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Effectiveness and safety of using acupoint Shui Gou (GV 26): A systematic review and meta-analysis of randomized controlled trials 穴位水沟的有效性和安全性:随机对照试验的系统评价和荟萃分析
Pub Date : 2015-02-01 DOI: 10.1016/j.arthe.2014.12.001
Xiao-Yang Hu , Esme Trevelyan , Qian-Yun Chai , Cong-Cong Wang , Yu-Tong Fei , Jian-Ping Liu , Nicola Robinson

Background

GV26 is well known as an emergency and a revival acupoint. It has been most commonly used for acute neurological conditions and acute low back strain (ALBS). This systematic review evaluates the effectiveness and occurrence of adverse effects of using GV26 for a variety conditions; and to determine the appropriate parameters to inform its use in practice.

Methods

Randomized controlled trials evaluating stimulation of GV26 as a sole or as an adjunct to treatment for any condition were included. Quality of reporting and methodology were assessed using STRICTA and the Cochrane risk of bias tool. Meta-analysis was pooled with RevMan 5.2 software (Protocol ID: CRD42013006528).

Results

Fifteen trials investigated conditions which included shock, epilepsy, vascular dementia, febrile seizures in children, post general anesthesia, acute low back strain, functional enuresis, and intractable hiccups. The reporting quality and methodological quality of all included trials was limited. Data from eleven trials were pooled. Significant favorable improvements were shown for GV26 used in addition to other common acupoints as measured by efficacy rate; GV26 in addition to usual care as measured by blood pressure. No study reported any adverse effects.

Conclusions

There appears to be evidence on the use of GV26 for improving efficacy rate in ALBS, functional enuresis and intractable hiccups, and it appears to be effective in increasing blood pressure and reducing heart rate during revival. However, the findings should be interpreted with caution due to the limited methodological quality of included trials.

dgv26是一个众所周知的急救和复苏穴位。它最常用于急性神经系统疾病和急性腰背劳损(ALBS)。本系统综述评估了在多种条件下使用GV26的有效性和不良反应的发生;并确定适当的参数,以指导其在实践中的使用。方法纳入随机对照试验,评估刺激GV26作为单独或辅助治疗任何疾病的效果。使用STRICTA和Cochrane偏倚风险工具评估报告质量和方法学。meta分析采用RevMan 5.2软件(协议ID: CRD42013006528)。结果15项试验包括休克、癫痫、血管性痴呆、儿童热性惊厥、全身麻醉后、急性腰背劳损、功能性遗尿和顽固性呃嗝。所有纳入试验的报告质量和方法学质量都是有限的。汇总了11项试验的数据。通过有效率测量,GV26与其他常见穴位一起使用,显示出显著的有利改善;GV26在常规护理之外通过血压测量。没有研究报告有任何副作用。结论GV26可提高ALBS、功能性遗尿和顽固性呃逆的有效率,并可在苏醒时提高血压和降低心率。然而,由于纳入试验的方法学质量有限,应谨慎解释研究结果。
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引用次数: 2
Acupuncture as a complement to the pharmacological management of pain, nausea and vomiting after cesarean section: A randomized clinical trial 针刺作为对剖宫产术后疼痛、恶心和呕吐药物管理的补充:一项随机临床试验
Pub Date : 2015-02-01 DOI: 10.1016/j.arthe.2014.12.002
Patrícia Wajnberg Gamermann , Ana Lucia Costa Martins , Leticia Rosa , Hugo Daniel Welter Ribeiro , Daniela Leonetti Borba , Vinicius Antoniazzi , Roberta Rigo Dalla-Corte

Objective

To investigate the effectiveness of acupuncture in addition to routine care, compared with routine care alone, in the treatment of patients with pain, nauseas and vomiting due to cesarean section (CS).

Methods

In a randomized controlled trial, 56 patients post CS were randomly allocated to undergo up to 1 session of real acupuncture or to a control group receiving sham acupuncture with no penetrating needling immediately after spinal anesthesia. All patients were allowed to receive usual medical care for pain, nauseas and vomiting. A satisfaction questionnaire was also applied to puerperal mothers in the first 48 h after the procedure.

