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Sexual behaviours and contraceptive use among undergraduates in a Nigerian University. 尼日利亚一所大学本科生的性行为和避孕药具使用情况。
Pub Date : 2024-07-02 DOI: 10.4314/gmj.v58i2.5
Olufunmilola O. Abolurin, Oluwabusola A. Akinbajo, Olusoji J. Daniel, Adesola O. Adekoya, Akinkunmi E. Akinbajo, Abiola O. Adekoya
Objectives: The study was conducted to describe the sexual behaviours and contraceptive use, as well as factors associated with being engaged in sex among Nigerian undergraduates.Design: A descriptive cross-sectional study.Setting: The study was conducted in a university of education in Ogun State, Nigeria.Participants: Four hundred undergraduates were selected sequentially through a stratified sampling method.Main outcome measures: Being sexually active, multiple sexual partners, and contraceptive use.Results: Participants’ ages ranged from 16 to 24 years. Nearly two-thirds (65.5%) were females. About a quarter of them (24.5%) were using psychoactive substance(s). More than two-fifths (44.5%) of them had engaged in sexual intercourse, of which 36% had a history of multiple sexual partners. The mean age at sexual debut was 18.7 ± 2.7 years, significantly lower among males than females (p <0.001). About half (218; 54.5%) of the students were cognisant of contraceptives, and 39.3% of sexually active participants had used contraceptives at some time, with condoms being the most commonly used. Male sex (p = 0.042), older age (p <0.001), higher monthly allowance (p = 0.025), and substance abuse (p <0.001) were factors that made undergraduates more likely to have engaged in sex.Conclusion: Engagement in sexual activity and unsafe sex were common practices among the Nigerian undergraduates studied. It is recommended that deliberate efforts be made to increase contraceptive awareness and usage.
研究目的本研究旨在描述尼日利亚大学生的性行为、避孕药具使用情况以及与性行为相关的因素:设计:描述性横断面研究:研究在尼日利亚奥贡州的一所教育大学进行:主要结果测量:主要结果测量指标:性活跃程度、多个性伴侣和避孕药具使用情况:结果:参与者的年龄在 16-24 岁之间。近三分之二(65.5%)为女性。其中约四分之一(24.5%)的人使用精神活性物质。超过五分之二(44.5%)的人有过性行为,其中 36% 有多个性伴侣史。初次性行为的平均年龄为 18.7 ± 2.7 岁,男性明显低于女性(P <0.001)。约有一半(218;54.5%)的学生了解避孕药具,39.3%的性活跃参与者曾经使用过避孕药具,其中最常用的是避孕套。男性(p = 0.042)、年龄较大(p <0.001)、每月津贴较高(p = 0.025)和药物滥用(p <0.001)是大学生更有可能发生性行为的因素:结论:参与性活动和不安全性行为是所研究的尼日利亚大学生的常见行为。建议刻意提高避孕意识和使用率。
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引用次数: 0
Helicopter research: A persistent drawback to equitable collaborative research 直升机研究:公平合作研究的顽疾
Pub Date : 2024-07-02 DOI: 10.4314/gmj.v58i2.1
Samuel Blay Nguah, Margaret Lartey
Collaboration in research has increased over the years with many advances in medical knowledge. With understanding and good faith, many of these partnerships have yielded remarkable results and significantly improved our world. The inequity has resulted in many untoward effects since much of this collaborative research is between persons from richer or high-income countries and poorer or lower-income ones. Helicopter Research or “parachute research” refers to the situation where a more resourced partner in a research collaboration goes into the less resourced partner's location, conducts research, exports the data, and publishes the findings, often with no or very little input from or acknowledgement of the less resourced counterpart. This does not only occur between richer and poorer nations but also even within the same country where the relationship is asymmetrical.
