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Endarterectomía carotídea: revisión de 10 años de práctica de la anestesia general y locorregional en un hospital terciario en Portugal 颈动脉内膜切除术:回顾葡萄牙一家三级医院10年全身麻醉和局部麻醉的实践
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2014.03.012
Mercês Lobo, Joana Mourão, Graça Afonso

Background

Retrospective and prospective randomized studies have compared general and locoregional anesthesia for carotid endarterectomy, but without definitive results.

Objectives

Evaluate the incidence of complications (medical, surgical, neurological, and hospital mortality) in a tertiary center in Portugal and review the literature.

Method

Retrospective analysis of patients undergoing endarterectomy between 2000 and 2011, using a software for hospital consultation.

Results

A total of 750 patients were identified, and locoregional anesthesia had to be converted to general anesthesia in 13 patients. Thus, a total of 737 patients were included in this analysis: 74% underwent locoregianal anesthesia and 26% underwent general anesthesia. There was no statistically significant difference between the 2 groups regarding perioperative variables. The use of shunt was more common in patients undergoing general anesthesia, a statistically significant difference. The difference between groups of strokes and mortality was not statistically significant. The average length of stay was shorter in patients undergoing locoregional anesthesia with a statistically significant difference.

Conclusions

We found that our data are overlaid with the literature data. After reviewing the literature, we found that the number of studies comparing locoregional and general anesthesia and its impact on delirium, cognitive impairment, and decreased quality of life after surgery is still very small and can provide important data to compare the 2 techniques. Thus, some questions remain open, which indicates the need for randomized studies with larger number of patients and in new centers.

背景:回顾性和前瞻性随机研究比较了全身麻醉和局部麻醉在颈动脉内膜切除术中的应用,但没有明确的结果。目的评估葡萄牙某三级医疗中心的并发症(内科、外科、神经内科和住院死亡率)发生率,并回顾相关文献。方法回顾性分析2000 ~ 2011年行动脉内膜切除术的患者,采用医院会诊软件。结果750例患者中有13例由局部麻醉转为全身麻醉。因此,共有737例患者被纳入本分析:74%接受局部区域麻醉,26%接受全身麻醉。两组围手术期各项指标差异无统计学意义。在接受全身麻醉的患者中,分流器的使用更为常见,差异有统计学意义。中风和死亡率组间差异无统计学意义。局区域麻醉患者的平均住院时间较短,差异有统计学意义。结论我们发现我们的数据与文献数据重叠。在回顾文献后,我们发现比较局部麻醉和全身麻醉及其对谵妄、认知障碍和术后生活质量下降影响的研究数量仍然很少,可以为比较两种技术提供重要的数据。因此,一些问题仍未解决,这表明需要在新的中心进行大量患者的随机研究。
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引用次数: 1
Bloqueo paravertebral ecoguiado para la piloromiotomía en 3 neonatos con estenosis hipertrófica de píloro congénita 生态引导椎旁阻滞在3例新生儿先天性肥厚性幽门狭窄的幽门切开术中的应用
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2014.03.010
Javier Mata-Gómez, Rosana Guerrero-Domínguez, Marta García-Santigosa, Antonio Ontanilla

Background and objectives

Hypertrophic pyloric stenosis is a relatively common affection of gastrointestinal tract in childhood that results in symptoms, such as projectile vomiting and metabolic disorders that imply a high risk of aspiration during anesthetic induction. In this way, the carrying out of a technique with general anesthesia and intravenous rapid sequence induction, preoxygenation and cricoid pressure are recommended. After the correction of systemic metabolic alkalosis and pH normalization, cerebrospinal fluid can keep a state of metabolic alkalosis. This circumstance, in addition to the residual effect of neuromuscular blocking agents, inhalant anesthetics and opioids could increase the risk of postoperative apnea after a general anesthesia.