Results

The patient characteristics were similar in both groups. No significant difference was found in the incidence of nausea and vomiting and the antiemetic use between groups during the first 24 h and 48 h post-CS. The sham group showed better VAS pain scores at rest in the first 24 h. In the assessment of pain in 48 h there was no difference between acupuncture group and sham group.

Conclusion

This clinical trial using a single session of acupuncture showed no effectiveness of acupuncture in the prevention of pain, nauseas and vomiting after CS. More well-designed studies are needed to define the role of acupuncture on post-CS.

目的探讨针刺加常规护理与单纯常规护理对剖宫产术后疼痛、恶心、呕吐的治疗效果。方法在随机对照试验中,56例脊髓阻滞后患者随机分为两组,一组在脊髓麻醉后立即接受1次真针治疗,另一组接受假针治疗,不穿刺。所有患者都被允许接受常规的疼痛、恶心和呕吐治疗。术后48小时内对产妇进行满意度问卷调查。结果两组患者特征相似。术后24 h和48 h组间恶心、呕吐发生率及止吐药使用差异无统计学意义。针刺组和假手术组在静息后24 h的VAS疼痛评分更好。针刺组和假手术组在48 h的疼痛评分上无明显差异。结论本临床试验采用单次针灸治疗,针刺在预防CS术后疼痛、恶心和呕吐方面没有效果。需要更多精心设计的研究来确定针灸对后cs的作用。
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引用次数: 10
A case series: How do patients with an eating disorder, seeking acupuncture treatment present (patterns of disharmony), and how are they treated? 一个案例系列:寻求针灸治疗的饮食失调患者如何表现(不和谐的模式),他们是如何治疗的?
Pub Date : 2014-12-01 DOI: 10.1016/j.arthe.2014.08.002
Sarah Fogarty , Debra Clydesdale Waldron , Norah McIntire

Acupuncture is an emerging therapy being utilised by those with eating disorders. Little is known about acupuncture and eating disorders. The aim of this paper is to present some TCM insight into the eating disordered patient who seeks acupuncture treatment such as how they present according to TCM principles and how acupuncturists are treating these patients. Three experienced acupuncturists contributed 46 cases studies (eighteen outpatients, twenty six inpatients) of patients with eating disorders who sought acupuncture treatment. Help with their eating disorder was not what the majority of patients in this study sought acupuncture for. The majority of in-patients wanted help for digestive and mood concerns. Our collective cases provide an insight into how eating disorders present and how they are treated by TCM acupuncture. How these insights may help clinicians and researchers is discussed.

针灸是一种新兴的治疗方法,被那些饮食失调的人所使用。人们对针灸和饮食失调知之甚少。本文的目的是为寻求针灸治疗的饮食失调患者提供一些中医见解,例如他们如何根据中医原理呈现以及针灸师如何治疗这些患者。三位经验丰富的针灸师贡献了46例(18例门诊患者,26例住院患者)饮食失调患者寻求针灸治疗的案例研究。在这项研究中,大多数患者寻求针灸治疗并不是为了帮助他们解决饮食失调问题。大多数住院病人需要消化和情绪方面的帮助。我们的集体案例提供了一个洞察饮食失调是如何出现的,以及如何用中医针灸治疗。讨论了这些见解如何帮助临床医生和研究人员。
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引用次数: 2
Report on a case series investigating a neurostimulation device for the treatment of pain and improvement of mobility and function following elbow surgery 研究一种神经刺激装置治疗肘部手术后疼痛并改善活动和功能的病例系列报告
Pub Date : 2014-12-01 DOI: 10.1016/j.arthe.2014.10.001
Phyllis Berger, Jaye Jacks

A group of seven patients received neurostimulation (Stimpod) post-tennis or golfer's elbow surgery as their sole treatment to relieve acute post-operative pain, improve mobility and function. Patients undergoing the above-mentioned surgery have had chronic pain with and without neuropathic symptoms for a prolonged period. There is usually severe injury with active inflammatory processes due to the surgery. It was thought that treating these patients aggressively early post-operatively may expedite pain relief and the healing process.

