首页 > 最新文献

Bulletin of the Chemical Society of Japan最新文献

英文 中文
Brønsted Base-Catalyzed Reductive Deimination of α-Iminoketones Brønsted碱催化α-亚氨基酮还原脱氨反应
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-25 DOI: 10.1246/bcsj.20230125
Azusa Kondoh, Seitaro Inoue, Rihaku Ojima, M. Terada
{"title":"Brønsted Base-Catalyzed Reductive Deimination of α-Iminoketones","authors":"Azusa Kondoh, Seitaro Inoue, Rihaku Ojima, M. Terada","doi":"10.1246/bcsj.20230125","DOIUrl":"https://doi.org/10.1246/bcsj.20230125","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49355685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Affecting the Quality of Life of Parents Caring for Pediatric Patients with a Tracheostomy. 影响气管切开术患儿家长护理生活质量的因素。
IF 0.5 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-24 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1771345
Alper Koker, Nazan Ülgen Tekerek, Gonca Şahan Erbaşı Nalbant, Erdem Çebişli, Oguz Dursun

Objectives  This study aimed to evaluate factors affecting the quality of life (QOL) of parents of children who underwent placement of a tracheostomy while in the pediatric intensive care unit (PICU) through postdischarge use of a standardized questionnaire, Functional Status Scale (FSS) for patients, and WHOQoL-BREF (a QOL scale) for parents. Methods  The parents were initially contacted by telephone, postdischarge, during which the standardized questionnaire was completed. The functional status of the patients was evaluated using the FSS, and the QOL of parents was determined through use of the WHOQoL-BREF scale. Results  From 2011 to 2021, tracheostomy was performed in 119 PICU patients. Overall, 93 patients were excluded due to death in 66 (56%), decannulation in 24 (20%) and, 3 (2%) were not available for follow-up. The parents of 26 (22%) patients were available for follow-up and for which the standardized questionnaire FSS and WHOQoL-BREF QOL scales were completed. The mean FSS score of the patients was elevated at 17.84. In comparison, reduced mean scores were observed for parental physical health of 20.61, psychological health of 20.57, social health of 11.15, and environmental health of 29.00. As a result, a moderate ( r < 0.80), yet significant ( p ≤ 0.004) negative correlation was found between the FSS scores of patients and the physical, social relationships, environmental, and psychological health QOL scores of parents. Conclusion  This study is unique in that, to our knowledge, it is the first to compare parental QOL with the FSS of pediatric patients who have undergone a tracheostomy while hospitalized in the PICU. Our findings indicate that the parental QOL was reduced in four areas and correlates with an elevation in FSS score (indicating a greater functional disorder) of pediatric patients who had previously undergone a tracheostomy while hospitalized in the PICU.

目的本研究旨在通过标准化问卷、患者功能状态量表(FSS)和家长WHOQoL-BREF(生活质量量表)评估儿童重症监护病房(PICU)气管切开术患儿父母的生活质量(QOL)影响因素。方法出院后通过电话联系家长,并填写标准化问卷。采用FSS量表评估患者的功能状态,采用WHOQoL-BREF量表评估家长的生活质量。结果2011 - 2021年PICU患者气管切开术119例。总体而言,93例患者因66例(56%)死亡而被排除,24例(20%)被排除,3例(2%)无法随访。对26例(22%)患者的家长进行了随访,并完成了标准化问卷FSS和WHOQoL-BREF生活质量量表。患者FSS平均评分提高至17.84分。相比之下,父母身体健康平均得分为20.61分,心理健康平均得分为20.57分,社会健康平均得分为11.15分,环境健康平均得分为29.00分。结果显示,患者的FSS评分与父母的身体、社会关系、环境和心理健康生活质量评分呈中度(r < 0.80)但显著(p≤0.004)负相关。本研究的独特之处在于,据我们所知,它是第一个比较在PICU住院期间接受气管切开术的儿科患者的父母生活质量和FSS的研究。我们的研究结果表明,在PICU住院期间接受过气管切开术的儿科患者,父母的生活质量在四个方面降低,并与FSS评分升高(表明更大的功能障碍)相关。
