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Dental treatments under sedation-analgesia in patients who are unable to collaborate: a prospective observational study. 无法合作的患者在镇静镇痛下接受牙科治疗:一项前瞻性观察研究。
Pub Date : 2024-06-01 Epub Date: 2024-05-27 DOI: 10.17245/jdapm.2024.24.3.173
Carlos M Cobo Vázquez, Mⷶ Carmen Gasco

Background: Excessive fear of dental procedures leads to disruptive behavior during dental examinations and treatments. Dental examinations and treatments of these patients usually require additional techniques, such as sedation. The most commonly used techniques are inhalation of nitrous oxide, infusion of propofol with fentanyl, and premedication and infusion of midazolam.

Methods: A prospective observational epidemiological study was conducted on patients who required sedoanalgesia techniques for dental exploration and procedures. The reasons for the inability of patients to cooperate (excessive fear or intellectual disability), age, sex, weight, systemic pathology, oral pathology, treatment performed, time of intervention, anesthetic technique performed, and occurrence of complications were recorded.

Results: In total, 218 patients were studied. Sixty-five patients came for fear of dental treatment and 153 for presenting with a diagnosis of intellectual disability and not collaborating in the treatment with local anesthesia. The average age of all patients was 30.54 ± 17.30 years. The most frequent oral pathologies found in patients with excessive fear were tartar (6.8%) and wisdom teeth (6.4%), followed by missing teeth (5%). In patients with disabilities, a combination of tartar and cavities appeared most frequently (41.3%), followed by cavities (15.6%). The most frequently used sedoanalgesia technique was the infusion of propofol with fentanyl in both groups of patients, followed by nitrous oxide.

Conclusion: The combination of propofol and fentanyl was the most frequently used alternative in patients who were unable to collaborate because of intellectual disability or carry out longer or more complex treatments. Inhaled nitrous oxide and midazolam were the sedative techniques of choice for simpler oral treatments, such as tartrectomies, shallow obturations, and shorter interventions, or in younger patients.

背景:对牙科程序的过度恐惧会导致在牙科检查和治疗过程中出现破坏性行为。对这些患者进行牙科检查和治疗通常需要额外的技术,如镇静剂。最常用的技术是吸入氧化亚氮、输注丙泊酚和芬太尼,以及预处理和输注咪达唑仑:对牙科探查和手术中需要使用镇静镇痛技术的患者进行了一项前瞻性流行病学观察研究。研究记录了患者无法合作的原因(过度恐惧或智力障碍)、年龄、性别、体重、全身病变、口腔病变、已实施的治疗、干预时间、已实施的麻醉技术以及并发症的发生情况:共研究了 218 名患者。65名患者因害怕牙科治疗而前来就诊,153名患者因被诊断为智力障碍而不配合局部麻醉治疗。所有患者的平均年龄为(30.54 ± 17.30)岁。过度恐惧患者最常见的口腔疾病是牙石(6.8%)和智齿(6.4%),其次是缺牙(5%)。在残疾患者中,牙垢和龋齿并存的情况最常见(41.3%),其次是龋齿(15.6%)。在两组患者中,最常用的镇静镇痛技术是输注异丙酚和芬太尼,其次是氧化亚氮:异丙酚和芬太尼的组合是因智力障碍而无法合作或进行较长时间或较复杂治疗的患者最常使用的替代方法。吸入氧化亚氮和咪达唑仑是较简单的口腔治疗(如牙槽切除术、浅钝术和较短的介入治疗)或较年轻患者的首选镇静技术。
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引用次数: 0
Novel dental anesthetic and associated devices: a scoping review. 新型牙科麻醉剂及相关设备:范围界定综述。
Pub Date : 2024-06-01 Epub Date: 2024-05-27 DOI: 10.17245/jdapm.2024.24.3.161
Kyung Hyuk Min, Zac Morse

