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Influence of learning effect on reliability parameters and global indices of standard automated perimetry in cases of primary open angle glaucoma. 学习效果对原发性开角型青光眼患者标准自动视野的可靠性参数和总体指标的影响。
Pub Date : 2018-10-01
Uma Sharan Tiwari, Ankita Aishwarya, Akanksha Bhale

Aim. To find out the influence of learning effect on various reliability parameters and global indices of standard automated perimetry in cases of primary open angle glaucoma. Method. Thirty eyes of 30 patients of Primary Open Angle Glaucoma constituted material for this prospective observational study. All the patients underwent standard automated perimetry three times on three different days within one week on G program of Octopus Visual Field Analyzer. The details of reliability indices, global indices, and test duration were compiled and analyzed. Result. A male preponderance was observed with a mean age of 53.43 years. The mean false positive was found to be 11.13, 6.07, and 2.40 on visit 1, visit 2, and visit 3, respectively. The mean false negative was found to be 13.73, 9.33, and 6.30 on visit 1, visit 2, and visit 3, respectively. The mean fixation loss was found to be 7.53, 3.83, and 1.60 on visit 1, visit 2, and visit 3, respectively. The mean deviation was found to be -10.14, -5.75, and -3.11 on visit 1, visit 2, and visit 3, respectively. The pattern standard deviation was found to be 5.58, 4.63, and 4.35 on visit 1, visit 2, and visit 3, respectively. The mean test duration was found to be 7.68, 6.21, & 5.51 minutes for visit 1, visit 2 and visit 3, respectively. All the values were statistically highly significant except for the pattern standard deviation. Conclusion. At least three standard automated perimetry tests should be performed for all glaucoma patients in order to obtain a base line perimetry chart.

目标了解学习效应对原发性开角型青光眼患者标准自动视野的各种可靠性参数和总体指标的影响。方法30例原发性开角型青光眼患者的30只眼睛构成了这项前瞻性观察性研究的材料。所有患者在一周内的三天内使用Octopus视野分析仪的G程序进行三次标准自动视野测量。对可靠性指标、全局指标和测试持续时间的详细信息进行了汇编和分析。后果男性占优势,平均年龄53.43岁。访视1、访视2和访视3的平均假阳性分别为11.13、6.07和2.40。访视1、访视2和访视3的平均假阴性分别为13.73、9.33和6.30。访视1、访视2和访视3的平均固定损失分别为7.53、3.83和1.60。访视1、访视2和访视3的平均偏差分别为-10.14、-5.75和-3.11。访视1、访视2和访视3的模式标准差分别为5.58、4.63和4.35。访视1、访视2和访视3的平均测试持续时间分别为7.68、6.21和5.51分钟。除模式标准差外,所有值均具有统计学高度显著性。结论所有青光眼患者应至少进行三次标准的自动视野检查,以获得基线视野图。
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引用次数: 0
Romanian ophthalmologists in the renowned ophthalmic journals worldwide. 罗马尼亚眼科医生发表在世界著名眼科杂志上。
Pub Date : 2018-10-01
Dan Călugăru, Mihai Călugăru

The authors are discussing over 80 articles that they have published in the last 5 years in the renowned ophthalmic journals worldwide, which have approached, for the first time in the ophthalmic literature, the following 4 topics: the acute central/ hemicentral retinal vein occlusion, the therapeutic interventions in the fellow eye of patients with unilateral malignant glaucoma, the persistent diabetic macular edema, and the current researches in patients with neovascular age-related macular degeneration.

作者正在讨论他们在过去5年中在世界著名眼科杂志上发表的80多篇文章,这些文章在眼科文献中首次涉及以下4个主题:急性中央/半中央视网膜静脉阻塞、单侧恶性青光眼患者对同眼的治疗干预、,持续性糖尿病黄斑水肿,以及新生血管性年龄相关性黄斑变性患者的最新研究。
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引用次数: 0
A marketing perspective on consumer perceived competition in private ophthalmology services. 私人眼科服务中消费者感知竞争的营销视角。
Pub Date : 2018-04-01
Consuela-Mădălina Gheorghe, Victor Lorin Purcărea, Iuliana-Raluca Gheorghe

Competition in health care services has been considered as a core component in the consumer value mechanism. In Romania, the emergence of private ophthalmology services has as outcome a positive-sum competition which focuses on prevention, diagnosis and treatment of eye related diseases and disorders and improved value. The purpose of this paper was to provide an insight into the knowledge used by consumers when they make a decision regarding a private ophthalmology service with a specific interest on competition. A research model was elaborated and included quality, price, and satisfaction as components influenced by competition from the consumers' perspectives. The model was validated using Structural Equation Modeling in SmartPLS. The sample was made up of 120 respondents and the sampling technique was quota. The structural model revealed that competition has a positive impact on satisfaction and explained 74% of its variance and also that competition has a positive impact on price and explained 7% of the variance. Moreover, using IPMA matrix analysis, the most powerful item of competition construct with an influence on satisfaction was the one related to the reputation of the private ophthalmology organization. Nonetheless, the key to gain competitive advantage stands in providing meaningful value to consumers using differentiation features such as high prices, reputation, and awareness on the services offered, greater availability, and the most important feature, innovation.

