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Effects of Various Processing Parameters on Mechanical Properties and Biocompatibility of Fe-based Bulk Metallic Glass Processed via Selective Laser Melting at Constant Energy Density 不同工艺参数对恒能量密度激光熔融法制备铁基大块金属玻璃力学性能和生物相容性的影响
Pub Date : 2022-09-01 DOI: 10.1016/j.cjmeam.2022.100038
Niyou Wang , Shuai Chang , Guiwei Li , S Thameem Dheen , A Senthil Kumar , Wenzheng Wu , Qingping Liu , Ji Zhao , Luquan Ren , Jerry Ying Hsi Fuh

The unique properties of bulk metallic glass (BMG) render it an excellent material for bone-implant applications. BMG samples are difficult to produce directly because of the critical cooling rate of molding. Advancements in additive manufacturing technologies, such as selective laser melting (SLM), have enabled the development of BMG. The successful production of materials via SLM relies significantly on the processing parameters; meanwhile, the overall energy density affects the crystallization and, thus, the final properties. Therefore, to further determine the effects of the processing parameters, SLM is performed in this study to print Fe-based BMG with different properties three dimensionally using selected processing parameters but a constant energy density. The printed amorphous Fe-based BMG outperforms the typical 316 L stainless steel (316 L SS) in terms of mechanical properties and corrosion resistance. Moreover, observations from nanoindentation tests indicate that the hardness and elastic modulus of the Fe-based BMG can be customized explicitly by adjusting the SLM processing parameters. Indirect cytotoxicity results show that the Fe-based BMG can enhance the viability of SAOS2 cells, as compared with 316 L SS. These intriguing results show that Fe-based BMG should be investigated further for orthopedic implant applications.

大块金属玻璃(BMG)的独特性能使其成为骨植入应用的优良材料。由于成型的临界冷却速率,BMG样品很难直接生产。选择性激光熔化(SLM)等增材制造技术的进步促进了BMG的发展。通过SLM成功生产材料在很大程度上依赖于加工参数;同时,总能量密度影响结晶,从而影响最终性能。因此,为了进一步确定工艺参数的影响,本研究采用SLM方法,在一定能量密度下,选择一定的工艺参数,对不同性能的铁基BMG进行三维打印。打印的非晶铁基BMG在机械性能和耐腐蚀性方面优于典型的316 L不锈钢(316 L SS)。此外,纳米压痕试验结果表明,铁基BMG的硬度和弹性模量可以通过调整SLM工艺参数来明确定制。间接细胞毒性结果表明,与316 L SS相比,铁基BMG可以提高SAOS2细胞的活力。这些有趣的结果表明,铁基BMG应该进一步研究其在骨科植入物中的应用。
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引用次数: 2
Interfacial Characteristics and Formation Mechanisms of Copper–steel Multimaterial Structures Fabricated via Laser Powder Bed Fusion Using Different Building Strategies 不同构建策略下激光粉末床熔敷铜-钢复合材料结构的界面特性及形成机理
Pub Date : 2022-09-01 DOI: 10.1016/j.cjmeam.2022.100045
Linqing Liu , Di Wang , Guowei Deng , Yongqiang Yang , Jie Chen , Jinrong Tang , Yonggang Wang , Yang Liu , Xusheng Yang , Yicha Zhang

Laser powder bed fusion (LPBF) is an innovative method for manufacturing multimaterial components with high geometrical resolution. The LPBF-printing sequences of materials may be diverse in the actual design and application of multimaterial components. In this study, multimaterial copper (CuSn10)–steel (316 L) structures are printed using different building strategies (printing 316 L on CuSn10 and printing CuSn10 on 316 L) via LPBF, and the characteristics of two interfaces (the 316 L/CuSn10 or “L/C” and CuSn10/316 L or “C/L” interfaces) are investigated. Subsequently, the interfacial melting mode and formation mechanisms are discussed. At the L/C interface, the keyhole melting mode induced by the high volumetric energy density (EL/C = 319.4 J/mm3) results in a large penetration depth in the pre-solidified layer and enhances laser energy absorption, thus promoting the extensive migration of materials and intense intermixing of elements to form a wide diffusion zone (∼400 μm). At the C/L interface, the conduction mode induced by the low volumetric energy density (EC/L = 74.1 J/mm3) results in a narrow diffusion zone (∼160 μm). The interfacial defects observed are primarily cracks and pores. More cracks appeared at the C/L interface, which is attributable to the weak bonding strength of the narrow diffusion zone. This study provides guidance and reference for the design and manufacturing of multimaterial components via LPBF using different building strategies.