多年来,随着医学知识的不断进步,科研合作也日益增多。在相互理解和真诚的基础上,许多合作取得了显著成果,极大地改善了我们的世界。由于这种合作研究大多是在较富裕或高收入国家的人与较贫穷或低收入国家的人之间进行的,因此不平等造成了许多不良影响。直升机研究或 "空降研究 "是指在研究合作中,资源较多的伙伴进入资源较少的伙伴所在地,开展研究,输出数据,并发表研究结果,而资源较少的伙伴往往没有或很少提出意见或表示认可。这种情况不仅发生在富国和穷国之间,即使在关系不对称的同一国家内部也是如此。
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引用次数: 0
Recurrent ischemic stroke post-thrombolysis in an older Ghanaian woman 一名加纳老年妇女溶栓后复发缺血性中风
Pub Date : 2024-07-02 DOI: 10.4314/gmj.v58i2.9
Kwadwo F. Gyan, Priscilla A. Opare-Addo, Moses Siaw-Frimpong, Kwasi Ankomah, Fred S. Sarfo
Acute ischemic stroke management has evolved through several paradigms. Currently, thrombolysis is recommended for patients who present within 4.5 hours of acute ischemic stroke. Early neurological deterioration post-thrombolysis, however, may occur through several mechanisms. We report a case of a 66-year-old Ghanaian woman with multiple co-morbidities who presented with sudden onset right-sided weakness and aphasia of 2 hours duration. A diagnosis of acute ischemic stroke was made based on clinical examination and a computerised tomography scan of the brain. She underwent successful thrombolysis with recovery of full neurological function. She, however, developed a second ischemic stroke within 72 hours, with the likely aetiology being large vessel occlusion. This was subsequently managed conservatively. Extensive evaluation and control of specific stroke aetiologies is required for the prevention of stroke recurrence post thrombolysis. Also, the establishment of comprehensive stroke centres which provide neurovascular interventions in sub-Saharan Africa can help reduce stroke mortality and morbidity in eligible patients.
急性缺血性卒中的治疗经历了多种模式的演变。目前,建议对急性缺血性卒中 4.5 小时内发病的患者进行溶栓治疗。然而,溶栓后早期神经功能恶化可能通过多种机制发生。我们报告了一例 66 岁的加纳女性患者,她患有多种并发症,在 2 小时内突然出现右侧肢体无力和失语。根据临床检查和脑部计算机断层扫描,诊断为急性缺血性脑卒中。她接受了成功的溶栓治疗,神经功能完全恢复。然而,她在 72 小时内又发生了第二次缺血性中风,病因可能是大血管闭塞。随后她接受了保守治疗。为预防溶栓后中风复发,需要对特定中风病因进行广泛评估和控制。此外,在撒哈拉以南非洲建立提供神经血管介入治疗的综合性中风中心有助于降低符合条件的患者的中风死亡率和发病率。
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引用次数: 0
Factors associated with dual sensory impairment in older persons attending the Geriatric Centre in Southwest Nigeria 尼日利亚西南部老年医学中心就诊老年人双重感官障碍的相关因素
Pub Date : 2024-07-02 DOI: 10.4314/gmj.v58i2.3
Abiola O. Obadare, Lawrence A. Adebusoye, Eniola O. Cadmus
Objective: This study examined the prevalence of hearing impairment, visual impairment and Dual Sensory Impairment (DSI) and the risk factors among older personsDesign: A Cross-sectional study where respondents were recruited by systematic random sampling.Setting: A tertiary institution at the Geriatric Centre, University College Hospital, Ibadan, Nigeria.Participants: A total of 388 older persons aged more than 60 years were recruitedInterventions: A semi-structured pretested questionnaire was used over three months.Main outcome measures: Association between ageing, low income, poor quality of life, functional disability, and dual sensory impairment.Results: The mean age of the respondents was 70.2±6.3 years. The point prevalence of HI, VI and DSI were 14.9%, 8.0%, and 1.5% respectively. On logistic regression analysis, the most significant factors associated with HI were having no formal education OR=2.564(1.091-6.024) and previous hospital admission OR=3.473(1.856-6.499), for VI; increasing age OR=1.080(1.022-1.141) and poor income OR=2.941(1.263-6.897) and DSI; increasing age OR=1.224(1.054-1.421).Conclusion: Few (1.5%) older adults experienced DSI in our setting. The association between sensory impairments, age, and socioeconomic factors of poor education and income suggests the need for visual and hearing screening in older adults, particularly those with medical and socioeconomic issues, for early detection.