Case report

We present the successful management in 3 neonates in those a pyloromyotomy was carried out because they had presented congenital hypertrophic pyloric stenosis. This procedure was done under general anesthesia with orotracheal intubation and rapid sequence induction. Then, ultrasound-guided paravertebral block was performed as analgesic method without the need for administrating opioids within intraoperative period and keeping an appropriate analgesic level.

Conclusions

Local anesthesia has demonstrated to be safe and effective in pediatric practice. We consider the ultrasound-guided paravertebral block with one dose as a possible alternative for other local techniques described, avoiding the use of opioids and neuromuscular blocking agents during general anesthesia, and reducing the risk of central apnea within postoperative period.

背景和目的幽门肥厚性狭窄是儿童时期较为常见的胃肠道疾病,其症状包括抛射性呕吐和代谢紊乱,这意味着麻醉诱导过程中有较高的吸入性风险。因此,建议采用全麻、静脉快速序列诱导、预充氧和环状软骨压术。经全身代谢性碱中毒纠正及pH值正常化后,脑脊液可保持代谢性碱中毒状态。在这种情况下,除了神经肌肉阻滞剂的残留作用外,吸入性麻醉剂和阿片类药物也会增加全麻术后呼吸暂停的风险。病例报告:我们报告了3例因先天性肥厚性幽门狭窄而行幽门切开术的新生儿的成功治疗。该手术在全身麻醉下进行,经口气管插管和快速序贯诱导。然后,超声引导下椎旁阻滞作为镇痛方法,术中无需给药阿片类药物,并保持适当的镇痛水平。结论局部麻醉在儿科实践中是安全有效的。我们认为超声引导下的单剂量椎旁阻滞可以替代其他局部技术,避免在全身麻醉时使用阿片类药物和神经肌肉阻断剂,并降低术后中枢性呼吸暂停的风险。
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引用次数: 0
Bienestar ocupacional en anestesistas: su relación con la metodología educativa 麻醉师的职业幸福感:与教育方法的关系
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2015.05.001
Pratyush Gupta, Roger Moore, Gastão F. Duval Neto
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引用次数: 0
Utilización del sugammadex en el paciente quemado: estudio descriptivo sugammadex在烧伤患者中的应用:描述性研究
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2014.10.001
Eduardo Rodríguez Sánchez M., Concepción Martínez Torres, Pablo Herrera Calo, Ignacio Jiménez

Objectives

The burn patient is a challenge for the anesthesiologist, undergoing several surgeries during admission, and requiring general anesthesia and muscle relaxation most of the times. They have respiratory system impairment and a response to muscle relaxants that differs from the healthy patient, thus proper monitoring and reversal is crucial. We analyzed sugammadex effectiveness and safety in this population.

Material and methods

Prospectively descriptive study including 4 patients, all of them considered major burn patients, who underwent escharotomy with general anesthesia and neuromuscular relaxation. The main variable was the time for recovery of a TOF higher than 0.9 after the administration of sugammadex before extubation.

Results

Mean time of recovery from a TOF ratio higher than 0.9 following the administration of Sugammadex was of 4.95 min 95% CI (3.25-6.64, P = .53);

Conclusions

the reversion of neuromuscular relaxation with sugammadex appears to be effective and safe in the burn patient. More analytical, comparative studies, of larger populations would be necessary to confirm this data.

目的烧伤患者对麻醉医师来说是一个挑战,入院期间需要进行多次手术,并且大多数时候需要全身麻醉和肌肉放松。他们有呼吸系统损伤,对肌肉松弛剂的反应与健康患者不同,因此适当的监测和逆转是至关重要的。我们分析了sugammadex在该人群中的有效性和安全性。材料与方法前瞻性描述性研究4例重度烧伤患者,在全身麻醉和神经肌肉松弛下行巩膜切开术。主要变量为拔管前给药后TOF大于0.9的恢复时间。结果在TOF比大于0.9的烧伤患者中,使用Sugammadex后平均恢复时间为4.95 min, 95% CI (3.25 ~ 6.64, P = 0.53);结论在烧伤患者中,使用Sugammadex恢复神经肌肉松弛是有效且安全的。为了证实这一数据,需要对更大的人口进行更多的分析和比较研究。
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引用次数: 0
Anafilaxia perioperatoria Anafilaxia perioperatoria
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2014.09.002
Marta Inés Berrío Valencia

Background and objective

Anaphylaxis remains one of the potential causes of perioperative death, being generally unanticipated and quickly progress to a life threatening situation. A narrative review of perioperative anaphylaxis is performed.

