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Fetal cardiac function is altered by circumvallate placenta. 胎儿心功能被环瓣胎盘改变。
Pub Date : 2024-11-29 DOI: 10.5603/gpl.101714
Oskar Sylwestrzak, Katarzyna Zych-Krekora, Lukasz Sokolowski, Maciej Ziebakowski, Michal Krekora
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引用次数: 0
Strategies to reduce cesarean deliveries: surveying polish obstetricians on external cephalic version practices. 减少剖宫产的策略:调查波兰产科医生的头外版本做法。
Pub Date : 2024-11-29 DOI: 10.5603/gpl.102550
Maisa Manasar-Dyrbus, Agnieszka Drosdzol-Cop, Szymon Stojko, Rafal Stojko, Jakub Staniczek

Objectives: The cross-sectional survey was conducted aiming to evaluate the knowledge and experiences of the Polish obstetricians and gynecologists regarding the External Cephalic Version (ECV) and investigate their practices concerning this procedure.

Material and methods: An online survey constituting author-created questionnaire with 22 questions, was distributed among gynecologists and obstetricians. The questionnaire evaluated participants' knowledge about ECV, work experiences, and workplace practices.

Results: Out of 461 respondents, 56.20% were specialists in gynecology and obstetrics. Elective cesarean section (CS) was preferred by 78.70% for primiparas and 73.50% for multiparas with non-cephalic presentation, while ECV would be chosen by 21.3% and 23.6%, respectively. While 73.80% knew centers performing ECV, only 16.70% had actively participated in the procedure. Major differences in the experiences and knowledge regarding ECV were observed based on work experience, and workplace reference level. Experienced physicians showed higher concerns about ECV complications and emergency CS risks. The most common concerns regarding the procedure referred to periprocedural pain, perceived low efficacy, and complications, and were more prevalent among respondents with longer experience and from lower-reference centers.

Conclusions: The study demonstrated that among Polish obstetricians for term pregnancies with non-cephalic presentation, elective cesarean section is preferred over ECV, especially among experienced practitioners. Knowledge about ECV was relatively low, indicating a need for improved educational efforts. Addressing concerns about ECV's safety and efficacy, particularly through enhanced training and anesthesia options, could promote its adoption and reduce CS rates.

目的:进行横断面调查,旨在评估波兰妇产科医生关于外头位版本(ECV)的知识和经验,并调查他们关于该程序的做法。材料和方法:在妇产科医生中进行了一项在线调查,包括作者制作的22个问题的问卷。问卷评估了参与者关于ECV的知识、工作经验和工作实践。结果:461名被调查者中,56.20%为妇产科专科医师。初产妇选择选择性剖宫产(CS)的比例为78.70%,多产妇选择非头位剖宫产的比例为73.50%,选择ECV的比例分别为21.3%和23.6%。73.80%的患者知道实施体外循环的中心,但只有16.70%的患者积极参与手术。根据工作经验和工作场所参考水平,观察到有关ECV的经验和知识的主要差异。经验丰富的医生对ECV并发症和急诊CS风险表现出更高的担忧。最常见的问题是围手术期疼痛、低疗效和并发症,在经验较长和来自较低参考中心的受访者中更为普遍。结论:研究表明,波兰产科医生对足月妊娠与非头位表现,选择性剖宫产优先于ECV,特别是在经验丰富的从业者。对ECV的认识相对较低,表明需要加强教育工作。解决对ECV安全性和有效性的担忧,特别是通过加强培训和麻醉选择,可以促进其采用并降低CS率。
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引用次数: 0
Cardiovascular profile score (CVPS) and selected cardiac parameters in fetuses with Vein of Galen Malformation. 盖伦静脉畸形胎儿的心血管特征评分(CVPS)和选择的心脏参数。
Pub Date : 2024-11-29 DOI: 10.5603/gpl.102062
Aleksandra Juras, Tomasz Wloch, Wojciech Cnota, Agata Wloch

Objectives: Vein of Galen Malformation (VGAM) is a rare congenital cerebrovascular anomaly. Early detection and monitoring of concurrent fetal heart failure in VGAM are crucial for improving outcomes. The study aims to evaluate heart anatomy, systolic and diastolic heart function, and indicators of heart failure in fetuses referred to a tertiary center due to VGAM detected in the second or third trimester.