{"title":"Factors Affecting the Quality of Life of Parents Caring for Pediatric Patients with a Tracheostomy.","authors":"Alper Koker, Nazan Ülgen Tekerek, Gonca Şahan Erbaşı Nalbant, Erdem Çebişli, Oguz Dursun","doi":"10.1055/s-0043-1771345","DOIUrl":"10.1055/s-0043-1771345","url":null,"abstract":"<p><p><b>Objectives</b>  This study aimed to evaluate factors affecting the quality of life (QOL) of parents of children who underwent placement of a tracheostomy while in the pediatric intensive care unit (PICU) through postdischarge use of a standardized questionnaire, Functional Status Scale (FSS) for patients, and WHOQoL-BREF (a QOL scale) for parents. <b>Methods</b>  The parents were initially contacted by telephone, postdischarge, during which the standardized questionnaire was completed. The functional status of the patients was evaluated using the FSS, and the QOL of parents was determined through use of the WHOQoL-BREF scale. <b>Results</b>  From 2011 to 2021, tracheostomy was performed in 119 PICU patients. Overall, 93 patients were excluded due to death in 66 (56%), decannulation in 24 (20%) and, 3 (2%) were not available for follow-up. The parents of 26 (22%) patients were available for follow-up and for which the standardized questionnaire FSS and WHOQoL-BREF QOL scales were completed. The mean FSS score of the patients was elevated at 17.84. In comparison, reduced mean scores were observed for parental physical health of 20.61, psychological health of 20.57, social health of 11.15, and environmental health of 29.00. As a result, a moderate ( <i>r</i> < 0.80), yet significant ( <i>p</i> ≤ 0.004) negative correlation was found between the FSS scores of patients and the physical, social relationships, environmental, and psychological health QOL scores of parents. <b>Conclusion</b>  This study is unique in that, to our knowledge, it is the first to compare parental QOL with the FSS of pediatric patients who have undergone a tracheostomy while hospitalized in the PICU. Our findings indicate that the parental QOL was reduced in four areas and correlates with an elevation in FSS score (indicating a greater functional disorder) of pediatric patients who had previously undergone a tracheostomy while hospitalized in the PICU.</p>","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":"65 1","pages":"330-336"},"PeriodicalIF":0.5,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88972101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catalytic Carbon Dioxide Fixation Reactions Based on Transition Metal Complexes and Their Systems 基于过渡金属配合物及其体系的催化二氧化碳固定反应
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-22 DOI: 10.1246/bcsj.20230133
N. Iwasawa
{"title":"Catalytic Carbon Dioxide Fixation Reactions Based on Transition Metal Complexes and Their Systems","authors":"N. Iwasawa","doi":"10.1246/bcsj.20230133","DOIUrl":"https://doi.org/10.1246/bcsj.20230133","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48007636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solvent-free mechanochemical synthesis of strongly luminescent Eu(III) hybrid materials using tetramethylammonium salts 四甲基铵盐无溶剂机械化学合成强发光Eu(III)杂化材料
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-22 DOI: 10.1246/bcsj.20230117
Ziying Li, Kazuki Nakamura, Norihisa Kobayashi
{"title":"Solvent-free mechanochemical synthesis of strongly luminescent Eu(III) hybrid materials using tetramethylammonium salts","authors":"Ziying Li, Kazuki Nakamura, Norihisa Kobayashi","doi":"10.1246/bcsj.20230117","DOIUrl":"https://doi.org/10.1246/bcsj.20230117","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49595419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colloidal Trehalose Nanoparticles for Sacrifice Template of Hollow Silica Nanosphere 用于中空二氧化硅纳米球牺牲模板的胶体海藻糖纳米颗粒
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-22 DOI: 10.1246/bcsj.20230097
H. Matsune, Ren Ikemizu, K. Shiomori, Emi Muraoka, Tsuyoshi Yamamoto, M. Kishida
{"title":"Colloidal Trehalose Nanoparticles for Sacrifice Template of Hollow Silica Nanosphere","authors":"H. Matsune, Ren Ikemizu, K. Shiomori, Emi Muraoka, Tsuyoshi Yamamoto, M. Kishida","doi":"10.1246/bcsj.20230097","DOIUrl":"https://doi.org/10.1246/bcsj.20230097","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44670128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supramolecular–Polymer Composite Hydrogels: from In Situ Network Observation to Functional Properties 超分子-聚合物复合水凝胶:从原位网络观察到功能特性
