This survey was performed in order to investigate the incidence of adverse reactions to radiopharmaceuticals in FY2024 in Japan. It was based on responses to questionnaires sent to nuclear medicine institutions. Replies were obtained from 989 institutions out of 1,176 to which the questionnaire had been sent. A total of 925,315 radiopharmaceutical administrations were reported. Nine cases of adverse reactions were reported. The incidence of adverse reactions per 100,000 cases was 1.0. No case of defective products was reported.
{"title":"[The 47th Report on Survey of the Adverse Reaction to Radiopharmaceuticals (The 50th Survey in 2024)].","authors":"Hidehiko Okazawa, Tomoya Uehara, Daiki Kayano, Ichiei Kuji, Tatsuya Higashi, Mana Yoshimura","doi":"10.18893/kakuigaku.rp.2631","DOIUrl":"https://doi.org/10.18893/kakuigaku.rp.2631","url":null,"abstract":"<p><p>This survey was performed in order to investigate the incidence of adverse reactions to radiopharmaceuticals in FY2024 in Japan. It was based on responses to questionnaires sent to nuclear medicine institutions. Replies were obtained from 989 institutions out of 1,176 to which the questionnaire had been sent. A total of 925,315 radiopharmaceutical administrations were reported. Nine cases of adverse reactions were reported. The incidence of adverse reactions per 100,000 cases was 1.0. No case of defective products was reported.</p>","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"63 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146121531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: Radionuclide therapy often involve long waiting periods due to limited numbers of radioisotope therapy rooms and special measures rooms, and strict regulations. The purpose of this study was to estimate the waiting period for radionuclide therapy, considering the increased utilization of nuclear medicine and greater demand due to new drugs. The study also examined possible factors that may limit the treatment provision system and investigate appropriate treatment environments that could shorten the waiting period.
Method: We developed a discrete event simulation, using three prefectures as a model, to predict the number of patients with a long waiting period and determine the effectiveness of environmental measures designed to shorten the waiting period. The model took considered the demand for radionuclide therapy and medical resources, such as the number of treatment beds, as input values.
Results: The simulation predicted that, within 4 years after the introduction of [177Lu]Lu-PSMA-617, the number of patients waiting >180 days for treatment would increase significantly in all three prefectures. The limited number of beds was the leading cause of the long waiting period. However, just increasing the number of beds was ineffective for reducing the waiting period in some facilities due to regulatory factors, and measures to improve the drainage capacity were also necessary.
Conclusion: The number of patients with a long waiting period is expected to increase significantly due to the rapid increase in demand for radionuclide therapy. A combination of measures, including increasing the number of beds, improving drainage capacity, and better utilization of available medical resources through interfacility cooperation, are factors that need urgent attention to reduce the waiting time for radionuclide therapy.
{"title":"[Evaluation of Appropriate Treatment Infrastructure for Radionuclide Therapy Through Discrete Event Simulation].","authors":"Takashi Mizowaki, Makoto Hosono, Hiroji Uemura, Masatoshi Eto, Mototsugu Oya, Hideaki Miyake, Masafumi Ikeda, Ayako Kanegasaki, Shunsuke Sakuragi, Yuhei Oida, Seigo Kinuya","doi":"10.18893/kakuigaku.oa.2503","DOIUrl":"https://doi.org/10.18893/kakuigaku.oa.2503","url":null,"abstract":"<p><strong>Purpose: </strong>Radionuclide therapy often involve long waiting periods due to limited numbers of radioisotope therapy rooms and special measures rooms, and strict regulations. The purpose of this study was to estimate the waiting period for radionuclide therapy, considering the increased utilization of nuclear medicine and greater demand due to new drugs. The study also examined possible factors that may limit the treatment provision system and investigate appropriate treatment environments that could shorten the waiting period.</p><p><strong>Method: </strong>We developed a discrete event simulation, using three prefectures as a model, to predict the number of patients with a long waiting period and determine the effectiveness of environmental measures designed to shorten the waiting period. The model took considered the demand for radionuclide therapy and medical resources, such as the number of treatment beds, as input values.</p><p><strong>Results: </strong>The simulation predicted that, within 4 years after the introduction of [<sup>177</sup>Lu]Lu-PSMA-617, the number of patients waiting >180 days for treatment would increase significantly in all three prefectures. The limited number of beds was the leading cause of the long waiting period. However, just increasing the number of beds was ineffective for reducing the waiting period in some facilities due to regulatory factors, and measures to improve the drainage capacity were also necessary.</p><p><strong>Conclusion: </strong>The number of patients with a long waiting period is expected to increase significantly due to the rapid increase in demand for radionuclide therapy. A combination of measures, including increasing the number of beds, improving drainage capacity, and better utilization of available medical resources through interfacility cooperation, are factors that need urgent attention to reduce the waiting time for radionuclide therapy.</p>","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 1","pages":"59-70"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144983740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This survey was performed in order to investigate the incidence of adverse reactions to radiopharmaceuticals in FY2023 in Japan. It was based on responses to questionnaires sent to nuclear medicine institutions. Replies were obtained from 971 institutions out of 1,181 to which the questionnaire had been sent. A total of 884,272 radiopharmaceutical administrations were reported. Fifteen cases of adverse reactions were reported. The incidence of adverse reactions per 100,000 cases was 1.7. No case of defective products was reported.
