Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.89
Y. Deng, Junjie Huang, M. Wong
{"title":"IDDF2022-ABS-0023 Associations between six dietary habits and risk of hepatocellular carcinoma: a mendelian randomization study","authors":"Y. Deng, Junjie Huang, M. Wong","doi":"10.1136/gutjnl-2022-iddf.89","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.89","url":null,"abstract":"","PeriodicalId":9921,"journal":{"name":"Chinese Journal of Clinical Hepatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83455191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.110
Engelbert Simon Perillo, Virgilio Lo, Stephen C. Wong
{"title":"IDDF2022-ABS-0171 Frequency and risk factors for complications after ultrasound-guided percutaneous liver radiofrequency ablation in 363 sessions","authors":"Engelbert Simon Perillo, Virgilio Lo, Stephen C. Wong","doi":"10.1136/gutjnl-2022-iddf.110","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.110","url":null,"abstract":"","PeriodicalId":9921,"journal":{"name":"Chinese Journal of Clinical Hepatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90383689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.96
M. Elnagar, M. Saleem, A. Beard, Samantha Whyld, A. Austin
BackgroundNICE recommends offering 6 monthly surveillance with USS for all cirrhotic patients with an exception for patients identified for end-of-life care. But surveillance intervals are often missed when care is delivered through Consultant-led clinics. Having introduced a nurse-led stable cirrhosis clinic in 2016, we assessed whether the recommended interval was being achieved and what impact the ‘aMAP’ score stratifying annual HCC risk as low (<0.2%), medium (1%) and high (4%) might have on service utilisation.MethodsA retrospective review of all patients attending our nurse-led stable cirrhosis clinic. The review included demographic data, aetiology of liver disease, and calculation of aMAP (age, gender, albumin-bilirubin) scores using parameters from initial clinic visits. We assessed adherence to the twice-yearly US scan since our adaptation of NICE guidelines in 2018.ResultsBetween 2016–2018, 117 (49 female) cirrhotic patients were enrolled in the clinic. The majority of the patients had ALD (55) and NASH (24). Other aetiologies: HCV, HFE and PBC. All patients had Child A disease except 7 with Child B7–8. 13/117 patients were excluded from the surveillance because of other co-morbidities and age. Of the remaining, 90(87%) patients had their USS at 6 months interval, 2(2%) missed only one scan (not requested by clinician), 7(7%) failed to attend their appointments, 5(4%) either declined surveillance or were lost to follow up. aMAP score identified 70/104(67%) high risk, 29(28%) medium risk and only 5(5%) low risk for HCC. HCC was diagnosed in 4/104 patients after 3 years of follow-up (2 medium risks;2 high risks). Death was reported in 10 (1HCC;4 liver failure;3 other cancers;1 post-operative complication;1 sepsis). Despite interruptions caused by the COVID-19 pandemic, no HCC was diagnosed in 1st US scan after restarting the services.ConclusionsHCC surveillance organised through a dedicated nurse-led stable cirrhosis clinic can achieve excellent adherence to planned USS intervals. Only a small number were identified as low risk within our cohort using the aMAP score offering limited opportunity to reduce the volume of USS for this indication in Derby.