The efficient management of pain and discomfort is essential for successful dental treatment and patient compliance. Dental professionals are commonly evaluated for their ability to perform treatment with minimal patient discomfort. Despite advancements in traditional local dental anesthesia techniques, the pain and discomfort associated with injections remain a concern. This scoping review aims to provide a comprehensive overview of the literature on novel dental anesthetics and associated devices designed to alleviate pain and discomfort during dental procedures. The Joanna Briggs Institute and the Preferred Reporting Items for Systematic reviews and Meta-Analyses Extension for Scoping Reviews guidelines were used to prepare the review. Six databases and two sources of gray literature were searched. This review analyzed 107 sources from 1994 to 2023. Local anesthesia devices were grouped into computer-controlled local anesthetic delivery (CCLAD) systems, intraosseous anesthesia (IOA), vibratory stimulation devices, and electronic dental anesthesia (EDA). CCLAD systems, particularly the Wand and Single-Tooth Anesthesia, have been the most researched, with mixed results regarding their effectiveness in reducing pain during needle insertion compared to traditional syringes. However, CCLAD systems often demonstrated efficacy in reducing pain during anesthetic deposition, especially during palatal injections. Limited studies on IOA devices have reported effective pain alleviation. Vibrating devices have shown inconsistent results in terms of pain reduction, with some studies suggesting their primary benefit is during needle insertion rather than during the administration phase. EDA devices are effective in reducing discomfort but have found limited applicability. These findings suggest that the CCLAD systems reduce injection pain and discomfort. However, the evidence for other devices is limited and inconsistent. The development and research of innovative technologies for reducing dental pain and anxiety provides opportunities for interdisciplinary collaboration and improved patient care in dental practice.

有效控制疼痛和不适对成功的牙科治疗和患者的依从性至关重要。对牙科专业人员的评估通常是看他们是否有能力在进行治疗时将患者的不适感降到最低。尽管传统的局部牙科麻醉技术不断进步,但与注射相关的疼痛和不适仍是一个令人担忧的问题。本范围综述旨在提供有关新型牙科麻醉剂和相关设备的文献综述,以减轻牙科治疗过程中的疼痛和不适。本综述采用了乔安娜-布里格斯研究所(Joanna Briggs Institute)和《系统综述和元分析的首选报告项目》(Preferred Reporting Items for Systematic reviews and Meta-Analyses Extension for Scoping Reviews)指南。检索了六个数据库和两个灰色文献来源。本综述分析了 1994 年至 2023 年的 107 篇文献。局部麻醉设备分为计算机控制局部麻醉给药(CCLAD)系统、鞘内麻醉(IOA)、振动刺激设备和电子牙科麻醉(EDA)。与传统注射器相比,CCLAD 系统在减少针头插入时的疼痛方面效果不一。不过,CCLAD 系统在减少麻醉剂沉积过程中的疼痛,尤其是腭部注射过程中的疼痛方面往往表现出效果。关于 IOA 装置的有限研究报告称其能有效减轻疼痛。振动装置在减轻疼痛方面的效果并不一致,一些研究表明,振动装置的主要益处是在针头插入时,而不是在给药阶段。EDA 装置可有效减轻不适感,但适用性有限。这些研究结果表明,CCLAD 系统可减少注射疼痛和不适。然而,其他装置的证据有限且不一致。减少牙科疼痛和焦虑的创新技术的开发和研究为牙科实践中的跨学科合作和改善患者护理提供了机会。
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引用次数: 0
Anesthetic management of a large mandibular odontogenic myxoma in a child - a case report. 儿童巨大下颌骨牙源性肌瘤的麻醉处理--病例报告。
Pub Date : 2024-06-01 Epub Date: 2024-05-27 DOI: 10.17245/jdapm.2024.24.3.213
Koovakattil Akhil Kuttan, Sri Rama Ananta Nagabhushanam Padala, Anagha P Vinay, Kuruba Aravind, Molli Kiran

Numerous neoplastic lesions can arise in the orofacial region in the pediatric populations. Odontogenic tumors typically affect the mandible more than the maxilla. Airway management can be challenging in pediatric oral tumors because of the distorted anatomy and physiological variations. Conventional awake fiberoptic intubation is not always possible owing to limited cooperation from the pediatric populations. Herein, we report the case of a 1-year-old child with odontogenic myxoma of the mandible and an anticipated difficult airway. Given the expected difficulties in the airway, video laryngoscope-assisted orotracheal intubation under general anesthesia with maintenance of spontaneous breathing was scheduled. Proper planning and thorough examinations are vital for successful airway management in pediatric patients.

