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Endometriosis of Postoperative Scar 瘢痕术后子宫内膜异位症
Pub Date : 2019-07-26 DOI: 10.5772/INTECHOPEN.88246
A. Plotski
Endometriosis in a postoperative scar is a secondary process in scars after surgical procedures affecting endometrium: cesarean section, hysterectomy, amniocentesis etc. Nevertheless scar endometriosis occurs also after general surgery – appendectomy, cholecystectomy, correction of hernias. The cause of surgical scar endometriosis is believed to be iatrogenic transplantation of endometrium to the surgical wound. Despite the ectopic location, endometrial tissue is able to respond to hormonal effects, thereby causing clinical signs of disease. Endometriosis of postoperative scar is a typical example of extragenital endometriosis. The most common presenting symptom of endometrioma in a scar is a palpable mass associated with cyclic pain and swelling during menses. When the patient complains are not cyclical (25-45% of patients with scar endometriosis) clinical diagnosis is impaired. The typical sonographic pattern of endometriomas is presence of subcutaneous nodule, hypoechoic with hyperechoic strands and irregular margins. Different types of hormonal therapy has been tried with minimal effects. That’s why for endometriosis of postoperative scar total surgical excision is considered to be golden standard for both diagnosis and treatment. In order to prevent scar endometriosis some measures have been proposed. But no measures of prevention have proved its efficiency and all these measures were suggested without any evident scientific corroboration.
术后瘢痕性子宫内膜异位症是影响子宫内膜的外科手术后瘢痕的继发过程,如剖宫产、子宫切除术、羊膜穿刺术等。然而,疤痕性子宫内膜异位症也发生在一般手术-阑尾切除术,胆囊切除术,疝气矫正术后。手术瘢痕性子宫内膜异位症的原因被认为是医源性子宫内膜移植到手术伤口。尽管位置异位,子宫内膜组织能够对激素的作用作出反应,从而引起疾病的临床症状。术后瘢痕性子宫内膜异位症是子宫外内膜异位症的典型。子宫内膜异位瘤最常见的症状是可触及的肿块,伴有月经期间的周期性疼痛和肿胀。当患者的主诉不是周期性的(占瘢痕性子宫内膜异位症患者的25-45%),临床诊断就会受损。子宫内膜异位瘤的典型声像图表现为皮下结节,低回声伴高回声线,边缘不规则。不同类型的激素疗法已经尝试过,但效果甚微。这就是为什么对于术后瘢痕的子宫内膜异位症,完全手术切除被认为是诊断和治疗的金标准。为了预防瘢痕性子宫内膜异位症,提出了一些措施。但没有任何预防措施证明其有效性,所有这些措施都是在没有明显的科学佐证的情况下提出的。
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引用次数: 1
The Specificities of Electrical Burn Healing 电烧伤愈合的特性
Pub Date : 2019-05-23 DOI: 10.5772/INTECHOPEN.83582
I. Ghorbel, S. Moalla, A. Abid, Amir Karra, K. Ennouri
Electrical burns are a major cause of bodily harm due to the mechanism and effect of the lesions. This prompts us to study these lesions and their management in order to reduce the morbidity caused by this type of accident. In the event of an electric chock accident, the treatment is medico-surgical and is composed of two main phases: acute phase when general treatment is essential and subacute phase when local treatment is implemented. The study shows that conventional emergency decompression does not appear to reduce the amputation rate, the use of local and locoregional flaps in the initial phase (<21 days) carries a significant risk of suffering and necrosis, and also antithrom-botic prevention or the use of flaps does not seem to have an impact on healing delays.
由于电烧伤的机制和影响,电烧伤是造成身体伤害的主要原因。这促使我们研究这些病变及其处理,以减少这类事故引起的发病率。在发生电窒息事故的情况下,治疗是外科手术治疗,分为两个主要阶段:急性阶段,需要进行一般治疗;亚急性阶段,需要进行局部治疗。研究表明,传统的紧急减压似乎并不能降低截肢率,在初始阶段(<21天)使用局部和局部区域皮瓣有明显的痛苦和坏死风险,而且抗血栓预防或使用皮瓣似乎对愈合延迟没有影响。
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引用次数: 0
Scarring After Burn Injury 烧伤后的疤痕
Pub Date : 2019-05-07 DOI: 10.5772/INTECHOPEN.85411
L. Damkat-Thomas, J. Greenwood
Burn injury is a trauma that has variable scarring outcomes dependent on both the size and the depth of the burn. This chapter will discuss the pathophysiology of wound healing by both primary and secondary intention and its applicability to burn wounds. The importance of accurate assessment of burn depth and its impact on the primary treatment and subsequent scar outcome will be explored. Special anatomic areas such as the face, hands and neck will be highlighted. Skin grafting and skin substitutes as treatment options will be reviewed. Improvements in burn care have enabled people to survive larger burns that may once have proved fatal. The emphasis of treatment, once healing has been achieved, is now focused upon rehabilitation and scar management. Scar management strategies including pressure garments and silicone therapy are highlighted along with secondary scar revision strategies.
