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Iatrogenic fetal goiter. Conservative management and spontaneous resolution 医源性胎儿甲状腺肿。保守管理和自发解决
IF 0.1 Pub Date : 2020-11-05 DOI: 10.1515/CRPM-2019-0074
M. A. D. L. Rosa, O. Aedo, R. Garzón, A. I. P. Pérez, J. Luque
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引用次数: 1
Survival of both twins in a pregnancy complicated by pre-viable cord prolapse at 21 weeks of gestation 在怀孕21周时,双胞胎因脐带脱垂并发症的存活情况
IF 0.1 Pub Date : 2020-04-01 DOI: 10.1515/CRPM-2019-0060
Alnoman Abdullah, A. Ghazi, BrownD. Richard
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引用次数: 1
Ultrasound diagnosis of myelomeningocele: the role of 3D ultrasonography in determining surficial status of the pathological lesion 脊髓脊膜膨出的超声诊断:三维超声在确定病理病变表面状态中的作用
IF 0.1 Pub Date : 2020-01-01 DOI: 10.1515/crpm-2018-0065
A. Kurasaki, J. Hasegawa, C. Homma, A. Miura, H. Kondo, N. Suzuki
Abstract Objectives Spina bifida manifests in various forms, and the clinical imaging findings depend on the level of the vertebral defect. It is difficult to predict the severity of the neurological symptoms and the degree of urgency of early treatment antenatally. Case presentation In the present case report of fetal myelomeningocele (MMC), three-dimensional (3D) ultrasound showed accurate findings of fetal back surficial skin and tissue defect. The neonatologist and surgeons were able to decide upon appropriate treatment strategies on the basis of these findings. Conclusions 3D ultrasound helps provide information to neonatologists and neurosurgeons about the initial treatment and illustrates the physical appearance of the disease for the parents of the unborn child.
摘要目的脊柱裂表现形式多样,临床影像学表现与椎体缺损程度有关。很难预测神经症状的严重程度和产前早期治疗的紧急程度。本病例报告胎儿脊髓脊膜膨出(MMC),三维(3D)超声显示胎儿背部表面皮肤和组织缺损的准确结果。新生儿学家和外科医生能够根据这些发现决定适当的治疗策略。结论三维超声有助于为新生儿医生和神经外科医生提供有关初始治疗的信息,并为未出生婴儿的父母说明疾病的物理外观。
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引用次数: 0
Monoamniotic twins pregnancy complicated by a fetal congenital heart defect – a challenge for perinatal decisions 单羊膜双胞胎妊娠合并胎儿先天性心脏缺陷-围产期决定的挑战
IF 0.1 Pub Date : 2020-01-01 DOI: 10.1515/crpm-2020-0022
M. Pasieczna, Joanna Kuran-Ohde, A. Kajdy, D. Filipecka-Tyczka, Natalia Świątek, J. Szymkiewicz-Dangel
Abstract Objectives To analyze pregnancy management and postnatal follow-up in monochorionic monoamniotic (MCMA) pregnancies complicated by a congenital heart defect (CHD) in one twin and to compare the results with current recommendations concerning time and mode of delivery in MCMA pregnancies. Cases presentation Perinatal medical records of five pairs of monoamniotic twins referred to Fetal Cardiology Department were analyzed. 5 out of 23 MCMA pregnancies (21.7%) were complicated by CHD in one fetus. Cesarean section (CS) was performed between 32 and 35 weeks of gestation (WoG). 9 out of 10 neonates had respiratory failure, including all patients with CHD. Twins without congenital abnormalities spent median 21 days (range 10–40 days) in neonatal units. Patients with CHD were transferred to cardiology departments on average 6th day of life. All were operated on later than term-born neonates, 4 out of 5 required stage surgery and their median stay in the hospital was 75 days (range 48–106 days). Conclusions According to current recommendations, delivery in MCMA pregnancies should be scheduled at 32–34 weeks. In cases complicated by CHD in one twin, such early delivery complicates surgical treatment and may affect the final outcome. Low body weight and respiratory disorders increase the risk of complications in the perioperative period and prolong hospitalization.
