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COVID-19 disease: perspectives in low- and middle-income countries COVID-19疾病:低收入和中等收入国家的观点
Pub Date : 2020-07-01 DOI: 10.1016/j.intcar.2020.100005
Chris Carter, Nguyen Thi Lan Anh, Joy Notter

Pandemics such as COVID - 19 bring significant challenges for all health services, especially those in low-to low-middle income countries, where access to supplement and expand services may be difficult. For these countries with a limited workforce the loss of key workers to the illness itself or the need to self-isolate following contact can paralyse service delivery. This article looks at some of the issues that may arise and strategies to overcome them. It includes a case study from Viet Nam illustrating the need for a rapid integrated response to contact and prevent further outbreaks. Caring for COVID - 19 patients is a heavily dependent on the skills and expertise of the nurses. There is therefore a need to share nursing interventions that can be implemented without major resource implications in all hospital departments.

COVID - 19等大流行病给所有卫生服务带来了重大挑战,特别是在低收入和中低收入国家,在这些国家,获得补充和扩大服务可能很困难。对于这些劳动力有限的国家来说,关键工作人员因疾病本身而死亡或在接触后需要自我隔离,都可能使服务提供瘫痪。本文着眼于可能出现的一些问题以及克服这些问题的策略。报告包括越南的一项案例研究,说明有必要对接触采取快速综合反应并防止进一步暴发。照顾COVID - 19患者在很大程度上依赖于护士的技能和专业知识。因此,有必要分享在所有医院部门实施的护理干预措施,而不会产生重大的资源影响。
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引用次数: 18
Medication management in older adults 老年人的药物管理
Pub Date : 2020-07-01 DOI: 10.1016/j.intcar.2020.100002
Arduino A. Mangoni, Elzbieta A. Jarmuzewska

Older adults, the largest medication consumer group worldwide, are virtually excluded from participating in clinical trials that investigate the efficacy and safety of drugs. The consequent lack of robust evidence regarding the effects of medicines in the older population is concerning in view of the ever-increasing medication exposure and the high risk of adverse drug reactions (ADRs) in this group. Furthermore, a number of age-related alterations in pharmacokinetics and the inter-individual variability in homeostatic capacity suggest caution when translating the evidence from trials conducted in younger and healthier participants into the routine management of older patients. Several decision tools have been developed to prevent inappropriate prescribing and polypharmacy in older adults; however, additional research is warranted to justify their widespread clinical use. The role of traditional disease-centered end points, based on objective markers of response, might also need revisiting and complementation with measures of self-rated health, particularly in older patients who may also be frail or have a poor quality of life. This article provides an overview of medication management in older adults, particularly in relation with trends in prescribing, polypharmacy and inappropriate medication use, and the development of decision tools that might facilitate an individualized therapeutic plan in this group.

老年人是世界上最大的药物消费群体,他们实际上被排除在调查药物有效性和安全性的临床试验之外。鉴于老年人群中不断增加的药物暴露和药物不良反应(adr)的高风险,因此缺乏关于药物对老年人群影响的有力证据令人担忧。此外,许多与年龄相关的药代动力学变化和体内平衡能力的个体间变异性表明,将在年轻和健康参与者中进行的试验的证据转化为老年患者的常规管理时要谨慎。已经开发了一些决策工具,以防止老年人的不当处方和多种用药;然而,需要进一步的研究来证明其广泛的临床应用是合理的。传统的以疾病为中心的终点的作用基于客观的反应标志,可能还需要重新审视和补充自我评估健康的措施,特别是在可能身体虚弱或生活质量较差的老年患者中。本文概述了老年人的药物管理,特别是与处方、多种药物和不适当药物使用的趋势有关,以及决策工具的发展,这些工具可能促进老年人的个性化治疗计划。
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引用次数: 0
COVID-19 disease: a critical care perspective COVID-19疾病:重症监护视角
Pub Date : 2020-07-01 DOI: 10.1016/j.intcar.2020.100003
Chris Carter, Joy Notter