烧伤是一种创伤,根据烧伤的大小和深度有不同的疤痕结果。本章将讨论伤口愈合的病理生理学,包括初级和次级意图及其在烧伤创面中的适用性。我们将探讨准确评估烧伤深度的重要性及其对初次治疗和后续疤痕结局的影响。面部、手部和颈部等特殊解剖区域将被突出显示。皮肤移植和皮肤替代品作为治疗选择将进行审查。烧伤护理的改进使人们能够在一度可能致命的更大烧伤中幸存下来。一旦实现愈合,治疗的重点现在集中在康复和疤痕管理上。疤痕管理策略,包括压力服装和硅胶治疗突出与二次疤痕修正策略。
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引用次数: 3
Scars: A New Point of View in Plastic Surgery 疤痕:整形外科的新观点
Pub Date : 2019-04-26 DOI: 10.5772/INTECHOPEN.84127
G. Prezzavento
The issue of achieving esthetically pleasing surgical scars has gained prominence in recent years, with the emergence of the concept of the “imperceptible scar,” which is expected by patients of not only cosmetic but also reconstructive surgery. Current research in reconstructive surgery focuses on obtaining high-quality results in the minimum number of steps, with a view to “doing it right the first time.” However, there is no uniform approach to scar treatment, which is partly due to a lack of consensus regarding the most effective healing methods. This chapter aims at shedding new light to discussion by putting forward two different procedures that enhance scar results in cosmetic and reconstructive surgeries by applying a topical treatment with active ingredients and by combining cadaver and artificial skin as dermal substitutes, respectively. The effectiveness of these treatments is shown by means of objective, quantifiable data collected as a result of studies and postoperative follow-ups carried out at Hospital Alemán in Buenos Aires.
近年来,随着“难以察觉的疤痕”概念的出现,实现美观的手术疤痕的问题日益突出,这不仅是整容手术,也是重建手术的患者所期望的。目前重建手术的研究重点是在最少的步骤中获得高质量的结果,以期“第一次就做对”。然而,没有统一的方法来治疗疤痕,这部分是由于缺乏共识关于最有效的愈合方法。本章旨在通过提出两种不同的程序,分别通过使用活性成分的局部治疗和将尸体皮肤和人造皮肤作为真皮替代品来增强美容和重建手术中的疤痕结果,从而为讨论提供新的亮点。这些治疗的有效性通过在布宜诺斯艾利斯Alemán医院进行的研究和术后随访所收集的客观、可量化的数据来证明。
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引用次数: 0
Keloids and Hypertrophic Scars Can Now Be Treated Completely by Multimodal Therapy, Including Surgery, Followed by Radiation and Corticosteroid Tape/Plaster 瘢痕疙瘩和增生性疤痕现在可以通过多模式治疗完全治疗,包括手术,随后是放疗和皮质类固醇胶布/石膏
Pub Date : 2019-02-08 DOI: 10.5772/INTECHOPEN.84178
R. Ogawa
Keloids and hypertrophic scars are fibroproliferative disorders of the skin. Research over the last decade has markedly improved our understanding of the pathogenesis of these scars, in particular, the fact that both disorders are caused by prolonged inflammation that prevents the orderly healing of injured or irritated skin. This protracted inflammatory response is due to genetic, systemic, and local risk factors. Genetic factors include single nucleotide polymorphisms, while systemic factors include hypertension, pregnancy-related and other hormones, and aberrant cytokine levels. An important local factor is the mechanical force (tension) on the scar. These observations have greatly aided the development of therapies for these once-intractable scars. As a result, these scars are now regarded as being completely treatable. At present, we believe that the following combination of three therapies most reliably achieves a complete cure: surgery followed by radiation and the prolonged daily use of corticosteroid tape/plaster. identifies four susceptibility loci for keloid in the population.