摘要目的分析单绒毛膜单羊膜(MCMA)妊娠合并先天性心脏缺陷(CHD)的妊娠管理和产后随访,并将结果与目前关于MCMA妊娠分娩时间和方式的建议进行比较。分析了5对转至胎儿心脏科的单羊膜双胞胎的围产期医疗记录。23例MCMA妊娠中有5例(21.7%)合并1例胎儿冠心病。在妊娠32 ~ 35周(WoG)行剖宫产术(CS)。10个新生儿中有9个呼吸衰竭,包括所有冠心病患者。没有先天性异常的双胞胎在新生儿病房中位数为21天(范围为10-40天)。冠心病患者平均在出生后第6天转到心内科。所有患者均为晚于足月出生的新生儿,5例中有4例需要分期手术,住院时间中位数为75天(48-106天)。结论根据目前的建议,MCMA妊娠的分娩应安排在32-34周。如果双胞胎中有一人并发冠心病,这种早产会使手术治疗复杂化,并可能影响最终结果。低体重和呼吸系统疾病增加围手术期并发症的发生风险,延长住院时间。
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引用次数: 1
Transmission of SARS-CoV-2 to premature twins from an asymptomatic mother 无症状母亲对早产双胞胎的SARS-CoV-2传播
IF 0.1 Pub Date : 2020-01-01 DOI: 10.1515/crpm-2020-0064
P. Gaunt, I. Ahmed, R. Geethanath, M. Abu-Harb, C. Onwuneme
Abstract Objectives The incidence of vertically transmitted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be higher than published. We feel that cases of SARS-CoV-2 vertical transmission are under-reported. Case presentation We report a case of SARS-CoV-2 in premature monochorionic monoamniotic twins born by caesarean section to an asymptomatic SARS-CoV-2 positive mother. Conclusions This case supports the potential for intrauterine transmission of SARS-CoV-2 as previously reported. The incidence of SARS-CoV-2 vertical transmission from reported cases is low; however this may be due to the difficulty disproving horizontal transmission or under-reporting of cases.
摘要目的垂直传播的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)的发病率可能高于公布的发病率。我们认为SARS-CoV-2垂直传播病例报告不足。我们报告一例无症状的SARS-CoV-2阳性母亲剖宫产的单绒毛膜单羊膜早产儿SARS-CoV-2病例。结论本病例支持先前报道的SARS-CoV-2宫内传播的可能性。报告病例中SARS-CoV-2垂直传播的发生率低;然而,这可能是由于难以反驳横向传播或病例报告不足。
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引用次数: 0
Neonatal hypertension caused by left-to-right shunt flow through a patent ductus arteriosus in a premature infant 早产儿动脉导管未闭左向右分流引起的新生儿高血压
IF 0.1 Pub Date : 2020-01-01 DOI: 10.1515/crpm-2020-0007
Sung-Ha Kim, Eujin Park, S. Hwang, T. Sung
Abstract Objectives Though it is rare and challenging to study, neonatal hypertension (HTN) has been explored and studied by many pediatricians. There were some causes reported in preterm infants such as renal diseases and bronchopulmonary dysplasia. Case presentation We report a premature female infant who was born at a gestational age of 25 + 6 weeks and developed systemic hypertension on the day of a gestation age of 30 + 3 weeks. This case had a rare cause which involved high-normal serum aldosterone level that could possibly indicate hyperaldosteronism and over-stimulation of renin–angiotensin–aldosterone system (RAAS). We believe elevation of serum aldosterone was caused by a left-to-right shunt flow through a patent ductus arteriosus. Hypertension due to a patent ductus arteriosus sounds like a paradox. However, in our case, the shunt flow was shown to be a possible cause of the systemic hypertension. Surgical closure of the shunt was done and the hypertension resolved. We evaluated serum aldosterone levels and plasma renin activities both, before and after the closure to look for a possible cause. Conclusions Neonatologist often treats systemic hypertensive infants considering possible causes in order to prevent hypertensive crisis. Our case shows that possibility of hyperaldosteronism and (RAAS) over-stimulation should be considered as causes in case of severe systemic hypertension in preterm infants with large left-to-right shunt flows.
