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Risk Factors and Predictive Scoring System Development for COVID-19 Death COVID-19死亡的危险因素和预测评分系统开发
Q3 Medicine Pub Date : 2020-12-15 DOI: 10.12114/J.ISSN.1007-9572.2020.00.555
Ling Chen, J. Chen, Yuwei Liu, Xuebei Du, Li Peng, Ya-lei Jin, Haoxiang Wang, Yan Zhao
Background: The COVID-19 has become a global epidemic How to effectively treat it and reduce the fatality rate is still at exploratory stage Identification of risk factors for death is critical to optimize treatment strategies for COVID-19 Objective: To investigate risk factors for COVID-19 death, and based on this, to develop a COVID-19 death predictive scoring system Methods: Two hundred and seventy patients, who discharged or deceased with confirmed COVID-19 in Zhongnan Hospital of Wuhan University during January 1 to February 29, 2020, were reviewed Baseline data were obtained, including demographics, admission symptoms and vital signs, complications and laboratory test results According to the clinical outcome, i e discharged and deceased, the patients were divided into recovery group and death group Risk factors of death were explored by using multivariate logistic regression analysis, and used for the development of a predictive scoring system for death Results Two hundred and forty-five cases were finally included, including 212 discharged and 33 deceased during hospitalization Factors independently associated with death were age ≥ 65 years〔OR=7 177, 95%CI(1 715, 30 038), P<0 05〕, SpO2≤93%〔OR=15 456, 95%CI(3 343, 71 450), P<0 05〕, BUN≥7 mmol/L〔OR=7 115, 95%CI(1 550, 32 652), P<0 05〕, PCT≥0 1 μg/L〔OR=23 895, 95%CI(4 209, 135 639), P<0 05〕 In predicting death due to COVID-19, the AUC of ASBP(A: age, S: SpO2, B: BUN, P: PCT) scoring system was 0 967〔95%CI(0 931, 0 987)〕, and that of CURB-65 scoring system was 0 885〔95%CI(0 831, 0 926)〕, showing a significant difference(Z=2 816, P<0 01) 5 was the maximal Youden Index for ASBP scoring system and was chosen as the cut-off value, with 0 871 sensitivity and 0 957 specificity And 2 was the maximal Youden Index for CURB-65 scoring system and was chosen as the cut-off value, with 0 903 sensitivity and 0 735 specificity Conclusion: Older age, lower SpO2, higher levels of BUN and PCT were independent risk factors for COVID-19 death, and the ASBP scoring system developed based these factors might be available for the assessment of death risk of COVID-19 Copyright © 2020 by the Chinese General Practice
背景:新冠肺炎已成为全球流行病如何有效治疗并降低病死率仍处于探索阶段识别死亡风险因素对于优化新冠肺炎治疗策略至关重要目的:调查新冠肺炎死亡的风险因素,并在此基础上,建立新冠肺炎死亡预测评分系统方法:回顾武汉大学中南医院2020年1月1日至2月29日因确诊新冠肺炎出院或死亡的270例患者的基线数据,包括人口统计学、入院症状和生命体征,并发症和实验室检查结果根据临床转归,即出院和死亡,将患者分为康复组和死亡组。采用多元逻辑回归分析探讨死亡的危险因素,并用于开发死亡预测评分系统。结果最终纳入245例,其中出院212例,住院期间死亡33例与死亡独立相关的因素为年龄≥65岁〔OR=7 177,95%CI(1 715,30 038),P<005〕,SpO2≤93%〔OR=15 456,95%CI(3 343,71 450),P>001〕,BUN≥7 mmol/L〔OR=7 115,95%Cl(1 550,32 652,ASBP(A:年龄,S:SpO2,B:BUN,P:PCT)评分系统的AUC为0 967〔95%CI(0 931,0 987)〕,CURB-65评分系统的AUC为0 885〔95%CI(0 831,0 926)〕,以0 871敏感性和0 957特异性,2是CURB-65评分系统的最大尤登指数,并被选为临界值,敏感性为0 903,特异性为0 735。结论:年龄较大、SpO2较低、BUN和PCT水平较高是新冠肺炎死亡的独立危险因素,基于这些因素开发的ASBP评分系统可能可用于评估新冠肺炎的死亡风险版权所有©2020中国全科医学
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引用次数: 0
The Incidence and Epidemic Characteristics of Medical Staff's Skin Injuries Caused by Personal Protective Equipment for Fighting against 2019-nCoV Infection 新型冠状病毒感染防护用品致医务人员皮肤损伤的发生率及流行特征
Q3 Medicine Pub Date : 2020-03-20 DOI: 10.12114/J.ISSN.1007-9572.2020.00.315
Qixia Jiang, Yuxiu Liu, Wei Wei, Aihua Chen, Yuxuan Bai, Yinghua Cai, Liande Tao, Yongli Tang, Zhixia Jiang, Gui-fu Xu, Laijuan Li, Jiayu Xue, Jian Xiao, Xiaokun Li