瘢痕疙瘩和增生性疤痕是皮肤的纤维增生性疾病。过去十年的研究已经显著提高了我们对这些疤痕发病机制的理解,特别是,这两种疾病都是由长期炎症引起的,这种炎症阻止了受伤或发炎皮肤的有序愈合。这种持续的炎症反应是由遗传、全身和局部危险因素引起的。遗传因素包括单核苷酸多态性,系统性因素包括高血压、妊娠相关激素及其他激素、细胞因子水平异常。一个重要的局部因素是疤痕上的机械力(张力)。这些观察结果极大地帮助了治疗这些曾经难治性疤痕的疗法的发展。因此,这些疤痕现在被认为是完全可以治疗的。目前,我们认为以下三种治疗方法的组合最可靠地实现完全治愈:手术后放疗和长期每日使用皮质类固醇胶布/石膏。确定人群中瘢痕疙瘩的四个易感位点。
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引用次数: 4
Percutaneous collagen induction (microneedling) for the management of non-atrophic scars: literature review 经皮胶原诱导(微针)治疗非萎缩性疤痕:文献综述
Pub Date : 2019-01-01 DOI: 10.1177/2059513119880301
Christos Iosifidis, I. Goutos
Introduction: Percutaneous collagen induction (PCI) or needling techniques are increasingly popular in the reconstructive and aesthetic arena. The underlying mechanisms of action rest on producing a pattern of non-ablative and non-confluent puncture wound pattern to the dermis with a resulting regenerative effect to the skin. Methods: A detailed English literature review was conducted using PubMed Medline, Embase and Web of Science; the manuscripts were appraised and classified according to level of evidence as well risk of bias. Results are presented in descending order of evidence for non-atrophic scars. Discussion: On the basis of level 1 evidence currently available, the combination of needling and silicone gel can improve the short-term pliability, height and vascularity of hypertrophic and keloid scars. According to level 2 evidence, needling alongside spray keratinocytes can produce a statistically significant improvement to patient/observer scar ratings and improve pigmentation in hypopigmented burn scars at 12-month follow-up. Results from mixed cohort studies also point towards needling having a beneficial effect on fat graft retention. Level 3 data suggest that needling can render significant resurfacing effects to both mature and actively hypertrophic burn scars at 12-month follow-up based on objective scar scales; furthermore, favourable histological changes are seen, including better collagen alignment in the dermis and increased epidermal thickness. Conclusion: Needling techniques are promising adjuncts to non-atrophic scar management. Further research with long-term follow-up and comparative design protocols incorporating other resurfacing modalities is warranted before the exact value of needling is delineated in scar management protocols. Lay Summary Needling techniques are increasingly popular and involve the use of a device to produce numerous tiny perforations in the skin, stimulate collagen production and resurface the treated area. We undertook this study to find out whether the use of needling can have a beneficial effect on scars that are raised (hypertrophic and keloidal). We conclude that, at present, there is some evidence that needling in combination with silicone gel can improve the appearance of bulky scars in the short term; additionally needling can enhance the appearance of discoloured burn scars if used in combination with spray skin cell preparations and improve the take of fat transferred to the treated area. There are also a number of studies that have confirmed the beneficial effects of needling in the architecture of treated skin, which include improved skin structure and increased collagen production. Further research is eagerly awaited to determine the exact position of needling techniques in scar management protocols.
导读:经皮胶原诱导(PCI)或针刺技术在重建和美学领域越来越受欢迎。潜在的作用机制在于产生一种非烧蚀性和非融合性的真皮层穿刺伤口模式,从而对皮肤产生再生效果。方法:采用PubMed Medline、Embase、Web of Science等软件进行详细的英文文献综述;根据证据水平和偏倚风险对稿件进行评估和分类。结果呈现在证据降序为非萎缩性疤痕。讨论:根据现有的1级证据,针刺和硅胶结合可以改善增生性瘢痕和瘢痕疙瘩的短期柔韧性、高度和血管性。根据二级证据,在12个月的随访中,针刺和喷雾角质形成细胞可以对患者/观察者的疤痕评分产生统计学上显著的改善,并改善低色素烧伤疤痕的色素沉着。混合队列研究的结果也指出,针刺对脂肪移植体保留有有益的影响。3级数据表明,在12个月的随访中,根据客观疤痕量表,针刺对成熟和活动性增生性烧伤疤痕都有显著的表面修复效果;此外,可以看到有利的组织学变化,包括真皮中更好的胶原排列和表皮厚度增加。结论:针刺技术是治疗非萎缩性瘢痕的有效辅助手段。在疤痕管理方案中明确针刺的确切价值之前,有必要进行长期随访和比较设计方案,并结合其他表面修复方式进行进一步研究。针刺技术越来越受欢迎,它包括使用一种装置在皮肤上产生许多微小的穿孔,刺激胶原蛋白的产生,并使治疗区域重新出现。我们进行这项研究是为了找出针刺是否对凸起的疤痕(肥厚性和瘢痕疙瘩)有有益的影响。我们的结论是,目前,有一些证据表明,针刺结合硅胶可以在短期内改善笨重疤痕的外观;此外,如果与喷雾皮肤细胞制剂结合使用,针刺可以增强变色烧伤疤痕的外观,并改善转移到治疗区域的脂肪的吸收。也有一些研究证实了针刺对治疗后皮肤结构的有益影响,包括改善皮肤结构和增加胶原蛋白的产生。进一步的研究迫切需要确定针刺技术在疤痕管理方案中的确切位置。
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引用次数: 14
SBH Reviewer list 2017 SBH评审员名单2017
Pub Date : 2018-05-21 DOI: 10.1177/2059513118759728
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引用次数: 0
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Scars, burns & healing
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