Pub Date : 2025-12-19DOI: 10.1016/j.clgc.2025.102492
Arantza Sanvisens, Jan Trallero, Aina Romaguera, Montse Puigdemont, Anna Vidal-Vila, Josep Comet-Batlle, Rafael Marcos-Gragera, Bernat Carles Serdà-Ferrer
Purpose: The aim of this study is to determine the incidence of prostate cancer (PC) and its trends according to the age, Gleason grade (GG) and stage.
Methods: Population-based study of PC cases diagnosed in Girona, Spain, from 2010 to 2021. Age at diagnosis, date and method of diagnosis, histology, Gleason score, and stage at diagnosis were collected. Poisson and negative binomial generalized linear models were used to estimate incidence trends and incidence rate ratios (IRRs), respectively.
Results: Five thousand three hundred nine cases were included, with a median age of 70 years (IQR:64-77). The age standardized rates according to GG ranged from 12.8 cases per 100,000 men-year (m-y) for GG 5 to 36.6 cases for GG 2 and from 19.9 to 52.6 cases per 100,000 m-y for stages IV and II, respectively. Overall, there was a decline between 2010 and 2014, with an annual percentage change (APC) of -6.1% (95% CI, -9.0, -3.1), followed by stabilisation (APC: -0.3% [95% CI, -2.1, 1.5]). Adjusted IRRs for GG 3, 4, and 5 were lower than GG 1 and IRRs for stages III and IV were lower than stage I; however, the IRR for stage II was higher (IRR = 1.53 [95% CI, 1.40, 1.67]).
Conclusions: Although the overall incidence of PC has remained stable since 2014, there has been an increase in cases with the worst prognosis. These cases usually involve elderly patients, who are the most vulnerable.
{"title":"Prostate Cancer Incidence by Age and Clinicopathological Characteristics: A Population-Based Study in Girona, Spain, 2010 to 2021.","authors":"Arantza Sanvisens, Jan Trallero, Aina Romaguera, Montse Puigdemont, Anna Vidal-Vila, Josep Comet-Batlle, Rafael Marcos-Gragera, Bernat Carles Serdà-Ferrer","doi":"10.1016/j.clgc.2025.102492","DOIUrl":"https://doi.org/10.1016/j.clgc.2025.102492","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to determine the incidence of prostate cancer (PC) and its trends according to the age, Gleason grade (GG) and stage.</p><p><strong>Methods: </strong>Population-based study of PC cases diagnosed in Girona, Spain, from 2010 to 2021. Age at diagnosis, date and method of diagnosis, histology, Gleason score, and stage at diagnosis were collected. Poisson and negative binomial generalized linear models were used to estimate incidence trends and incidence rate ratios (IRRs), respectively.</p><p><strong>Results: </strong>Five thousand three hundred nine cases were included, with a median age of 70 years (IQR:64-77). The age standardized rates according to GG ranged from 12.8 cases per 100,000 men-year (m-y) for GG 5 to 36.6 cases for GG 2 and from 19.9 to 52.6 cases per 100,000 m-y for stages IV and II, respectively. Overall, there was a decline between 2010 and 2014, with an annual percentage change (APC) of -6.1% (95% CI, -9.0, -3.1), followed by stabilisation (APC: -0.3% [95% CI, -2.1, 1.5]). Adjusted IRRs for GG 3, 4, and 5 were lower than GG 1 and IRRs for stages III and IV were lower than stage I; however, the IRR for stage II was higher (IRR = 1.53 [95% CI, 1.40, 1.67]).</p><p><strong>Conclusions: </strong>Although the overall incidence of PC has remained stable since 2014, there has been an increase in cases with the worst prognosis. These cases usually involve elderly patients, who are the most vulnerable.</p>","PeriodicalId":93941,"journal":{"name":"Clinical genitourinary cancer","volume":" ","pages":"102492"},"PeriodicalIF":2.7,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.clgc.2024.01.021
L. Brink, A. Ruiter, B. Lagerveld, N. Graafland, A. Bex, H. Beerlage, R.J.M. van Moorselaar, P. Zondervan
{"title":"The impact of a multidisciplinary tumour board (MTB) on treatment decision making for patients with renal cell carcinoma (RCC): 5-year data analysis","authors":"L. Brink, A. Ruiter, B. Lagerveld, N. Graafland, A. Bex, H. Beerlage, R.J.M. van Moorselaar, P. Zondervan","doi":"10.1016/j.clgc.2024.01.021","DOIUrl":"https://doi.org/10.1016/j.clgc.2024.01.021","url":null,"abstract":"","PeriodicalId":93941,"journal":{"name":"Clinical genitourinary cancer","volume":"327 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139822790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.clgc.2024.02.006
Margaret Meagher, Kylie M. Morgan, Leah N. Deshler, Dhruv Puri, Kit Yuen, Aditya Bagrodia, Brent Rose, Tyler F Stewart, A. Salmasi