目的:本研究探讨了老年人中听力障碍、视力障碍和双重感官障碍(DSI)的发生率及风险因素:本研究调查了老年人中听力障碍、视力障碍和双重感官障碍(DSI)的患病率及其风险因素:横断面研究,通过系统随机抽样招募受访者:地点:尼日利亚伊巴丹大学学院医院老年医学中心的一所高等院校:共招募了 388 名 60 岁以上的老年人:主要结果测量:老龄化、低收入、生活质量差、功能性残疾和双重感官障碍之间的关系:受访者的平均年龄为 70.2±6.3 岁。HI、VI 和 DSI 的点患病率分别为 14.9%、8.0% 和 1.5%。根据逻辑回归分析,与 HI 相关的最重要因素是未受过正规教育 OR=2.564(1.091-6.024)和曾入院 OR=3.473(1.856-6.499);对于 VI,年龄越大 OR=1.080(1.022-1.141),收入越低 OR=2.941(1.263-6.897);对于 DSI,年龄越大 OR=1.224(1.054-1.421):结论:在我们的环境中,只有极少数(1.5%)老年人经历过 DSI。感官障碍、年龄、教育程度低和收入低等社会经济因素之间的关联表明,有必要对老年人,尤其是有医疗和社会经济问题的老年人进行视力和听力筛查,以便及早发现。
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引用次数: 0
Adherence to routinely prescribed medications among paediatric sickle cell disease patients in Kumasi, Ghana 加纳库马西镰状细胞病儿科患者对常规处方药的依从性
Pub Date : 2024-07-02 DOI: 10.4314/gmj.v58i2.2
Merlene A. Agyekum, Samuel B. Nguah, Joseph Attakorah, Gustav K. Nettey, Kwaku G. Oppong, Vivian Paintsil, Alex O. Akoto, Kwame O. Buabeng
Objective: To measure the adherence to routinely prescribed medications among Sickle Cell Disease (SCD) patients in Kumasi, GhanaDesign: A cohort study involving paediatric SCD patients presenting to the outpatient clinic at the Komfo Anokye Teaching Hospital (KATH).Setting: The Pediatric SCD Outpatient Clinic of KATH.Participants: Two hundred SCD patients visiting the outpatient clinicIntervention: NoneMain Outcome Measure: Cost and adherence to Penicillin V, Folic Acid, Hydroxyurea and Vitamins prescribed to SCD patients on routine outpatient visits.Results: Of the 200 participants, the highest and lowest phenotypes were Hb-SS (162, 80.1%) and Sβ-thal (3, 1.5%), respectively. The adherence rate to routine medications was 13.5% (95%CI: ut9.1% to 19.0%). Patient factors that affect adherence included forgetfulness 98(49%), cost 54(27%), and side effects 28(14%) of medication, and improvement in health 7(3.5%). Hydroxyurea was the costliest to the patients with a median (IQR) cost of GHc 75 (0, 450) or USD12 (0, 73), and the least was folic acid with a median of GHc 6 (0, 42) or USD 1 (0, 7). 44.5% of all medications prescribed were not obtained in full. 83% of those who did not purchase all the medicines attributed this to cost, with 13% indicating they had some at home.Conclusion: There is low adherence to routine medications used by SCD patients in Kumasi, and this could be because of their relatively high cost. Further studies should be made to assess the non-adherent effects of SCD medications on patients' health.
