Jorge Nara-Sauceda, Mario Moreno-Pacheco, Jesica Patiño-García
Objective: To determine the clinical-epidemiological characteristics, diagnostic feasibility of home respiratory polygraphy and treatment of patients with suspected obstructive sleep apnea (OSA) at cardiovascular risk.
Methods: An observational, cross-sectional, descriptive study was conducted in patients seen in a cardiology outpatient service with suspected OSA, from January 2015 to December 2019. The information was obtained from medical records, and a descriptive statistical analysis was applied to this information.
Results: 138 files were reviewed; only 8% of the home respiratory polygraphs were discarded, because they did not meet the required quality standards. It was demonstrated that 89% suffered from OSA, 60% moderate to severe; in men after 50 years of age. The main cardiovascular risk factors was hypertension (89%). The most prevalent heart disease was hypertension (52%). Cardiovascular pharmacological treatment was improved in 82% of the cases. Cardiac rehabilitation in 30%, noninvasive mechanical ventilation 41%, fixed modality 33%, and self-adjustable 9%, all with telemetry.
Conclusions: The prevalence and severity of OSA is higher in the presence of risk or established cardiovascular disease. In the presence of clinical suspicion, it is feasible to confirm the diagnosis with home respiratory poligrafy due to the level of precision and the lower infrastructure required. Greater involvement of the cardiologist in the diagnosis and treatment of this disorder is necessary due to the significant risk of cardiovascular disease it represents.
{"title":"[Obstructive sleep apnea in cardiology clinical practice. Epidemiology, diagnosis, and treatment. Observational, cross-sectional, retrospective study].","authors":"Jorge Nara-Sauceda, Mario Moreno-Pacheco, Jesica Patiño-García","doi":"10.24875/ACM.23000078","DOIUrl":"10.24875/ACM.23000078","url":null,"abstract":"<p><strong>Objective: </strong>To determine the clinical-epidemiological characteristics, diagnostic feasibility of home respiratory polygraphy and treatment of patients with suspected obstructive sleep apnea (OSA) at cardiovascular risk.</p><p><strong>Methods: </strong>An observational, cross-sectional, descriptive study was conducted in patients seen in a cardiology outpatient service with suspected OSA, from January 2015 to December 2019. The information was obtained from medical records, and a descriptive statistical analysis was applied to this information.</p><p><strong>Results: </strong>138 files were reviewed; only 8% of the home respiratory polygraphs were discarded, because they did not meet the required quality standards. It was demonstrated that 89% suffered from OSA, 60% moderate to severe; in men after 50 years of age. The main cardiovascular risk factors was hypertension (89%). The most prevalent heart disease was hypertension (52%). Cardiovascular pharmacological treatment was improved in 82% of the cases. Cardiac rehabilitation in 30%, noninvasive mechanical ventilation 41%, fixed modality 33%, and self-adjustable 9%, all with telemetry.</p><p><strong>Conclusions: </strong>The prevalence and severity of OSA is higher in the presence of risk or established cardiovascular disease. In the presence of clinical suspicion, it is feasible to confirm the diagnosis with home respiratory poligrafy due to the level of precision and the lower infrastructure required. Greater involvement of the cardiologist in the diagnosis and treatment of this disorder is necessary due to the significant risk of cardiovascular disease it represents.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"141-150"},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Congenital heart disease is the most common birth defect and the leading cause of childhood mortality in high-income countries. In these countries, the prognosis for a child born with congenital heart disease is excellent, with over 90% achieving adulthood. However, in the low and lower-middle-income countries, as ours, the outlook is starkly different. In Chiapas, because of the progress of the hemodynamics program, more and more types of congenital heart diseases are susceptible to being treated by cardiac catheterization.
Objective: To show the global experience of the interventionism in congenital heart diseases in Chiapas from its inception to recent days.
Method: Through a retrospective study from April 2016 to June 2023, we reviewed the electronic files of the total of patients who underwent cardiac catheterism during the same period of time.
Results: A total of 1000 procedures were performed, 581 in female patients, with a median age of 4 years (1 day to 77 years). Of the total procedures, 115 (11.5%) were diagnostic catheterizations and 885 (88.5%) were interventional.
Conclusions: Cardiac catheterization in pediatrics in Chiapas has displaced cardiac surgery in a large percentage, and the results that have been obtained are undoubtedly encouraging, which already represents a decentralization in the care of congenital heart diseases in our country.