Background: The medical device-related pressure injury(DRPI), which mainly occurs in critical patients and orthopedic patients, has been a research hotspot for the safety management and specialized care of inpatients worldwide, but there have been few reports on DRPI of medical staff During the prevention and control of COVID-19, a large number of medical staff are fighting at the front However, wearing protective equipment for a long time can easily cause skin injury, which seriously harms the medical staff and increases their risk of infection Therefore, how to protect medical personnel from skin damage is an urgent problem Objective: To investigate the incidence and epidemic characteristics of medical staff's skin injuries caused by personal protective equipment in fighting against the COVID-19 in order to provide a basis for the formulation of effective protection countermeasures Methods: A research questionnaire was developed by our research group, including the basic information of medical staff, the wearing situation of protective equipment, the skin damage situation, preventive measures against skin damage, and the post-injury treatment The questionnaire was released through the Questionnaire Star website to front-line medical staff fighting against the COVID-19 through Wechat app from February 8 to 15 in 2020 The survey was completed by voluntary participation and online filling The survey data were collected in one week and a database was established Statistical analysis was made on the incidence of skin injuries, the types of injuries, and epidemic characteristics Results: A total of 2 901 effective questionnaires were collected from 145 hospitals in 19 provinces, 3 autonomous regions and 4 municipalities in China Among them, there were 214(7 38%) males and 2 687(92 62%) females, and 147(5 07%) doctors and 2 754(94 93%) nurses And 825(28 44 %) cases of the medical staff suffered skin injuries due to wearing protective equipment, and the total number of skin damage sites was 2 794 The main types of skin injuries were pressure injury〔771(26 58%)cases, 2 53 per capita〕, moisture-associated skin damage〔256(8 83%)cases, 2 77 per capita〕, and skin tear〔42(1 45%)cases, 3 12 per capita〕 Of the 825 medical staff who had skin injuries, 221(26 79%) cases had skin injuries≥2 types Univariate analysis showed that the incidence of skin injuries caused by protective equipment was higher in men than in women(P 0 05), in those aged 31-45 than in those ≤30(P 0 016 7), in those who worked 10 years than in those who worked 5 years(P 0 016 7), in doctors than in nurses(P 0 05), in designated epidemic prevention hospitals in Wuhan than in other hospitals(P 0 003 3)and among other hospitals, in Infectious Disease Department than in other departments(P 0 003 3), and in tertiary protection than in secondary protection followed by primary protection(P 0 016 7) However, there was no significant difference in the incidence of skin injuries among medical staff wit
背景:医疗器械相关压力损伤(DRPI)主要发生在危重症患者和骨科患者中,一直是世界范围内住院患者安全管理和专科护理的研究热点,但关于医务人员DRPI的报道很少。在防控新冠肺炎期间,大量医务人员在前线作战,但长时间佩戴防护装备容易造成皮肤损伤。因此,如何保护医务人员免受皮肤损伤是一个迫切需要解决的问题。目的:调查在抗击新冠肺炎疫情中,医务人员因个人防护装备造成的皮肤损伤的发生率和流行特征,为制定有效的防护对策提供依据。课题组制定了一份调查问卷,调查内容包括医务人员基本情况、防护装备佩戴情况、皮肤损伤情况、皮肤损伤预防措施、调查问卷于2020年2月8日至15日通过“问卷之星”网站通过微信app向一线抗疫医务人员发放,采用自愿参与、在线填写的方式完成调查,一周内收集调查数据并建立数据库,对皮肤损伤发生率、损伤类型、流行特征进行统计分析:共有901份有效问卷145医院在19个省份,在中国3个自治区、4个直辖市,有214男性和2(7 38%)687(92 62%)的女性,和147年(5 07%)医生和754(94 93%)护士和医务人员的825例(44%)28日皮肤受伤由于穿防护设备,和皮肤损伤的总数是794皮肤受伤的压力损伤的主要类型(771例(58%)26日病例,2人均53],moisture-associated皮肤损伤[256(8 83%)情况下,2人均77),和皮肤撕裂[42(1 45%)情况下,3人均12)825名医务人员的皮肤受伤,221例(79%)26日有皮肤损伤≥2类型单变量分析表明,防护设备引起的皮肤损伤的发病率男性高于女性(P 0 05),在那些年龄在31 - 45岁比≤30 (P 0 016 7),在那些工作10年比(P 0 016 7)工作了5年,在武汉市定点防疫医院中,医生多于护士(P < 0.05),在武汉市定点防疫医院中,传染病科多于其他医院(P < 0.001),在三级防护中多于二级防护后为一级防护(P < 0.01)。不同连续穿戴防护用品时间的医务人员皮肤损伤发生率差异无统计学意义(P < 0.05)结论医务人员在抗新冠肺炎疫情中因个人防护用品引起的皮肤损伤发生率较高,存在多类型、多部位皮肤损伤并存的情况,建议采取减压、减摩、吸湿、防感染、防感染等综合防护措施。同时,建议关注性别、年龄、工作岗位等人力资源管理因素版权所有©2020由中国全科医生
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引用次数: 5