目的测量加纳库马西镰状细胞病(SCD)患者对常规处方药的依从性:一项队列研究,涉及在 Komfo Anokye 教学医院(KATH)门诊就诊的儿科 SCD 患者:地点: KATH的儿科SCD门诊:干预措施:主要结果测量:在常规门诊中为 SCD 患者开具青霉素 V、叶酸、羟基脲和维生素处方的费用和依从性:在 200 名参与者中,Hb-SS(162 人,占 80.1%)和 Sβ-thal(3 人,占 1.5%)分别是最高和最低的表型。常规用药依从率为 13.5%(95%CI:ut9.1% 至 19.0%)。影响坚持服药的患者因素包括健忘 98(49%)、费用 54(27%)、药物副作用 28(14%)以及健康状况改善 7(3.5%)。对患者来说,羟基脲的费用最高,中位数(IQR)为75加纳塞克(0,450)或12美元(0,73),叶酸的费用最低,中位数为6加纳塞克(0,42)或1美元(0,7)。在所有处方药中,44.5%的药物没有足额购买。在没有购买所有药品的人中,83%的人将原因归结为费用,13%的人表示家里有一些:结论:库马西的 SCD 患者对常规药物的依从性较低,这可能是因为这些药物的价格相对较高。应开展进一步的研究,以评估不坚持服用 SCD 药物对患者健康的影响。
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引用次数: 0
Rectal screening for carbapenemase-producing Enterobacteriaceae in an intensive care unit in India 印度重症监护病房对产碳青霉烯酶肠杆菌科细菌进行直肠筛查
Pub Date : 2024-07-02 DOI: 10.4314/gmj.v58i2.7
Arun Sachu, Sanjo Sunny, Philip Mathew, Ajeesh Kumar, Alice David
Objectives: To determine the proportion of patients admitted to ICU who are colonised with carbapenem-resistant Enterobacteriaceae (CRE) and to estimate the agreement between colonised patients and patients who developed an infection with CRE.Design: Prospective surveillance studySetting: The ICU of a tertiary care hospital in Kerala, IndiaParticipants: All patients above 18 were admitted to the ICU during the study period.Outcome measures: Patients colonised with CRE and systemic infection with the colonised organismResults: CRE colonisation was found in 20(8.7%) samples. Among the 20 patients in the study who were colonised with CRE, 5(25%) developed systemic infection due to CRE. History of antibiotic usage and admission to other hospitals in the last 90 days were independent predictors of CRE colonisation.Conclusion: Five of the 20 patients colonised with CRE developed an infection. Hospital admission and antibiotic usage were the main risk factors associated with CRE colonisation. Antibiotic escalation was suggested for two colonised patients based on their clinical worsening, but they succumbed to the illness. This study led us to modify our infection control practices, which led to isolating patients colonised with CRE.