Material and methods: This single-center retrospective study of echocardiographic data from five fetuses with VGAM examined between 2008 and 2023. Parameters analyzed included gestational age, reason for referral, cardiovascular profile score (CVPS), systolic and diastolic heart function and selected cardiac parameters RESULTS: Cardiomegaly as a sign of congestive heart failure was the main reason for referral most of the fetuses (4/5 - 80%) diagnosed later as VGAM in our center. Abnormal cerebral vessel flow was visualized in all cases, with normal umbilical arterial flow. Three fetuses were treated prenatally with digoxin due to congestive heart failure. Monophasic tricuspid valve inflow and decreased shortening fraction (SF) were observed in three fetuses (60%) at the time of diagnosis. CVPS scores ranged from 2 to 10, correlating with the severity of cardiac compromise. All five patients demised, three died in utero, and two shortly after birth.

Conclusions: This study emphasizes the severe cardiac implications of VGAM detected in utero and the need for early and comprehensive fetal assessment. Despite early diagnosis, outcomes remain poor, necessitating further research into effective prenatal treatments and management protocols to enhance survival for affected fetuses.

目的:盖伦静脉畸形(VGAM)是一种罕见的先天性脑血管畸形。早期发现和监测VGAM并发胎儿心力衰竭对改善预后至关重要。该研究旨在评估心脏解剖、心脏收缩和舒张功能,以及由于妊娠中期或晚期检测到VGAM而转介到三级中心的胎儿心力衰竭的指标。材料和方法:本研究对2008年至2023年间5例VGAM胎儿的超声心动图数据进行了单中心回顾性研究。分析的参数包括胎龄、转诊原因、心血管谱评分(CVPS)、心脏收缩和舒张功能以及选择的心脏参数。结果:心脏肥大作为充血性心力衰竭的标志是我中心大多数胎儿(4/5 - 80%)后来诊断为VGAM的转诊的主要原因。所有病例均见脑血管血流异常,脐动脉血流正常。由于充血性心力衰竭,三个胎儿在产前用地高辛治疗。在诊断时观察到三个胎儿(60%)单相三尖瓣流入和缩短分数(SF)下降。CVPS评分范围从2到10,与心脏损害的严重程度相关。5名患者全部死亡,其中3名在子宫内死亡,2名在出生后不久死亡。结论:本研究强调了子宫内检测到的VGAM对心脏的严重影响以及早期和全面的胎儿评估的必要性。尽管早期诊断,结果仍然很差,需要进一步研究有效的产前治疗和管理方案,以提高影响胎儿的存活率。
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引用次数: 0
ADAM 12 as a prognostic factor of pregnancy induced hypertension - preliminary study. adam12作为妊娠高血压预后因素的初步研究。
Pub Date : 2024-11-29 DOI: 10.5603/gpl.102668
Katarzyna Zych-Krekora, Oskar Sylwestrzak, Milena Skibinska, Maciej Ziebakowski, Michal Krekora
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引用次数: 0
FIGO 2023 - too soon or just in time? Evolution or a revolution? Review of the newest endometrial cancer staging classification. 2023年菲戈:太早还是刚刚好?进化还是革命?最新子宫内膜癌分期分类综述。
Pub Date : 2024-11-29 DOI: 10.5603/gpl.102620
Marcin Misiek, Agnieszka Picheta, Kaja Michalczyk, Tomasz Kluz, Tomasz Kluz, Andrzej Wrobel, Rafal Stojko, Anita Chudecka-Glaz

The FIGO staging system is an integral part of the therapeutic and treatment process in female genital tumors. It cements the knowledge gained to date to plan patient treatment prognosis and the course of the disease and compare treatment outcomes between centers in the most individualized yet systematic way. In response to these assumptions, the FIGO Committee on Gynaecological Oncology updated the endometrial cancer staging classification in June 2023. The new endometrial cancer staging classification includes multiple clinicopathological prognostic factors and molecular findings for the first time. In this review, we summarize the differences between the new and the old FIGO classification and comment on its everyday real-world application.

