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Cardiovascular Drugs and Therapy最新文献

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Success Rates, Complications, and Mortality with Laser Lead Extraction of Cardiovascular Implantable Electronic Devices. 激光铅拔出心血管植入式电子装置的成功率、并发症和死亡率。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-20 DOI: 10.1007/s10557-026-07868-5
Patrick T Lynch, Emily Y Xiao, Faiz M Baqai, Derrick A Draeger, Alexandra M Lewis, Mehdi Razavi, Nilesh Mathuria, Jie Cheng, John Seger, Abdi Rasekh, Mohammad Saeed, Mihail G Chelu
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引用次数: 0
Vps16 Attenuates Myocardial Ischemia/reperfusion Injury by Interacting with UVRAG and Activating Rab7. Vps16通过与UVRAG相互作用并激活Rab7减轻心肌缺血/再灌注损伤。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-19 DOI: 10.1007/s10557-026-07865-8
Yuanbin Li, Jinhao Zhou, Dan Wang, Xu Yan, Yiguo Ouyang, Wei Wang, Chenyao Zhu, Zhuang Chen
{"title":"Vps16 Attenuates Myocardial Ischemia/reperfusion Injury by Interacting with UVRAG and Activating Rab7.","authors":"Yuanbin Li, Jinhao Zhou, Dan Wang, Xu Yan, Yiguo Ouyang, Wei Wang, Chenyao Zhu, Zhuang Chen","doi":"10.1007/s10557-026-07865-8","DOIUrl":"https://doi.org/10.1007/s10557-026-07865-8","url":null,"abstract":"","PeriodicalId":9557,"journal":{"name":"Cardiovascular Drugs and Therapy","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MicroRNAs and Long Non-coding RNAs Associated With Sirtuin Pathways in Myocardial Ischemia/Reperfusion Injury. 心肌缺血/再灌注损伤中与Sirtuin通路相关的microrna和长链非编码rna。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-18 DOI: 10.1007/s10557-026-07860-z
Anna Nowak-Szwed, Ceren Eyileten, Zofia Wicik, Sara Ahmadova, Dirk von Lewinski, Harald Sourij, Marek Postula
{"title":"MicroRNAs and Long Non-coding RNAs Associated With Sirtuin Pathways in Myocardial Ischemia/Reperfusion Injury.","authors":"Anna Nowak-Szwed, Ceren Eyileten, Zofia Wicik, Sara Ahmadova, Dirk von Lewinski, Harald Sourij, Marek Postula","doi":"10.1007/s10557-026-07860-z","DOIUrl":"https://doi.org/10.1007/s10557-026-07860-z","url":null,"abstract":"","PeriodicalId":9557,"journal":{"name":"Cardiovascular Drugs and Therapy","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147479942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Nonlinear Relationship Between Serum Uric Acid and Cardiovascular Disease Risk: Mechanistic Insights and Clinical Implications. 血清尿酸与心血管疾病风险的非线性关系:机制见解和临床意义。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-16 DOI: 10.1007/s10557-026-07866-7
Chunyan Hou, Zhiwei Zheng, Xiaoqian Zheng, Menghua Liu, Shuling Xu, Rumeng Chen, Meihua Bao, Chunxia Huang, Sen Li
{"title":"The Nonlinear Relationship Between Serum Uric Acid and Cardiovascular Disease Risk: Mechanistic Insights and Clinical Implications.","authors":"Chunyan Hou, Zhiwei Zheng, Xiaoqian Zheng, Menghua Liu, Shuling Xu, Rumeng Chen, Meihua Bao, Chunxia Huang, Sen Li","doi":"10.1007/s10557-026-07866-7","DOIUrl":"https://doi.org/10.1007/s10557-026-07866-7","url":null,"abstract":"","PeriodicalId":9557,"journal":{"name":"Cardiovascular Drugs and Therapy","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147466851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
E3 Ubiquitin Ligase UBR5 Aggravates Cardiac Hypertrophy Via Inhibiting Nrf2/HO-1 Pathway. E3泛素连接酶UBR5通过抑制Nrf2/HO-1通路加重心肌肥厚。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-13 DOI: 10.1007/s10557-026-07852-z
Guofeng Zhu, Haiyang Fang, Congcong Xu, Kai Zhu, Tieqiu Huang, Wei Zhou, Min Huang
{"title":"E3 Ubiquitin Ligase UBR5 Aggravates Cardiac Hypertrophy Via Inhibiting Nrf2/HO-1 Pathway.","authors":"Guofeng Zhu, Haiyang Fang, Congcong Xu, Kai Zhu, Tieqiu Huang, Wei Zhou, Min Huang","doi":"10.1007/s10557-026-07852-z","DOIUrl":"https://doi.org/10.1007/s10557-026-07852-z","url":null,"abstract":"","PeriodicalId":9557,"journal":{"name":"Cardiovascular Drugs and Therapy","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147455312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening of Anti-atherosclerosis Drugs Based on the Apolipoprotein apoeb Gene Knockout Zebrafish Model. 基于载脂蛋白apoeb基因敲除斑马鱼模型的抗动脉粥样硬化药物筛选。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-10 DOI: 10.1007/s10557-026-07847-w
Haoyan Wang, Jiufeng Yin, Hui Wang, Mingkai Li, Xinyi Zhang, Feng Zhao, Wenqing Yang
{"title":"Screening of Anti-atherosclerosis Drugs Based on the Apolipoprotein apoeb Gene Knockout Zebrafish Model.","authors":"Haoyan Wang, Jiufeng Yin, Hui Wang, Mingkai Li, Xinyi Zhang, Feng Zhao, Wenqing Yang","doi":"10.1007/s10557-026-07847-w","DOIUrl":"https://doi.org/10.1007/s10557-026-07847-w","url":null,"abstract":"","PeriodicalId":9557,"journal":{"name":"Cardiovascular Drugs and Therapy","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally Invasive Trans-atrial Mitral Valve Replacement Using a Balloon-expandable Transcatheter Valve in the Setting of Severe Mitral Annular Calcification. 微创经心房二尖瓣置换术在严重二尖瓣环钙化中的应用。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-09 DOI: 10.1007/s10557-025-07804-z
Syed B Peer, Prakash Jayanthi, Zachary Gray, Aladdein Mattar, Guilherme Silva, Srikanth Koneru, Kenneth Liao
{"title":"Minimally Invasive Trans-atrial Mitral Valve Replacement Using a Balloon-expandable Transcatheter Valve in the Setting of Severe Mitral Annular Calcification.","authors":"Syed B Peer, Prakash Jayanthi, Zachary Gray, Aladdein Mattar, Guilherme Silva, Srikanth Koneru, Kenneth Liao","doi":"10.1007/s10557-025-07804-z","DOIUrl":"https://doi.org/10.1007/s10557-025-07804-z","url":null,"abstract":"","PeriodicalId":9557,"journal":{"name":"Cardiovascular Drugs and Therapy","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147389590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond Patient Factors: Are we Missing the Surgical Context in Comparing Tirzepatide and Semaglutide Post-CABG? 超越患者因素:我们在比较替西帕肽和西马鲁肽cabg后是否忽略了手术背景?
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-09 DOI: 10.1007/s10557-026-07832-3
Mingyue Chen, Yan Han, Fenxiang Zhang
{"title":"Beyond Patient Factors: Are we Missing the Surgical Context in Comparing Tirzepatide and Semaglutide Post-CABG?","authors":"Mingyue Chen, Yan Han, Fenxiang Zhang","doi":"10.1007/s10557-026-07832-3","DOIUrl":"https://doi.org/10.1007/s10557-026-07832-3","url":null,"abstract":"","PeriodicalId":9557,"journal":{"name":"Cardiovascular Drugs and Therapy","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147389597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Hypothesis-generating to Decision-grade: Making Finerenone-spironolactone Comparisons in HFpEF Globally Implementable. 从假设生成到决策级别:使芬内酮-螺内酯在HFpEF中的比较在全球范围内实现。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-09 DOI: 10.1007/s10557-026-07856-9
M Vijayasimha, M Srikanth, Gurjeet Singh
{"title":"From Hypothesis-generating to Decision-grade: Making Finerenone-spironolactone Comparisons in HFpEF Globally Implementable.","authors":"M Vijayasimha, M Srikanth, Gurjeet Singh","doi":"10.1007/s10557-026-07856-9","DOIUrl":"https://doi.org/10.1007/s10557-026-07856-9","url":null,"abstract":"","PeriodicalId":9557,"journal":{"name":"Cardiovascular Drugs and Therapy","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147389602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Ultrasound in Cardiovascular Medicine: Applications of Low-intensity Pulsed Ultrasound and Ultrasound-targeted Microbubble Destruction. 超声治疗在心血管医学中的应用:低强度脉冲超声和超声靶向微泡破坏。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-03-07 DOI: 10.1007/s10557-026-07864-9
Yucong Shi, Yongqing Ye, Shanshan Chang, Dongxu Lu, Yinzhu Chu

