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Metabolic Syndrome and Risk of Gastric Cancer: A Meta-analysis 代谢综合征与胃癌风险的meta分析
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.0957
Liangyu Tong, Li Huajie, DA Mingxu
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引用次数: 0
Advance in Therapeutic Targets of Intrahepatic Cholangiocarcinoma 肝内胆管癌治疗靶点研究进展
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.1248
Lin Jian, W. Haibo, Shen Feng
{"title":"Advance in Therapeutic Targets of Intrahepatic Cholangiocarcinoma","authors":"Lin Jian, W. Haibo, Shen Feng","doi":"10.3971/J.ISSN.1000-8578.2021.20.1248","DOIUrl":"https://doi.org/10.3971/J.ISSN.1000-8578.2021.20.1248","url":null,"abstract":"","PeriodicalId":9579,"journal":{"name":"肿瘤防治研究","volume":"19 1","pages":"224-228"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84861730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress on Relation Between Shift Work and Ovarian Cancer 轮班工作与卵巢癌关系的研究进展
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.0675
Gao Chang, Zhang Shuang, Wen Zhaoyan, Gong Tingting, Zhao Yuhong, Wu Qijun
{"title":"Research Progress on Relation Between Shift Work and Ovarian Cancer","authors":"Gao Chang, Zhang Shuang, Wen Zhaoyan, Gong Tingting, Zhao Yuhong, Wu Qijun","doi":"10.3971/J.ISSN.1000-8578.2021.20.0675","DOIUrl":"https://doi.org/10.3971/J.ISSN.1000-8578.2021.20.0675","url":null,"abstract":"","PeriodicalId":9579,"journal":{"name":"肿瘤防治研究","volume":"21 1","pages":"293-298"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80977003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinicopathological Characteristics and Prognosis of Borrmann Type IV Gastric Cancer Borrmann IV型胃癌的临床病理特征及预后分析
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.0770
Ding Ping’an, Yan Peigang, Tian Yuan, Li Yecheng, Guo Honghai, Liu Yang, Z. Zhidong, W. Dong, Li Yong, Zhao Qun
{"title":"Clinicopathological Characteristics and Prognosis of Borrmann Type IV Gastric Cancer","authors":"Ding Ping’an, Yan Peigang, Tian Yuan, Li Yecheng, Guo Honghai, Liu Yang, Z. Zhidong, W. Dong, Li Yong, Zhao Qun","doi":"10.3971/J.ISSN.1000-8578.2021.20.0770","DOIUrl":"https://doi.org/10.3971/J.ISSN.1000-8578.2021.20.0770","url":null,"abstract":"","PeriodicalId":9579,"journal":{"name":"肿瘤防治研究","volume":"34 1","pages":"261-267"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89250420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progress in One-carbon Metabolism and Tumor Therapy 单碳代谢与肿瘤治疗进展
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.0420
Chai Dongqi, W. Weixing