【摘要】目的新生儿高血压(HTN)是一种罕见且具有挑战性的疾病,许多儿科医生对其进行了探索和研究。有一些原因报道的早产儿,如肾脏疾病和支气管肺发育不良。我们报告一例早产女婴,出生时胎龄为25 + 6周,在胎龄为30 + 3周时出现全身性高血压。本病例的病因罕见,血清醛固酮水平偏高,可能提示醛固酮增多症和肾素-血管紧张素-醛固酮系统(RAAS)的过度刺激。我们认为血清醛固酮升高是由动脉导管未闭引起的左向右分流引起的。动脉导管未闭引起的高血压听起来像是一个悖论。然而,在我们的病例中,分流血流被证明是全身性高血压的可能原因。手术关闭分流,高血压得到解决。我们评估了缝合前后血清醛固酮水平和血浆肾素活性,以寻找可能的原因。结论对全身性高血压患儿,应综合考虑可能的病因进行治疗,以预防高血压危象的发生。我们的病例表明,在大量左向右分流流的早产儿中,应考虑高醛固酮增多症和(RAAS)过度刺激的可能性作为严重全体性高血压的原因。
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引用次数: 0
Recurrent neonatal group B streptococcus cellulitis and adenitis syndrome with late-onset sepsis 复发性新生儿B组链球菌蜂窝织炎和腺炎综合征伴迟发性败血症
IF 0.1 Pub Date : 2020-01-01 DOI: 10.1515/crpm-2020-0019
A. Guri, E. Scheier, U. Balla, Mikhael Chigrinsky, Eli Shapiro
Abstract Objectives Group-B streptococcus (GBS) continues to be a significant cause of late-onset neonatal illness. Rarely does it present as cellulitis-adenitis syndrome, and rarely does the infection recur in the same infant after complete recovery. Case presentation Here we report a case of recurrent late-onset cellulitis-adenitis GBS syndrome in a term 12-day-old neonate. The infant presented with fever and cellulitis of the right neck. Full sepsis workup was normal and the infant recovered completely with antibiotics. Three days after the completion of antibiotics the patient returned to the emergency department due to fever, toxic appearance and rapidly spreading cellulitis, and adenitis on the left side of the neck. Blood culture revealed GBS. The patient was re-admitted to the hospital and successfully treated with a prolonged course of antibiotics. Conclusions This case highlights the importance of treating neonatal cellulitis with fever as bacteremia, and reminds us of the rare possibility of recurrent invasive GBS disease. Moreover, this case illustrates that GBS cellulitis-adenitis syndrome is possibly underdiagnosed in mild cases. Physicians should be aware that neonatal cellulitis can precede the appearance of severe sepsis. Neonates with fever and cellulitis without a clear external port of entry should undergo a complete sepsis workup and receive antibiotic treatment appropriate for bacteremia, even if the blood cultures are negative. Although the recurrence of GBS sepsis is rare, physicians should be aware of this possibility in order to treat the infection early.
b群链球菌(GBS)仍然是迟发性新生儿疾病的重要原因。很少表现为蜂窝组织炎-腺炎综合征,并且很少在完全康复后感染在同一婴儿中复发。这里我们报告一例复发迟发蜂窝组织炎-腺炎GBS综合征在足月12天的新生儿。婴儿表现为发烧和右颈部蜂窝织炎。全脓毒症检查正常,婴儿在抗生素治疗下完全康复。抗生素治疗结束3天后,患者因发热、毒性外观及快速扩散的蜂窝织炎和左侧颈部腺炎返回急诊科。血培养显示为GBS。病人再次入院,并成功地接受了延长疗程的抗生素治疗。结论本病例强调了将新生儿蜂窝织炎发热作为菌血症治疗的重要性,并提醒我们注意复发侵袭性GBS疾病的罕见可能性。此外,本病例说明GBS蜂窝组织炎-腺炎综合征在轻度病例中可能被误诊。医生应该意识到新生儿蜂窝织炎可以先于严重败血症的出现。发热和蜂窝织炎的新生儿没有明确的外部入境口,应进行完整的败血症检查,并接受适合菌血症的抗生素治疗,即使血培养为阴性。虽然GBS败血症的复发是罕见的,医生应该意识到这种可能性,以便及早治疗感染。
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引用次数: 0
Septated fetal bladder in a case of 2q13 deletion 2q13缺失1例胎儿膀胱分离
IF 0.1 Pub Date : 2020-01-01 DOI: 10.1515/crpm-2020-0026
María Montenegro del Moral, Gonzalez Isabel, A. I. Padilla Pérez, Margarita Álvarez-de-la-Rosa Rodríguez
Abstract Objectives We aim to report a case of a septated urinary bladder with kidney dysplasia in a fetus presenting with 2q13 microdeletion. Several genes have been related to urogenital malformations. Reports of fetal multi-septated urinary bladder are extremely rare. Deletion 2q13 is responsible for a wide range of phenotypic manifestations but not commonly urogenital diseases. Case presentation We present a case of a primigravida with no contributing history referred to our center for suspected fetal kidney dysplasia. Ultrasound scan at 25 weeks gestation revealed septated urinary bladder and severe pelvic renal dilatation. CGH array showed de novo deletion 2q13. Upon counseling the parents opted for termination. Autopsy confirmed the urinary tract findings and normal external female genitalia. Conclusions To the best of our knowledge this is the first report of a 2q13 microdeletion and septated bladder. We suggest offering genetic counseling at the finding of a septated bladder and determine prognosis upon renal parenchymal destruction.