医疗保健服务的竞争被认为是消费者价值机制的核心组成部分。在罗马尼亚,私人眼科服务的出现带来了一场正和竞争,其重点是预防、诊断和治疗与眼睛相关的疾病和障碍,并提高了价值。本文的目的是深入了解消费者在对竞争有特殊兴趣的私人眼科服务做出决定时所使用的知识。阐述了一个研究模型,并从消费者的角度将质量、价格和满意度作为受竞争影响的组成部分。使用SmartPLS中的结构方程建模对该模型进行了验证。样本由120名受访者组成,抽样技术为配额制。结构模型显示,竞争对满意度有积极影响,并解释了74%的方差,竞争对价格有积极影响并解释了7%的方差。此外,使用IPMA矩阵分析,对满意度有影响的竞争结构中最有力的项目是与私营眼科组织声誉相关的项目。尽管如此,获得竞争优势的关键在于利用差异化特征为消费者提供有意义的价值,如高价格、声誉和对所提供服务的认识、更高的可用性,以及最重要的特征创新。
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引用次数: 0
NONICHEMIC CENTRAL RETINAL VEIN OCCLUSION ASSOCIATED WITH HEREDITARY THROMBOPHYLIA. 与遗传性血栓形成有关的非缺血性视网膜中央静脉闭塞。
Pub Date : 2015-07-01
Andreea Dana Fişuş, Doina Suzana Pop, Monica Blanka Rusu, Florina Vultur, Karin Ursula Horvath

Retinal vein occlusion (RVO) is the second most common retinal vein disease with significant visual loss via thrombus or compression of vein wall. Thrombophilia is the predisposition to vascular thrombosis with the existence of genetic defect that leads to blood hypercoagulability. This report describes the case of a 55 year old male patient, with an active life who presented himself at the emergency room with acute visual lose, insidious and progressive visual field constriction, without any known history of neurological or vascular diseases. The examinations revealed unilateral optic nerve head edema, the fluorescein angiography was specific for nonischemic central retinal vein occlusion CRVO complicated with macular edema. Blood examinations has emphasized the presence of the heterozygous mutation A1298C in the methylenetetrahydrofolate reductase gene (MTHFR), the only one presented from the thrombophilia screen panel and a slightly elevated cholesterol level. During the follow-up period, the patient received anti-VEGF treatment (Bevacizumab, 3x 0.1 ml intravitreal injections) with improved visual acuity and amendment of macular edema. The complex etiology calls for interdisciplinary approach to determine better the cause of this ophthalmological disease. Although studies have found a correlation between some thrombophilia mutations and retinal vein occlusion, more studies that contain a larger number of patients are necessary in order to determine the final role of these gene variants.

视网膜静脉闭塞(RVO)是第二大最常见的视网膜静脉疾病,会因血栓或静脉壁受压而导致视力严重下降。血栓性疾病是指存在导致血液高凝状态的遗传缺陷,易导致血管血栓形成。本报告描述了一例 55 岁男性患者的病例,该患者生性活泼好动,因急性视力丧失、隐匿性和进行性视野缩小而到急诊就诊,无任何已知的神经或血管疾病史。检查发现单侧视神经头水肿,荧光素血管造影明确为非缺血性视网膜中央静脉闭塞(CRVO)并发黄斑水肿。血液检查显示,患者存在亚甲基四氢叶酸还原酶(MTHFR)基因 A1298C 杂合突变,这是血栓性疾病筛查中唯一出现的突变,而且胆固醇水平略有升高。在随访期间,患者接受了抗血管内皮生长因子治疗(贝伐单抗,3 次 0.1 毫升玻璃体内注射),视力有所改善,黄斑水肿也有所减轻。由于病因复杂,需要采用跨学科方法来更好地确定这种眼科疾病的病因。尽管有研究发现,某些血栓性疾病基因突变与视网膜静脉闭塞之间存在相关性,但要确定这些基因变异的最终作用,还需要进行更多包含更多患者的研究。
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引用次数: 0
SELECTIVE LASER TRABECULOPLASTY--SHORT TERM EFFICACY AND SAFETY PROFILE IN OPEN ANGLE GLAUCOMA OR OCULAR HYPERTENSION TREATMENT. 选择性激光小梁成形术--开角型青光眼或眼压过高治疗的短期疗效和安全性分析。
Pub Date : 2015-07-01
Dorin Chiselita, Alina Cantemir, Anca Delia Pantalon

Unlabelled: Selective laser trabeculoplasty--medium term efficacy and safety profile in open anlgle glaucoma or ocular hypertension treatment: SLT effect in reducing the intraocular pressure (IOP) in patients with open angle glaucoma or ocular hypertension.

Material and method: 70 eyes from 70 patients were included in the study in 2014 (12 months); the established design for this research was prospective and interventional. Patients received indication for SLT treatment as initial procedure or as adjuvant method in reducing the intraocular pressure when insufficient control with topical medication was noted. A single laser procedure was performed on 360 degrees. The result was verified and compared with baseline values of IOP at 1 month, 3 months respectively.

