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Acupuncture in baby colic 针刺治疗婴儿绞痛
Pub Date : 2013-05-01 DOI: 10.1016/j.arthe.2013.05.001
Marianne Reinthal , Iréne Lund , Thomas Lundeberg
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引用次数: 1
Preliminary evidence of the efficacy of the repetitive muscle vibration therapy in chronic foot drop 重复性肌肉振动治疗慢性足下垂疗效的初步证据
Pub Date : 2013-05-01 DOI: 10.1016/j.arthe.2013.04.001
Filippo Camerota , Claudia Celletti , Romildo Don , Franco Nucci

The tibialis anterior, the main dorsiflexor muscle of the foot, is innervated by the peroneal nerve. Common peroneal nerve lesion represent the most common nerve lesions of the lower limb and can be due to several causative mechanisms. Although the most frequent cause is a common peroneal neuropathy at the neck of the fibula, other causes include anterior horn cell disease, lumbar plexopathies, L5 radiculopathy and partial sciatic neuropathy secondary to total hip replacement. People with common peroneal nerve lesion have a foot drop. In this article we studied the temporal, kinetic and kinematic aspect of gait in a group of nine people who had a chronic foot drop (more than 2 years from the acute event), before and after treatment with focal repetitive muscle vibration on tibial anterior.

胫前肌是足部主要的背屈肌,受腓神经支配。腓总神经病变是下肢最常见的神经病变,可由几种病因机制引起。虽然最常见的原因是腓骨颈部常见的腓神经病变,但其他原因包括前角细胞病、腰椎神经丛病、L5神经根病和全髋关节置换术继发的部分坐骨神经病变。腓总神经病变患者有足下垂。在这篇文章中,我们研究了一组9名患有慢性足下垂(距急性事件超过2年)的人,在胫前部局部重复性肌肉振动治疗前后的时间,动力学和运动学方面的步态。
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引用次数: 3
Amitriptyline prolongs the antihyperalgesic effect of 2 Hz electroacupuncture in mononeuropathic rats 阿米替林可延长2 Hz电针对单神经病变大鼠的镇痛作用
Pub Date : 2013-05-01 DOI: 10.1016/j.arthe.2013.03.001
Rafael Sobrano Fais, Glaucia Melo Reis, Quintino Moura Dias, Ana Carolina Rossaneis, João Walter S. Silveira, Wiliam Alves Prado

Amitriptyline and electroacupuncture (EA) have been used in the management of neuropathic pain. This study examines whether the use of an intraperitoneal injection of amitriptyline changes the effectiveness of EA to reduce neuropathic pain in rats. Changes in the nociceptive threshold of intraperitoneal saline (0.8 ml/kg)- or amitriptyline (0.8 mg/kg)-treated rats were evaluated using the tail-flick test and a model of neuropathic pain before, during and after a 20-min period of 2 Hz EA applied to the Zusanli and Sanynjiao acupoints. The experiments were conducted two or seven days after a sham or chronic constriction injury (CCI) of the sciatic nerve. Amitriptyline had no effect against thermal or neuropathic pain in sham EA-stimulated rats. Two Hz EA increased the tail-flick latency and reduced the mechanical hyperalgesia evoked by the CCI and was more effective against mechanical hyperalgesia when used at the earlier phase of the neuropathic pain than at the later phase. These effects of EA were significantly increased in intensity in the tail-flick test and lasted longer in neuropathic rats after intraperitoneal amitriptyline. The duration of the analgesic effect of 2 Hz EA in the operated hind paws of saline- or amitriptyline-treated rats was longer at two than at seven days after nerve injury. The analgesic effect of EA and its combination with amitriptyline were detected in both sham and CCI rats. The combined effect of amitriptyline and EA may represent an alternative for prolonging the efficacy of EA in the management of neuropathic pain.

阿米替林和电针(EA)已被用于神经性疼痛的管理。本研究探讨腹腔注射阿米替林是否会改变EA减轻大鼠神经性疼痛的有效性。采用甩尾试验和神经性疼痛模型,对足三里和三阴角穴施加2hz电刺激20分钟前、中、后腹腔注射生理盐水(0.8 ml/kg)或阿米替林(0.8 mg/kg)处理大鼠的伤害性阈值变化进行评价。实验是在假性或慢性坐骨神经收缩损伤(CCI)后2天或7天进行的。阿米替林对假性ea刺激大鼠的热痛和神经性疼痛无影响。2hz EA增加了甩尾潜伏期,减少了CCI引起的机械性痛觉过敏,并且在神经性疼痛的早期使用比在后期使用更有效。神经病变大鼠腹腔注射阿米替林后,EA的这些作用在甩尾试验中显著增强,持续时间更长。2 Hz EA对生理盐水或阿米替林治疗大鼠术后后爪的镇痛作用持续时间2天长于神经损伤后7天。观察EA及与阿米替林联用对假手术大鼠和CCI大鼠的镇痛作用。阿米替林和EA的联合作用可能是延长EA治疗神经性疼痛疗效的一种选择。
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引用次数: 0
The needling sensation: A factor contributing to the specific effects of acupuncture? 针刺的感觉:对针灸的特殊效果起作用的一个因素?
Pub Date : 2012-01-01 DOI: 10.1016/j.arthe.2012.12.001
Thomas Lundeberg , Iréne Lund , Jan Näslund