在儿科人群中,口面部可出现许多肿瘤性病变。牙源性肿瘤对下颌骨的影响通常大于上颌骨。由于解剖结构的扭曲和生理上的差异,小儿口腔肿瘤的气道管理具有挑战性。由于儿科患者的配合度有限,传统的清醒纤支镜插管并不总是可行。在此,我们报告了一例患有下颌骨牙源性肌瘤的 1 岁儿童的病例,该患儿的气道预计会很困难。鉴于预计气道会出现困难,我们安排在全身麻醉下进行视频喉镜辅助气管插管,并维持自主呼吸。正确的计划和全面的检查对成功处理儿科患者的气道至关重要。
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引用次数: 0
Trends in behavioral management techniques for dental treatment of patients with autism spectrum disorder: a 10-year retrospective analysis. 自闭症谱系障碍患者牙科治疗行为管理技术的发展趋势:10 年回顾性分析。
Pub Date : 2024-06-01 Epub Date: 2024-05-27 DOI: 10.17245/jdapm.2024.24.3.187
Gahee Son, Sohee Oh, Jaehee Lee, Saeromi Jun, Jongbin Kim, Jongsoo Kim, Joonhaeng Lee, Miran Han, Jisun Shin

Background: Patients with autism spectrum disorder (ASD) present challenges in dental treatment cooperation owing to deficits in communication skills and social interaction. Behavioral guidance, sedation, and general anesthesia may be employed to ensure the quality of dental care for individuals with ASD. This study aimed to examine the trends in dental treatment for patients with ASD who visited the Department of Pediatric Dentistry at Dankook University Jukjeon Dental Hospital, an oral health center for the disabled in the Gyeonggi region, over the past 10 years.

Methods: This study utilized the order communication system to gather data on sex, age, cooperation level, number of quadrants treated, and administration of sedation or general anesthesia for patients with ASD who visited the Department of Pediatric Dentistry at Dankook University Jukjeon Dental Hospital between January 2013 and December 2022.

Results: The total number of patients with ASD increased annually, possibly due to an increase in ASD prevalence and the hospital's designation as a center for disabled oral health. General anesthesia was predominant before 2017, with a shift towards N2O-O2 sedation. The most common age group for sedation or general anesthesia was 6-9 years, with a higher prevalence in males than in females. Notably, N2O-O2 and midazolam sedation resulted in better cooperation and fewer treated teeth than general anesthesia.

Conclusion: This study highlights the evolving trends in dental treatment for individuals with ASD, indicating a shift towards outpatient methods, particularly N2O-O2 sedation. The sex distribution aligns with national statistics, emphasizing a higher prevalence of ASD in males than in females. These findings underscore the need for further research to establish evidence-based guidelines for optimal dental care strategies tailored to the unique needs of individuals with ASD.

背景:自闭症谱系障碍(ASD)患者由于在沟通技能和社会交往方面存在缺陷,在牙科治疗合作方面面临挑战。为确保自闭症谱系障碍患者的牙科治疗质量,可采用行为指导、镇静和全身麻醉等方法。本研究旨在探讨过去10年中在京畿地区残疾人口腔医疗中心--檀国大学竹田牙科医院儿童牙科就诊的ASD患者的牙科治疗趋势:本研究利用订单通信系统收集了2013年1月至2022年12月期间在檀国大学竹田口腔医院儿童牙科就诊的ASD患者的性别、年龄、合作程度、治疗象限数、镇静剂或全身麻醉的使用情况等数据:ASD患者的总人数逐年增加,这可能是由于ASD发病率增加以及医院被指定为残疾人口腔健康中心。2017年之前,全身麻醉占主导地位,之后转向N2O-O2镇静。镇静或全身麻醉最常见的年龄组为 6-9 岁,男性的发病率高于女性。值得注意的是,与全身麻醉相比,N2O-O2 和咪达唑仑镇静法的合作性更好,治疗的牙齿数量更少:本研究强调了ASD患者牙科治疗的发展趋势,表明了向门诊治疗方法的转变,尤其是N2O-O2镇静法。性别分布与全国统计数据一致,强调男性 ASD 患病率高于女性。这些发现强调了进一步研究的必要性,以便为针对 ASD 患者独特需求的最佳牙科护理策略制定循证指南。
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引用次数: 0
Bell's palsy after concomitant chemoradiotherapy: a case report and literature review. 同时接受放化疗后的贝尔麻痹:病例报告和文献综述。
Pub Date : 2024-04-01 Epub Date: 2024-03-28 DOI: 10.17245/jdapm.2024.24.2.129
Sul Gi Choi, Ji Seok Oh, Hoon Myoung, Mi Hyun Seo

