The article notes the latest presented work on the electrochemical detection of insulin and presents a critical view of the research and development of its electrochemical non-enzymatic sensors. It monitors the effect of experimental conditions on the insulin oxidation signal and considers the catalytic effects of nanoparticles or nanocomposites deposited on the surfaces of the electrochemical sensor.
{"title":"Electroanalysis of Insulin on Nanocomposite Electrodes","authors":"Libuše Trnková, Iveta Třísková","doi":"10.54779/chl20230551","DOIUrl":"https://doi.org/10.54779/chl20230551","url":null,"abstract":"The article notes the latest presented work on the electrochemical detection of insulin and presents a critical view of the research and development of its electrochemical non-enzymatic sensors. It monitors the effect of experimental conditions on the insulin oxidation signal and considers the catalytic effects of nanoparticles or nanocomposites deposited on the surfaces of the electrochemical sensor.","PeriodicalId":9766,"journal":{"name":"Chemicke Listy","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The article characterizes existing unused industrial areas, the so-called brownfields, in terms of their usability for hydrogen production, with a focus on electrolytic hydrogen production. The paper also estimates future brownfield areas to ensure hydrogen production.
{"title":"Parameters and Potential of Revitalization of Unused Industrial Areas (Brownfields) for Hydrogen Production","authors":"Petr Polívka, Martin Šilhan","doi":"10.54779/chl20230585","DOIUrl":"https://doi.org/10.54779/chl20230585","url":null,"abstract":"The article characterizes existing unused industrial areas, the so-called brownfields, in terms of their usability for hydrogen production, with a focus on electrolytic hydrogen production. The paper also estimates future brownfield areas to ensure hydrogen production.","PeriodicalId":9766,"journal":{"name":"Chemicke Listy","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luděk Melich, Magdaléna Fořtová, Božena Hosnedlová, Jakub Podhájský, Ondřej Rychlý, Julia Werle, Kristýna Burešová, Kateřina Dunovská, Lenka Vysloužilová, Eva Klapková, Karel Kotaška, Jana Čepová, Blanka Jedličková, Olga Štěpánková, Richard Průša, René Kizek
Metallothionein (MT) is a low molecular weight intracellular protein, the primary function of which is to maintain the homeostasis of heavy metals in living organisms. Only a few research has been carried on the topic molecular mechanism of MT. Recent research points to its significant relationship to carcinogenesis, spontaneous mutagenesis, and the effectiveness of antitumor drugs. Increased level of MT is studied as a potential indicator of increased metabolic activity in cancer. Electrochemical methods are a suitable analytical tool for MT detection. Temperature-denatured blood serum samples of patients diagnosed with cancer were studied using electrochemical analysis (Brdička's reaction). The obtained voltammograms were evaluated as the area under the curve (AUC response). To compare normal and abnormal MT levels, control serum of healthy probands (n = 38) with an average MT amount of 2.2 µg L–1, median 2.1 µg L–1 was used. In all evaluated blood serum samples of cancer patients (n = 228), the average amount of MT was 22.7 µg L–1, and the median was 18.1 µg L–1. The difference (10-fold) between groups was highly statistically significant. The data obtained from the pilot experiment suggest that the levels of thiol compounds such as MT may have clinical potential in cancer patients.
{"title":"Study of Metallothionein Levels in the Serum of Patients with Malignant Tumour","authors":"Luděk Melich, Magdaléna Fořtová, Božena Hosnedlová, Jakub Podhájský, Ondřej Rychlý, Julia Werle, Kristýna Burešová, Kateřina Dunovská, Lenka Vysloužilová, Eva Klapková, Karel Kotaška, Jana Čepová, Blanka Jedličková, Olga Štěpánková, Richard Průša, René Kizek","doi":"10.54779/chl20230573","DOIUrl":"https://doi.org/10.54779/chl20230573","url":null,"abstract":"Metallothionein (MT) is a low molecular weight intracellular protein, the primary function of which is to maintain the homeostasis of heavy metals in living organisms. Only a few research has been carried on the topic molecular mechanism of MT. Recent research points to its significant relationship to carcinogenesis, spontaneous mutagenesis, and the effectiveness of antitumor drugs. Increased level of MT is studied as a potential indicator of increased metabolic activity in cancer. Electrochemical methods are a suitable analytical tool for MT detection. Temperature-denatured blood serum samples of patients diagnosed with cancer were studied using electrochemical analysis (Brdička's reaction). The obtained voltammograms were evaluated as the area under the curve (AUC response). To compare normal and abnormal MT levels, control serum of healthy probands (n = 38) with an average MT amount of 2.2 µg L–1, median 2.1 µg L–1 was used. In all evaluated blood serum samples of cancer patients (n = 228), the average amount of MT was 22.7 µg L–1, and the median was 18.1 µg L–1. The difference (10-fold) between groups was highly statistically significant. The data obtained from the pilot experiment suggest that the levels of thiol compounds such as MT may have clinical potential in cancer patients.","PeriodicalId":9766,"journal":{"name":"Chemicke Listy","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"September, at Last, Chemistry,.... at Long Last!","authors":"Petr Šmejkal","doi":"10.54779/chl20230537","DOIUrl":"https://doi.org/10.54779/chl20230537","url":null,"abstract":"","PeriodicalId":9766,"journal":{"name":"Chemicke Listy","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meniscus-confined electrochemical deposition (MCED) is a promising method for the fabrication of micro- and nanostructures with high precision and resolution. The success of MCED depends on the optimization of several parameters, including duty cycle, voltage, frequency, electrolyte concentration, anode movement speed, anode shape, electrolyte circulation, and additives. Porosity, structure, hardness, yield strength, and composition are the critical factors that determine the quality of deposited structures. This article summarizes the effects of various factors on the outcome of the MCED process, which involves controlled deposition of voxels to create an object. Optimizing these parameters can lead to high-quality structures with good resolution and size. The article points out the relationship between these factors and the resulting properties of the deposited object, which may be useful for future research in this area. It also points to different types of approaches for the preparation of these structures through electrochemical additive manufacturing (ECAM) and its detailed mechanism.