Guidance on the Control and Prevention of SARS-CoV-2 Infection in Primary Healthcare Settings in Rural China(First Edition) 中国农村基层医疗机构控制和预防严重急性呼吸系统综合征冠状病毒2型感染指南(第一版)
Q3 Medicine Pub Date : 2020-03-05 DOI: 10.12114/J.ISSN.1007-9572.2020.00.246
Dongying Zhang, M. Yao, Jiaji Wang, D. Ye, Qin Chen, F. Guo, Chuan Zou, Kai Lin, hui lu, Xiang Huang, Jinping Zheng, Chunhua Chi, N. Zhong
Since the outbreak of the COVID-19, all regions of China have carried out prompt responsive actions in an active way to control and prevent the disease, among which rural areas face particularly severe challenges, because they are the weak link in the control and prevention of public health emergencies due to shortage of health resources and poor diagnostic and therapeutic level According to characteristics and the actual situation of the current rural primary healthcare settings, this guidedance introduced the requirements of setting environmental space for epidemic prevention and control, the process of referral, home observation, persons with special health care, health education for villagers, personal protection for health staff, and nosocomial infection control It would provide a standardized and safe way for primary healthcare settings in rural areas in the epidemic prevention and control Copyright © 2020 by the Chinese General Practice
新冠肺炎疫情发生以来,中国各地积极开展疫情防控工作,其中农村地区面临特别严峻的挑战,由于卫生资源短缺、诊疗水平差,是突发公共卫生事件防控的薄弱环节。根据当前农村基层卫生机构的特点和实际情况,本指南介绍了设置疫情防控环境空间的要求,转诊过程、居家观察、特殊健康护理人员、村民健康教育、卫生人员个人防护和医院感染控制这将为疫情防控中的农村初级保健提供一种标准化和安全的方式版权所有©2020中国全科医学
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引用次数: 6
The Application Value and Safety Analysis of Capsule Endoscopy in the Diagnosis of Elderly Small Intestine Diseases 胶囊内镜在老年小肠疾病诊断中的应用价值及安全性分析
Q3 Medicine Pub Date : 2018-10-20 DOI: 10.3969/J.ISSN.1007-9572.2018.00.178
Li Xianmin, Zhang Yu, Tian Xiaoxiao, Zhu Jingjing, Jin Jianjun
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引用次数: 0
Effect of Mild Moxibustion on TRPV1 Expression in the Dorsal Root Ganglion in a Mouse Model of Pruritus Ani 微灸对瘙痒症小鼠背根神经节TRPV1表达的影响
Q3 Medicine Pub Date : 2018-10-20 DOI: 10.12114/J.ISSN.1007-9572.2018.00.241
Xu Li, Ge Qiongxiang, L. Guoqiang
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引用次数: 0
Modified Scarf and Akin Osteotomies for the Treatment of Moderate to Severe Hallux Valgus 改良丝巾及Akin截骨术治疗中重度拇外翻
Q3 Medicine Pub Date : 2018-04-15 DOI: 10.3969/j.issn.1007-9572.2017.00.265
Z. Lan, Z. Zhi, Lin Li-gong
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引用次数: 0
Functional Connectivity of Default-Mode Network Related Brain Regions in Female Patients with Depression: a Resting-State Functional Magnetic Resonance Imaging Study 女性抑郁症患者默认模式网络相关脑区功能连接的静息状态功能磁共振成像研究
Q3 Medicine Pub Date : 2018-02-20 DOI: 10.3969/j.issn.1007-9572.2018.00.017
Zhang Han, L. Ying, Jinmin Liao, Xilin Wang, Li Jing, Zhao Bing, Man-man Chen
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引用次数: 25
Interpretation of Exercise Management in Type 1 Diabetes: a Consensus Statement in 2017 解读1型糖尿病的运动管理:2017年的共识声明
Q3 Medicine Pub Date : 2017-12-20 DOI: 10.3969/J.ISSN.1007-9572.2017.00.208
Z. Qiu, D. Wen-li
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引用次数: 0
Status of Pre-hospital Delay and Influencing Factors of Delay Time in Patients with Colorectal Cancer 癌症大肠癌患者术前延迟的现状及影响延迟时间的因素
Q3 Medicine Pub Date : 2017-11-01 DOI: 10.3969/J.ISSN.1007-9572.2017.00.138
Xiao Wu, C. Chen, H. Chao, M. Zheng, P. Ding, Wu Jiang, H. Qin
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引用次数: 3
Prevalence of Hypertension and Its Influencing Factors among Residents from Erqi District in Zhengzhou 郑州市二七区居民高血压患病率及影响因素分析
Q3 Medicine Pub Date : 2017-11-01 DOI: 10.3969/J.ISSN.1007-9572.2017.00.124
Yingying Song, Y. Wan, Shanshan Ma, T. Sun, Yu Wang, R. Wang, Kuiyuan Du, Z. Ren, F. Guan, Bo Yang
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引用次数: 0
期刊
中国全科医学
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