目的确定重症监护病房收治的耐碳青霉烯类肠杆菌科细菌(CRE)定植患者的比例,并估计定植患者与感染 CRE 的患者之间的一致性:设计:前瞻性监测研究印度喀拉拉邦一家三级医院的重症监护室:研究期间入住重症监护室的所有 18 岁以上患者:结果:CRE定植患者和定植菌全身感染:在 20 份样本(8.7%)中发现了 CRE 定植。在20名CRE定植患者中,有5人(25%)因CRE引起全身感染。过去90天内有抗生素使用史和入住其他医院是CRE定植的独立预测因素:结论:在20名CRE定植患者中,有5人发生了感染。入院和使用抗生素是与 CRE 定植相关的主要风险因素。根据两名定植患者的临床恶化情况,我们建议对他们加强抗生素治疗,但他们最终还是病倒了。这项研究促使我们修改了感染控制措施,从而隔离了CRE定植患者。
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引用次数: 0
Prognostic significance of morphology markers of chromosomal instability in acute leukaemia and myelodysplastic syndrome 急性白血病和骨髓增生异常综合征染色体不稳定形态标记的预后意义
Pub Date : 2024-07-02 DOI: 10.4314/gmj.v58i2.6
Anju Khairwa, M. Kotru, Pooja Dewan, Shiva Narang
Objective: This study aimed to assess the prognostic significance of various morphological markers of chromosomal instability (CI).Design: This is a cross-sectional analytical study.Setting: Single centre study from the Department of Pathology of a tertiary care centre in India.Participants: The study included samples of bone marrow aspirates (BMA) and biopsies of patients with acute leukaemia (AL) and myelodysplastic syndrome (MDS) performed between June 2019 and June 2021. Inadequate samples were excluded. We included 178 samples from 80 cases.Interventions: BMA and biopsies slides examined for CI markers like chromatin bridges, multipolar mitosis, nuclear budding, micronuclei, laggards, chromatin string (CS) and nuclear heterogeneity (NH). CI markers were correlated with the type, severity and prognosis of acute leukaemia and MDS.Main outcome measures: Evaluation of CI markers as prognostic markers in AL and MDS.Results: We included B-cell ALL (35), AML (11), MDS (04), relapse of AL (12), and remission of AL (116). All CI markers were significantly increased in AL and MDS compared to the remission group. All CI markers were significantly higher in non-responders to therapy than in responders. In regression analysis, the median (IQR) values of CS and NH were significantly higher among non-survivors than survivors.Conclusion: CI markers of morphology are significantly associated with poor prognosis, including Non-survival of the disease. These markers are easy to identify and cost-effective. We recommend incorporating morphological markers of CI in routine reporting of haematological malignancies to assist in prognostication before reports from sophisticated techniques are available.
研究目的本研究旨在评估染色体不稳定性(CI)各种形态学标志物的预后意义:这是一项横断面分析研究:印度一家三级医疗中心病理科的单中心研究:研究包括2019年6月至2021年6月期间进行的急性白血病(AL)和骨髓增生异常综合征(MDS)患者的骨髓穿刺(BMA)和活检样本。不足的样本被排除在外。我们纳入了来自 80 个病例的 178 份样本:BMA和活检切片检查染色质桥、多极有丝分裂、核出芽、微核、落后者、染色质串(CS)和核异质性(NH)等CI标记物。CI标记与急性白血病和MDS的类型、严重程度和预后相关:主要结果指标:评估作为AL和MDS预后标志物的CI标志物:我们纳入了B细胞ALL(35例)、AML(11例)、MDS(04例)、AL复发(12例)和AL缓解(116例)。与缓解组相比,AL和MDS的所有CI标志物均明显升高。治疗无反应者的所有 CI 指标均明显高于有反应者。在回归分析中,非存活者的 CS 和 NH 中位值(IQR)明显高于存活者:结论:CI 形态学标志物与不良预后(包括非存活)密切相关。这些标志物易于识别且具有成本效益。我们建议在血液恶性肿瘤的常规报告中纳入 CI 形态学标志物,以便在获得复杂技术报告之前协助预后判断。
{"title":"Prognostic significance of morphology markers of chromosomal instability in acute leukaemia and myelodysplastic syndrome","authors":"Anju Khairwa, M. Kotru, Pooja Dewan, Shiva Narang","doi":"10.4314/gmj.v58i2.6","DOIUrl":"https://doi.org/10.4314/gmj.v58i2.6","url":null,"abstract":"Objective: This study aimed to assess the prognostic significance of various morphological markers of chromosomal instability (CI).Design: This is a cross-sectional analytical study.Setting: Single centre study from the Department of Pathology of a tertiary care centre in India.Participants: The study included