{"title":"Electrochemical Deposition of Micro- and Nanostructures of Any Shape","authors":"Dávid Haluška, Oleksiy Lyutakov, Václav Švorčík","doi":"10.54779/chl20230539","DOIUrl":"https://doi.org/10.54779/chl20230539","url":null,"abstract":"Meniscus-confined electrochemical deposition (MCED) is a promising method for the fabrication of micro- and nanostructures with high precision and resolution. The success of MCED depends on the optimization of several parameters, including duty cycle, voltage, frequency, electrolyte concentration, anode movement speed, anode shape, electrolyte circulation, and additives. Porosity, structure, hardness, yield strength, and composition are the critical factors that determine the quality of deposited structures. This article summarizes the effects of various factors on the outcome of the MCED process, which involves controlled deposition of voxels to create an object. Optimizing these parameters can lead to high-quality structures with good resolution and size. The article points out the relationship between these factors and the resulting properties of the deposited object, which may be useful for future research in this area. It also points to different types of approaches for the preparation of these structures through electrochemical additive manufacturing (ECAM) and its detailed mechanism.","PeriodicalId":9766,"journal":{"name":"Chemicke Listy","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-02-15DOI: 10.1201/9781420007374-37
J. Muselík
Near-infrared (NIR) spectroscopy offers many advantages for a wide range of industrial applications. In combination with multivariate data analysis NIR spectroscopy offers interesting utilization for both qualitative and quantitative analysis. The method is fast and non-destructive and can be implemented in process analysis. The review presents recent pharmaceutical applications of NIR spectroscopy, e.g. in raw materials testing, direct analysis of dosage forms, and process monitoring and process control.
{"title":"Pharmaceutical Applications of Near-Infrared Spectroscopy","authors":"J. Muselík","doi":"10.1201/9781420007374-37","DOIUrl":"https://doi.org/10.1201/9781420007374-37","url":null,"abstract":"Near-infrared (NIR) spectroscopy offers many advantages for a wide range of industrial applications. In combination with multivariate data analysis NIR spectroscopy offers interesting utilization for both qualitative and quantitative analysis. The method is fast and non-destructive and can be implemented in process analysis. The review presents recent pharmaceutical applications of NIR spectroscopy, e.g. in raw materials testing, direct analysis of dosage forms, and process monitoring and process control.","PeriodicalId":9766,"journal":{"name":"Chemicke Listy","volume":"42 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2012-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76242658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The influence of chemical structure on spontaneous polarization, Ps, of a ferroelectric chiral smectic C meso¬phase is discussed. It is shown that the asymmetry, the presence of polar groups in the chiral centre, substitution, the presence of heterocycles in the central skeleton of the molecule and the hindrance of intramolecular rotations are the most important factors for the magnitude of the Ps. A survey of more than 60 compounds is presented including those with spontaneous polarization above 400 nC cm−2.
{"title":"Ferroelectric Liquid Crystals with High Spontaneous Polarization","authors":"S. Pirkl, M. Glogarová","doi":"10.5772/19355","DOIUrl":"https://doi.org/10.5772/19355","url":null,"abstract":"The influence of chemical structure on spontaneous polarization, Ps, of a ferroelectric chiral smectic C meso¬phase is discussed. It is shown that the asymmetry, the presence of polar groups in the chiral centre, substitution, the presence of heterocycles in the central skeleton of the molecule and the hindrance of intramolecular rotations are the most important factors for the magnitude of the Ps. A survey of more than 60 compounds is presented including those with spontaneous polarization above 400 nC cm−2.","PeriodicalId":9766,"journal":{"name":"Chemicke Listy","volume":"32 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2011-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89428472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1999-01-01DOI: 10.1016/s0140-6701(01)80297-6
M. Janik
{"title":"Production of Industrial Carbon Black from Tar Raw Materials in Czechoslovakia.","authors":"M. Janik","doi":"10.1016/s0140-6701(01)80297-6","DOIUrl":"https://doi.org/10.1016/s0140-6701(01)80297-6","url":null,"abstract":"","PeriodicalId":9766,"journal":{"name":"Chemicke Listy","volume":"16 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86926785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：