FIGO分期系统是女性生殖器肿瘤治疗和治疗过程中不可或缺的一部分。它巩固了迄今为止获得的知识,以计划患者治疗预后和病程,并以最个性化但系统的方式比较中心之间的治疗结果。根据这些假设,FIGO妇科肿瘤委员会于2023年6月更新了子宫内膜癌分期分类。新的子宫内膜癌分期分类首次包括多种临床病理预后因素和分子发现。在这篇综述中,我们总结了新旧FIGO分类之间的差异,并对其日常实际应用进行了评论。
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引用次数: 0
Clinical application of Synthetic Osmotic Cervical Dilator in labor pre-induction: departmental protocol and literature review. 人工合成渗透性宫颈扩张器在引产前的临床应用:部门规程和文献综述。
Pub Date : 2024-11-08 DOI: 10.5603/gpl.100984
Maisa Mansar-Dyrbus, Katarzyna Wilk, Maja Zieba-Domalik, Jakub Staniczek, Rafal Stojko
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引用次数: 0
Breastfeeding myths - the prevalence among the population of Polish women. 母乳喂养误区--波兰妇女中的普遍现象。
Pub Date : 2024-11-08 DOI: 10.5603/gpl.95496
Zuzanna Tomczewska, Aleksandra Jaron, Joanna Kacperczyk-Bartnik, Agnieszka Dobrowolska-Redo, Ewa Romejko-Wolniewicz

Objectives: Exclusive breastfeeding is recommended until the child is six months of age. However, there are many myths about breastfeeding. The aim of our study was to assess the knowledge of Polish women about breastfeeding.

Material and methods: A cross-sectional survey study was conducted among 1536 Polish women. A self-administered questionnaire was created using Google Forms survey management software and distributed online. The participants were asked about the most common myths in society regarding breastfeeding.

Results: The highest number of correct answers in all age groups were given to questions related to the nutritional value of breast milk (80.9-94.9%). The fewest correct answers in each age group were recorded to questions concerning the possibility of getting pregnant during the first 6 months of breastfeeding (16.1-35.3%), the safety of drinking non-alcoholic beer during lactation (24.4-37.1%), the benefits of brushing the breast while breastfeeding (16.0-37.1%), and the effectiveness of compresses made of cabbage leaves or sage infusions in relieving ailments during milk rush (6.8-12.4%). Higher education and being a mother were associated with a higher number of correct answers. Age below 25 years was associated with lower number of correct answers.

Conclusions: The results of the survey regarding breastfeeding suggest the existence of various beliefs in the population of Polish women which are not evidence based. This indicates the need for spreading adequate information about breastfeeding, especially among younger women and those who did not obtain higher education.