Acupuncture is a complex intervention, and there are both specific and non-specific influences associated with its therapeutic benefit. Although large randomized controlled trials (RCT) and systematic reviews have demonstrated the efficacy of acupuncture, the conclusions are controversial due to the lack of a significant difference in the results between real and sham acupuncture. This similarity may be due to the omission of important components of the acupuncture treatment itself, such as the needling sensation. The needling sensation is considered to represent an important component of acupuncture. Despite this importance, several RCTs have lacked data on whether the needling sensation has been achieved. From a Traditional Chinese Medicine (TCM) perspective, the needling sensation, deQi, is a combination of unique sensations that are interpreted as the flow of Qi, or “vital energy.” Furthermore, acupuncture is believed to be successful only upon the arrival of “vital energy,” Qi. This state is suggested to be essential to the specific therapeutic effect of acupuncture. From a biomedical perspective, acupuncture excites sensory receptors and nerve fibers in the stimulated tissue, resulting in a needling sensation. Moreover, acupuncture induces both the deactivation of a limbic–paralimbic–neocortical network in the brain (the default mode network and the anti-correlated task-positive network) and the activation of somatosensory regions. A distinct needling sensation is associated with a marked deactivation of these brain networks, whereas the lack of a needling sensation (as during sham needling) is associated with significantly less deactivation. Conversely, when acupuncture induces sharp pain sensations, there is an activation of these networks instead. In a clinical context, this difference means that the therapist needs to identify a stimulation intensity that is scaled to the needling response of each patient, i.e., a sharp uncomfortable pain sensation during the needle stimulation should be avoided.

Both the empirical bases of TCM and biomedical acupuncture research suggest that the therapist should strive for a needling sensation during an acupuncture treatment. If such a sensation is not achieved, are the specific effects of acupuncture likely smaller? This conclusion suggests that deQi is part of a proper acupuncture treatment and that the experience of a needling sensation should universally be assessed and reported in all types of clinical and experimental trials.

针灸是一种复杂的干预措施,其治疗效果既有特异性影响,也有非特异性影响。虽然大型随机对照试验(RCT)和系统评价已经证明了针灸的疗效,但由于在真针灸和假针灸之间的结果缺乏显着差异,因此结论存在争议。这种相似性可能是由于针灸治疗本身的重要组成部分的遗漏,如针刺的感觉。针刺的感觉被认为是针灸的一个重要组成部分。尽管这一点很重要,但一些随机对照试验缺乏关于针刺感觉是否已经实现的数据。从中医的角度来看,针刺的感觉,德气,是一种独特的感觉组合,被解释为气的流动,或“生命能量”。此外,针灸被认为只有在“生命能量”气到来时才会成功。这种状态被认为对针灸的特殊治疗效果至关重要。从生物医学的角度来看,针灸刺激了受刺激组织中的感觉受体和神经纤维,从而产生针刺感。此外,针刺诱导大脑边缘-旁边缘-新皮层网络(默认模式网络和反相关任务-正网络)的失活和体感觉区域的激活。明显的针刺感与这些大脑网络的明显失活有关,而缺乏针刺感(如在假针刺期间)与明显较少的失活有关。相反,当针灸引起剧烈的痛觉时,这些神经网络反而被激活了。在临床环境中,这种差异意味着治疗师需要确定一个刺激强度,该强度与每个患者的针刺反应相匹配,即,在针刺刺激期间应避免剧烈的不舒服的疼痛感。中医和生物医学针灸研究的经验基础都表明,在针灸治疗过程中,治疗师应该努力获得针刺的感觉。如果没有达到这种感觉,针灸的具体效果是否可能更小?这一结论表明,德气是正确针灸治疗的一部分,针刺感觉的体验应该在所有类型的临床和实验试验中普遍评估和报告。
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引用次数: 13
Is compassion a part of the non-specific effects of acupuncture? 同情是针灸非特异性效果的一部分吗?
Pub Date : 2012-01-01 DOI: 10.1016/j.arthe.2012.12.003
Thomas Lundeberg , Iréne Lund , Jan Näslund

Acupuncture is widely used for the treatment of chronic (long-term) pain. In a recent study, Vickers et al. characterized the analgesic effect of acupuncture in four different chronic pain conditions, back and neck pain, osteoarthritis, headache, and shoulder pain, and concluded that acupuncture is an effective type of treatment for these chronic pain states.

