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The clinical implications of referred muscle pain sensation 牵涉肌痛觉的临床意义
Pub Date : 1994-03-01 DOI: 10.1016/S1058-9139(05)80228-1
Paolo Marchettini , José Ochoa
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引用次数: 4
APS board briefs APS董事会简报
Pub Date : 1994-03-01 DOI: 10.1016/S1058-9139(05)80242-6
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引用次数: 0
Rebuttal to the comments of Dr. Bullitt and professor Basbaum 反驳布利特博士和巴斯鲍姆教授的评论
Pub Date : 1994-03-01 DOI: 10.1016/S1058-9139(05)80238-4
Manfred Zimmermann, Thomas Herdegen
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引用次数: 1
Highlights of the APS 12th Annual Scientific Meeting 美国科学学会第12届年度科学会议亮点
Pub Date : 1994-03-01 DOI: 10.1016/S1058-9139(05)80240-2
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引用次数: 0
Mediators of spinal hyperexcitability and hyperalgesia 脊髓高兴奋性和痛觉过敏的介质
Pub Date : 1993-12-01 DOI: 10.1016/S1058-9139(05)80260-8
Donald A. Simone
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引用次数: 1
Rebuttal of commentaries concerning the focus article 对焦点文章评论的反驳
Pub Date : 1993-12-01 DOI: 10.1016/S1058-9139(05)80250-5
Peter J. Jannetta
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引用次数: 1
In what language do nerve cells communicate? 神经细胞用什么语言交流?
Pub Date : 1993-12-01 DOI: 10.1016/S1058-9139(05)80255-4
Patrick D. Wall
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引用次数: 0
Spinal mediators of nociceptive neurotransmission and hyperalgesia 痛觉神经传递和痛觉过敏的脊髓介质
Pub Date : 1993-12-01 DOI: 10.1016/S1058-9139(05)80257-8
George L. Wilcox

The synaptic mechanisms of nociception, hyperalgesia, allodynia, opioid tolerance, and neuropathic pain in the spinal cord dorsal horn are explored. The characteristics of the transmitters conveying excitation and the mechanisms that can enhance synaptic efficacy in the spinal nociceptive system after prolonged stimulation are examined, and a possible sequence of events that could contribute to progressive development, after intense or pathologic stimulation, of enhanced neuronal responsiveness from initial synaptic plasticity and hyperalgesia to subsequent neurotoxicity and neuropathic pain is described. The progression includes neurokinins and excitatory amino acids as neurotransmitters acting at neurokinins and excitatory amino acids receptors and evoking the production of nitric oxide by spinal interneurons. Finally, the importance of spinal blood flow as an affected function and an effective participant is discussed.

突触机制的痛觉,痛觉过敏,异常性疼痛,阿片耐受性和神经性疼痛在脊髓背角的探讨。我们研究了在长时间刺激后,传递兴奋的递质的特性和增强脊髓痛觉系统突触效能的机制,并描述了在强烈或病理性刺激后,从最初的突触可塑性和痛觉过敏到随后的神经毒性和神经性疼痛,促进神经元反应性增强的可能事件序列。这一过程包括神经激肽和兴奋性氨基酸作为神经递质作用于神经激肽和兴奋性氨基酸受体,并引起脊髓中间神经元产生一氧化氮。最后,讨论了脊髓血流作为受影响功能和有效参与者的重要性。
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引用次数: 29
1993 APS award winners 1993年APS奖得主
Pub Date : 1993-12-01 DOI: 10.1016/S1058-9139(05)80261-X
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引用次数: 0
Vascular compression is the cause of trigeminal neuralgia 血管受压是三叉神经痛的病因
Pub Date : 1993-12-01 DOI: 10.1016/S1058-9139(05)80247-5
Sean Mullan
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引用次数: 0
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