目的:建议纯母乳喂养至婴儿六个月大。然而,关于母乳喂养却存在许多误解。我们的研究旨在评估波兰妇女对母乳喂养的认识:我们对 1536 名波兰妇女进行了横断面调查研究。我们使用 Google Forms 调查管理软件制作了一份自填式问卷,并在网上分发。调查对象被问及社会上最常见的母乳喂养误区:在所有年龄组中,母乳营养价值相关问题的正确答案数最多(80.9%-94.9%)。各年龄组中回答正确率最低的问题分别是:母乳喂养前 6 个月怀孕的可能性(16.1%-35.3%)、哺乳期饮用无酒精啤酒的安全性(24.4%-37.1%)、哺乳期刷洗乳房的好处(16.0%-37.1%)以及用卷心菜叶或鼠尾草泡水敷面对缓解挤奶期不适的效果(6.8%-12.4%)。教育程度较高和身为母亲的人回答正确率较高。结论:有关母乳喂养的调查结果表明,波兰妇女群体中存在着各种缺乏证据的观念。这表明有必要传播有关母乳喂养的充分信息,尤其是在年轻女性和未受过高等教育的女性中。
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引用次数: 0
Comparison of the efficacy and safety of dinoprostone and double-balloon catheters in cervical ripening: a propensity score matching retrospective study. 比较地诺前列酮和双气囊导管在宫颈成熟术中的有效性和安全性:倾向评分匹配回顾性研究。
Pub Date : 2024-11-08 DOI: 10.5603/gpl.101957
Chun Yang, Liulan Qian, Qiucheng Jia, Hao Mao

Objectives: The methods of prompting cervical ripening (CR) include mechanical and pharmacological approaches. The former seems safer. However, this superiority may change with the application of a new labor curve. Therefore, we aimed to compare the efficacy and safety of dinoprostone and double-balloon catheters (DBC) in promoting CR in induction of labor (IOL).

Material and methods: A total of 877 primipara women with Bishop score ≤ 6 were divided into the dinoprostone group (n = 502) and DBC group (n = 375) according to the IOL way. The women in the dinoprostone group received dinoprostone to perform IOL, while those in the DBC group received DBC to perform IOL. The natural birth rate, time to labor onset and birth, and maternal and neonatal complications were compared between the two groups. A propensity score match (PSM) was used to eliminate the selection bias.

Results: A total of 516 cases were left after PSM (1:1) to Bishop score. The dinoprostone was associated with an improved Bishop score. However, there were no significant differences in the vaginal delivery rate, the stage of labor, and the time from ripening to labor onset and delivery between the two groups (p > 0.05). The incidence rates of puerperal infection and blood loss were notably higher in the DBC group than in the dinoprostone group (p < 0.05). However, there was no statistical difference in the incidence of postpartum hemorrhage between the two groups (p > 0.05).

Conclusions: Dinoprostone is associated with a lower puerperal infection rate and improved Bishop score in IOL without an increased success rate of vaginal delivery.