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-21 DOI: 10.1246/bcsj.20230129
Ryou Kubota
{"title":"Supramolecular–Polymer Composite Hydrogels: from In Situ Network Observation to Functional Properties","authors":"Ryou Kubota","doi":"10.1246/bcsj.20230129","DOIUrl":"https://doi.org/10.1246/bcsj.20230129","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45662133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Inhibition Effect on an Intracrystalline Reaction by a Crystal Lattice: Analyses of the Chemiluminescence Reaction of 9,10-Diphenylanthracene Endoperoxide Initiated by Heating of a Crystal Sample 晶格对晶内反应的抑制作用——晶体样品加热引发9,10-二苯基蒽内过氧化物化学发光反应的分析
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-19 DOI: 10.1246/bcsj.20230121
Norihisa Yamasaki, C. Matsuhashi, Hironaga Oyama, H. Uekusa, J. Morikawa, M. Ryu, Tetsuya Tsujii, N. Nakayama, S. Obata, Hitoshi Goto, S. Maki, T. Hirano
{"title":"An Inhibition Effect on an Intracrystalline Reaction by a Crystal Lattice: Analyses of the Chemiluminescence Reaction of 9,10-Diphenylanthracene Endoperoxide Initiated by Heating of a Crystal Sample","authors":"Norihisa Yamasaki, C. Matsuhashi, Hironaga Oyama, H. Uekusa, J. Morikawa, M. Ryu, Tetsuya Tsujii, N. Nakayama, S. Obata, Hitoshi Goto, S. Maki, T. Hirano","doi":"10.1246/bcsj.20230121","DOIUrl":"https://doi.org/10.1246/bcsj.20230121","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46495012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanopore sequencing of short dsDNA after elongation by combination of ligation and PEAR 结合结扎和PEAR的短dsDNA延伸后的纳米孔测序
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-19 DOI: 10.1246/bcsj.20230116
Bingxiao Cheng, K. Hu, Ziting Song, Ran An, Xingguo Liang
{"title":"Nanopore sequencing of short dsDNA after elongation by combination of ligation and PEAR","authors":"Bingxiao Cheng, K. Hu, Ziting Song, Ran An, Xingguo Liang","doi":"10.1246/bcsj.20230116","DOIUrl":"https://doi.org/10.1246/bcsj.20230116","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":"45 4","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41278310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-Isocyanate Polyurethane Synthesis by Polycondensation of Alkylene and Arylene Bis(fluoroalkyl) Bis(carbonate)s with Diamines 烷基烯和芳烯双(氟烷基)双(碳酸酯)与二胺缩聚合成非异氰酸酯聚氨酯
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-15 DOI: 10.1246/bcsj.20230066
Sasuga Hosokawa, A. Nagao, Yuka Hashimoto, Ayako Matsune, T. Okazoe, Chitoshi Suzuki, H. Wada, Toshifumi Kakiuchi, Akihiko Tsuda
{"title":"Non-Isocyanate Polyurethane Synthesis by Polycondensation of Alkylene and Arylene Bis(fluoroalkyl) Bis(carbonate)s with Diamines","authors":"Sasuga Hosokawa, A. Nagao, Yuka Hashimoto, Ayako Matsune, T. Okazoe, Chitoshi Suzuki, H. Wada, Toshifumi Kakiuchi, Akihiko Tsuda","doi":"10.1246/bcsj.20230066","DOIUrl":"https://doi.org/10.1246/bcsj.20230066","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44481704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facile Preparation of Near Infrared-Luminescent Protein Complexes with Conjugated Polymers Consisting of Boron Azobenzene Units 硼-偶氮苯单元共轭聚合物与近红外发光蛋白配合物的简易制备
IF 4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-07-15 DOI: 10.1246/bcsj.20230083
Dahye Yoo, Masashi Nakamura, Misato Kanjo, Masayuki Gon, Hiroyuki Watanabe, H. Kita, Kazuo Tanaka
{"title":"Facile Preparation of Near Infrared-Luminescent Protein Complexes with Conjugated Polymers Consisting of Boron Azobenzene Units","authors":"Dahye Yoo, Masashi Nakamura, Misato Kanjo, Masayuki Gon, Hiroyuki Watanabe, H. Kita, Kazuo Tanaka","doi":"10.1246/bcsj.20230083","DOIUrl":"https://doi.org/10.1246/bcsj.20230083","url":null,"abstract":"","PeriodicalId":9511,"journal":{"name":"Bulletin of the Chemical Society of Japan","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47143255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Bulletin of the Chemical Society of Japan
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1