Catheterization and Cardiovascular Interventions最新文献

英文中文

Letter to Editor: Interventional Cardiovascular Magnetic Resonance in Children Undergoing Pre-Operative Fontan Evaluation: One Stop Shop 致编辑的信：介入心血管磁共振在儿童术前Fontan评估：一站式服务。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-04 DOI: 10.1002/ccd.70323

Sundas Adnan Butt

引用次数: 0

Letter to the Editor: Clinical Impact of Concordant and Discordant Physiology Parameters Post-Percutaneous Coronary Intervention in the Easy-Predict Study 致编辑的信：在易预测研究中经皮冠状动脉介入术后生理参数一致和不一致的临床影响。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-04 DOI: 10.1002/ccd.70305

Moeeza Fatima, Husnain Ahmad, Isha Munir, Fatima Qasim

引用次数: 0

Management of Ostial Left Circumflex Artery Lesions With Intravascular Imaging 血管内显像治疗左旋口动脉病变。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-04 DOI: 10.1002/ccd.70324

Ezgi Gültekin Güner, Ahmet Güner, Cemalettin Akman, Kaan Gökçe, Koray Çiloğlu, Fatih Uzun

引用次数: 0

Development and Internal Validation of a Four-Predictor Nomogram for In-Stent Restenosis After Drug-Eluting Stent Implantation in Patients With Overweight/Obesity 超重/肥胖患者药物洗脱支架植入术后支架内再狭窄的四预测因子Nomogram发展与内部验证

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-04 DOI: 10.1002/ccd.70300

Guo-Biao Li, Da-Qing Zhu, Song-Mao Ouyang

Background

In-stent restenosis (ISR) after drug-eluting stent (DES) implantation remains clinically relevant in patients with elevated body mass index (BMI). This study aimed to develop and internally validate a simple nomogram for ISR risk after DES in patients with overweight/obesity.

Aims

To develop and internally validate a simple nomogram for predicting in-stent restenosis (ISR) after drug-eluting stent (DES) implantation in patients with overweight or obesity.

Methods

A single-center retrospective cohort (2018–2023) of adults with BMI ≥ 25 kg/m² receiving first DES was analyzed. ISR was defined as ≥ 50% diameter stenosis within the stent or within 5 mm of its edges on follow-up angiography. Patients were randomly split 70/30 into training and validation cohorts. Four clinically prespecified predictors—smoking, diabetes, total stent length, and stent diameter—were entered into multivariable logistic regression to derive a nomogram. Performance was evaluated by AUC, calibration plots with Hosmer–Lemeshow testing, bootstrapping, and decision curve analysis.

Results

A total of 468 high BMI patients were included, among whom 49 experienced ISR. Multivariate logistic regression analysis revealed smoking, diabetes, stent total length, and stent diameter as factors associated with ISR occurrence. The Nomogram model demonstrated strong predictive performance in both the training and validation sets, with C-index values of 0.753 and 0.729, respectively. Calibration curves and decision curve analysis further confirmed the reliability and clinical utility of the model.

Conclusion

A four-variable nomogram provides pragmatic ISR risk stratification after DES in patients with overweight/obesity, supporting individualized follow-up and secondary prevention. External validation and prospective evaluation are warranted.

背景：药物洗脱支架（DES）植入后支架内再狭窄（ISR）在体重指数（BMI）升高的患者中仍然具有临床意义。本研究旨在开发并内部验证超重/肥胖患者DES后ISR风险的简单nomogram。目的：开发并内部验证一种预测超重或肥胖患者药物洗脱支架（DES）植入后支架内再狭窄（ISR）的简单nomogram。方法：对BMI≥25 kg/m²首次接受DES治疗的成人进行单中心回顾性队列（2018-2023）分析。ISR定义为支架内直径≥50%狭窄或随访血管造影时支架边缘5mm狭窄。患者被随机分成70/30的训练组和验证组。四个临床预先指定的预测因子——吸烟、糖尿病、支架总长度和支架直径——被输入到多变量logistic回归中，得出一个nomogram。通过AUC、Hosmer-Lemeshow测试的校准图、自举和决策曲线分析来评估性能。结果：共纳入468例高BMI患者，其中49例发生ISR。多因素logistic回归分析显示吸烟、糖尿病、支架总长度和支架直径是发生ISR的相关因素。Nomogram模型在训练集和验证集均表现出较强的预测性能，c -指数值分别为0.753和0.729。校正曲线和决策曲线分析进一步证实了模型的可靠性和临床实用性。结论：四变量nomogram为超重/肥胖患者DES后ISR风险分层提供了实用的依据，支持个体化随访和二级预防。外部验证和前瞻性评价是必要的。

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引用次数: 0

“Letter to the Editor: Paclitaxel-Coated Balloons for Femoropopliteal Artery Disease Treatment in French Patients: A Longitudinal Observational Study” “致编辑的信：紫杉醇包覆球囊治疗法国患者股腘动脉疾病：一项纵向观察研究”。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-04 DOI: 10.1002/ccd.70314