samples of bone marrow aspirates (BMA) and biopsies of patients with acute leukaemia (AL) and myelodysplastic syndrome (MDS) performed between June 2019 and June 2021. Inadequate samples were excluded. We included 178 samples from 80 cases.Interventions: BMA and biopsies slides examined for CI markers like chromatin bridges, multipolar mitosis, nuclear budding, micronuclei, laggards, chromatin string (CS) and nuclear heterogeneity (NH). CI markers were correlated with the type, severity and prognosis of acute leukaemia and MDS.Main outcome measures: Evaluation of CI markers as prognostic markers in AL and MDS.Results: We included B-cell ALL (35), AML (11), MDS (04), relapse of AL (12), and remission of AL (116). All CI markers were significantly increased in AL and MDS compared to the remission group. All CI markers were significantly higher in non-responders to therapy than in responders. In regression analysis, the median (IQR) values of CS and NH were significantly higher among non-survivors than survivors.Conclusion: CI markers of morphology are significantly associated with poor prognosis, including Non-survival of the disease. These markers are easy to identify and cost-effective. We recommend incorporating morphological markers of CI in routine reporting of haematological malignancies to assist in prognostication before reports from sophisticated techniques are available.","PeriodicalId":94319,"journal":{"name":"Ghana medical journal","volume":"19 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of sonographically-determined residual urine volume with lower urinary tract symptoms in adult males at a tertiary hospital 一家三级医院成年男性超声波测定的残余尿量与下尿路症状的相关性
Pub Date : 2024-07-02 DOI: 10.4314/gmj.v58i2.4
Linda Nketiah, K. Dzefi-Tettey, Raphael N. Mayeden, Ambrose Agborli, Benard Ohene- Botwe, Yaw B. Mensah
Objective: To determine the correlation between the severity of LUTS as measured by the International Prostate Symptom Score (IPSS) and PVR urine volume measured by transabdominal ultrasound in patients with LUTS, and to determine the correlation between ‘feeling of incomplete bladder emptying and sonographically measured PVR urine volume.Design: Correlational cross-sectional studySetting: Ultrasound Unit of the Radiology Department and Urology Clinic of Korle Bu Teaching HospitalParticipants: Male patients (n=256) aged 40 years or older who presented to the urology department of Korle Bu Teaching Hospital with LUTS and gave their written consent were enrolled. The presence and severity of LUTS were evaluated using the IPSS. The PVR urine was measured using a real-time transabdominal ultrasound scan.Main outcome measure: Severity of LUTS and Residual urine volumeResults: The mean PVR urine volume was 84.5ml. Most respondents (57.3%, n=146) had PVR urine volume below 50ml, with 27% (70 patients) having PVR urine volume above 100ml. PVR urine volume and total IPSS showed no statistically significant correlation. All age groups of respondents scored above 4 for Quality of life (QoL). ‘Intermittency’ is the IPSS symptom, which showed a statistically significant correlation with PVR urine volume. PVR urine volume did not correlate statistically with the ‘feeling of incomplete emptying’.Conclusions: There was no statistically significant correlation between the total IPSS and PVR urine volume. Thus, residual urine volume does not correlate with the severity of LUTS. The ‘feeling of incomplete emptying’ does not correlate with PVR urine volume.