激光粉末床熔融是一种制造高几何分辨率多材料部件的新方法。在多材料部件的实际设计和应用中,材料的lpbf打印顺序可能是多种多样的。在本研究中,采用不同的构建策略(在CuSn10上打印316l和在316l上打印CuSn10)通过LPBF打印多材料铜(CuSn10) -钢(316l)结构,并研究了两种界面(316l /CuSn10或“L/C”和CuSn10/316 L或“C/L”界面)的特性。讨论了界面熔融模式和形成机理。在L/C界面处,高体积能量密度(EL/C = 319.4 J/mm3)诱导的锁孔熔化模式使预固化层穿透深度大,增强了激光能量吸收,促进了材料的广泛迁移和元素的强烈混合,形成宽扩散区(~ 400 μm)。在C/L界面,低体积能量密度(EC/L = 74.1 J/mm3)诱导的传导模式导致了一个狭窄的扩散区(~ 160 μm)。观察到的界面缺陷主要是裂纹和气孔。在C/L界面处出现较多裂纹,这是由于窄扩散区结合强度较弱所致。本研究为采用不同建造策略的LPBF多材料构件的设计和制造提供了指导和参考。
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引用次数: 6
A Review on Distortion and Residual Stress in Additive Manufacturing 增材制造中的畸变和残余应力研究进展
Pub Date : 2022-09-01 DOI: 10.1016/j.cjmeam.2022.100039
Deqiao Xie , Fei Lv , Youwen Yang , Lida Shen , Zongjun Tian , Cijun Shuai , Bo Chen , Jianfeng Zhao

Additive manufacturing (AM) has gained extensive attention and tremendous research due to its advantages of fabricating complex-shaped parts without the need of casting mold. However, distortion is a known issue for many AM technologies, which decreases the precision of as-built parts. Like fusion welding, the local high-energy input generates residual stresses, which can adversely affect the fatigue performance of AM parts. To the best of the authors’ knowledge, a comprehensive review does not exist regarding the distortion and residual stresses dedicated for AM, despite some work has explored the interrelationship between the two. The present review is aimed to fill in the identified knowledge gap, by first describing the evolution of distortion and residual stresses for a range of AM processes, and second assessing their influencing factors. This allows us to elucidate their formation mechanisms from both the micro- and macro-scales. Moreover, approaches which have been successfully adopted to mitigate both the distortion and residual stresses are reviewed. It is anticipated that this review paper opens many opportunities to increase the success rate of AM parts by improving the dimension precision and fatigue life.

增材制造(AM)以其无需浇铸模具即可加工复杂形状零件的优点得到了广泛的关注和大量的研究。然而,对于许多增材制造技术来说,变形是一个众所周知的问题,它会降低成品零件的精度。与熔焊一样,局部高能输入会产生残余应力,对增材制造零件的疲劳性能产生不利影响。据作者所知,尽管一些工作已经探讨了两者之间的相互关系,但关于AM专用的变形和残余应力的全面审查并不存在。本综述旨在通过首先描述一系列AM工艺的变形和残余应力的演变,然后评估其影响因素来填补已确定的知识空白。这使我们能够从微观和宏观两个尺度阐明它们的形成机制。此外,还回顾了已成功采用的减轻变形和残余应力的方法。期望本综述为通过提高尺寸精度和疲劳寿命来提高增材制造零件的成功率开辟了许多机会。
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引用次数: 22
3D Printed Ultra-thin Acoustic Metamaterials with Adaptable Low-frequency Absorption Performance 具有自适应低频吸收性能的3D打印超薄声学材料
Pub Date : 2022-09-01 DOI: 10.1016/j.cjmeam.2022.100036
Junxiang Fan , Lei Zhang , Xiaobo Wang , Zhi Zhang , Shuaishuai Wei , Bo Song , Aiguo Zhao , Xiao Xiang , Xuefeng Zhu , Yusheng Shi

