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Cancer treatment reports最新文献

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Phase II study of isotretinoin in the treatment of advanced non-small cell lung cancer. 异维甲酸治疗晚期非小细胞肺癌的II期研究。
Cancer treatment reports
Pub Date : 1987-11-01
S M Grunberg, L M Itri
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引用次数: 0
Phase II study of spirohydantoin mustard for the treatment of recurrent malignant gliomas. 螺旋藻毒素芥治疗复发性恶性胶质瘤的II期研究。
Cancer treatment reports
Pub Date : 1987-11-01
M Prados, L Rodriguez, M Seager, P Silver, V Levin
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引用次数: 0
Phase II study of mitoxantrone in untreated and previously minimally treated patients with metastatic soft tissue sarcomas. 米托蒽醌在未治疗和先前最低限度治疗的转移性软组织肉瘤患者中的II期研究。
Cancer treatment reports
Pub Date : 1987-11-01
I Quirt, E Eisenhauer, V Bramwell, M Knowling, C Grafton, W Hirte, M Cripps, A Maksymiuk
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引用次数: 0
Continuous-infusion amsacrine in patients with refractory acute myelogenous leukemia. 持续输注amsacrine治疗难治性急性髓性白血病。
Cancer treatment reports
Pub Date : 1987-11-01
E H Estey, M J Keating, K B McCredie, E J Freireich
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引用次数: 0
Preliminary report on the treatment of esophageal cancer by intraluminal microwave hyperthermia and chemotherapy. 腔内微波热疗联合化疗治疗食管癌的初步报道。
Cancer treatment reports
Pub Date : 1987-11-01
D J Li, B S Hou

Thirty-two cases of esophageal cancer were treated with thermochemotherapy from August 1984 to June 1985. A combination of bleomycin (20 mg per session iv) and cisplatin (0.5-0.9 mg/kg per session as low dose and 1.0-2.0 mg/kg per session as high dose), or of bleomycin, cisplatin (high dose), and cyclophosphamide (400-600 mg per session) were the treatment regimens. A 915-MHz microwave applicator was inserted into the lumen of the esophagus for heating. The temperature at normal adjacent tissue to the cancer was at 43-44 degrees C, while the temperature of the cancer was at 45 degrees C-50 degrees C. Chemotherapy and hyperthermia were administered simultaneously, once a week for six to eight sessions. The response rate in the low-dose group was 36.4% (four of 11) and 81% (17 of 21) in the high-dose group. The complete response rate in the low-dose group was zero of 11 patients, with 38.1% (eight of 21) in the latter group. The relationship between power output and tumor response is also discussed.

本文对1984年8月~ 1985年6月食管癌32例进行热化疗治疗。治疗方案为博来霉素(每次20毫克)和顺铂(每次低剂量0.5-0.9毫克/千克，每次高剂量1.0-2.0毫克/千克)，或博来霉素、顺铂(每次高剂量)和环磷酰胺(每次400-600毫克)联合使用。将915 mhz微波涂抹器插入食管管腔加热。癌旁正常组织的温度为43-44摄氏度，而癌旁组织的温度为45 -50摄氏度，化疗和热疗同时进行，每周一次，持续6至8次。低剂量组有效率为36.4%(4 / 11)，高剂量组有效率为81%(17 / 21)。低剂量组11例患者的完全缓解率为零，低剂量组21例患者的完全缓解率为38.1%(8例)。文中还讨论了功率输出与肿瘤反应之间的关系。
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引用次数: 0
Continuous Sc infusion of metoclopramide for treatment of narcotic bowel syndrome. 甲氧氯普胺连续输注治疗麻醉性肠综合征。
Cancer treatment reports
Pub Date : 1987-11-01
E Bruera, C Brenneis, M Michaud, N MacDonald
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引用次数: 0
Severe and fatal toxic effects observed in treatment with high- and low-dose leucovorin plus 5-fluorouracil for colorectal carcinoma. 高剂量和低剂量亚叶酸钙加5-氟尿嘧啶治疗结直肠癌观察到严重和致命的毒性作用。
Cancer treatment reports
Pub Date : 1987-11-01
J L Grem, D D Shoemaker, N J Petrelli, H O Douglass
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引用次数: 0
Chemotherapy of adult soft tissue sarcoma with combination of doxorubicin and methotrexate. 阿霉素联合甲氨蝶呤治疗成人软组织肉瘤的疗效观察。
Cancer treatment reports
Pub Date : 1987-11-01
P Presgrave, R L Woods, M H Tattersall, A S Coates, J A Levi, R M Fox, D Hedley

Thirty-six adult patients with measurable advanced soft tissue sarcoma were treated with a combination of doxorubicin (70 mg/m2) and methotrexate (50 mg/m2) iv every 21 days. Partial remission was seen in ten of 33 evaluable patients (30%). Median duration of remission was 23 weeks, and median survival was 42 weeks. Bone marrow toxicity was the main toxic effect; 23% of the patients had a nadir leukocyte count less than 2.0 X 10(9)/L during therapy. These results do not suggest any therapeutic advantage in adding methotrexate to doxorubicin in this context.

36例可测量的晚期软组织肉瘤成年患者每21天联合使用阿霉素(70mg /m2)和甲氨蝶呤(50mg /m2) iv。33例可评估患者中有10例部分缓解(30%)。中位缓解持续时间为23周，中位生存期为42周。主要毒性作用为骨髓毒性;23%的患者在治疗期间最低白细胞计数低于2.0 × 10(9)/L。这些结果并不表明在这种情况下，在阿霉素中加入甲氨蝶呤有任何治疗优势。
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引用次数: 0
Phase II trial of prednimustine as first-line chemotherapy in patients with advanced breast cancer. prednimustine作为晚期乳腺癌患者一线化疗的II期试验。
Cancer treatment reports
Pub Date : 1987-11-01
E M Rankin, C Harvey, R K Knight, R D Rubens
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引用次数: 0
Ifosfamide plus 5-fluorouracil for treatment of adenocarcinoma of the pancreas. 异环磷酰胺加5-氟尿嘧啶治疗胰腺腺癌。
Cancer treatment reports
Pub Date : 1987-11-01
P J Loehrer, S D Williams, C R Nichols
{"title":"Ifosfamide plus 5-fluorouracil for treatment of adenocarcinoma of the pancreas.","authors":"P J Loehrer,&nbsp;S D Williams,&nbsp;C R Nichols","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9581,"journal":{"name":"Cancer treatment reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1987-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14251191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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