摘要目的我们报告一例胎儿膀胱分离伴肾发育不良,表现为2q13微缺失。一些基因与泌尿生殖畸形有关。胎儿多裂膀胱的报道是非常罕见的。缺失2q13导致了广泛的表型表现,但不常见的泌尿生殖系统疾病。病例介绍:我们报告一例无病史的初产妇因疑似胎儿肾发育不良而来本中心就诊。妊娠25周超声扫描显示膀胱分离和严重的盆腔肾扩张。CGH阵列显示2q13从头缺失。经咨询,父母选择了终止妊娠。尸检证实了泌尿道检查结果和正常的女性外生殖器。结论:据我们所知,这是第一例关于2q13微缺失和膀胱分离的报道。我们建议在发现膀胱分离时提供遗传咨询,并在肾实质破坏时确定预后。
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引用次数: 0
Management in cases of large uterine myomas in pregnancy 妊娠期大子宫肌瘤的处理
IF 0.1 Pub Date : 2020-01-01 DOI: 10.1515/crpm-2019-0059
A. Stupak, M. Bobiński, Andrzej Miturski, Barbara Kalbarczyk, A. Kwaśniewska, J. Kotarski
Abstract Objectives Uterine fibroids are the most common benign tumors in women of procreative age. The effects of their occurrence affect the course of pregnancy by increasing the frequency of abortions, premature delivery or premature abruption of the placenta. Medical treatment includes clinical observation, pharmacological pain control, myomectomy during pregnancy or perinatal hysterectomy. Case presentation We present a survey of literature and the case of a pregnant woman with an enormous uterine fibroid 23×13×16 cm on the basis of which a diagnostic-therapeutic scheme for tumors of the reproductive organs during pregnancy has been developed. Conclusions The study presents improved recommendations for management the pregnancies in presence of the uterine myomas based on clinical practice.
摘要目的子宫肌瘤是育龄妇女最常见的良性肿瘤。其发生的影响通过增加流产、早产或胎盘早剥的频率来影响妊娠过程。医学治疗包括临床观察、药物止痛、妊娠期子宫肌瘤切除或围产期子宫切除术。病例介绍我们提出了一项文献调查和一个巨大的子宫肌瘤23×13×16厘米孕妇的情况下,在此基础上诊断治疗方案的生殖器官肿瘤在怀孕期间已经发展。结论基于临床实践,本研究提出了子宫肌瘤妊娠处理的改进建议。
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引用次数: 1
Giant congenital vascular malformation: diagnostic approach and clinical course 巨大的先天性血管畸形:诊断方法和临床过程
IF 0.1 Pub Date : 2020-01-01 DOI: 10.1515/crpm-2020-0014
Natasha Mense-Dietrich, V. Mugarab-Samedi, K. Kalaniti
Abstract Objectives Congenital hemangiomas have been well documented, but there remains relatively little information regarding the workup of large or atypical vascular lesions in neonates beyond history and physical exam. Case presentation We report a case of a large congenital hemangioma overlying the anterior chest wall of a term male infant. Imaging by ultrasound and computed tomography (CT) scan confirmed the diagnosis of congenital hemangioma, either non-involuting or rapidly-involuting type. Further imaging supported a plan to manage this case conservatively. Conclusions We present a case of a giant congenital hemangioma overlying most of the chest wall of a term infant and describe the findings on physical exam and imaging, as well as a work-up of similar lesions.
【摘要】目的先天性血管瘤已经有了很好的文献记载,但除了病史和体格检查外,关于新生儿大或非典型血管病变的检查仍然相对较少。我们报告一例巨大的先天性血管瘤覆盖前胸壁的足月男婴。超声和计算机断层扫描证实了先天性血管瘤的诊断,无论是非渐开式还是快速渐开式。进一步的影像学检查支持了保守治疗的计划。结论:我们报告了一例巨大的先天性血管瘤,覆盖了足月婴儿的大部分胸壁,并描述了体格检查和影像学的发现,以及对类似病变的检查。
{"title":"Giant congenital vascular malformation: diagnostic approach and clinical course","authors":"Natasha Mense-Dietrich, V. Mugarab-Samedi, K. Kalaniti","doi":"10.1515/crpm-2020-0014","DOIUrl":"https://doi.org/10.1515/crpm-2020-0014","url":null,"abstract":"Abstract Objectives Congenital hemangiomas have been well documented, but there remains relatively little information regarding the workup of large or atypical vascular lesions in neonates beyond history and physical exam. Case presentation We report a case of a large congenital hemangioma overlying the anterior chest wall of a term male infant. Imaging by ultrasound and computed tomography (CT) scan confirmed the diagnosis of congenital hemangioma, either non-involuting or rapidly-involuting type. Further imaging supported a plan to manage this case conservatively. Conclusions We present a case of a giant congenital hemangioma overlying most of the chest wall of a term infant and describe the findings on physical exam and imaging, as well as a work-up of similar lesions.","PeriodicalId":9617,"journal":{"name":"Case Reports in Perinatal Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75489359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Case Reports in Perinatal Medicine
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