{"title":"[Interventionism in congenital heart disease in Chiapas. The history after thousand cases performed].","authors":"Roberto Mijangos-Vázquez, Rogelio Hernández-Reyes","doi":"10.24875/ACM.23000170","DOIUrl":"10.24875/ACM.23000170","url":null,"abstract":"<p><strong>Background: </strong>Congenital heart disease is the most common birth defect and the leading cause of childhood mortality in high-income countries. In these countries, the prognosis for a child born with congenital heart disease is excellent, with over 90% achieving adulthood. However, in the low and lower-middle-income countries, as ours, the outlook is starkly different. In Chiapas, because of the progress of the hemodynamics program, more and more types of congenital heart diseases are susceptible to being treated by cardiac catheterization.</p><p><strong>Objective: </strong>To show the global experience of the interventionism in congenital heart diseases in Chiapas from its inception to recent days.</p><p><strong>Method: </strong>Through a retrospective study from April 2016 to June 2023, we reviewed the electronic files of the total of patients who underwent cardiac catheterism during the same period of time.</p><p><strong>Results: </strong>A total of 1000 procedures were performed, 581 in female patients, with a median age of 4 years (1 day to 77 years). Of the total procedures, 115 (11.5%) were diagnostic catheterizations and 885 (88.5%) were interventional.</p><p><strong>Conclusions: </strong>Cardiac catheterization in pediatrics in Chiapas has displaced cardiac surgery in a large percentage, and the results that have been obtained are undoubtedly encouraging, which already represents a decentralization in the care of congenital heart diseases in our country.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"300-308"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan P Costabel, Miguel Quintana, Joaquín Perea, Pablo Lamelas, Alfonsina Candiello, Patricio Sanhueza, Alexandra Arias-Mendoza, Iván Saavedra, Alex Rivera-Toquica, Marildes L de Castro, Manuel Álvarez-Gaviria, Jorge Belardi, Ángel Cequier, Álvaro Sosa-Liprandi, Ricardo Villarreal
The treatment of ST-segment elevation myocardial infarction has barriers depending on the geographic region. Primary coronary angioplasty is the treatment of choice, if it is performed on time and by experienced operators. However, when it is not available, the administration of fibrinolysis and referral for rescue angioplasty, in case of negative reperfusion, is the best strategy. In the same way, coronary angioplasty, as part of a pharmacoinvasive strategy, is the best alternative when there is positive reperfusion. The development of infarct treatment networks increases the number of patients reperfused within the recommended times and improves outcomes. In Latin America, national myocardial infarction treatment programs should focus on improving outcomes, and long-term success depends on working toward defined goals and enhancing functionality, therefore programs should develop capacity to measure their performance. The following document discusses all of these alternatives and suggests opportunities for improvement.
ST 段抬高型心肌梗死的治疗因地域不同而存在障碍。原发性冠状动脉血管成形术是首选的治疗方法,但必须由经验丰富的操作人员及时实施。但是,如果不能及时进行冠状动脉成形术,最好的办法是进行纤维蛋白溶解术,并在再灌注不良的情况下转诊进行抢救性血管成形术。同样,作为药物介入策略的一部分,冠状动脉血管成形术也是再灌注阳性情况下的最佳选择。心梗治疗网络的发展增加了在建议时间内再灌注的患者人数,并改善了治疗效果。在拉丁美洲,国家心肌梗死治疗计划应将重点放在改善预后上,长期的成功取决于努力实现既定目标和增强功能,因此计划应发展衡量其绩效的能力。以下文件讨论了所有这些替代方案,并提出了改进建议。
{"title":"[Position statement for improvement in reperfusion of ST-elevation myocardial infarction in Latin America].","authors":"Juan P Costabel, Miguel Quintana, Joaquín Perea, Pablo Lamelas, Alfonsina Candiello, Patricio Sanhueza, Alexandra Arias-Mendoza, Iván Saavedra, Alex Rivera-Toquica, Marildes L de Castro, Manuel Álvarez-Gaviria, Jorge Belardi, Ángel Cequier, Álvaro Sosa-Liprandi, Ricardo Villarreal","doi":"10.24875/ACM.23000045","DOIUrl":"10.24875/ACM.23000045","url":null,"abstract":"<p><p>The treatment of ST-segment elevation myocardial infarction has barriers depending on the geographic region. Primary coronary angioplasty is the treatment of choice, if it is performed on time and by experienced operators. However, when it is not available, the administration of fibrinolysis and referral for rescue angioplasty, in case of negative reperfusion, is the best strategy. In the same way, coronary angioplasty, as part of a pharmacoinvasive strategy, is the best alternative when there is positive reperfusion. The development of infarct treatment networks increases the number of patients reperfused within the recommended times and improves outcomes. In Latin America, national myocardial infarction treatment programs should focus on improving outcomes, and long-term success depends on working toward defined goals and enhancing functionality, therefore programs should develop capacity to measure their performance. The following document discusses all of these alternatives and suggests opportunities for improvement.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"208-218"},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139479497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eugenio Flamand Rodríguez, in memoriam.","authors":"Alejandro Martín-Trenor","doi":"10.24875/ACM.23000257","DOIUrl":"10.24875/ACM.23000257","url":null,"abstract":"","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"94 3","pages":"401"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabel C Sánchez-Escobar, Silvia J Galvis-Blanco, Luis H Díaz-Medina, Rafael Correa-Velásquez, Rafael Lince-Varela
Background: Ascending aortic aneurysms are rare pathologies in childhood, especially in the absence of previous diseases such as Marfan syndrome.