目的确定通过国际前列腺症状评分(IPSS)测量的 LUTS 患者 LUTS 严重程度与经腹超声波测量的 PVR 尿量之间的相关性,并确定 "膀胱排空不完全感 "与超声波测量的 PVR 尿量之间的相关性:设置:放射科超声室地点:科勒布教学医院放射科和泌尿科超声波室参与者:男性患者(n=256)、女性患者(n=256)和男性患者(n=256):科勒布教学医院泌尿科就诊的尿失禁男性患者(n=256),年龄在40岁或40岁以上,并出具书面同意书。采用 IPSS 评估 LUTS 的存在和严重程度。主要结果指标:LUTS严重程度和残余尿量:平均 PVR 尿量为 84.5 毫升。大多数受访者(57.3%,n=146)的 PVR 尿量低于 50 毫升,27%(70 名患者)的 PVR 尿量高于 100 毫升。PVR 尿量与总 IPSS 在统计学上无显著相关性。所有年龄组的受访者在生活质量(QoL)方面的得分都在 4 分以上。间歇性 "是一种 IPSS 症状,在统计学上与 PVR 尿量有显著相关性。PVR 尿量与 "排空不完全感 "没有统计学相关性:结论:总 IPSS 与 PVR 尿量之间没有统计学意义上的相关性。因此,残余尿量与 LUTS 的严重程度无关。排空不完全感 "与 PVR 尿量无关。
{"title":"Correlation of sonographically-determined residual urine volume with lower urinary tract symptoms in adult males at a tertiary hospital","authors":"Linda Nketiah, K. Dzefi-Tettey, Raphael N. Mayeden, Ambrose Agborli, Benard Ohene- Botwe, Yaw B. Mensah","doi":"10.4314/gmj.v58i2.4","DOIUrl":"https://doi.org/10.4314/gmj.v58i2.4","url":null,"abstract":"Objective: To determine the correlation between the severity of LUTS as measured by the International Prostate Symptom Score (IPSS) and PVR urine volume measured by transabdominal ultrasound in patients with LUTS, and to determine the correlation between ‘feeling of incomplete bladder emptying and sonographically measured PVR urine volume.Design: Correlational cross-sectional studySetting: Ultrasound Unit of the Radiology Department and Urology Clinic of Korle Bu Teaching HospitalParticipants: Male patients (n=256) aged 40 years or older who presented to the urology department of Korle Bu Teaching Hospital with LUTS and gave their written consent were enrolled. The presence and severity of LUTS were evaluated using the IPSS. The PVR urine was measured using a real-time transabdominal ultrasound scan.Main outcome measure: Severity of LUTS and Residual urine volumeResults: The mean PVR urine volume was 84.5ml. Most respondents (57.3%, n=146) had PVR urine volume below 50ml, with 27% (70 patients) having PVR urine volume above 100ml. PVR urine volume and total IPSS showed no statistically significant correlation. All age groups of respondents scored above 4 for Quality of life (QoL). ‘Intermittency’ is the IPSS symptom, which showed a statistically significant correlation with PVR urine volume. PVR urine volume did not correlate statistically with the ‘feeling of incomplete emptying’.Conclusions: There was no statistically significant correlation between the total IPSS and PVR urine volume. Thus, residual urine volume does not correlate with the severity of LUTS. The ‘feeling of incomplete emptying’ does not correlate with PVR urine volume.","PeriodicalId":94319,"journal":{"name":"Ghana medical journal","volume":"75 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141688503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Angiographic severity of coronary artery disease and the influence of major cardiovascular risk factors. 冠状动脉疾病的血管造影严重程度和主要心血管风险因素的影响。
Pub Date : 2023-12-01 DOI: 10.4314/gmj.v57i4.2
Nehemiah J Dung, Mark M Tettey, Martin Tamatey, Lawrence A Sereboe, Alfred Doku, Martin Adu-Adadey, Francis Agyekum

Objective: To determine the angiographic severity of coronary artery disease (CAD) and assess the influence of major cardiovascular risk factors (CVRF).

Study design: a cross-sectional, hospital-based study.

Setting: the catheterisation laboratory of the National Cardiothoracic Centre, Accra, Ghana.

Participants: for 12 months, consecutive patients admitted for coronary angiography were assessed for the presence of CVRFs. Those with significant CAD after angiography were recruited into the study.

Intervention: The patient's angiograms were analysed, and the CAD severity was obtained using the SYNTAX scoring criteria.

Main outcome measure: The lesion overall severity (SYNTAX) score and the relationship with CVRFs present.