Concomitant chemoradiotherapy (CCRT) treated patients experience various complications. We present a rare case of post-CCRT Bell's palsy and describe its various possible causes, so as to increase awareness among clinicians about Bell's palsy being a CCRT-associated adverse effect. The patient was a 48-year-old man diagnosed with squamous cell carcinoma who presented with post-CCRT Bell's palsy. After radiotherapy for 6 weeks (overall 67.5 Gy) and four rounds of cisplatin chemotherapy, he complained of paralysis of the entire left face. A test was performed 33 days after the last CCRT session to differentiate Bell's palsy from other causative factors. Based on magnetic resonance imaging findings, facial nerve invasion due to tumor size increase was determined to not cause Bell's palsy. Inflammation of the left Eustachian tube was observed. Hence, steroids and famciclovir were administered, which markedly improved the facial paralysis symptoms within 56 days after facial paralysis development. In conclusion, patients can develop Bell's palsy owing to complex effects of various CCRT mechanisms. Although the exact cause of Bell's palsy has not been identified and the effectiveness of drug treatment was questionable in this case, unlikely causative factors should be excluded through various tests and appropriate and timely measures must be adopted.

接受同步放化疗(CCRT)治疗的患者会出现各种并发症。我们介绍了一例罕见的CCRT后贝尔氏麻痹病例,并描述了各种可能的原因,以提高临床医生对CCRT相关不良反应贝尔氏麻痹的认识。患者是一名 48 岁的男性,被诊断为鳞状细胞癌,出现了 CCRT 后贝尔氏麻痹。在接受了 6 周的放疗(总剂量为 67.5 Gy)和四轮顺铂化疗后,他主诉整个左脸麻痹。为了将贝尔氏麻痹与其他致病因素区分开来,在最后一次 CCRT 治疗后 33 天进行了检查。根据磁共振成像结果,确定肿瘤增大导致的面神经侵犯不会引起贝尔氏麻痹。观察到左侧咽鼓管发炎。因此,患者接受了类固醇和泛昔洛韦治疗,并在面瘫发生后的56天内明显改善了面瘫症状。总之,患者可能会因各种 CCRT 机制的复杂影响而患上贝尔氏瘫痪。虽然贝尔麻痹的确切病因尚未确定,药物治疗的效果在本病例中也值得怀疑,但应通过各种检查排除不可能的致病因素,并采取适当和及时的措施。
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引用次数: 0
Unexpected airway foreign body during general anesthesia. 全身麻醉期间气道意外异物。
Pub Date : 2024-04-01 Epub Date: 2024-03-28 DOI: 10.17245/jdapm.2024.24.2.137
Naotaka Kishimoto, Yutaka Tanaka, Shigenobu Kurata, Kenji Seo
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引用次数: 0
Nasotracheal intubation in pediatrics: a narrative review. 儿科鼻气管插管:叙述性综述。
Pub Date : 2024-04-01 Epub Date: 2024-03-28 DOI: 10.17245/jdapm.2024.24.2.81
Jieun Kim, Sooyoung Jeon

Nasotracheal intubation (NTI) plays an important role in pediatric airway management, offering advantages in specific situations, such as oral and maxillofacial surgery and situations requiring stable tube positioning. However, compared to adults, NTI in children presents unique challenges owing to anatomical differences and limited space. This limited space, in combination with a large tongue and short mandible, along with large tonsils and adenoids, can complicate intubation. Owing to the short tracheal length in pediatric patients, it is crucial to place the tube at the correct depth to prevent it from being displaced due to neck movements, and causing injury to the glottis. The equipment used for NTI includes different tube types, direct laryngoscopy vs. video laryngoscopy, and fiberoptic bronchoscopy. Considering pediatric anatomy, the advantages of video laryngoscopy have been questioned. Studies comparing different techniques have provided insights into their efficacy. Determining the appropriate size and depth of nasotracheal tubes for pediatric patients remains a challenge. Various formulas based on age, weight, and height have been explored, including the recommendation of depth-mark-based NTI. This review provides a comprehensive overview of NTI in pediatric patients, including the relevant anatomy, equipment, clinical judgment, and possible complications.