Objective: Present the possibility of successful endovascular management of large vessel aneurysms, using stents and microcatheters with embolization of the aneurysm sac.
Method: We present the case of a previously healthy ten-year-old patient, in whom a pseudoaneurysm was documented between the origin of the left common carotid artery and left subclavian artery, successfully managed endovascularly, initially with a stent covering the neck of the aneurysm to remodel it and later with embolization of the aneurysm sac using a microcatheter.
Results: Aneurysms of large vessels, such common carotid artery and subclavian artery, are at risk of rupture with devastating complications; endovascular management is considered a minimally invasive management option, with favorable results.
Conclusion: The endovascular management of large vessel aneurysms using stents and microcatheters with embolization of the aneurysmal sac is a novel management option that achieves successful results.
{"title":"Successful endovascular treatment of aortic arch aneurysm in a pediatric patient.","authors":"Isabel C Sánchez-Escobar, Silvia J Galvis-Blanco, Luis H Díaz-Medina, Rafael Correa-Velásquez, Rafael Lince-Varela","doi":"10.24875/ACM.22000272","DOIUrl":"10.24875/ACM.22000272","url":null,"abstract":"<p><strong>Background: </strong>Ascending aortic aneurysms are rare pathologies in childhood, especially in the absence of previous diseases such as Marfan syndrome.</p><p><strong>Objective: </strong>Present the possibility of successful endovascular management of large vessel aneurysms, using stents and microcatheters with embolization of the aneurysm sac.</p><p><strong>Method: </strong>We present the case of a previously healthy ten-year-old patient, in whom a pseudoaneurysm was documented between the origin of the left common carotid artery and left subclavian artery, successfully managed endovascularly, initially with a stent covering the neck of the aneurysm to remodel it and later with embolization of the aneurysm sac using a microcatheter.</p><p><strong>Results: </strong>Aneurysms of large vessels, such common carotid artery and subclavian artery, are at risk of rupture with devastating complications; endovascular management is considered a minimally invasive management option, with favorable results.</p><p><strong>Conclusion: </strong>The endovascular management of large vessel aneurysms using stents and microcatheters with embolization of the aneurysmal sac is a novel management option that achieves successful results.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"94 1","pages":"48-54"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140178206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandro Ezquerra-Osorio, David A Brenes-Castro, Ramón Espinosa-Soto, Jorge L Vargas-Estrada, Rodrigo Cue-Sierra, Alexandra Arias-Mendoza, Diego Araiza-Garaygordobil
{"title":"A rare presentation of Takotsubo syndrome and transient dilated cardiomyopathy due to severe hypocalcemia.","authors":"Alejandro Ezquerra-Osorio, David A Brenes-Castro, Ramón Espinosa-Soto, Jorge L Vargas-Estrada, Rodrigo Cue-Sierra, Alexandra Arias-Mendoza, Diego Araiza-Garaygordobil","doi":"10.24875/ACM.23000248","DOIUrl":"https://doi.org/10.24875/ACM.23000248","url":null,"abstract":"","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"94 4","pages":"502-505"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudia A Pavón-Flores, Leonardo Rivera-Rodríguez, Juan E Calderón-Colmenero
{"title":"Pompe disease: a lesson to learn.","authors":"Claudia A Pavón-Flores, Leonardo Rivera-Rodríguez, Juan E Calderón-Colmenero","doi":"10.24875/ACM.23000139","DOIUrl":"https://doi.org/10.24875/ACM.23000139","url":null,"abstract":"","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"94 4","pages":"529-530"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariela Mouratian, Claudia Villalba, Agustina Ramos, Fernando Diez-Mori, M ª Victoria Lafuente, Erica Stelmaszewski, Carla Pasinato, Juliana Medina, Marisa Di Santo, Pablo García-Delucis
Objectives: Ebstein's anomaly is a congenital defect characterized by a lack of delamination and apical displacement of the tricuspid valve, tricuspid insufficiency, right atrial enlargement, and ventricular dysfunction. To analyze the results and evolution of the different surgical strategies, data were collected from 45 patients operated on during 1990-2018. Twenty-six patients were included with a median age at initial surgery of 11.3 years (range: 13 days-18.6 years).