Syed Ali Raza Zaidi, Taha Yahya, Suleman Arshad, Meer Hassan Khalid

引用次数: 0

Relationship of Hemodynamic Improvement and Quality of Life Outcomes After Transcatheter Aortic Valve Replacement 经导管主动脉瓣置换术后血流动力学改善与生活质量的关系。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-03 DOI: 10.1002/ccd.70281

Hamza Lodhi, Houman Khalili, Arthur Pavlovsky, Guilherme Attizzani, Sameer Saleem, Sajjad Haider, Mohammad Abdul-Waheed, Muhammad Akbar, Mohammed Kazimuddin, Amr E. Abbas

Background

Transcatheter aortic valve replacement (TAVR) is a rapidly expanding option for patients with severe aortic stenosis. TAVR has been shown to improve both survival and quality of life. However, the relationship between post-TAVR echocardiographic gradient and quality of life has not been well studied or compared in self-expanding (SEVs) and balloon expandable (BEVs) valves.

Aims

To explore correspondence of post-TAVR echocardiographic gradients and quality of life outcomes.

Methods

In a multicenter retrospective registry of patients undergoing TAVR the relationship between discharge mean gradient (MG) on transthoracic echocardiography (TTE) and quality-of-life scores using Kansas City Cardiomyopathy Questionnaire (KCCQ) was examined at 1 month and 1 year.

Results

During the study period, complete data for 1 month KCCQ and discharge MG data was available in 1093 patients from two high volume institutions. These included 410 (37%) SEVs and 683 (63%) BEVs. At discharge, after adjusting for baseline variables, MG was lower with SEV compared to BEV (8.5 ± 4.7 mmHg vs. 10.6 ± 4.9 mmHg, p < 0.001), however change in KCCQ score was similar for both (31.1 ± 21.8 [SEV] vs. 31.7 ± 22.9 [BEVs], p = 0.68). In the combined cohort, discharge MG was not associated with improvement in 1-month or 1-year KCCQ and did not predict change in 1-month or 1-year NYHA class. Patients with higher NYHA classifications exhibited smaller changes in KCCQ scores from baseline at 30 days. (p < 0.001).

Conclusion

In this study of TAVR patients, echocardiogram-derived MG at discharge was not associated with quality-of-life improvement as determined by change in KCCQ or NYHA class at 1 month or 1 year.

背景：经导管主动脉瓣置换术（TAVR）是严重主动脉瓣狭窄患者迅速扩大的选择。TAVR已被证明可以提高生存率和生活质量。然而，tavr后超声心动图梯度与生活质量之间的关系尚未得到很好的研究或比较自扩（sev）和球囊可扩（bev）瓣膜。目的：探讨tavr术后超声心动图梯度与生活质量的对应关系。方法：在TAVR患者的多中心回顾性登记中，使用堪萨斯城心肌病问卷（KCCQ）检查1个月和1年的经胸超声心动图（TTE）出院平均梯度（MG）与生活质量评分之间的关系。结果：在研究期间，来自两家高容量机构的1093例患者获得了1个月的完整KCCQ数据和出院MG数据。其中包括410辆（37%）纯电动汽车和683辆（63%）纯电动汽车。出院时，在调整基线变量后，与BEV相比，SEV的MG较低（8.5±4.7 mmHg vs. 10.6±4.9 mmHg）。结论：在这项TAVR患者的研究中，出院时超声心动图得出的MG与生活质量改善无关，这是通过1个月或1年的KCCQ或NYHA分级的变化来确定的。

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引用次数: 0

Comment on “Impact of Lactate Levels on Admission in STEMI Patients With Cardiogenic Shock Treated With IMPELLA” 对“乳酸水平对STEMI合并IMPELLA治疗心源性休克患者入院的影响”的评论。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-03 DOI: 10.1002/ccd.70295

Mian Zain Hayat, Meer Hassan Khalid, Muhammad Ahmad, Ahmad Furqan Anjum

引用次数: 0

A Novel Propyl Gallate-Based Paclitaxel-Coated Balloon for the Side Branch Treatment in Coronary Bifurcation Lesions 一种新型的以没食子酸丙酯为基础的紫杉醇包被球囊用于冠状动脉分支病变的侧支治疗。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-03 DOI: 10.1002/ccd.70290

Zhifeng Yao, You Zhou, Jiasheng Yin, Yizhe Wu, Li Shen, Hao Lu, Jianying Ma, Juying Qian, Zheyong Huang, Junbo Ge

Background

Drug-coated balloons are emerging as an important approach for the treatment of coronary bifurcation lesions (CBL).

Aims

This study aimed to evaluate the efficacy and safety of a novel paclitaxel-coated balloon (PCB), which used propyl gallate (PG) as the excipient, in treating the side branch of de novo CBL.

