differ from those applied in routine practice; therefore, organizing repeated training courses may be helpful to provide the most effective healthcare and to save as many lives as possible after mass disasters.

骨科损伤,尤其是长骨骨折以及多发性骨折和粉碎性骨折,在破坏性灾害(如地震、战争和飓风)后非常常见。另一个常见问题是外伤性横纹肌溶解症,它可能导致挤压综合征,是地震后仅次于直接外伤冲击的第二大死亡原因。为改善预后,甚至在救出受害者之前就应启动干预措施,其中包括保持呼吸道通畅和脊柱稳定,通过各种方法止住创伤出血,并启动液体复苏。在无法释放被困肢体的情况下,现场截肢以解救遇难者的方法已引起广泛讨论。救援结束后,应尽早进行初步调查和分流,制定液体复苏政策,治疗并发症,对伤口进行消毒,并将受害者送往专科医院。入院时也要进行分诊和初步检查,然后进行二次检查、体格检查、实验室检查和影像学检查。软组织损伤的清洗和清理以及开放性坏死伤口的清创至关重要。筋膜切开术和截肢术的应用是有争议的,因为它们既有好处,也有严重的并发症;因此,应明确界定适应症。挤压综合征被描述为创伤性横纹肌溶解后出现的全身表现,其中最重要的组成部分是急性肾损伤,可能导致致命的高钾血症。挤压伤患者的总死亡率约为 20%,这就强调了预防的重要性。治疗包括维持液体电解质和酸碱平衡、进行透析以及预防和治疗并发症。灾难医学的原则和实践可能不同于日常实践,因此,组织重复培训课程可能有助于在大规模灾难后提供最有效的医疗保健服务并尽可能多地挽救生命。
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引用次数: 0
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Acta orthopaedica et traumatologica turcica
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