The inherent absorption frequency of traditional sound absorbers makes it difficult to solve the problem of acoustic wave removal in a changeable acoustic environment. In this study, acoustic absorption metamaterials (AAMs) with adaptable sound absorption performance were innovatively designed using the structural combination concept and fabricated via 3D printing. Accordingly, two coiled-up channels were combined in a single cell, which could effectively broaden the absorption bandwidth in a limited space. The longitudinal movement of the coiled-up channels endowed the tunable entire depth and internal cavity of the AAMs; thus, the sound absorption performance could be tailored accordingly. Through computational analysis and experimental verification, it was demonstrated that the depth of the AAM could be adjusted from 10 mm to 20 mm, and the corresponding absorption frequencies of the two channels ranged from 206 Hz to 179 Hz and 379 Hz to 298 Hz, respectively. In addition, the finite element results also indicate that the sound absorption bandwidth of AAMs could be further improved by the periodic arrangement of the units. This work opens a promising structural design approach for presenting a route toward acoustic devices with adaptable absorption performances.

传统吸声器固有的吸声频率,使得在变化的声环境中难以解决声波的去除问题。本研究采用结构组合的概念,创新性地设计了具有自适应吸声性能的吸声超材料(AAMs),并通过3D打印技术制造。因此,将两个线圈通道组合在一个单元中,可以在有限的空间内有效地扩大吸收带宽。卷绕通道的纵向运动赋予了aam的整体深度和内部腔体可调;因此,吸声性能可以相应地调整。通过计算分析和实验验证,表明AAM的深度可在10 ~ 20 mm范围内调节,对应的两个通道的吸收频率分别为206 ~ 179 Hz和379 ~ 298 Hz。此外,有限元分析结果还表明,周期性布置可以进一步提高aam的吸声带宽。这项工作开辟了一种有前途的结构设计方法,为具有适应性吸收性能的声学器件提供了一条途径。
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引用次数: 3
Keyhole-induced Porosity in Laser Manufacturing Processes: Formation Mechanism and Dependence on Scan Speed 激光制造过程中锁眼诱导孔隙:形成机制及其与扫描速度的关系
Pub Date : 2022-09-01 DOI: 10.1016/j.cjmeam.2022.100044
R D Seidgazov, F Kh Mirzade

Laser welding and laser-based powder-bed fusion additive manufacturing in the deep penetration (keyhole) mode are promising technologies for the synthesis of metal components. The significant potential of these technologies remains latent because of structural defects (porosity), which significantly degrade the structural integrity and performance of the end products. Practical strategies for reducing those defects are addressed through fundamental understanding of their formation. In this study, pore formation of hydrodynamic origin is investigated, including the dynamics and mechanisms of the formation based on the above mentioned technologies. The pore volume and frequency of pore appearance, depending on the amplitude and frequency of capillary vibrations, are considered. Physical analysis is performed to obtain the scanning velocity values for the maximum and zero amplitudes and the frequency of capillary waves. A comparison between calculated curves and experimental data confirms both the capillary origin of the pores and the estimated scanning speeds at which the parameters of the pores exhibit their maximum values or vanish. The results obtained may facilitate in the selection of the optimal scanning speed when designing a pore-free technology.

激光焊接和基于激光粉末床的深熔(锁孔)模式的增材制造是一种很有前途的金属部件合成技术。这些技术的巨大潜力仍然是潜在的,因为结构缺陷(孔隙),这大大降低了最终产品的结构完整性和性能。减少这些缺陷的实际策略是通过对其形成的基本理解来解决的。在本研究中,研究了水动力成因的孔隙形成,包括基于上述技术的孔隙形成动力学和机制。考虑了孔隙体积和孔隙出现的频率,这取决于毛细管振动的振幅和频率。通过物理分析得到了毛细波的最大振幅和零振幅的扫描速度值和频率。计算曲线与实验数据的对比证实了孔隙的毛细管起源和孔隙参数达到最大值或消失的估计扫描速度。所得结果可为设计无孔扫描工艺时选择最佳扫描速度提供参考。
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引用次数: 0
Additive Manufacturing of Hydroxyapatite Bioceramic Scaffolds with Projection Based 3D Printing 投影3D打印羟基磷灰石生物陶瓷支架的增材制造
Pub Date : 2022-06-01 DOI: 10.1016/j.cjmeam.2022.100021
Huifeng Shao , Zhiheng Nian , Zhuoluo Jing , Tao Zhang , Jiahua Zhu , Xiang Li , Youping Gong , Yong He