COVID-19 is a new highly infectious disease with an incompletely described clinical course, which has caused a pandemic, with Europe being identified as the third epicentre. COVID-19 has placed unprecedented pressure on critical care services which is likely to stretch resources beyond capacity. The situation is exacerbated by increased staff absence from self-isolation and illness, increased referral of patients with suspected or confirmed COVID-19 who develop respiratory failure, and limited availability of Extra Corporeal Membrane Oxygenation (ECMO) services. In addition, there is the ongoing challenge of patients being transferred between departments and hospitals for ongoing care. In consequence, as current needs continue to rise, innovative approaches are needed to redress shortages and support the continuance of services. This article provides an overview of severe COVID-19 infection, outlining treatment strategies and nursing processes that will need to develop and extend in response to this evolving situation.

COVID-19是一种新的高传染性疾病,临床过程描述不完整,已引起大流行,欧洲被确定为第三个震中。COVID-19给重症监护服务带来了前所未有的压力,这可能会使资源超出能力范围。由于越来越多的工作人员不进行自我隔离和生病,出现呼吸衰竭的疑似或确诊COVID-19患者转诊增加,以及体外膜氧合(ECMO)服务的可用性有限,情况进一步恶化。此外,病人在不同部门和医院之间转诊以接受持续治疗也是一个挑战。因此,由于目前的需求继续增加,需要采取创新的办法来弥补短缺和支持服务的继续。本文概述了COVID-19严重感染情况,概述了为应对这一不断变化的形势,需要制定和推广的治疗策略和护理流程。
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引用次数: 16
COVID-19 disease: invasive ventilation COVID-19疾病:有创通气
Pub Date : 2020-07-01 DOI: 10.1016/j.intcar.2020.100004
Chris Carter, Michelle Osborn, Gifty Agagah, Helen Aedy, Joy Notter

This article focuses on the critical care nurse's role in the management of patients with COVID-19 who require invasive ventilation in order to improve outcomes and prevent complications. The nature of COVID-19 is such that many patients deteriorate rapidly and for members of this group requiring intubation and invasive ventilation, different approaches to airway management and ventilatory support are required. In order to reduce the risk of complications and an overview of invasive ventilation, including commonly used modes, potential complications, nursing care, weaning and extubation are all described. COVID-19 presents several challenges as the disease progresses, hypoxemia may worsen, and the patient can develop Acute Respiratory Distress Syndrome. Therefore, additional treatment strategies including the use of the prone position and the use of nitric oxide and prostacyclin nebulisers have been included. The strategies presented in this article are relevant to both critical care nurses and those re-deployed to intensive care units where nurses will inevitably be involved in the management of patients requiring invasive ventilation. Weaning these patients off invasive ventilation is multi-factorial and may be short or long term. A multi-disciplinary weaning plan, the principles, stages/phases, and speed of weaning with expected parameters prior extubation are explained. Planned and unplanned extubation with the serious complications of the latter as the patient may not be ready and may require emergency re-intubation resulting in setbacks should be avoided.

本文重点介绍重症监护护士在COVID-19患者管理中的作用,这些患者需要有创通气,以改善预后并预防并发症。COVID-19的性质使许多患者病情迅速恶化,对于需要插管和有创通气的这一群体的成员,需要采取不同的气道管理和通气支持方法。为了降低并发症的发生风险,对有创通气进行概述,包括常用的通气方式、潜在的并发症、护理、脱机和拔管。随着疾病的进展,COVID-19带来了一些挑战,低氧血症可能会恶化,患者可能会出现急性呼吸窘迫综合征。因此,额外的治疗策略包括使用俯卧位和使用一氧化氮和前列环素喷雾器。本文中提出的策略既适用于重症监护护士,也适用于那些重新部署到重症监护病房的护士,在重症监护病房,护士将不可避免地参与需要有创通气的患者的管理。使这些患者脱离有创通气是多因素的,可能是短期的,也可能是长期的。多学科脱机计划,原则,阶段/阶段,脱机速度与拔管前预期参数的解释。应避免计划内拔管和计划外拔管,后者的严重并发症,因为患者可能没有准备好,可能需要紧急重新插管,导致挫折。
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引用次数: 22
COVID-19 disease: Non-Invasive Ventilation and high frequency nasal oxygenation COVID-19疾病:无创通气和高频鼻氧合
Pub Date : 2020-07-01 DOI: 10.1016/j.intcar.2020.100006
Chris Carter, Helen Aedy, Joy Notter