{"title":"Progress in One-carbon Metabolism and Tumor Therapy","authors":"Chai Dongqi, W. Weixing","doi":"10.3971/J.ISSN.1000-8578.2021.20.0420","DOIUrl":"https://doi.org/10.3971/J.ISSN.1000-8578.2021.20.0420","url":null,"abstract":"","PeriodicalId":9579,"journal":{"name":"肿瘤防治研究","volume":"2 1","pages":"288-292"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83433512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bibliometric Analysis of Global Research on Colorectal Cancer Based on SCI-E 基于SCI-E的全球结直肠癌研究文献计量学分析
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.1475
Xu Zhiyong, Wei Shaozhong
{"title":"Bibliometric Analysis of Global Research on Colorectal Cancer Based on SCI-E","authors":"Xu Zhiyong, Wei Shaozhong","doi":"10.3971/J.ISSN.1000-8578.2021.20.1475","DOIUrl":"https://doi.org/10.3971/J.ISSN.1000-8578.2021.20.1475","url":null,"abstract":"","PeriodicalId":9579,"journal":{"name":"肿瘤防治研究","volume":"46 5 1","pages":"274-280"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77310602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
沉默LncRNA WT1-AS对三阴性乳腺癌细胞MDA-MB-231侵袭和迁移的影响 沉默LncRNA WT1-AS对三阴性乳腺癌细胞MDA-MB-231侵袭和迁移的影响
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.0744
舒家武, Shu Jiawu, 李熙君, Liu Xijun, 朱力勤, Zhu Liqin, 王燕燕, Wang Yan-yan
目的探讨LncRNA WT1-AS对三阴性乳腺癌细胞MDA-MB-231侵袭和迁移的影响。 方法qRT-PCR检测WT1-AS在三阴性乳腺癌细胞中的表达及基因沉默的效率；Transwell实验检测WT1-AS对MDA-MB-231细胞侵袭能力的影响；划痕实验检测WT1-AS对MDA-MB-231细胞迁移能力的影响；Western blot检测WT1-AS对MDA-MB-231细胞E-cadherin、N-cadherin、Vimentin和Snail表达的影响。 结果与正常乳腺上皮细胞相比，WT1-AS在三阴性乳腺癌细胞MDA-MB-231、MDA-MB-453、MDA-MB-468中的表达量明显上调；沉默WT1-AS后，MDA-MB-231细胞侵袭和迁移能力明显降低，且E-cadherin表达明显上调，N-cadherin、Vimentin和Snail表达量显著下调。 结论WT1-AS可以通过调控EMT促进三阴性乳腺癌细胞MDA-MB-231的侵袭与迁移能力。
目的探讨LncRNA WT1-AS对三阴性乳腺癌细胞MDA-MB-231侵袭和迁移的影响。 方法qRT-PCR检测WT1-AS在三阴性乳腺癌细胞中的表达及基因沉默的效率；Transwell实验检测WT1-AS对MDA-MB-231细胞侵袭能力的影响；划痕实验检测WT1-AS对MDA-MB-231细胞迁移能力的影响；Western blot检测WT1-AS对MDA-MB-231细胞E-cadherin、N-cadherin、Vimentin和Snail表达的影响。 结果与正常乳腺上皮细胞相比，WT1-AS在三阴性乳腺癌细胞MDA-MB-231、MDA-MB-453、MDA-MB-468中的表达量明显上调；沉默WT1-AS后，MDA-MB-231细胞侵袭和迁移能力明显降低，且E-cadherin表达明显上调，N-cadherin、Vimentin和Snail表达量显著下调。 结论WT1-AS可以通过调控EMT促进三阴性乳腺癌细胞MDA-MB-231的侵袭与迁移能力。
{"title":"沉默LncRNA WT1-AS对三阴性乳腺癌细胞MDA-MB-231侵袭和迁移的影响","authors":"舒家武, Shu Jiawu, 李熙君, Liu Xijun, 朱力勤, Zhu Liqin, 王燕燕, Wang Yan-yan","doi":"10.3971/J.ISSN.1000-8578.2021.20.0744","DOIUrl":"https://doi.org/10.3971/J.ISSN.1000-8578.2021.20.0744","url":null,"abstract":"目的探讨LncRNA WT1-AS对三阴性乳腺癌细胞MDA-MB-231侵袭和迁移的影响。 方法qRT-PCR检测WT1-AS在三阴性乳腺癌细胞中的表达及基因沉默的效率；Transwell实验检测WT1-AS对MDA-MB-231细胞侵袭能力的影响；划痕实验检测WT1-AS对MDA-MB-231细胞迁移能力的影响；Western blot检测WT1-AS对MDA-MB-231细胞E-cadherin、N-cadherin、Vimentin和Snail表达的影响。 结果与正常乳腺上皮细胞相比，WT1-AS在三阴性乳腺癌细胞MDA-MB-231、MDA-MB-453、MDA-MB-468中的表达量明显上调；沉默WT1-AS后，MDA-MB-231细胞侵袭和迁移能力明显降低，且E-cadherin表达明显上调，N-cadherin、Vimentin和Snail表达量显著下调。 结论WT1-AS可以通过调控EMT促进三阴性乳腺癌细胞MDA-MB-231的侵袭与迁移能力。","PeriodicalId":9579,"journal":{"name":"肿瘤防治研究","volume":"17 1","pages":"244-247"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74648847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress of Immune Checkpoint Therapy on Colorectal Cancer 免疫检查点治疗结直肠癌的研究进展