Results: IOP decreased at 1 month with 22.47% vs. baseline IOP and with 26.58% at 3 months. The IOP dynamics showed an additional 5.30% decrease between the intermediate and final values, with statistical significance for all the measured parameters (p = 0.001).

Conclusion: SLT applied on 360 degrees in a single session represents a safe and efficient procedure. The IOP decrease is marked at 1 month, but the effect continues until later, at 3 months interval after treatment. The higher the initial IOP was, the greater effect SLT has in decreasing the IOP level. Most frequently LST helps control the IOP, but rarely allows reducing or eliminating the glaucoma medication.

无标签:选择性激光小梁成形术--开角型青光眼或高眼压症治疗的中期疗效和安全性分析:材料和方法:本研究的既定设计是前瞻性和干预性的。患者均有接受SLT治疗的指征,SLT可作为初始治疗方法,也可作为辅助方法,在局部用药无法控制眼压的情况下降低眼压。对患者进行 360 度单次激光治疗。结果显示,1 个月和 3 个月后,眼压分别下降了 22%和 22%:结果:1 个月后的眼压与基线值相比下降了 22.47%,3 个月后下降了 26.58%。眼压动态变化显示,中间值和最终值之间又下降了 5.30%,所有测量参数均有统计学意义(p = 0.001):结论:360 度单次激光治疗是一种安全高效的治疗方法。治疗 1 个月后,眼压明显下降,但效果要持续到治疗后 3 个月。最初的眼压越高,SLT 对降低眼压水平的作用就越大。大多数情况下,LST 有助于控制眼压,但很少能减少或消除青光眼药物。
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引用次数: 0
NOVELTIES IN MEDICAL TREATMENT OF GLAUCOMA. 青光眼医疗新技术。
Pub Date : 2015-04-01
Stefan Cornel, Timaru Cristina Mihaela, Iliescu Daniela Adriana, Batras Mehdi, De Simone Algerino

The purpose of this study is to review the current medical treatment and the new and better alternatives for patients with glaucoma. Glaucoma refers to a group of related eye disorders that have in common an optic neuropathy associated with visual function loss. It is one of the leading causes of irreversible blindness worldwide. Glaucoma can damage vision gradually so it may not be noticed until the disease is at an advanced stage. Early diagnosis and treatment can minimize or prevent optic nerve damage and limit glaucoma-related vision loss. Nowadays, research continues for the improvement of current medical treatment.

本研究的目的是回顾青光眼患者的现有医疗方法和新的更好的替代方法。青光眼是指一组相关的眼部疾病,其共同点是视神经病变导致视觉功能丧失。青光眼是导致全球不可逆失明的主要原因之一。青光眼会逐渐损害视力,因此可能要到晚期才会被发现。早期诊断和治疗可以最大限度地减少或预防视神经损伤,限制与青光眼相关的视力丧失。目前,有关改进现有医疗方法的研究仍在继续。
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引用次数: 0
ICE SYNDROME--CASE REPORT. 冰综合征——病例报告。
Pub Date : 2015-04-01
Valeria Coviltir, Dinu Valentin

Iridocorneal endothelial (ICE) syndrome encompasses a group of rare ocular pathologies with unilateral involvement, frequently affecting young women. The disease complex includes essential iris atrophy, Chandler's syndrome, and Cogan-Reese syndrome. In the following article, we present a case of Iridocorneal endothelial syndrome in which a late diagnosis was made and who underwent surgery for advanced glaucoma.

虹膜角膜内皮(ICE)综合征包括一组罕见的眼部病变与单侧受累,经常影响年轻女性。这种疾病包括原发性虹膜萎缩、钱德勒综合征和科根-里斯综合征。在接下来的文章中,我们提出一个虹膜角膜内皮综合征的病例,该病例被诊断为晚期青光眼,并接受了手术治疗。
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引用次数: 0
REFRACTIVE SURGERY FOR HIGH AMETROPIES, A FEW CONCLUSIONS. 高屈光度的屈光手术,几点结论。
Pub Date : 2015-04-01
Mircea Filip, Miruna Nicolae, Andrei Filip, Carmen Dragne, Grigorios Triantafillydis, Cristina Antonescu

This paper presents a few clinical cases of patients with high ametropies and/or anisometropia, who underwent one or two surgical procedures in our clinic, in order to obtain independence of glasses or contact lenses. Twenty cases of high ametropies were included in our study, with or without astigmatism, with transparent lenses, who presented in our clinic for surgical treatment to correct their refractive errors. Postoperatively, we analyzed the results and took decisions for each case in particular; sometimes a second surgical procedure was needed.

本文介绍了一些高度散光和/或无散光患者的临床病例,这些患者在本诊所接受了一到两次手术治疗,从而摆脱了眼镜或隐形眼镜的束缚。我们的研究共纳入了 20 例高度散光患者,他们或有散光,或无散光,均配戴透明镜片,在本诊所接受手术治疗,以矫正屈光不正。术后,我们对结果进行了分析,并根据每个病例的具体情况做出了决定;有时需要进行第二次手术。
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引用次数: 0
期刊
Romanian journal of ophthalmology
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