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Accessory Breast Tissue 附属乳腺组织
Pub Date : 2012-04-23 DOI: 10.53347/rid-74571
Priti P. Patel, Ahmed M. S. Ibrahim, Jacob Zhang, John T. Nguyen, Samuel J. Lin, Bernard T. Lee
DESCRIPTION A 36-year-old woman presents with significant pain and swelling over the left axillary area, which she reports worsened over the last 3 years. The tenderness becomes more prominent with her menstrual cycle. The patient denies any other changes in her breast.
一位36岁的女性表现为左侧腋窝区域明显疼痛和肿胀,她报告在过去的3年里病情恶化。痛感随着月经周期的增加而加重。病人否认乳房有其他变化。
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引用次数: 31
Craniosynostosis 颅缝早闭
Pub Date : 2012-03-10 DOI: 10.32388/134048
A. Hoey, B. Carson, A. Dorafshar
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引用次数: 0
Hyperhidrosis 多汗
Pub Date : 2008-04-18 DOI: 10.1007/978-3-319-89527-7
L. P. Stolman
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引用次数: 1
Amnion-derived Cellular Cytokine Solution 羊膜衍生细胞因子溶液
Pub Date : 2008-04-07 DOI: 10.32388/o81vsv
D. Steed, C. Trumpower, D. Duffy, Charlotte A. Smith, V. Marshall, R. Rupp, M. Robson
Objective: Wound repair is a complex integration of dynamic processes mediated by humeral messages controlling the levels of cytokines, growth factors, and matrix metalloproteinases in the wound space. Isolated growth factors and growth factor combinations have been used to accelerate wound healing with limited success. A cellular cytokine solution can be collected by harvesting the proteins released from amnion-derived multipotent progenitor cells. The purpose of this study was to compare levels of cytokines/growth factors in amnion-derived cellular cytokine solution with physiological levels reported in the medical literature. Methods: Amnion-derived multipotent progenitor cells were grown to confluency, and the proteins secreted were characterized by qualitative and quantitative analysis. These results were compared with physiologic levels reported in the medical literature. Results: The results demonstrated that amnion-derived cellular cytokine solution contained physiologic levels of cytokines relevant to wound healing, including platelet-derived growth factor, vascular endothelial growth factor, angiogenin, transforming growth factor β 2, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2. The ranges (mean ± standard deviation) were as follows: platelet-derived growth factor, 86 ± 33 pg/mL; vascular endothelial growth factor, 5.7 ± 1.5 ng/mL; angiogenin, 1.0 ± 0.33 ng/mL; transforming growth factor β 2, 500 ± 330pg/mL; tissue inhibitor of metalloproteinase-1, 530 ± 140 ng/mL; and tissue inhibitor of metalloproteinase-2230 ± 40 ng/mL. These levels are comparable with the physiologic levels reported in the literature. Conclusions: The physiologic levels of cytokines important to healing found in amnion-derived cellular cytokine solution suggest that amnion-derived cellular cytokine solution may be of benefit in healing certain acute and chronic wounds.
目的:伤口修复是一个复杂的动态过程,由肱骨信息介导,控制着伤口空间中细胞因子、生长因子和基质金属蛋白酶的水平。分离生长因子和生长因子组合已被用于加速伤口愈合,但成功率有限。通过收集羊膜衍生的多能祖细胞释放的蛋白质,可以收集细胞细胞因子溶液。本研究的目的是比较羊膜源性细胞因子溶液中细胞因子/生长因子的水平与医学文献中报道的生理水平。方法:培养羊膜源性多能祖细胞,并对其分泌的蛋白进行定性和定量分析。这些结果与医学文献中报道的生理水平进行了比较。结果:羊膜源性细胞因子溶液中含有与伤口愈合相关的生理水平的细胞因子,包括血小板源性生长因子、血管内皮生长因子、血管生成素、转化生长因子β 2、金属蛋白酶-1组织抑制剂和金属蛋白酶-2组织抑制剂。范围(平均值±标准差)如下:血小板衍生生长因子,86±33 pg/mL;血管内皮生长因子,5.7±1.5 ng/mL;血管生成素,1.0±0.33 ng/mL;转化生长因子β 2500±330pg/mL;金属蛋白酶组织抑制剂1,530±140 ng/mL;金属蛋白酶组织抑制剂2230±40 ng/mL。这些水平与文献中报道的生理水平相当。结论:羊膜源性细胞因子溶液中对愈合有重要作用的细胞因子的生理水平表明羊膜源性细胞因子溶液可能有利于某些急慢性伤口的愈合。
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引用次数: 5
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Eplasty
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