Severe COVID-19 causes significant numbers of patients to develop respiratory symptoms that require increasing interventions. Initially, the treatment for severe respiratory failure included early intubation and invasive ventilation, as this was deemed preferable to be more effective than Non-Invasive Ventilation (NIV). However, emerging evidence has shown that NIV may have a more significant and positive role than initially thought. NIV includes Continuous Positive Airway Pressure (CPAP) and Bi-Level Positive Airway Pressure (BiPAP). CPAP is the method of choice with the use of BiPAP for those with complex respiratory conditions who contract COVID-19. The use of High Flow Nasal Oxygen (HFNO) remains contentious with different perspectives in how this modality can be used to treat respiratory failure in COVID-19.

Current thinking suggests that NIV and HFNO may be an appropriate bridging adjunct in the early part of the disease progress and may prevent the need for intubation or invasive ventilation. Patients requiring NIV or HFNO may be nursed in locations outside of the critical care unit. Therefore, this article reviews the different types of NIV and HFNO, indications and the nursing care.

严重的COVID-19导致大量患者出现呼吸道症状,需要更多的干预措施。最初,严重呼吸衰竭的治疗包括早期插管和有创通气,因为这被认为比无创通气(NIV)更有效。然而,新出现的证据表明,NIV可能比最初认为的更重要和积极的作用。NIV包括持续气道正压(CPAP)和双水平气道正压(BiPAP)。对于感染COVID-19的复杂呼吸系统疾病患者,CPAP是使用BiPAP的首选方法。高流量鼻氧(HFNO)的使用仍然存在争议,对于如何使用这种方式治疗COVID-19呼吸衰竭存在不同的观点。目前的想法表明,在疾病进展的早期阶段,NIV和HFNO可能是一种适当的桥接辅助手段,并可能防止插管或有创通气的需要。需要NIV或HFNO的患者可以在重症监护病房以外的地方护理。因此,本文就NIV和HFNO的不同类型、适应证及护理进行综述。
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引用次数: 41
COVID-19 disease: assessment of a critically ill patient COVID-19疾病:一名危重病人的评估
Pub Date : 2020-07-01 DOI: 10.1016/j.intcar.2020.100001
Chris Carter, Helen Aedy, Joy Notter

With the major scale up of critical care services to respond to the increasing numbers of patients with severe COVID-19 infection, nurses need to be able to rapidly assess patients. While many patients present with signs of viral pneumonia and may develop respiratory failure, it is essential that the subsequent systemic complications are also recognized. Due to the unprecedented numbers of patients requiring critical care, many of them will initially have to be managed in emergency departments and acute wards until a critical care bed becomes available. In this article, the assessment of a patient with suspected or confirmed severe COVID-19 has been presented initially from a ward perspective, followed by that of critical care, using the Airway, Breathing, Circulation, Disability and Exposure (ABCDE) approach. This article has been specifically designed to enable nurses to systematically assess patients and prioritise care.

随着重症监护服务的大规模扩大,以应对越来越多的COVID-19严重感染患者,护士需要能够快速评估患者。虽然许多患者表现出病毒性肺炎的体征,并可能发展为呼吸衰竭,但也必须认识到随后的全身并发症。由于需要重症监护的患者数量空前,他们中的许多人最初将不得不在急诊科和急性病房进行管理,直到有重症监护床位可用。本文首先从病房角度对疑似或确诊的重症COVID-19患者进行评估,然后采用气道、呼吸、循环、残疾和暴露(ABCDE)方法对重症监护进行评估。这篇文章是专门设计的,使护士能够系统地评估病人和优先护理。
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引用次数: 3
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Clinics in Integrated Care
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