Significant differences between true and sham acupuncture indicate that acupuncture induces superior effects. However, these differences were reported to be relatively modest, suggesting that non-specific effects, in addition to the specific effects of the needle stimulation, are important contributors to the therapeutic effects of acupuncture. It has been demonstrated that two factors that are seen as non-specific are related to individual therapists’ interaction with the patient and the patients’ positive expectation of the treatment effect.

The therapist–patient interaction has been shown to be unrelated to empathy but may be attributable to the ability to express compassion. Compassion implies being attuned to undeserved suffering, but it is also a signaling behavior related to care giving that has physiological responses that orient the individual to social interaction. It is possible that therapists that report good treatment outcomes are more compassionate in their interaction with their patient compared to the therapist reporting poor outcomes.

针灸被广泛用于治疗慢性(长期)疼痛。在最近的一项研究中,Vickers等人描述了针灸在四种不同的慢性疼痛状态下的镇痛作用,即背部和颈部疼痛、骨关节炎、头痛和肩部疼痛,并得出结论,针灸是治疗这些慢性疼痛状态的有效方法。真针与假针的显著性差异表明,针刺具有更好的疗效。然而,据报道,这些差异相对较小,这表明除了针刺刺激的特异性效果外,非特异性效果也是针灸治疗效果的重要贡献者。研究表明,有两个被视为非特异性的因素与个体治疗师与患者的互动和患者对治疗效果的积极期望有关。医患互动已被证明与共情无关,但可能归因于表达同情的能力。同情意味着对不应该遭受的痛苦有所适应,但它也是一种与关怀有关的信号行为,它具有使个体适应社会互动的生理反应。与报告不良结果的治疗师相比,报告良好治疗结果的治疗师在与患者的互动中可能更富有同情心。
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引用次数: 0
Neural therapy—A review of the therapeutic use of local anesthetics 神经治疗-局部麻醉剂治疗应用的综述
Pub Date : 2012-01-01 DOI: 10.1016/j.arthe.2012.12.004
Stefan Weinschenk

Neural therapy, or therapeutic local anesthesia (TLA), is the diagnostic and therapeutic use of local anesthetics. This review summarizes the scientific and clinical evidence, indications, methods of application, and possible future research.

In the literature, there is a gap between the multitude of data supporting a number of different molecular effects and the few clinical trials that are available. The available clinical studies and case reports, however, show effectiveness in acute and chronic pain, functional disorders, vegetative diseases such as the complex regional pain syndrome (CRPS), and chronic inflammation.

Five administration methods are described: local, segmental, regional, and systemic application, as well as injections into the so called “stoerfeld” (disturbance field, interference field).

Local anesthetics have been used for therapy for over 120 years, which suggests that this therapy may be an important, effective, and efficient therapy that has few side-effects. Possible clinical studies to reveal the potential effectiveness and benefit-risk ratio of this holistic approach are described.

神经治疗,或治疗性局部麻醉(TLA),是局部麻醉剂的诊断和治疗用途。本文综述了科学和临床证据、适应症、应用方法以及未来可能的研究。在文献中,支持许多不同分子效应的大量数据与可用的少数临床试验之间存在差距。然而,现有的临床研究和病例报告显示,在急性和慢性疼痛,功能障碍,植物性疾病,如复杂区域疼痛综合征(CRPS),慢性炎症有效。描述了五种给药方法:局部、局部、局部和全身应用,以及注射到所谓的“斯托菲尔德”(干扰场,干扰场)。局部麻醉剂用于治疗已有120多年的历史,这表明这种治疗可能是一种重要、有效、高效的治疗方法,而且副作用很少。可能的临床研究,以揭示潜在的有效性和利益-风险比,这种整体方法描述。
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引用次数: 43
Time for a modern view of acupuncture and related therapies 是时候对针灸和相关疗法进行现代观察了
Pub Date : 2012-01-01 DOI: 10.1016/j.arthe.2012.12.002
Thomas Lundeberg
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引用次数: 0
期刊
Acupuncture and Related Therapies
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