{"title":"[The 46th Report on Survey of the Adverse Reaction to Radiopharmaceuticals (The 49th Survey in 2023)].","authors":"Hidehiko Okazawa, Tomoya Uehara, Daiki Kayano, Ichiei Kuji, Tatsuya Higashi, Mana Yoshimura","doi":"10.18893/kakuigaku.rp.2531","DOIUrl":"10.18893/kakuigaku.rp.2531","url":null,"abstract":"<p><p>This survey was performed in order to investigate the incidence of adverse reactions to radiopharmaceuticals in FY2023 in Japan. It was based on responses to questionnaires sent to nuclear medicine institutions. Replies were obtained from 971 institutions out of 1,181 to which the questionnaire had been sent. A total of 884,272 radiopharmaceutical administrations were reported. Fifteen cases of adverse reactions were reported. The incidence of adverse reactions per 100,000 cases was 1.7. No case of defective products was reported.</p>","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 1","pages":"7-17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.18893/kakuigaku.62.S99
{"title":"[Special Program Abstracts].","authors":"","doi":"10.18893/kakuigaku.62.S99","DOIUrl":"https://doi.org/10.18893/kakuigaku.62.S99","url":null,"abstract":"","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 Supplement","pages":"S99-S226"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.18893/kakuigaku.arm.2535
{"title":"","authors":"","doi":"10.18893/kakuigaku.arm.2535","DOIUrl":"https://doi.org/10.18893/kakuigaku.arm.2535","url":null,"abstract":"","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 1","pages":"45-46"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.18893/kakuigaku.rgr.2532
{"title":"","authors":"","doi":"10.18893/kakuigaku.rgr.2532","DOIUrl":"https://doi.org/10.18893/kakuigaku.rgr.2532","url":null,"abstract":"","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 1","pages":"19-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.18893/kakuigaku.arm.2534
{"title":"","authors":"","doi":"10.18893/kakuigaku.arm.2534","DOIUrl":"https://doi.org/10.18893/kakuigaku.arm.2534","url":null,"abstract":"","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 1","pages":"39-43"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144510118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.18893/kakuigaku.arm.2533
{"title":"","authors":"","doi":"10.18893/kakuigaku.arm.2533","DOIUrl":"https://doi.org/10.18893/kakuigaku.arm.2533","url":null,"abstract":"","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 1","pages":"33-38"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.18893/kakuigaku.62.A6
{"title":"","authors":"","doi":"10.18893/kakuigaku.62.A6","DOIUrl":"https://doi.org/10.18893/kakuigaku.62.A6","url":null,"abstract":"","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 Supplement","pages":"A6"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145454437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.18893/kakuigaku.62.A1
{"title":"","authors":"","doi":"10.18893/kakuigaku.62.A1","DOIUrl":"https://doi.org/10.18893/kakuigaku.62.A1","url":null,"abstract":"","PeriodicalId":94120,"journal":{"name":"Kaku igaku. The Japanese journal of nuclear medicine","volume":"62 Supplement","pages":"A1-A2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145454458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号