Method

After their surgery, seven patients were given neurostimulation for three treatments of 20 min each on the brachial plexus during the 10 days before the splint was removed. This was followed by 6 treatments, twice weekly of 20 min each after the splint was removed. At each of these treatments 5-min stimulation were administered to four areas: the nerve supply (1) superior and (2) inferior to the elbow and (3 and 4) on either end of the wound. Patients were evaluated for pain with the visual analogue scale, movements of flexion and extension measured with a goniometer, strength and flexibility with a 12-movement activity scale, status of the wound and satisfaction with treatment, mobility and function. These measures were re-evaluated telephonically at one, three and six months after the last treatment.

Results

Significant pain relief was achieved by all of the seven patients before the splint was removed at the 4th treatment. Pain relief, range of movement and function was greatly improved at the final (9th) treatment by six of the seven patients and this was maintained with nearly full improvement of the above parameters for most of the participants at one month after the last treatment. Two patients had to have re-operation due to requiring more extensive surgery in the one patient and falling and injuring the original surgical site in the other patient. At three and six months after the last treatment full improvement in all the parameters above was maintained in the remaining five patients who also had excellent wound healing and satisfaction with their treatment, mobility and function.

Conclusion

It appears that the neurostimulation (Stimpod) has the capacity to improve acute post-surgical pain and reduce pain, improve mobility, function and stimulate wound healing once the splint was removed. This treatment is relatively cost effective, is non-invasive and of short duration. Positive effects were all maintained at 6 months.

一组7名患者在网球或高尔夫球手肘部手术后接受神经刺激(Stimpod)作为唯一的治疗方法,以缓解急性术后疼痛,改善活动能力和功能。接受上述手术的患者有慢性疼痛,有或无神经性症状,持续时间较长。由于手术,通常有严重的损伤和活跃的炎症过程。人们认为,术后早期积极治疗这些患者可能会加快疼痛缓解和愈合过程。方法7例患者术后10天内分别对臂丛神经进行3次神经刺激,每次20 min,然后取出夹板。随后进行6次治疗,每周2次,每次20分钟后取出夹板。在这些治疗中,分别对四个区域进行5分钟的刺激:神经供应(1)肘关节上(2)肘关节下(3)伤口两端(4)。用视觉模拟量表评估患者的疼痛,用测角仪测量屈伸运动,用12运动活动量表评估患者的力量和柔韧性,伤口状况和对治疗的满意度,活动能力和功能。在最后一次治疗后1个月、3个月和6个月,通过电话对这些措施进行重新评估。结果7例患者在第4次拔除夹板前疼痛均有明显缓解。在最后(第9次)治疗时,7名患者中有6名患者的疼痛缓解、活动范围和功能得到了极大的改善,并且在最后一次治疗后一个月,大多数参与者的上述参数几乎完全改善。2例患者因需要更大范围的手术,而另1例患者因跌倒损伤原手术部位,不得不再次手术。在最后一次治疗后的3个月和6个月,其余5例患者的伤口愈合良好,对治疗、活动能力和功能满意,上述所有参数均保持完全改善。结论神经刺激(Stimpod)具有改善术后急性疼痛、减轻疼痛、改善活动能力和功能、促进夹板拆除后创面愈合的作用。这种治疗相对成本有效,无创且持续时间短。6个月后均保持积极效果。
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引用次数: 1
Efficacy of adjunct (laser) therapy to topical agents among Southern Nigerian acne vulgaris patients 尼日利亚南部寻常痤疮患者局部药物辅助(激光)治疗的疗效
Pub Date : 2014-12-01 DOI: 10.1016/j.arthe.2014.08.003
Canice Chukwudi Anyachukwu, Ogochukwu K.K. Onyeso