Cardiovascular disease (CVD) represents a significant global health challenge, with its high incidence and mortality rates placing a substantial burden on both patients and society. Although conventional therapies have achieved certain results, they continue to face considerable limitations. In recent years, therapeutic ultrasound has emerged as a promising medical technology, offering notable potential in the treatment of CVD owing to its non-invasiveness, safety, and targeting precision. Low-intensity pulsed ultrasound (LIPUS), a form of therapeutic ultrasound, uses pulsed, low-intensity, moderate-frequency acoustic waves to produce biological effects. This modality minimizes thermal impact while enhancing mechanical interactions. Another well-regarded technique is ultrasound-targeted microbubble destruction (UTMD), an innovative gene delivery system characterized by safety, reliable targeting, and high personalization. In clinical practice for CVD, both LIPUS and UTMD exhibit distinct advantages. This review examines the current landscape of CVD and discusses the potential and future applications of LIPUS and UTMD in their management.

心血管疾病(CVD)是一项重大的全球健康挑战,其高发病率和死亡率给患者和社会带来沉重负担。虽然传统疗法取得了一定的效果,但它们仍然面临相当大的局限性。近年来,超声治疗已成为一项很有前途的医疗技术,由于其无创性、安全性和靶向精确性,在心血管疾病的治疗中具有显着的潜力。低强度脉冲超声(LIPUS)是一种治疗性超声,利用脉冲、低强度、中频声波产生生物效应。这种方式最大限度地减少了热冲击,同时增强了机械相互作用。另一种备受推崇的技术是超声靶向微泡破坏(UTMD),这是一种创新的基因传递系统,具有安全、可靠的靶向性和高度个性化的特点。在心血管疾病的临床实践中,LIPUS和UTMD都表现出明显的优势。本文综述了心血管疾病的现状,并讨论了LIPUS和UTMD在心血管疾病治疗中的潜在和未来应用。
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引用次数: 0
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Cardiovascular Drugs and Therapy
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