Methods

In this multicenter, randomized, non-inferiority trial, 236 patients across 17 centers were 1:1 randomized to the PG-based PCB or iohexol-based PCB groups. After stent deployment in the main vessel, the side branch was dilated with the allocated PCB. Angiographic follow-up was planned at 9 months and clinical follow-up at 12 months. The primary endpoint was diameter stenosis (DS) in the side branch during the angiographic follow-up.

Results

DS in the side branch was 21.3 ± 23.8% in the PG group versus 21.7 ± 24.3% in the control group (p = 0.198). After adjustment for centers, the difference of DS between the PG group and the control group was −0.11% (95% confidence interval, −6.84% to 6.62%), meeting the prespecified non-inferiority margin of 7%. Clinical outcomes at 12 months were comparable between groups.

Conclusions

The PG-based PCB demonstrated non-inferior efficacy and safety in comparison with the iohexol-based PCB for side branch treatment in de novo CBL. The PG-based PCB could be used as a therapeutic alternative in CBL revascularization.

背景：药物包被球囊正在成为治疗冠状动脉分叉病变（CBL）的一种重要方法。目的：评价以没食子酸丙酯（PG）为辅料的新型紫杉醇包被球囊（PCB）治疗新生CBL侧支的疗效和安全性。方法：在这项多中心、随机、非劣效性试验中，来自17个中心的236名患者以1:1的比例随机分为以pg为基础的PCB组或以碘己醇为基础的PCB组。支架置入主血管后，侧支用分配的PCB进行扩张。9个月时进行血管造影随访，12个月时进行临床随访。在血管造影随访期间，主要终点是侧支直径狭窄（DS）。结果：PG组侧支DS为21.3±23.8%，对照组为21.7±24.3% （p = 0.198）。经中心校正后，PG组与对照组的DS差异为-0.11%(95%置信区间，-6.84% ~ 6.62%)，满足预定的7%的非劣效性边际。12个月的临床结果在两组之间具有可比性。结论：与以碘己醇为基础的PCB相比，pg为基础的PCB在治疗新发CBL的侧分支方面具有良好的疗效和安全性。pg基PCB可作为CBL血运重建术的治疗选择。

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引用次数: 0

Are We Missing the Forest for the Trees? How Bayesian Meta-Analysis Could Reshape Evidence in Cardiology 我们是否只见树木不见森林？贝叶斯荟萃分析如何重塑心脏病学证据。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-03 DOI: 10.1002/ccd.70298

Vinícius Martins Rodrigues Oliveira, Lucas M. Barbosa

引用次数: 0

Angioplasty-Assisted, Suture-Mediated Vascular Closure Enabling Percutaneous Transfemoral TAVR in Case of a Diseased Puncture Site. The FEM-PREP Technique 血管成形术辅助，缝合线介导的血管闭合在病变穿刺部位实现经皮经股TAVR。FEM-PREP技术。

IF 1.9 3区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Catheterization and Cardiovascular Interventions

Pub Date : 2025-11-02 DOI: 10.1002/ccd.70285

Agostino Spano', Ole De Backer, Ignacio J. Amat-Santos, Marouane Boukhris, Adrien Jossart, Jacques Auslender, Giuseppe Colletti, Mihai Cocoi, Claudiu Ungureanu

Background

Suture-mediated closure using the ProGlide system can fail during transfemoral transcatheter aortic valve implantation (TAVR) in patients with heavily calcified femoral arteries, complicating vascular access management.

Methods

We describe a case series of three TAVR procedure in which ProGlide pre-closure failed due to calcified plaques impairing footplate apposition, despite accurate ultrasound-guided puncture. Then, a bailout strategy involving femoral angioplasty via a secondary vascular access, the Fem-PREP (Femoral Preparation for Preclosure) technique, was employed to improve vessel compliance and luminal diameter.

Results

The Fem-PREP technique provided minimal space required for adequate ProGlide footplate mobility, reducing plaque interference and enabling successful suture deployment in all cases without vascular complications.

Conclusions

Targeted femoral angioplasty using Fem-PREP may overcome one of the key mechanical limitation associated with pre-closure failure in calcified femoral arteries, offering a simple and effective adjunctive technique in selected TAVR patients.

背景：对于严重钙化的股动脉患者，在经股导管主动脉瓣植入术（TAVR）中，使用ProGlide系统进行缝合关闭可能会失败，使血管通路管理复杂化。方法：我们描述了三例TAVR手术的病例系列，尽管超声引导下准确穿刺，但由于钙化斑块损害了足跖位置，ProGlide预闭合失败。然后，通过次级血管通道进行股骨血管成形术，Fem-PREP（股骨预封闭准备）技术，以改善血管顺应性和管腔直径。结果：Fem-PREP技术提供了足够的ProGlide足板活动所需的最小空间，减少了斑块干扰，并在所有病例中成功展开缝线，无血管并发症。结论：femm - prep靶向股动脉成形术可以克服与钙化股动脉预闭合失败相关的关键力学限制之一，为部分TAVR患者提供了一种简单有效的辅助技术。

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