Hydroxyapatite (HA) bioceramics have garnered considerable attention owing to their applications in the field of bone repair and excellent biocompatibility. Compared to extrusion-based 3D printing, projection-based 3D printing (3DPP) can fabricate parts with complex geometry, high accuracy, and efficiency, which is very promising for bioceramic scaffolds. However, conventional 3DPP using a paste with low viscosity will cause severe shrinkage of the parts after sintering, which makes it unsuitable for bioceramic scaffolds, and a system investigation of the printing process remains insufficient. In this study, we proposed a 3DPP device suitable for bioceramic scaffolds and investigated the additive manufacturing of HA scaffolds. Ceramic paste properties and process parameters of curing, debinding, and sintering were initially examined. The mechanical properties, shrinkage, and biocompatibility in vitro of the sintered samples were further investigated. The obtained results indicate that HA bioceramics with uniform morphology, complex structure, and high accuracy can be manufactured using the 3DPP equipment. HA scaffolds have the mechanical strength of human cancellous bone, while HA scaffolds cultured with osteoblast precursor cells possess strong biocompatibility and can promote osteoblast adhesion, proliferation, and differentiation. These results suggest a promising application of the 3DPP technique in the preparation of bioceramic scaffolds, and the HA scaffolds fabricated using the 3DPP technique exhibit promising potential in fulfilling a constructive role in the biomedical field of human bone regeneration repair.

羟基磷灰石(Hydroxyapatite, HA)生物陶瓷因其在骨修复领域的应用和良好的生物相容性而备受关注。与基于挤压的3D打印相比,基于投影的3D打印(3DPP)可以制造复杂几何形状的零件,精度高,效率高,这对于生物陶瓷支架来说是非常有前途的。然而,传统3DPP使用的黏度较低的浆料在烧结后会造成零件严重的收缩,不适合用于生物陶瓷支架,对打印工艺的系统研究仍然不足。本研究提出了一种适用于生物陶瓷支架的3DPP装置,并对羟基磷灰石支架的增材制造进行了研究。初步考察了陶瓷浆料的性能及固化、脱脂、烧结等工艺参数。进一步研究了烧结样品的力学性能、收缩率和体外生物相容性。结果表明,利用该设备可以制备出形貌均匀、结构复杂、精度高的HA生物陶瓷。HA支架具有人松质骨的机械强度,而与成骨前体细胞培养的HA支架具有较强的生物相容性,可促进成骨细胞粘附、增殖和分化。这些结果表明3DPP技术在制备生物陶瓷支架方面具有广阔的应用前景,利用3DPP技术制备的透明质酸支架在人骨再生修复等生物医学领域具有广阔的应用前景。
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引用次数: 8
Spiral-eutectic-reinforced Biodegradable Zn–Mg–Ag Alloy Prepared via Selective Laser Melting 选择性激光熔化法制备螺旋共晶增强可生物降解Zn-Mg-Ag合金
Pub Date : 2022-06-01 DOI: 10.1016/j.cjmeam.2022.100022
Chengde Gao , Chuanzhi Li , Shuping Peng , Cijun Shuai

Zn is a promising biodegradable metal owing to its moderate degradation rate and acceptable biocompatibility. However, the insufficient mechanical strength and plasticity of pure Zn limits its application in bone implants. In this study, a spiral eutectic structure is constructed in Zn–Mg–Ag alloys prepared via selective laser melting to improve their mechanical properties. Results show that the prepared Zn–Mg–Ag alloys are composed of a primary Zn matrix and a eutectic phase, which is composed of alternating α-Zn and an intermetallic compound, MgZn2. Moreover, the eutectic phase resembles a spiral and increases with Ag content in the alloys. The eutectic pinning effect hinders dislocation and hence results in dislocation accumulation. Meanwhile, the spiral structure alters the propagation direction and dissipates the propagation energy of cracks layer by layer. Consequently, a compressive strength of up to 309 ± 15 MPa and an improved strain of 27% are exhibited in Zn–3Mg–1Ag alloy. Moreover, the Zn–Mg–Ag alloys show high biocompatibility with MG-63 cells and antibacterial activity against Escherichia coli. These findings indicate the potential of spiral eutectic structures for enhancing both the mechanical strength and plasticity of biodegradable Zn alloys.