目的:促使宫颈成熟(CR)的方法包括机械法和药物法。前者似乎更安全。然而,这种优越性可能会随着新的分娩曲线的应用而改变。因此,我们旨在比较地诺前列酮和双气囊导管(DBC)在促进引产(IOL)中宫颈成熟的有效性和安全性:根据IOL方式将Bishop评分≤6分的877名初产妇分为地诺前列酮组(502人)和DBC组(375人)。地诺前列酮组产妇接受地诺前列酮进行 IOL,而 DBC 组产妇接受 DBC 进行 IOL。对两组产妇的自然分娩率、临产和分娩时间、产妇和新生儿并发症进行了比较。采用倾向得分匹配法(PSM)消除选择偏差:结果:经过倾向评分匹配(1:1)后,共有 516 个病例与 Bishop 评分相符。地诺前列酮与 Bishop 评分的提高有关。然而,两组产妇的阴道分娩率、产程以及从成熟到分娩开始和分娩的时间均无明显差异(P > 0.05)。DBC 组的产褥感染和失血发生率明显高于地诺前列酮组(P < 0.05)。然而,两组产后出血的发生率没有统计学差异(P > 0.05):结论:地诺前列酮可降低产褥感染率,提高 IOL 的 Bishop 评分,但不会增加阴道分娩的成功率。
{"title":"Comparison of the efficacy and safety of dinoprostone and double-balloon catheters in cervical ripening: a propensity score matching retrospective study.","authors":"Chun Yang, Liulan Qian, Qiucheng Jia, Hao Mao","doi":"10.5603/gpl.101957","DOIUrl":"https://doi.org/10.5603/gpl.101957","url":null,"abstract":"<p><strong>Objectives: </strong>The methods of prompting cervical ripening (CR) include mechanical and pharmacological approaches. The former seems safer. However, this superiority may change with the application of a new labor curve. Therefore, we aimed to compare the efficacy and safety of dinoprostone and double-balloon catheters (DBC) in promoting CR in induction of labor (IOL).</p><p><strong>Material and methods: </strong>A total of 877 primipara women with Bishop score ≤ 6 were divided into the dinoprostone group (n = 502) and DBC group (n = 375) according to the IOL way. The women in the dinoprostone group received dinoprostone to perform IOL, while those in the DBC group received DBC to perform IOL. The natural birth rate, time to labor onset and birth, and maternal and neonatal complications were compared between the two groups. A propensity score match (PSM) was used to eliminate the selection bias.</p><p><strong>Results: </strong>A total of 516 cases were left after PSM (1:1) to Bishop score. The dinoprostone was associated with an improved Bishop score. However, there were no significant differences in the vaginal delivery rate, the stage of labor, and the time from ripening to labor onset and delivery between the two groups (p > 0.05). The incidence rates of puerperal infection and blood loss were notably higher in the DBC group than in the dinoprostone group (p < 0.05). However, there was no statistical difference in the incidence of postpartum hemorrhage between the two groups (p > 0.05).</p><p><strong>Conclusions: </strong>Dinoprostone is associated with a lower puerperal infection rate and improved Bishop score in IOL without an increased success rate of vaginal delivery.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of a patient at reproductive age with BRCA2 and CHEK2 mutations and multiple uterine fibroids. 一例育龄患者,BRCA2 和 CHEK2 基因突变,多发性子宫肌瘤。
Pub Date : 2024-11-08 DOI: 10.5603/gpl.95221
Artur Skowyra, Lidia Korczynska, Jakub Kociuba, Sylwia Szczesniewska, Michal Ciebiera
{"title":"A case of a patient at reproductive age with BRCA2 and CHEK2 mutations and multiple uterine fibroids.","authors":"Artur Skowyra, Lidia Korczynska, Jakub Kociuba, Sylwia Szczesniewska, Michal Ciebiera","doi":"10.5603/gpl.95221","DOIUrl":"https://doi.org/10.5603/gpl.95221","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations vulvar lichen sclerosus with autoimmune thyroid diseases. 外阴硬皮病与自身免疫性甲状腺疾病的关系
Pub Date : 2024-10-29 DOI: 10.5603/gpl.103145
Maja J Zieba-Domalik, Dominika Orszulak, Kacper Nizinski, Katarzyna Wilk, Marta Janik, Rafal Stojko, Agnieszka Drosdzol-Cop

Objectives: Vulvar lichen sclerosus (VLS) is defined as a chronic inflammatory skin disease that most often involves lesions on the mucous membranes of the vulva with a tendency to progress to the anal skin. The etiopathogenesis of VLS remains unknown and is likely multifactorial. Data emphasize the role of immunological factors - more than 25% of VLS cases coexist with autoimmune diseases. The purpose of the present study was to determine the correlation of the prevalence of anti-thyroid antibodies - IgG class antibodies against thyroid peroxidase and IgG class antibodies against thyroglobulin in women with vulvar lichen sclerosus, and the appropriateness of screening tests for autoimmune thyroid diseases in women with vulvar lichen sclerosus.

Material and methods: Fifty women with vulvar lichen sclerosus were enrolled in the study. The control group consisted of 41 healthy women. A detailed medical history was taken with all patients, followed by laboratory determinations - anti-thyroid antibodies - IgG class antibodies against thyroid peroxidase and IgG class antibodies against thyroglobulin.

Results: Antibodies to thyroid peroxidase were present in 12% of the study group with vulvar lichen sclerosus and 4.88% of the control group, and this difference was not statistically significant (p = 0.41). Anti-thyroglobulin antibodies were detected in 4% of the patients with vulvar lichen sclerosus and 4.88% of the control group, and this difference was not statistically significant either (p = 0.76).