鼻气管插管(NTI)在儿科气道管理中发挥着重要作用,在特定情况下具有优势,如口腔颌面外科手术和需要稳定插管定位的情况。然而,与成人相比,由于解剖结构的差异和有限的空间,儿童气管插管(NTI)面临着独特的挑战。由于空间有限,再加上舌头大、下颌骨短、扁桃体和腺样体大,插管可能会变得复杂。由于儿童患者的气管长度较短,因此必须将插管放置在正确的深度,以防止插管因颈部运动而移位,造成声门损伤。用于 NTI 的设备包括不同类型的导管、直接喉镜与视频喉镜以及纤维支气管镜。考虑到儿科解剖学,视频喉镜的优势受到质疑。对不同技术进行比较的研究有助于深入了解其疗效。确定儿科患者鼻气管导管的适当大小和深度仍是一项挑战。基于年龄、体重和身高的各种计算公式,包括基于深度标记的鼻气管插管建议,都已得到探讨。本综述全面概述了儿科患者的鼻气管插管,包括相关解剖、设备、临床判断和可能出现的并发症。
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引用次数: 0
Pain perception in 4-6-year-old children following intraoral dental injection with 26 and 31-gauge needles: a randomized controlled trial. 用 26 号和 31 号针头进行口腔内牙科注射后 4-6 岁儿童的疼痛感:随机对照试验。
Pub Date : 2024-04-01 Epub Date: 2024-03-28 DOI: 10.17245/jdapm.2024.24.2.101
Sneharaj N, Akhilesh Sharma, Madhusudhan Kempaiah Siddaiah, Priya Subramaniam

Background: Administering anesthesia in dentistry can be distressing for patients, especially those with dental fear and anxiety. Needle pain during local anesthesia is a common concern in intraoral procedures. This study aimed to compare pain perception in 4-6-year-old children following intraoral dental injections with 26- and 31-gauge needles.

Methods: Fifty healthy children were divided according to age into Group I (N = 25; 4-5 years) and Group II (N = 25; 5-6 years). Each group was further subdivided according to the needle gauge as follows: Group IA (26 gauge), Group IB (31 gauge), Group IIA (26 gauge), and Group IIB (31 gauge). Using a lottery method, the gauge of the needle to be used at the first visit for local anesthesia administration was selected. Children's reactions to pain were evaluated using a Modified Behavioral Pain Scale. Immediately after administration of local anesthesia, pain perception was evaluated using the Faces pain rating scale. In the subsequent visit, another needle gauge was used to administer local anesthesia, and the previously described evaluations were performed. At the third appointment, the child was shown both syringes and asked to choose one of the syringes they preferred, and the choice was noted.

Results: When local anesthesia was administered using a 31-gauge needle, pain perception was similar between the two groups. In group II, the children demonstrated significantly higher arm and leg movements (P = 0.001). However, the difference was significant in group I alone (P < 0.001).

Conclusion: Irrespective of age, anesthesia with a 31-gauge needle resulted in significantly lower pain perception than anesthesia with a 26-gauge needle.

背景:在牙科中实施麻醉可能会让患者感到痛苦,尤其是那些患有牙科恐惧和焦虑症的患者。局部麻醉时的针头疼痛是口腔内手术中常见的问题。本研究旨在比较 4-6 岁儿童在使用 26 号针头和 31 号针头进行口腔内牙科注射时的疼痛感:方法:50 名健康儿童按年龄分为第一组(25 人,4-5 岁)和第二组(25 人,5-6 岁)。每组又根据针号细分如下:IA 组(26 号针)、IB 组(31 号针)、IIA 组(26 号针)和 IIB 组(31 号针)。通过抽签的方式,选定首次就诊时使用的局部麻醉针的规格。使用改良行为疼痛量表评估儿童对疼痛的反应。实施局部麻醉后,立即使用 "面孔 "疼痛评分量表对疼痛感进行评估。在随后的就诊中,使用另一种针规进行局部麻醉,并进行之前所述的评估。在第三次就诊时,医生向患儿展示了两种注射器,要求患儿选择其中一种,并记录了患儿的选择:结果:使用 31 号针头进行局部麻醉时,两组患儿的疼痛感觉相似。在第二组中,儿童的手臂和腿部运动明显增加(P = 0.001)。然而,仅在第一组中,差异就很明显(P < 0.001):结论:无论年龄大小,使用 31 号针头进行麻醉的疼痛感明显低于使用 26 号针头进行麻醉的疼痛感。
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引用次数: 0
An innovative method of pilot balloon capping for submental intubation. 一种用于下颌插管的先导球囊封顶创新方法。
Pub Date : 2024-04-01 Epub Date: 2024-03-28 DOI: 10.17245/jdapm.2024.24.2.139
Molli Kiran, Sri Rama Ananta Nagabhushanam Padala, Preeti Preeti, Seema Seema, Koovakattil Akhil Kuttan
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引用次数: 0
Efficacy of sucrose application in minimizing pain perception related to dental injection in children aged 3 to 9 years: a randomized control trial. 应用蔗糖减轻 3 至 9 岁儿童牙科注射疼痛感的效果:随机对照试验。
Pub Date : 2024-04-01 Epub Date: 2024-03-28 DOI: 10.17245/jdapm.2024.24.2.109
Ishani Ratnaparkhi, Jasmin Winnier, Divya Shetty, Sanjana R Kodical, Reema Manoj, Shilpa S Naik