锌具有中等降解率和良好的生物相容性,是一种很有前途的生物降解金属。但纯锌的机械强度和塑性不足,限制了其在骨种植体中的应用。在本研究中,通过选择性激光熔化法制备的Zn-Mg-Ag合金形成螺旋共晶结构,以改善其力学性能。结果表明:制备的Zn - mg - ag合金由初生Zn基体和α-Zn与金属间化合物MgZn2交替组成的共晶相组成;共晶相呈螺旋状,随合金中Ag含量的增加而增加。共晶钉住效应阻碍位错,从而导致位错积累。同时,螺旋结构改变了裂纹的扩展方向,使裂纹的扩展能量逐层耗散。结果表明,Zn-3Mg-1Ag合金的抗压强度可达309±15 MPa,应变提高27%。此外,Zn-Mg-Ag合金与MG-63细胞具有良好的生物相容性和抑菌活性。这些发现表明螺旋共晶结构在提高生物可降解锌合金的机械强度和塑性方面具有潜力。
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引用次数: 5
Construction and Application of in vitro Alveolar Models Based on 3D Printing Technology 基于3D打印技术的体外肺泡模型构建及应用
Pub Date : 2022-06-01 DOI: 10.1016/j.cjmeam.2022.100025
Tiankun Liu , Chang Zhou , Yongchun Shao , Zhuo Xiong , Ding Weng , Yuan Pang , Wei Sun

Increasing lung diseases, mutating coronaviruses, and the development of new compounds urgently require biomimetic in vitro lung models for lung pathology, toxicology, and pharmacology. The current construction strategies for lung models mainly include animal models, 2D cell culture, lung-on-a-chip, and lung organoids. However, current models face difficulties in reproducing in vivo-like alveolar size and vesicle-like structures, and are unable to contain multiple cell types. In this study, a strategy for constructing alveolar models based on degradable hydrogel microspheres is proposed. Hydrogel microspheres, 200–250 µm in diameter, were prepared using a self-developed printing technique driven by alternating viscous and inertial forces. Microcapsules were further constructed using a coacervation-based layer-by-layer technique and core liquefaction. Three types of cells were inoculated and co-cultured on hydrogel capsules based on optimized microcapsule surface treatment strategies. Finally, an in vitro three-dimensional endothelial alveolar model with a multicellular composition and vesicle-like structure with a diameter of approximately 230 µm was successfully constructed. Cells in the constructed alveolar model maintained a high survival rate. The LD50 values of glutaraldehyde based on the constructed models were in good agreement with the reference values, validating the potential of the model for future toxicant and drug detection.

肺部疾病的增加、冠状病毒的变异以及新化合物的开发迫切需要体外仿生肺模型来进行肺病理、毒理学和药理学研究。目前肺模型的构建策略主要包括动物模型、二维细胞培养、肺芯片、肺类器官等。然而,目前的模型在复制体内样肺泡大小和囊泡样结构方面存在困难,并且无法包含多种细胞类型。本研究提出了一种基于可降解水凝胶微球构建肺泡模型的策略。采用自行开发的打印技术,在粘性和惯性力交替驱动下制备了直径为200-250µm的水凝胶微球。利用基于凝聚的逐层技术和核心液化进一步构建微胶囊。根据优化后的微胶囊表面处理策略,将3种类型的细胞接种在水凝胶胶囊上共培养。最后,成功构建了直径约230µm、具有多细胞组成和囊泡样结构的体外三维内皮肺泡模型。在构建的肺泡模型中,细胞保持了较高的存活率。基于所构建模型的戊二醛LD50值与参考值吻合较好,验证了该模型在未来毒物和药物检测中的潜力。
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引用次数: 1
Preparation, Microstructure, and Properties of ZrO2(3Y)/Al2O3 Bioceramics for 3D Printing of All-ceramic Dental Implants by Vat Photopolymerization ZrO2(3Y)/Al2O3生物陶瓷的制备、微观结构和性能研究
Pub Date : 2022-06-01 DOI: 10.1016/j.cjmeam.2022.100023
Lizheng Zhang, Hao Liu, H. Yao, Yong Zeng, Jimin Chen
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引用次数: 12
Spiral-eutectic-reinforced Biodegradable Zn–Mg–Ag Alloy Prepared via Selective Laser Melting 选择性激光熔化法制备螺旋共晶增强可生物降解Zn-Mg-Ag合金
Pub Date : 2022-06-01 DOI: 10.1016/j.cjmeam.2022.100022
Chengde Gao, C. Li, S. Peng, C. Shuai
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引用次数: 7
期刊
Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers
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