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.1060
C. Qihua, Xu Yanbo, Xu Dong
{"title":"Research Progress of Immune Checkpoint Therapy on Colorectal Cancer","authors":"C. Qihua, Xu Yanbo, Xu Dong","doi":"10.3971/J.ISSN.1000-8578.2021.20.1060","DOIUrl":"https://doi.org/10.3971/J.ISSN.1000-8578.2021.20.1060","url":null,"abstract":"","PeriodicalId":9579,"journal":{"name":"肿瘤防治研究","volume":"939 1","pages":"229-233"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85557655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
比卡鲁胺对乳腺癌细胞株MDA-MB-453的作用机制及与依维莫司联用的效果评估 比卡鲁胺对乳腺癌细胞株MDA-MB-453的作用机制及与依维莫司联用的效果评估
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.0819
张玉琴, Zhang Yu-qin, 陆云飞, Luo Yunfei, 张海添, Zhang Haitian
目的探讨比卡鲁胺对雄激素受体（AR）阳性乳腺癌细胞侵袭迁移能力的影响及相关作用机制，以及mTOR抑制剂依维莫司联合比卡鲁胺对MDA-MB-453细胞株增殖作用的影响。 方法Western blot方法检测比卡鲁胺作用前后乳腺癌细胞株mTOR、p-mTOR和p-S6表达的变化，Transwell迁移侵袭实验检测比卡鲁胺处理前后细胞活性的变化，MTT法检测依维莫司联合比卡鲁胺对MDA-MB-453乳腺癌细胞株增殖作用的影响，通过金正均法计算Q值，评估两药联用对乳腺癌细胞株MDA-MB-453抑制作用的效果。 结果比卡鲁胺作用6天后，MDA-MB-453细胞中mTOR、p-mTOR和p-S6的表达明显降低（Ρ =0.034, 0.05, 0.03），MDA-MB-453细胞的迁移侵袭能力较用药前受到明显抑制（迁移：t =4.88, Ρ =0.001；侵袭：t =2.684, Ρ =0.028）。比卡鲁胺联合依维莫司作用后，MDA-MB-453细胞株增殖受到抑制，各浓度下Q值均大于1.15。 结论比卡鲁胺能抑制MDA-MB-453乳腺癌细胞株的侵袭迁移，其抑制效果受AR的表达量影响。比卡鲁胺联合依维莫司可以协同抑制AR阳性乳腺癌细胞的增殖。
目的探讨比卡鲁胺对雄激素受体（AR）阳性乳腺癌细胞侵袭迁移能力的影响及相关作用机制，以及mTOR抑制剂依维莫司联合比卡鲁胺对MDA-MB-453细胞株增殖作用的影响。 方法Western blot方法检测比卡鲁胺作用前后乳腺癌细胞株mTOR、p-mTOR和p-S6表达的变化，Transwell迁移侵袭实验检测比卡鲁胺处理前后细胞活性的变化，MTT法检测依维莫司联合比卡鲁胺对MDA-MB-453乳腺癌细胞株增殖作用的影响，通过金正均法计算Q值，评估两药联用对乳腺癌细胞株MDA-MB-453抑制作用的效果。 结果比卡鲁胺作用6天后，MDA-MB-453细胞中mTOR、p-mTOR和p-S6的表达明显降低（Ρ =0.034, 0.05, 0.03），MDA-MB-453细胞的迁移侵袭能力较用药前受到明显抑制（迁移：t =4.88, Ρ =0.001；侵袭：t =2.684, Ρ =0.028）。比卡鲁胺联合依维莫司作用后，MDA-MB-453细胞株增殖受到抑制，各浓度下Q值均大于1.15。 结论比卡鲁胺能抑制MDA-MB-453乳腺癌细胞株的侵袭迁移，其抑制效果受AR的表达量影响。比卡鲁胺联合依维莫司可以协同抑制AR阳性乳腺癌细胞的增殖。
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引用次数: 0
Expression of LncRNA DLEU1 in Esophageal Squamous Cell Carcinoma and Its Effect on Proliferation and Migration of ESCC Cells LncRNA DLEU1在食管鳞状细胞癌中的表达及其对ESCC细胞增殖和迁移的影响
Q4 Medicine
肿瘤防治研究
Pub Date : 2021-03-23 DOI: 10.3971/J.ISSN.1000-8578.2021.20.0749
Duan Yuqing, Yu Wang, Wang Xuexiao, L. Lihua
{"title":"Expression of LncRNA DLEU1 in Esophageal Squamous Cell Carcinoma and Its Effect on Proliferation and Migration of ESCC Cells","authors":"Duan Yuqing, Yu Wang, Wang Xuexiao, L. Lihua","doi":"10.3971/J.ISSN.1000-8578.2021.20.0749","DOIUrl":"https://doi.org/10.3971/J.ISSN.1000-8578.2021.20.0749","url":null,"abstract":"","PeriodicalId":9579,"journal":{"name":"肿瘤防治研究","volume":"36 1","pages":"255-260"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87926396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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