Background: Dental fear and anxiety are significant challenges in managing behavior in children. Oral administration of sucrose or sweet-tasting solutions has shown effectiveness in reducing procedural pain in infants and neonates. This study aimed to investigate whether pre-application of sucrose solution had an effect on minimizing pain perception during injection and to assess the potential impact of the child's age and sweet preference.

Methods: A randomized control clinical trial was conducted on 60 children aged 3-9 years requiring buccal infiltration injections. Following parental consent, demographic data of the children were recorded. Sweet preferences was assessed using a modified forced-choice test. Children were equally and randomly allocated into study (sucrose) and control groups using a lottery method. Sucrose solution or distilled water, respectively, was applied to the lateral surface of the tongue for 2 min. Topical anesthetic was applied at the site of injection, followed by local anesthesia administration. The children rinsed their mouths thrice with water immediately after anesthetic injection. A video was recorded during injection which was then scored by three blinded examiners on the Sound Eye Motor (SEM) scale. The children also self-evaluated using Wong-Baker Faces Pain Rating Scale (WBFPS).

Results: The mean SEM scores and WBFPS scores were analyzed using the Kruskall-Wallis test. The mean SEM score in the study group was 1.37 ± 0.61, compared to 3.17 ± 0.87 in the control group, showing a statistically significant difference (P < 0.001). Mean pain scores assessed by WBFPS in the study group were 0.60 ± 1.4, while in the control group, they were 6.27 ± 2.33, also showing a statistically significant difference (P < 0.001). Children with a sweet preference demonstrated a subjective reduction in pain perception.

Conclusion: Application of sucrose before dental injections in children helps to minimize pain upon injection across all age groups.

背景:牙科恐惧和焦虑是管理儿童行为的重大挑战。口服蔗糖或甜味溶液可有效减轻婴儿和新生儿的程序性疼痛。本研究旨在探究在注射过程中预先使用蔗糖溶液是否能有效减少疼痛感,并评估儿童的年龄和对甜味的偏好可能产生的影响:方法:对 60 名需要进行颊部浸润注射的 3-9 岁儿童进行了随机对照临床试验。在征得家长同意后,记录了儿童的人口统计学数据。采用改良的强迫选择测试评估儿童对甜食的偏好。采用抽签法将儿童平均随机分配到研究组(蔗糖)和对照组。将蔗糖溶液或蒸馏水分别涂抹在舌头外侧表面 2 分钟。在注射部位涂抹局部麻醉剂,然后进行局部麻醉。注射麻醉剂后,儿童立即用水漱口三次。注射过程被录制成视频,然后由三位盲人检查员根据声眼运动(SEM)量表进行评分。儿童还使用黄-贝克面痛量表(WBFPS)进行了自我评估:采用 Kruskall-Wallis 检验对 SEM 平均得分和 WBFPS 平均得分进行分析。研究组的平均 SEM 分数为 1.37 ± 0.61,而对照组为 3.17 ± 0.87,差异有统计学意义(P < 0.001)。研究组通过 WBFPS 评估的平均疼痛评分为 0.60 ± 1.4,而对照组为 6.27 ± 2.33,差异也有统计学意义(P < 0.001)。偏好甜食的儿童主观疼痛感有所减轻:结论:在儿童牙科注射前使用蔗糖有助于最大程度地减轻各年龄组儿童在注射时的疼痛。
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引用次数: 0
期刊
Journal of dental anesthesia and pain medicine
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