This study evaluated the efficacy of Adjunct Laser therapy compared to self-management topical agents among acne vulgaris patients. A parallel randomized controlled trial involving 40 volunteer age ranged 17–28 years (22 ± 4). 35 participants who completed the study were sampled from the stratified 6 faculties’ population of the campus who were screened after meeting the selection criteria and giving the sorted individual consents. Both participants and assessors (physician) were parallel, block and blinded randomized. The outcome measures included distribution and severity of facial acne, counts of baseline lesion of comedones, papule, pustule and nodule, Estimate nos. of face acne eruptions; Mean density of acne calculated and recorded at base line prior each 8 RX sessions in 4 weeks [Density = n/25 cm2 (Initial Density  Present Density = Level of Clearance)]. 2 × 4 × weeks Rx (laser group-invisible infrared non-ablative laser therapy supine lying via 905 nm pulsed single probe [Operation frequency: 2000 Hz ± 10%; Pulse Width: 160 ns ± 10%; Dosage = 5 J/cm2 × 12 min duration]. 10 min Post-RX monitor. Results showed significant improvement in clearance rate of acne (post-laser therapy) relative to their counterparts in control group (54.98% vs. 17.97%, t = 9.773, p = <0.0001, CI = 95%). Conclusively, laser was observed significant adjunct therapy in improving acne clearance rate compared to self-administered topical agent approach only.

本研究评估了辅助激光治疗与自我管理外用药物在寻常痤疮患者中的疗效。一项平行随机对照试验,涉及40名年龄在17-28岁(22±4)岁的志愿者。35名完成研究的参与者从该校6个院系的分层人群中抽样,符合选择标准并给予分类后的个人同意。参与者和评估者(医师)均采用平行、分组和盲法随机。结果测量包括面部痤疮的分布和严重程度,痤疮、丘疹、脓疱和结节的基线病变计数,面部痤疮爆发的估计数量;在4周内每8次RX治疗前的基线上计算和记录痤疮的平均密度[密度= n/25 cm2(初始密度-当前密度=清除水平)]。2 × 4 ×周Rx(激光组)不可见红外非烧蚀激光治疗仰卧经905 nm脉冲单探头[操作频率:2000 Hz±10%;脉冲宽度:160 ns±10%;剂量= 5 J/cm2 × 12 min持续时间]。rx后10分钟。结果显示,与对照组相比,激光治疗后痤疮清除率显著提高(54.98% vs. 17.97%, t = 9.773, p = <0.0001, CI = 95%)。结论:激光辅助治疗在提高痤疮清除率方面比单纯使用局部药物治疗效果显著。
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引用次数: 6
Effects of percutaneous acupuncture stimulation on the viscoelastic properties of tendon during isometric contraction 经皮针刺刺激对肌腱等长收缩时粘弹性的影响
Pub Date : 2014-08-01 DOI: 10.1016/j.arthe.2014.03.003
Toshiyuki Fukushima , Shuichirou Kawamura , Hidenori Horiuti , Masanori Nagaoka

This study aimed to investigate the effects of percutaneous acupuncture stimulation on the viscoelasticity of human tendon structures during isometric contraction. Nine healthy men participated. The experimental order was pre-test, acupuncture stimulation, and post-test. Real and sham acupuncture applications were used at the stimulus site of the medial gastrocnemius muscle (MG), and a crossover trial was performed on the same subjects at a later date. Before and after acupuncture stimulation, tendon elongation and MG aponeurosis were directly measured by ultrasonography while the subjects performed isometric plantar flexions up to the maximum voluntary contraction (MVC) followed by relaxation. The relationship between the estimated MG muscle force (Fm) and tendon elongation (L) during the ascending phase was fitted to a linear regression, the slope of which was defined as the stiffness of the tendon structures. Additionally, the ratio (%) of the area within the Fm–L loop to the area under the curve during contraction and relaxation was calculated and defined as hysteresis. Stiffness rate of change (RC) in real and sham acupuncture was 137.5 ± 116.5% and 55.0 ± 10.4%, respectively (p < 0.05). Thus, real acupuncture demonstrated significantly higher values than sham acupuncture. The hysteresis measurement results in real acupuncture indicated a downward tendency (pre-treatment: 25.6 ± 5.1%, post-treatment: 16.1 ± 13.0%), while sham acupuncture indicated an upward tendency (pre-treatment: 26.5 ± 10.9%, post-treatment: 28.4 ± 6.9%). These results indicated that percutaneous acupuncture stimulation reduces hysteresis, enhances stiffness, and improves the viscoelasticity of tendon structures.