{"title":"IDDF2022-ABS-0073 HCC surveillance program in a nurse-led clinic: assessing adherence to guidelines and possibility of reducing pressure on services by applying AMAP score","authors":"M. Elnagar, M. Saleem, A. Beard, Samantha Whyld, A. Austin","doi":"10.1136/gutjnl-2022-iddf.96","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.96","url":null,"abstract":"BackgroundNICE recommends offering 6 monthly surveillance with USS for all cirrhotic patients with an exception for patients identified for end-of-life care. But surveillance intervals are often missed when care is delivered through Consultant-led clinics. Having introduced a nurse-led stable cirrhosis clinic in 2016, we assessed whether the recommended interval was being achieved and what impact the ‘aMAP’ score stratifying annual HCC risk as low (<0.2%), medium (1%) and high (4%) might have on service utilisation.MethodsA retrospective review of all patients attending our nurse-led stable cirrhosis clinic. The review included demographic data, aetiology of liver disease, and calculation of aMAP (age, gender, albumin-bilirubin) scores using parameters from initial clinic visits. We assessed adherence to the twice-yearly US scan since our adaptation of NICE guidelines in 2018.ResultsBetween 2016–2018, 117 (49 female) cirrhotic patients were enrolled in the clinic. The majority of the patients had ALD (55) and NASH (24). Other aetiologies: HCV, HFE and PBC. All patients had Child A disease except 7 with Child B7–8. 13/117 patients were excluded from the surveillance because of other co-morbidities and age. Of the remaining, 90(87%) patients had their USS at 6 months interval, 2(2%) missed only one scan (not requested by clinician), 7(7%) failed to attend their appointments, 5(4%) either declined surveillance or were lost to follow up. aMAP score identified 70/104(67%) high risk, 29(28%) medium risk and only 5(5%) low risk for HCC. HCC was diagnosed in 4/104 patients after 3 years of follow-up (2 medium risks;2 high risks). Death was reported in 10 (1HCC;4 liver failure;3 other cancers;1 post-operative complication;1 sepsis). Despite interruptions caused by the COVID-19 pandemic, no HCC was diagnosed in 1st US scan after restarting the services.ConclusionsHCC surveillance organised through a dedicated nurse-led stable cirrhosis clinic can achieve excellent adherence to planned USS intervals. Only a small number were identified as low risk within our cohort using the aMAP score offering limited opportunity to reduce the volume of USS for this indication in Derby.","PeriodicalId":9921,"journal":{"name":"Chinese Journal of Clinical Hepatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75152880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.108
Huttakan Navadurong, K. Laohasurayotin, Kan Yorwittaya, Thodsawit Tiyarattanachai, Natthaporn Tanpowpong, N. Pisuchpen, R. Chaiteerakij, S. Treeprasertsuk, R. Rerknimitr
{"title":"IDDF2022-ABS-0167 Performance of abbreviated magnetic resonance imaging versus ultrasonography as an imaging tool for hepatocellular carcinoma surveillance","authors":"Huttakan Navadurong, K. Laohasurayotin, Kan Yorwittaya, Thodsawit Tiyarattanachai, Natthaporn Tanpowpong, N. Pisuchpen, R. Chaiteerakij, S. Treeprasertsuk, R. Rerknimitr","doi":"10.1136/gutjnl-2022-iddf.108","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.108","url":null,"abstract":"","PeriodicalId":9921,"journal":{"name":"Chinese Journal of Clinical Hepatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81868412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.105
I. Savostyanov, A. Korotkevich
{"title":"IDDF2022-ABS-0145 Comparative effectiveness of different techniques of endoscopic hemostasis in active variceal bleeding","authors":"I. Savostyanov, A. Korotkevich","doi":"10.1136/gutjnl-2022-iddf.105","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.105","url":null,"abstract":"","PeriodicalId":9921,"journal":{"name":"Chinese Journal of Clinical Hepatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87886667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.119
Feng-Yi Cheo, K. Chan, W. Tay, V. Shelat
{"title":"IDDF2022-ABS-0193 Outcomes of preoperative transarterial chemoembolization (TACE) compared to upfront liver resection for large (≥5cm) hepatocellular carcinoma (HCC): a systematic review and meta-analysis","authors":"Feng-Yi Cheo, K. Chan, W. Tay, V. Shelat","doi":"10.1136/gutjnl-2022-iddf.119","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.119","url":null,"abstract":"","PeriodicalId":9921,"journal":{"name":"Chinese Journal of Clinical Hepatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75565966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.1136/gutjnl-2022-iddf.111
Jiahui Pang, Shuru Chen, Meng Yu, Heping Wang, Y. Zeng, Y. Chong, Jiao Gong, W. Gan, Xinhua Li
{"title":"IDDF2022-ABS-0174 The optimal cut-off values of serum ceruloplasmin and urinary copper in the diagnosis of wilson disease in CHB patients","authors":"Jiahui Pang, Shuru Chen, Meng Yu, Heping Wang, Y. Zeng, Y. Chong, Jiao Gong, W. Gan, Xinhua Li","doi":"10.1136/gutjnl-2022-iddf.111","DOIUrl":"https://doi.org/10.1136/gutjnl-2022-iddf.111","url":null,"abstract":"","PeriodicalId":9921,"journal":{"name":"Chinese Journal of Clinical Hepatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74900411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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