Content

The diagnostic tests are primarily to avoid further major events. The mainstays of treatment are adrenaline and intravenous fluids.

Conclusion

The anesthesiologist should be familiar with the proper diagnosis, management and monitoring of perioperative anaphylaxis.

背景与目的过敏反应仍然是围手术期死亡的潜在原因之一,通常是意料之外的,并迅速发展到危及生命的情况。对围手术期过敏反应进行叙述性回顾。诊断测试主要是为了避免进一步的重大事件。治疗的主要手段是肾上腺素和静脉输液。结论麻醉医师应熟悉围手术期过敏反应的正确诊断、处理和监测。
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引用次数: 0
Comparación de los efectos profilácticos del droperidol y del ondansetrón sobre el prurito provocado por la morfina subaracnoidea droperidol和ondansetron对蛛网膜下腔吗啡引起的瘙痒的预防作用的比较
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2013.11.006
Fabio Ferreira da Cunha Brião , Marcio Leal Horta , Bernardo Lessa Horta , Guilherme Antônio Moreira de Barros , Ana Paula Behrensdorf , Ingrid Severo , Mariana Antunes Nunes , Roberta Boabaid , André Real

Background and objectives

The prophylactic effect of ondansetron on subarachnoid morphine-induced pruritus is controversial, while evidence suggests that droperidol prevents pruritus. The aim of this study is to compare the effects of droperidol and ondansetron on subarachnoid morphine-induced pruritus.

Methods

One hundred eighty patients ASA I or II patients scheduled to undergo cesarean sections under subarachnoid anesthesia combined with morphine 0.2 mg were randomized to receive, after the child's birth, metoclopramide 10 mg (Group I-control), droperidol 2.5 mg (Group II) or ondansetron 8 mg (Group III). Postoperatively, the patients were assessed for pruritus (absent, mild, moderate or severe) or other side effects by blinded investigators. Patients were also blinded to their group allocation. The tendency to present more severe forms of pruritus was compared between groups. NNT was also determined.

Results

Patients assigned to receive droperidol (proportional odds ratio: 0.45 [95% confidence interval 0.23-0.88]) reported less pruritus than those who received metoclopramide. Ondansetron effect was similar to metoclopramide (proportional odds ratio: 0.95 [95% confidence interval 0.49-1.83]). The NNT for droperidol and ondansetron was 4.0 and 14.7, respectively.

Conclusions

Ondansetron does not inhibit subarachnoid morphine-induced pruritus.

背景与目的昂丹西琼对蛛网膜下腔吗啡引起的瘙痒的预防作用尚存争议,而有证据表明氟哌啶醇可以预防瘙痒。本研究的目的是比较哌啶醇和昂丹西琼对蛛网膜下腔吗啡引起的瘙痒的影响。方法180例ASA I级或II级患者拟行蛛网膜下腔麻醉联合吗啡0.2 mg剖宫产术,分娩后随机给予甲氧氯普胺10 mg(对照组)、哌啶醇2.5 mg(组)或昂丹司琼8 mg(组)。术后采用盲法评估患者瘙痒(无、轻、中、重度)及其他不良反应。患者也不知道他们的分组分配。比较两组之间出现更严重形式的瘙痒的趋势。NNT也被确定。结果接受哌啶醇治疗的患者(比例优势比:0.45[95%可信区间0.23-0.88])瘙痒症状少于接受甲氧氯普胺治疗的患者。昂丹司琼效应与甲氧氯普胺相似(比例优势比:0.95[95%可信区间0.49-1.83])。氟哌啶醇和昂丹司琼的NNT分别为4.0和14.7。结论sondansetron对蛛网膜下腔吗啡性瘙痒无抑制作用。
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引用次数: 1
Hematoma subdural bilateral secundario a punción dural accidental 双侧继发性硬脑膜下血肿punción硬脑膜意外
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2014.07.001
Sofía Ramírez, Elena Gredilla, Blanca Martínez, Fernando Gilsanz