本研究旨在探讨经皮针刺刺激对人体肌腱结构在等长收缩时粘弹性的影响。9名健康男性参与了研究。实验顺序为前测、针刺刺激、后测。在腓肠肌内侧(MG)的刺激部位使用真针和假针,并在晚些时候对同一受试者进行交叉试验。针刺刺激前后,在受试者进行等距足底屈曲至最大自主收缩(MVC)后放松时,直接超声测量肌腱伸长和MG腱膜厚度。上升阶段MG肌力(Fm)与肌腱伸长率(L)之间的关系拟合为线性回归,其斜率定义为肌腱结构的刚度。此外,计算收缩和松弛时Fm-L回路内面积与曲线下面积之比(%),并将其定义为迟滞。真针组和假针组的僵硬变化率(RC)分别为137.5±116.5%和55.0±10.4% (p <0.05)。因此,真实针灸的数值明显高于假针灸。实针组迟滞测量结果呈下降趋势(治疗前:25.6±5.1%,治疗后:16.1±13.0%),假针组迟滞测量结果呈上升趋势(治疗前:26.5±10.9%,治疗后:28.4±6.9%)。这些结果表明,经皮针刺刺激减少了迟滞,增强了刚度,改善了肌腱结构的粘弹性。
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引用次数: 2
Acupuncture targeting and regulating multiple signaling pathways related to Zusanli acupoint using iTRAQ-based quantitative proteomic analysis 基于itraq的定量蛋白质组学分析针刺靶向和调控足三里穴相关的多种信号通路
Pub Date : 2014-08-01 DOI: 10.1016/j.arthe.2014.03.002
Hui Sun, Aihua Zhang, Guangli Yan, Ying-zhi Zhang, Xiang-cai Meng, Li Liu, Ning Xie, Wei-ping Cheng, Xi-jun Wang

Acupuncture has recently gained increased attention in the world as an alternative treatment for diseases, but its metabolism pathways remain understood. Here we use proteomic technology to determine subtle protein changes and link proteins to metabolism pathways. iTRAQ-based quantitative proteomics was used to identify key proteins for acupuncture at ‘Zusanli’ acupoint (ST-36) in subjects. A total of seven related proteins were identified, and these candidates may be useful to clarify the biological mechanism of acupuncture at ST-36. Pathway analysis further revealed that most of these proteins were found to play a pivotal role in the regulation of multiple metabolism pathways.

最近,针灸作为一种治疗疾病的替代疗法在世界上得到了越来越多的关注,但其代谢途径仍不清楚。在这里,我们使用蛋白质组学技术来确定细微的蛋白质变化,并将蛋白质与代谢途径联系起来。采用基于itraq的定量蛋白质组学方法鉴定针刺足三里穴(ST-36)的关键蛋白。共鉴定出7个相关蛋白,这些候选蛋白可能有助于阐明针刺在ST-36位点的生物学机制。通路分析进一步发现,这些蛋白大多在多种代谢途径的调控中发挥关键作用。
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引用次数: 3
A 31 years-old woman with reflex sympathetic dystrophy syndrome (CPRS) 31岁女性反射性交感神经营养不良综合征1例
Pub Date : 2014-08-01 DOI: 10.1016/j.arthe.2014.08.001
Dalamagka Maria, Kontovitsis Christos

A case of a 31 years-old woman with complex regional pain syndrome type I (CRPS) of the left arm is described. Brachial plexus block (BPB) has been cited as a treatment modality for CRPS. This report is based on the retrospective observations of the outcome and effects of axillary BPB in a patient with CRPS. 31 Years-old woman suffered from CRPS of the left upper limb after trauma for 5 months. Symptoms over the left upper limb were not alleviated under conventional pharmacological treatment and rehabilitation and severe painful swelling of the left wrist persisted. Axillary BPB with 30 ml Naropaine 0.2% was performed and 12 h later resulted in significant reduction of pain and improvement of function of the left wrist.

