A total of 332 pregnant women with risk of foetal aneuploidy underwent amniocentesis between January 1991 and August 1992: 247 women (74 per cent) for advanced age over 35 years and 85 younger ones (26 per cent) because of significant risk of Down's syndrome as a result of multimarker screening. Maternal serum alpha-fetoprotein, intact human choriogonadotropin and age were used as variables for combined individual risk evaluation according to Wald et al. The Demo version of ALPHA computer programme was used for risk computations. Two prenatally detected cases of Down's syndrome from a total of 5 were from pregnancies of younger mothers aged 18 and 23 years. Various screening protocols and strategies combining age and biochemical variables are discussed.
{"title":"[Screening for Down's syndrome in the 2d trimester of pregnancy: initial results].","authors":"D Stejskal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A total of 332 pregnant women with risk of foetal aneuploidy underwent amniocentesis between January 1991 and August 1992: 247 women (74 per cent) for advanced age over 35 years and 85 younger ones (26 per cent) because of significant risk of Down's syndrome as a result of multimarker screening. Maternal serum alpha-fetoprotein, intact human choriogonadotropin and age were used as variables for combined individual risk evaluation according to Wald et al. The Demo version of ALPHA computer programme was used for risk computations. Two prenatally detected cases of Down's syndrome from a total of 5 were from pregnancies of younger mothers aged 18 and 23 years. Various screening protocols and strategies combining age and biochemical variables are discussed.</p>","PeriodicalId":9752,"journal":{"name":"Ceskoslovenska gynekologie","volume":"58 1","pages":"5-10"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19306947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The authors evaluate the results of second look operations of ovarian cancer in a group of 34 women. The second look operation was preceded by intraperitoneal and intravenous chemotherapy. This therapeutic protocol contributed to improvement of therapeutic results. In 50% of thus treated women it proved possible to remove the residual tumour and the survival time was prolonged in 75% of women by 1-3 years. The advantages of this therapeutic procedure are according to the authors in particular reduction of the risk of super-radical primary operations and facilitation of the decision whether to terminate treatment or proceed with it.
{"title":"[The role of the second-look operation in modern therapy of ovarian carcinoma].","authors":"A Dörr, L Pilka, J Jelínek, Z Hortíková","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors evaluate the results of second look operations of ovarian cancer in a group of 34 women. The second look operation was preceded by intraperitoneal and intravenous chemotherapy. This therapeutic protocol contributed to improvement of therapeutic results. In 50% of thus treated women it proved possible to remove the residual tumour and the survival time was prolonged in 75% of women by 1-3 years. The advantages of this therapeutic procedure are according to the authors in particular reduction of the risk of super-radical primary operations and facilitation of the decision whether to terminate treatment or proceed with it.</p>","PeriodicalId":9752,"journal":{"name":"Ceskoslovenska gynekologie","volume":"58 1","pages":"11-3"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19305145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Spontaneous rupture of the urinary bladder due to incarceration by the pregnant uterus].","authors":"H Tiser","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9752,"journal":{"name":"Ceskoslovenska gynekologie","volume":"58 1","pages":"20-1"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19306938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Subjective evaluation of urinary incontinence cannot assess the degree of abnormality. Objective assessment of the escape of urine is essential for assessment of the degree of incontinence or for evaluation of the therapeutic results. Therefore a simple standard test was elaborated which can be used for the objective measurement of urinary losses in all patients. The International Continence Society (I.C.S.) recommended in 1983 a one-hour test for objective assessment of escape of urine. The latter assesses the loss of urine by weighing pads or dispers before and after standard activities. The authors tried in their clinical department to assess the significance of a modified 40-minute test in women with urinary incontinence--it was only 44%. They also compared the results of the PWT and Puraclo,max and compared these results with the number of women operated on account of incontinence. In the group of patients with a positive PWT a neg-puraclo,max was recorded in 88.2%. Conversely in patients with a neg-puraclo,max the PWT was positive only in 50%. Surgery was used in neg-puraclo,max in 75% and in positive PWT in 76.6% women. In a negative PWT a neg-puraclo,max was recorded in 65% of the patients of whom 61.5% were operated and two refused operation. In the conclusion the authors emphasize that PWT alone provides only basic objective information on the patient's complaints. The reliability of evaluation of the patient's complaints is increased by complete urodynamic examination.
{"title":"[Personal experience with the modified pad-weight test].","authors":"A Martan, M Halaska, T Koleska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Subjective evaluation of urinary incontinence cannot assess the degree of abnormality. Objective assessment of the escape of urine is essential for assessment of the degree of incontinence or for evaluation of the therapeutic results. Therefore a simple standard test was elaborated which can be used for the objective measurement of urinary losses in all patients. The International Continence Society (I.C.S.) recommended in 1983 a one-hour test for objective assessment of escape of urine. The latter assesses the loss of urine by weighing pads or dispers before and after standard activities. The authors tried in their clinical department to assess the significance of a modified 40-minute test in women with urinary incontinence--it was only 44%. They also compared the results of the PWT and Puraclo,max and compared these results with the number of women operated on account of incontinence. In the group of patients with a positive PWT a neg-puraclo,max was recorded in 88.2%. Conversely in patients with a neg-puraclo,max the PWT was positive only in 50%. Surgery was used in neg-puraclo,max in 75% and in positive PWT in 76.6% women. In a negative PWT a neg-puraclo,max was recorded in 65% of the patients of whom 61.5% were operated and two refused operation. In the conclusion the authors emphasize that PWT alone provides only basic objective information on the patient's complaints. The reliability of evaluation of the patient's complaints is increased by complete urodynamic examination.</p>","PeriodicalId":9752,"journal":{"name":"Ceskoslovenska gynekologie","volume":"58 1","pages":"3-5"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19306942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[150 years since the founding of the Gynecology Clinic in Prague--the first in the world?].","authors":"L Hlavácková","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9752,"journal":{"name":"Ceskoslovenska gynekologie","volume":"58 1","pages":"42-5"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19306945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Evaluation of pelvic floor quality in relation to the method of management of 2d stage labor].","authors":"J Kahánek, V Hrubon","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9752,"journal":{"name":"Ceskoslovenska gynekologie","volume":"58 1","pages":"13-5"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19305146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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