We report the case of a 25-year-old woman, who received epidural analgesia for labour pain and subsequently presented post-dural puncture headache. Conservative treatment was applied and epidural blood patch was performed. In the absence of clinical improvement and due to changes in the postural component of the headache, a brain imaging test was performed showing a bilateral subdural hematoma.

The post-dural puncture headache is relatively common, but the lack of response to established medical treatment as well as the change in its characteristics and the presence of neurological deficit, should raise the suspicion of a subdural hematoma, which although is rare, can be lethal if not diagnosed and treated at the right time.

我们报告的情况下,一个25岁的妇女,谁接受硬膜外镇痛分娩疼痛,随后提出后硬膜穿刺头痛。保守治疗,硬膜外补血。在没有临床改善的情况下,由于头痛的体位成分的变化,进行了脑成像检查,显示双侧硬膜下血肿。硬脑膜穿刺后头痛相对常见,但对现有药物治疗缺乏反应,以及其特征的变化和神经功能缺损的存在,应引起对硬脑膜下血肿的怀疑,这种血肿虽然罕见,但如果不及时诊断和治疗,可能是致命的。
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引用次数: 2
Eficacia analgésica del bloqueo del plano transverso del abdomen ecoguiado-revisión sistemática 超声引导腹部横平面阻滞的镇痛效果-系统综述
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2013.10.015
Javier Ripollés , Sandra Marmaña Mezquita , Alfredo Abad , José Calvo

Background

The transverse abdominal plan blockade (TAP) is a block of abdominal wall that has diffused rapidly in the clinical practice as part of a multimodal analgesia for abdominal surgery. The performance of the ultrasound-guided technique has allowed the lowering of potential complications, as well as new approaches that according to the descriptions carried out and the prospective studies would make it possible to utilize the TAP in different surgical interventions; however, the results obtained in randomized clinical trials (RCTs) are inconsistent.

Objectives

To prepare a systematic review aiming to determine the efficacy of the ultrasound-guided TAP for different surgical interventions, as well as the indications according to the approaches and their influences.

Methods

Two research approaches, one manual, and the other in Pubmed returned 28 RCT where intervention with ultrasound-guided TAP were performed to compare the analgesic efficacy in contrast to another technique in adults, published between 2007 and October 2013, in English or Spanish, with Jadad score >1, according to the inclusion criteria for this review. The authors analyzed independently all the RCT.

Conclusions

The TAP have been shown to be an effective technique in colorectal surgery, cesarean section, cholecystectomy, hysterectomy, appendectomy, donor nephrectomy, retropubic prostatectomy, and bariatric surgery. However, the data found in RCT are not conclusive, and as a result, it is necessary to develop new and well designed RCT, with enough statistical power to compare different approaches, drugs, doses, and volumes for the same intervention, aiming to answer the current questions and their effects in the habitual clinical practice.