一例31岁的妇女与复杂区域疼痛综合征I型(CRPS)的左臂被描述。臂丛阻滞(Brachial plexus block, BPB)被认为是治疗CRPS的一种方法。本报告基于对一例CRPS患者腋窝BPB治疗的结果和效果的回顾性观察。31岁女性,左上肢外伤后出现CRPS 5个月。左上肢的症状在常规药物治疗和康复治疗下没有得到缓解,左手腕持续存在严重的疼痛肿胀。采用0.2%纳洛卡因30 ml腋窝BPB治疗,12 h后左腕疼痛明显减轻,功能明显改善。
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引用次数: 0
Cluster headache in an elderly patient treated with neurofunctional acupuncture a case report 神经功能针刺治疗丛集性头痛1例
Pub Date : 2014-05-01 DOI: 10.1016/j.arthe.2014.02.002
Julio Cesar Rigo , Claudio Couto , Roberta Rigo Dalla-Corte

Cluster headache (CH) is a trigeminal autonomic cephalalgia and the most painful of the primary headaches. The medical therapy of CH includes both acute therapy for individual attacks and prophylactic therapy to prevent recurrent attacks during the cluster period. Although most patients can be treated effectively, some remain poorly responsive to therapy. The objective of this report is to describe a low cost technique that can be applied in office by a doctor trained in neurofunctional acupuncture and can bring good results for patients with this debilitating disease.

丛集性头痛是一种三叉神经自主神经性头痛,是原发性头痛中最痛苦的一种。CH的医学治疗既包括针对个体发作的急性治疗,也包括防止聚集期复发的预防性治疗。虽然大多数患者可以得到有效治疗,但有些患者对治疗的反应仍然很差。本报告的目的是描述一种低成本的技术,可以在办公室应用的医生在神经功能针灸训练,并能带来良好的结果,患者这种衰弱的疾病。
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引用次数: 1
Improvement of radiation-induced xerostomia with acupuncture: A retrospective analysis 针刺改善放射性口干症的回顾性分析
Pub Date : 2014-05-01 DOI: 10.1016/j.arthe.2014.02.001
Kris A. Homb , Hong Wu , Sergey Tarima , Dian Wang

Objective

Our previous case study introduced combination acupuncture (manual, auricular and electro-acupuncture) as a treatment for radiation-induced xerostomia. The present retrospective study evaluates the effect of combination acupuncture on the severity of dry mouth and activities of daily living as related to radiation-induced xerostomia.

Design

Data was retrospectively collected from twenty-two patients with xerostomia related to radiotherapy for head and neck cancer (HNC). Sixteen patients who met the inclusion and exclusion criteria were analyzed for this report. The intervention was weekly 20 min sessions of combination acupuncture. Upon reaching a plateau in symptom improvement the length in time between treatments was increased as tolerated without return of symptoms. Outcome measures included a self-reported quality of life xerostomia questionnaire completed prior to each acupuncture session and quantitative data from documented Modified Schirmer's tests.

Results

Significant improvement in dry mouth and pain occurred during the initial six weeks of treatment (p < 0.05). During this period, the mean severity of dry mouth and pain decreased by 35% and 50%, respectively (p < 0.001). After six weeks, the improvement in dry mouth and pain symptoms plateaued. This effect was maintained with intermittent acupuncture treatments.

Conclusions

Combination acupuncture significantly decreases the severity of dry mouth and pain with long lasting effects, up to six months (at the end of data collection), in patients with radiation-induced xerostomia.

目的我们之前的案例研究介绍了联合针灸(手针、耳针和电针)治疗放射性口干症。本回顾性研究评估联合针灸对辐射性口干的严重程度和日常生活活动的影响。DesignData回顾性收集了22例头颈癌(HNC)放疗相关的口干症患者。本报告分析了符合纳入和排除标准的16例患者。干预是每周20分钟的联合针灸疗程。在症状改善达到平台期后,两次治疗之间的时间长度在耐受范围内增加,无症状复发。结果测量包括在每次针灸治疗前完成一份自我报告的生活质量口干症问卷和记录的修正Schirmer试验的定量数据。结果在治疗的最初6周内,患者的口干和疼痛均有显著改善(p <0.05)。在此期间,口干和疼痛的平均严重程度分别下降了35%和50% (p <0.001)。六周后,口干和疼痛症状的改善趋于稳定。这种效果在间歇性针灸治疗中得以维持。结论联合针灸治疗可显著降低放射性口干症患者的口干和疼痛的严重程度,且效果持久,可达6个月(数据收集结束时)。
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引用次数: 4
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Acupuncture and Related Therapies
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