{"title":"The Role of Radical Cystectomy in Clinically Node Positive Bladder Cancer: A US Veterans Health Administration Study","authors":"Margaret Meagher, Kylie M. Morgan, Leah N. Deshler, Dhruv Puri, Kit Yuen, Aditya Bagrodia, Brent Rose, Tyler F Stewart, A. Salmasi","doi":"10.1016/j.clgc.2024.02.006","DOIUrl":"https://doi.org/10.1016/j.clgc.2024.02.006","url":null,"abstract":"","PeriodicalId":93941,"journal":{"name":"Clinical genitourinary cancer","volume":"76 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139887499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.clgc.2024.01.019
Jose C. Tapia, Freya Bosma, J. Gavira, Sofia Sanchez, Maria Alejandra Molina, J. Sanz-Beltran, Cristina Martín-Lorente, G. Anguera, Pablo Maroto
{"title":"Treatment patterns and survival outcomes before and after access to immune checkpoint inhibitors for patients with metastatic urothelial carcinoma: A single-centre retrospective study from 2004 to 2021.","authors":"Jose C. Tapia, Freya Bosma, J. Gavira, Sofia Sanchez, Maria Alejandra Molina, J. Sanz-Beltran, Cristina Martín-Lorente, G. Anguera, Pablo Maroto","doi":"10.1016/j.clgc.2024.01.019","DOIUrl":"https://doi.org/10.1016/j.clgc.2024.01.019","url":null,"abstract":"","PeriodicalId":93941,"journal":{"name":"Clinical genitourinary cancer","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139815806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.clgc.2024.02.002
S. Yajima, Y. Nakanishi, Ryo Andy Ogasawara, Naoki Imasato, Kohei Hirose, Sao Katsumura, M. Kataoka, H. Masuda
{"title":"Value of Cystatin C-Based Sarcopenia Index in Patients Undergoing Surgery for Renal Tumors","authors":"S. Yajima, Y. Nakanishi, Ryo Andy Ogasawara, Naoki Imasato, Kohei Hirose, Sao Katsumura, M. Kataoka, H. Masuda","doi":"10.1016/j.clgc.2024.02.002","DOIUrl":"https://doi.org/10.1016/j.clgc.2024.02.002","url":null,"abstract":"","PeriodicalId":93941,"journal":{"name":"Clinical genitourinary cancer","volume":"56 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139829352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.clgc.2024.02.004
V. Noronha, Venkatesh Kapu, Amit Joshi, N. Menon, Ajay Singh, G. Prakash, S. Menon, N. Sable, V. Murthy, M. Pal, Amandeepsingh Arora, Sravan Kumar, S. Banavali, K. Prabhash
{"title":"Clinical Profile and Outcomes of Carcinoma Penis patients receiving systemic therapy at an Indian tertiary care centre: A retrospective observational study","authors":"V. Noronha, Venkatesh Kapu, Amit Joshi, N. Menon, Ajay Singh, G. Prakash, S. Menon, N. Sable, V. Murthy, M. Pal, Amandeepsingh Arora, Sravan Kumar, S. Banavali, K. Prabhash","doi":"10.1016/j.clgc.2024.02.004","DOIUrl":"https://doi.org/10.1016/j.clgc.2024.02.004","url":null,"abstract":"","PeriodicalId":93941,"journal":{"name":"Clinical genitourinary cancer","volume":"1353 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139830965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.clgc.2024.02.003
Xin Wang, Larissa Waldman, Yael Silberman, Michael Wang, Caleb Tackey, Lilian Hanna, Danny Vesprini, Urban Emmenegger, Andrea Eisen, M. Smoragiewicz
{"title":"Mainstream model of genetic testing for prostate cancer at a large tertiary cancer centre","authors":"Xin Wang, Larissa Waldman, Yael Silberman, Michael Wang, Caleb Tackey, Lilian Hanna, Danny Vesprini, Urban Emmenegger, Andrea Eisen, M. Smoragiewicz","doi":"10.1016/j.clgc.2024.02.003","DOIUrl":"https://doi.org/10.1016/j.clgc.2024.02.003","url":null,"abstract":"","PeriodicalId":93941,"journal":{"name":"Clinical genitourinary cancer","volume":"50 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139892769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.clgc.2024.02.005
Sarah Fleming, Dina Gifkins, H. Resnick, Waleed Shalaby, Philip Rosenberg, Chris Gaj, Vittorio Maio, Albert Crawford, Grace Lu-Yao, Jianjun Gao, A. Siefker-Radtke
{"title":"Prognostic Value of Fibroblast Growth Factor Receptor Genetic Alterations in Metastatic Urothelial Carcinoma","authors":"Sarah Fleming, Dina Gifkins, H. Resnick, Waleed Shalaby, Philip Rosenberg, Chris Gaj, Vittorio Maio, Albert Crawford, Grace Lu-Yao, Jianjun Gao, A. Siefker-Radtke","doi":"10.1016/j.clgc.2024.02.005","DOIUrl":"https://doi.org/10.1016/j.clgc.2024.02.005","url":null,"abstract":"","PeriodicalId":93941,"journal":{"name":"Clinical genitourinary cancer","volume":"18 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139818629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号