Method: Procedures were plastic 10 patients (38%), cone technique reconstruction 11 (42%), and replacement 5 (19%). Additional interventions were required in 7 patients: cavo-pulmonary anastomosis 4 and Cox-maze 4. Nine patients (34.6%) required reoperation due to severe tricuspid insufficiency. Six had previous plastic, two bioprothesis, and one, cone.
Results: Overall mortality was 11.5% (3) at a median of 10.1 years post-surgery (range: 5.7-10.12) associated with arrhythmias (p = 0.05), right (p = 0.008), left (p = 0.0001) ventricular dysfunction and reoperations (p = 0.03). None were previous conus. Median follow-up was 6.5 years (range: 1-29.1). Ninety-one-point-six percent were in functional class I/II and 79.2% in sinus rhythm.
Conclusions: The results of the different classic techniques were similar, although not free of complications and reoperations. Cone reconstruction proved to be effective, with low surgical mortality, less need for reoperations, and durability in the medium term.
{"title":"Surgical strategies in Ebstein anomaly: 28 years' experience in a pediatric hospital.","authors":"Mariela Mouratian, Claudia Villalba, Agustina Ramos, Fernando Diez-Mori, M ª Victoria Lafuente, Erica Stelmaszewski, Carla Pasinato, Juliana Medina, Marisa Di Santo, Pablo García-Delucis","doi":"10.24875/ACM.23000203","DOIUrl":"10.24875/ACM.23000203","url":null,"abstract":"<p><strong>Objectives: </strong>Ebstein's anomaly is a congenital defect characterized by a lack of delamination and apical displacement of the tricuspid valve, tricuspid insufficiency, right atrial enlargement, and ventricular dysfunction. To analyze the results and evolution of the different surgical strategies, data were collected from 45 patients operated on during 1990-2018. Twenty-six patients were included with a median age at initial surgery of 11.3 years (range: 13 days-18.6 years).</p><p><strong>Method: </strong>Procedures were plastic 10 patients (38%), cone technique reconstruction 11 (42%), and replacement 5 (19%). Additional interventions were required in 7 patients: cavo-pulmonary anastomosis 4 and Cox-maze 4. Nine patients (34.6%) required reoperation due to severe tricuspid insufficiency. Six had previous plastic, two bioprothesis, and one, cone.</p><p><strong>Results: </strong>Overall mortality was 11.5% (3) at a median of 10.1 years post-surgery (range: 5.7-10.12) associated with arrhythmias (p = 0.05), right (p = 0.008), left (p = 0.0001) ventricular dysfunction and reoperations (p = 0.03). None were previous conus. Median follow-up was 6.5 years (range: 1-29.1). Ninety-one-point-six percent were in functional class I/II and 79.2% in sinus rhythm.</p><p><strong>Conclusions: </strong>The results of the different classic techniques were similar, although not free of complications and reoperations. Cone reconstruction proved to be effective, with low surgical mortality, less need for reoperations, and durability in the medium term.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"94 4","pages":"403-411"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge A Ortega-Hernández, Mario R García-Arias, Jardiel Argüello-Bolaños, Manlio F Márquez-Murillo, Rodrigo Gopar-Nieto, Ángel A Priego-Ranero, Daniel Sierra-Lara-Martínez
Objectives: Arrhythmogenic cardiomyopathy (ACM) is a complex cardiac disorder associated with ventricular arrhythmias. Understanding the relationship between mechanical uncoupling and cardiac structural changes in ACM patients is crucial for improved risk stratification and management.