Results: out of the 169 patients that had coronary angiography, 78 had significant CAD. The mean SYNTAX score was 20.18 (SD= 10.68), with a significantly higher value in dyslipidaemic patients (p < 0.001). Pearson's correlation between the score and BMI was weak (r= 0.256, p= 0.034). The occurrence of high SYNTAX score lesions in about 18% of the population was significantly associated with hypertension (OR= 1.304, 95% CI [1.13-1.50]; p= 0.017) dyslipidaemia (OR= 5.636, 95% CI [1.17-27.23]; p= 0.019), and obesity (OR= 3.960, 95% CI [1.18-13.34]; p= 0.021). However, after adjusting for confounding factors, only dyslipidaemia significantly influenced its occurrence (aOR= 5.256, 95% CI [1.03-26.96]; p= 0.047).

Conclusion: Even though the most severe form of CAD was found in about one-fifth of the study population, its occurrence was strongly influenced by the presence of dyslipidaemia.

Funding: None.

研究目的确定冠状动脉疾病(CAD)的血管造影严重程度,并评估主要心血管风险因素(CVRF)的影响。研究设计:一项横断面、基于医院的研究。干预措施:在 12 个月内,对连续接受冠状动脉造影术的患者进行评估,以确定是否存在 CVRFs:主要结果指标:病变总体严重程度(SYNTAX)评分以及与存在的 CVRFs 的关系。结果:在 169 名接受冠状动脉造影术的患者中,78 人患有明显的 CAD。平均 SYNTAX 得分为 20.18(SD= 10.68),血脂异常患者的得分明显更高(P < 0.001)。得分与体重指数之间的皮尔逊相关性较弱(r= 0.256,p= 0.034)。约 18% 的人群出现 SYNTAX 高分病变与高血压(OR= 1.304,95% CI [1.13-1.50];p= 0.017)、血脂异常(OR= 5.636,95% CI [1.17-27.23];p= 0.019)和肥胖(OR= 3.960,95% CI [1.18-13.34];p= 0.021)显著相关。然而,在对混杂因素进行调整后,只有血脂异常对其发生有显著影响(aOR= 5.256,95% CI [1.03-26.96];p= 0.047):结论:尽管研究人群中约有五分之一患有最严重形式的 CAD,但血脂异常对其发生有很大影响:无。
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引用次数: 0
Idiopathic parietal bone thinning mimicking a bone lesion. 模仿骨病变的特发性顶骨变薄。
Pub Date : 2023-12-01 DOI: 10.4314/gmj.v57i4.10
Thomas Saliba, Alessandro De Leucio, Paolo Simoni

Idiopathic focal unilateral skull thinning is a rare finding. An explanation, such as trauma or disease, can often be found. However, in some cases, no explanation is forthcoming, and thus, we must look further into their history for a possible cause. The case of a nine-year-old boy with a crescent-shaped unilateral parietal bone thinning and a history of ventouse-assisted birth is presented. The lesion matches a ventouse's typical location, shape, and size. Thus, with the support of one other reported similar case, we hypothesise this may be the origin. We present the case of a crescent-shaped lesion matching the imprint of a ventouse in a child with a concordant history. This finding is put in the context of similar reports in the literature, and we believe that this report provides further evidence of this obscure phenomenon.

Funding: None declared.

特发性局灶性单侧颅骨变薄是一种罕见的病症。通常可以找到一种解释,如外伤或疾病。然而,在某些病例中,我们无法找到任何解释,因此必须进一步了解病史,寻找可能的病因。本病例是一个 9 岁男孩的病例,他的单侧顶骨呈新月形变薄,并有文氏助产史。病变的位置、形状和大小均符合通风孔的典型特征。因此,在另一例类似病例的支持下,我们推测这可能就是病因。我们介绍了一个病例,该病例患儿的新月形病变与文鸟的印记相吻合,且病史一致。我们将这一发现与文献中的类似报告结合起来,认为本报告为这一不明显的现象提供了进一步的证据:未声明。
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引用次数: 0
期刊
Ghana medical journal
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