Conclusions: The study did not confirm the association of VLS with autoimmune thyroid diseases. Undoubtedly, based on the data available in the literature, further studies are needed to determine the mechanisms behind the association between vulvar lichen sclerosus and autoimmune thyroid diseases.

目的:外阴硬化性苔藓(VLS)是一种慢性炎症性皮肤病,多发于外阴粘膜,并有向肛门皮肤发展的趋势。VLS 的发病机制尚不清楚,可能是多因素引起的。有数据强调了免疫因素的作用--超过 25% 的 VLS 病例与自身免疫性疾病同时存在。本研究的目的是确定外阴硬化性苔藓妇女中抗甲状腺抗体(抗甲状腺过氧化物酶IgG类抗体和抗甲状腺球蛋白IgG类抗体)患病率的相关性,以及外阴硬化性苔藓妇女自身免疫性甲状腺疾病筛查试验的适宜性:研究对象为50名患有外阴硬化性苔藓的妇女。对照组由 41 名健康妇女组成。向所有患者详细询问病史,然后进行实验室测定--抗甲状腺抗体--甲状腺过氧化物酶 IgG 类抗体和甲状腺球蛋白 IgG 类抗体:甲状腺过氧化物酶抗体在外阴硬皮病研究组中占 12%,在对照组中占 4.88%,差异无统计学意义(P = 0.41)。4%的外阴硬化性苔藓患者和4.88%的对照组患者检测到抗甲状腺球蛋白抗体,差异也无统计学意义(P = 0.76):该研究并未证实外阴硬化症与自身免疫性甲状腺疾病有关。毫无疑问,根据现有的文献数据,还需要进一步的研究来确定外阴苔藓硬化症与自身免疫性甲状腺疾病之间的关联机制。
{"title":"Associations vulvar lichen sclerosus with autoimmune thyroid diseases.","authors":"Maja J Zieba-Domalik, Dominika Orszulak, Kacper Nizinski, Katarzyna Wilk, Marta Janik, Rafal Stojko, Agnieszka Drosdzol-Cop","doi":"10.5603/gpl.103145","DOIUrl":"https://doi.org/10.5603/gpl.103145","url":null,"abstract":"<p><strong>Objectives: </strong>Vulvar lichen sclerosus (VLS) is defined as a chronic inflammatory skin disease that most often involves lesions on the mucous membranes of the vulva with a tendency to progress to the anal skin. The etiopathogenesis of VLS remains unknown and is likely multifactorial. Data emphasize the role of immunological factors - more than 25% of VLS cases coexist with autoimmune diseases. The purpose of the present study was to determine the correlation of the prevalence of anti-thyroid antibodies - IgG class antibodies against thyroid peroxidase and IgG class antibodies against thyroglobulin in women with vulvar lichen sclerosus, and the appropriateness of screening tests for autoimmune thyroid diseases in women with vulvar lichen sclerosus.</p><p><strong>Material and methods: </strong>Fifty women with vulvar lichen sclerosus were enrolled in the study. The control group consisted of 41 healthy women. A detailed medical history was taken with all patients, followed by laboratory determinations - anti-thyroid antibodies - IgG class antibodies against thyroid peroxidase and IgG class antibodies against thyroglobulin.</p><p><strong>Results: </strong>Antibodies to thyroid peroxidase were present in 12% of the study group with vulvar lichen sclerosus and 4.88% of the control group, and this difference was not statistically significant (p = 0.41). Anti-thyroglobulin antibodies were detected in 4% of the patients with vulvar lichen sclerosus and 4.88% of the control group, and this difference was not statistically significant either (p = 0.76).</p><p><strong>Conclusions: </strong>The study did not confirm the association of VLS with autoimmune thyroid diseases. Undoubtedly, based on the data available in the literature, further studies are needed to determine the mechanisms behind the association between vulvar lichen sclerosus and autoimmune thyroid diseases.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Ginekologia polska
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