Methods: In this study, we enrolled 25 ACM patients (median age 34 years, 72% men) based on the 2019 Modified Task Force and Padua criteria. Patients were categorized by the presence or absence of clinically relevant ventricular tachycardia (crVT), necessitating emergency interventions. Right ventricular-arterial coupling (VAC) was assessed using echocardiography. Low-rank regression splines were employed to model left ventricular ejection fraction (LVEF) and right ventricular ejection fraction (RVEF) in relation to VAC.
Results: Positive associations were observed between VAC and LVEF (ρ = 0.472, p = 0.023), RVEF (ρ = 0.522, p = 0.038), and right ventricular (RV) indexed stroke volume (ρ = 0.79, p < 0.001). Patients with crVT exhibited correlations with RV shortening, reduced RVEF (39.6 vs. 32.2%, p = 0.025), increased left ventricular (LV) mass (38.99 vs. 45.55, p = 0.045), and LV end-diastolic volume (LVEDV) (56.99 vs. 68.15 mL/m2, p = 0.045). Positive associations for VAC were noted with LVEDV (p = 0.039) and LV mass (p = 0.039), while negative correlations were observed with RVEF by CMR (p = 0.023) and RV shortening by echocardiography (p = 0.026).
Conclusions: Our findings underscore the significance of right VAC in ACM, demonstrating correlations with RV and LVEF, RV stroke volume, and clinically relevant arrhythmias. Insights into RVEF, LV mass, and end-diastolic volume provide valuable contributions to the understanding of ACM pathophysiology and may inform risk assessment strategies.
{"title":"Mechanical and electrical uncoupling: the role of cardiac magnetic resonance imaging in arrhythmogenic cardiomyopathy. Proof of concept.","authors":"Jorge A Ortega-Hernández, Mario R García-Arias, Jardiel Argüello-Bolaños, Manlio F Márquez-Murillo, Rodrigo Gopar-Nieto, Ángel A Priego-Ranero, Daniel Sierra-Lara-Martínez","doi":"10.24875/ACM.23000199","DOIUrl":"10.24875/ACM.23000199","url":null,"abstract":"<p><strong>Objectives: </strong>Arrhythmogenic cardiomyopathy (ACM) is a complex cardiac disorder associated with ventricular arrhythmias. Understanding the relationship between mechanical uncoupling and cardiac structural changes in ACM patients is crucial for improved risk stratification and management.</p><p><strong>Methods: </strong>In this study, we enrolled 25 ACM patients (median age 34 years, 72% men) based on the 2019 Modified Task Force and Padua criteria. Patients were categorized by the presence or absence of clinically relevant ventricular tachycardia (crVT), necessitating emergency interventions. Right ventricular-arterial coupling (VAC) was assessed using echocardiography. Low-rank regression splines were employed to model left ventricular ejection fraction (LVEF) and right ventricular ejection fraction (RVEF) in relation to VAC.</p><p><strong>Results: </strong>Positive associations were observed between VAC and LVEF (ρ = 0.472, p = 0.023), RVEF (ρ = 0.522, p = 0.038), and right ventricular (RV) indexed stroke volume (ρ = 0.79, p < 0.001). Patients with crVT exhibited correlations with RV shortening, reduced RVEF (39.6 vs. 32.2%, p = 0.025), increased left ventricular (LV) mass (38.99 vs. 45.55, p = 0.045), and LV end-diastolic volume (LVEDV) (56.99 vs. 68.15 mL/m<sup>2</sup>, p = 0.045). Positive associations for VAC were noted with LVEDV (p = 0.039) and LV mass (p = 0.039), while negative correlations were observed with RVEF by CMR (p = 0.023) and RV shortening by echocardiography (p = 0.026).</p><p><strong>Conclusions: </strong>Our findings underscore the significance of right VAC in ACM, demonstrating correlations with RV and LVEF, RV stroke volume, and clinically relevant arrhythmias. Insights into RVEF, LV mass, and end-diastolic volume provide valuable contributions to the understanding of ACM pathophysiology and may inform risk assessment strategies.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"94 3","pages":"269-275"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesús De Rubens-Figueroa, Joanna Granda-Jiménez, Alfonso Hoyos-Apodaca, Flora Zárate-Mondragón
{"title":"Contrast echocardiogram for diagnosis to pulmonary arterio-venous fistulas in hepato-pulmonary syndrome.","authors":"Jesús De Rubens-Figueroa, Joanna Granda-Jiménez, Alfonso Hoyos-Apodaca, Flora Zárate-Mondragón","doi":"10.24875/ACM.22000260","DOIUrl":"10.24875/ACM.22000260","url":null,"abstract":"","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"94 1","pages":"107-110"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140178138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}