背景横腹平面阻滞术(TAP)是一种腹壁阻滞,在临床实践中作为腹部手术多模式镇痛的一部分已迅速扩散。超声引导技术的性能允许降低潜在的并发症,以及新的方法,根据进行的描述和前瞻性研究将使TAP在不同的手术干预中使用成为可能;然而,在随机临床试验(RCTs)中获得的结果不一致。目的探讨超声引导下TAP在不同手术方式下的疗效,以及不同手术方式的适应证及其影响。方法两种研究方法,一种是手册,另一种是Pubmed中返回的28项随机对照试验,其中超声引导下的TAP进行干预,比较与另一种成人技术的镇痛效果,根据本综述的纳入标准,2007年至2013年10月发表的英文或西班牙语,Jadad评分为1。作者独立分析了所有的随机对照试验。结论TAP在结直肠手术、剖宫产、胆囊切除术、子宫切除术、阑尾切除术、供肾切除术、耻骨后前列腺切除术和减肥手术中是一种有效的技术。然而,在RCT中发现的数据并不具有结论性,因此,有必要开发新的和设计良好的RCT,具有足够的统计能力来比较相同干预的不同方法,药物,剂量和体积,旨在回答当前的问题及其在习惯性临床实践中的效果。
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引用次数: 2
Una pregunta sobre ropivacaína para la raquianestesia unilateral: solución hipobárica 关于罗哌卡因用于单侧脊髓麻醉的问题:低压氧溶液
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2014.02.015
Da-Qiang Zhao
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引用次数: 0
Manejo anestésico para la cirugía de atresia de esófago en un neonato con síndrome de Goldenhar Goldenhar综合征新生儿食道闭锁手术的麻醉处理
Pub Date : 2015-07-01 DOI: 10.1016/j.bjanes.2013.07.013
Rosana Guerrero-Domínguez , Daniel López-Herrera-Rodríguez , Inmaculada Benítez-Linero , Antonio Ontanilla

Background and objectives

Goldenhar's syndrome is a polymalformative condition consisting of a craniofacial dysostosis that determines difficult airway in up to 40% of cases. We described a case of a newborn with Goldenhar's syndrome with esophageal atresia and tracheoesophageal fistula who underwent repair surgery.

Case report

We report the case of a 24-hour-old newborn with Goldenhar's syndrome. He had esophageal atresia with distal tracheoesophageal fistula. It was decided that an emergency surgery would be performed for repairing it. It was carried out under sedation, intubation with fibrobronchoscope distal to the fistula, to limit the air flow into the esophagus, and possible abdominal distension. Following complete repair of the esophageal atresia and fistula ligation, the patient was transferred to the intensive care unit and intubated under sedation and analgesia.

Conclusions

The finding of a patient with Goldenhar's syndrome and esophageal atresia assumes an exceptional situation and a challenge for anesthesiologists, since the anesthetic management depends on the patient comorbidity, the type of tracheoesophageal fistula, the usual hospital practice and the skills of the anesthesiologist in charge, with the main peculiarity being maintenance of adequate pulmonary ventilation in the presence of a communication between the airway and the esophagus. Intubation with fibrobronchoscope distal to the fistula deals with the management of a probably difficult airway and limits the passage of air to the esophagus through the fistula.

背景和目的戈登哈氏综合征是一种多畸形疾病,包括颅面发育不全,高达40%的病例导致气道困难。我们描述了一个新生儿与戈登哈综合征食管闭锁和气管食管瘘谁接受修复手术。病例报告我们报告一例24小时出生的新生儿与戈登哈氏综合征。食管闭锁伴远端气管食管瘘。最后决定进行紧急手术来修复它。该手术是在镇静下进行的,在瘘远端的纤维支气管镜插管,以限制空气流入食管,并可能出现腹胀。在完全修复食管闭锁和瘘管结扎后,患者被转移到重症监护病房,在镇静和镇痛下插管。结论:戈登哈氏综合征合并食管闭锁患者的发现是一种特殊的情况,对麻醉师来说是一个挑战,因为麻醉管理取决于患者的合并症、气管食管瘘的类型、通常的医院实践和负责的麻醉师的技能,主要特点是在气道和食管之间存在通信的情况下维持适当的肺通气。在瘘管远端的纤维支气管镜下插管处理可能困难的气道,并限制空气通过瘘管进入食管。
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引用次数: 0
期刊
Brazilian Journal of Anesthesiology (Edicion en Espanol)
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