Pub Date : 2002-01-01DOI: 10.1080/1475956021000020206
R. Talar-Wojnarowska, A. Sasor, J. Strzelczyk, E. Małecka-Panas
{"title":"Molecular Basis of Pancreatic Cancer--Selected Issues","authors":"R. Talar-Wojnarowska, A. Sasor, J. Strzelczyk, E. Małecka-Panas","doi":"10.1080/1475956021000020206","DOIUrl":"https://doi.org/10.1080/1475956021000020206","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"8 1","pages":"147-152"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84354508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/1475956021000015086
J. Sayfan
{"title":"Surgery for Inflammatory Bowel Diseases and Prevention of Gastrointestinal Malignancies","authors":"J. Sayfan","doi":"10.1080/1475956021000015086","DOIUrl":"https://doi.org/10.1080/1475956021000015086","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"88 1","pages":"143-145"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84149919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/1475956021000015103
Mohamed M. Eida, Abd Elraouf El Deib, A. Saad, I. Perry, David Roland, M. Dixon, J. Jankowski
{"title":"Down-regulation of E-cadherin and β-catenin in Helicobacter pylori Associated Gastritis and Gastric Carcinoma: An Immunohistochemical Study","authors":"Mohamed M. Eida, Abd Elraouf El Deib, A. Saad, I. Perry, David Roland, M. Dixon, J. Jankowski","doi":"10.1080/1475956021000015103","DOIUrl":"https://doi.org/10.1080/1475956021000015103","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"111 1","pages":"203-208"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79919843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/1475956021000020215
I. Rácz, A. Szabó, M. Goda, A. Oláh
{"title":"Preliminary Colorectal Cancer Screening Program Model in Hungary","authors":"I. Rácz, A. Szabó, M. Goda, A. Oláh","doi":"10.1080/1475956021000020215","DOIUrl":"https://doi.org/10.1080/1475956021000020215","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"19 1","pages":"119-121"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89588709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/14759560290029614
Yoon Kim, Hanhui Yang, S. Oh
Purpose: Bombesin-like peptides are known to be important in the autocrine growth of a number of smlll cell lung cancer cell lines. The aim of this study was to investigate the extent of bombesin family ligands/receptors expression in human gastric cancer tissues and cell lines, and to evaluate the relationship between the expression of bombesin family Iigands/receptor and clinicopathologic parameters. Methods: We measured the expression of gstrin releasing peptide (GAP), neuromedin B (NMB), and their receptors, in human gastric cancer tissues and cell lines. Ligand and receptor mRNA studies were carried out on: 20 tumor and matched normal samples, and 9 gastric cell lines. The expression of mRNA of GRP/NMB, and their receptors, was examined by the reverse transcription-polymerase chain reaction (RT-PCR). Results: Expression of GRP, NMB and GRPR, NMBR mRNA was found in 55%, 100%, 40%, and 100% of gastric cancer tissue, respectively. GRP/GRPR co-expression was observed in 30% of gastric cancer tissues and expression of gastric cancer was higher than that of normal mucosa. GRP and GRPR were highly expressed in the differentiated type of gastric cancer. In gastric cancer cell lines, these peptides and receptors were expressed equally. Conclusion: The result demonstrate that GRP, NMB, GRPR, and NMBR were expressed in gastric cancer tissues and cell lines. This result suggests that these may have a role as growth factors in gastric cancer growth, and these peptides may act in an autocrine fashion as a morphogen in gastric cancer.
{"title":"Expression of Bombesin Family Ligands and Receptors in Human Gastric Cancer Tissues and Cell Lines.","authors":"Yoon Kim, Hanhui Yang, S. Oh","doi":"10.1080/14759560290029614","DOIUrl":"https://doi.org/10.1080/14759560290029614","url":null,"abstract":"Purpose: Bombesin-like peptides are known to be important in the autocrine growth of a number of smlll cell lung cancer cell lines. The aim of this study was to investigate the extent of bombesin family ligands/receptors expression in human gastric cancer tissues and cell lines, and to evaluate the relationship between the expression of bombesin family Iigands/receptor and clinicopathologic parameters. Methods: We measured the expression of gstrin releasing peptide (GAP), neuromedin B (NMB), and their receptors, in human gastric cancer tissues and cell lines. Ligand and receptor mRNA studies were carried out on: 20 tumor and matched normal samples, and 9 gastric cell lines. The expression of mRNA of GRP/NMB, and their receptors, was examined by the reverse transcription-polymerase chain reaction (RT-PCR). Results: Expression of GRP, NMB and GRPR, NMBR mRNA was found in 55%, 100%, 40%, and 100% of gastric cancer tissue, respectively. GRP/GRPR co-expression was observed in 30% of gastric cancer tissues and expression of gastric cancer was higher than that of normal mucosa. GRP and GRPR were highly expressed in the differentiated type of gastric cancer. In gastric cancer cell lines, these peptides and receptors were expressed equally. Conclusion: The result demonstrate that GRP, NMB, GRPR, and NMBR were expressed in gastric cancer tissues and cell lines. This result suggests that these may have a role as growth factors in gastric cancer growth, and these peptides may act in an autocrine fashion as a morphogen in gastric cancer.","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"100 1","pages":"198-204"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76989426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/14759560290019804
John W. C. Chen, D. Mirza
{"title":"Radiofrequency Ablation of Liver Tumours","authors":"John W. C. Chen, D. Mirza","doi":"10.1080/14759560290019804","DOIUrl":"https://doi.org/10.1080/14759560290019804","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"10 1","pages":"15-16"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81994077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/1475956021000018614
K. Yassin, E. Vlodavsky, R. Eliakim
{"title":"Recurrent Upper Gastrointestinal Bleeding Caused by a Giant Brunneroma--Report of a Case Treated Endoscopically","authors":"K. Yassin, E. Vlodavsky, R. Eliakim","doi":"10.1080/1475956021000018614","DOIUrl":"https://doi.org/10.1080/1475956021000018614","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"26 1","pages":"173-179"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89392492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/1475956021000017057
S. Böhm
{"title":"Hyperplastic Polyps of the Colorectum--Do They Possess a Malignant Potential?","authors":"S. Böhm","doi":"10.1080/1475956021000017057","DOIUrl":"https://doi.org/10.1080/1475956021000017057","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"67 1","pages":"97-117"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78814487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/14759560290032746
J. King, J. Caplehorn, J. Seifert, A. Preketes, P. Clingan, D. Morris
{"title":"A Randomised Placebo Control Double-blind Trial of Ranitidine in Patients with Colorectal Hepatic Metastases: Survival Advantage in Patients with Poor Cell Mediated Immunity","authors":"J. King, J. Caplehorn, J. Seifert, A. Preketes, P. Clingan, D. Morris","doi":"10.1080/14759560290032746","DOIUrl":"https://doi.org/10.1080/14759560290032746","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"91 6 1","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77983759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2002-01-01DOI: 10.1080/14759560290032755
J. Kaczynski, E. Holmberg, A. Odén, S. Wallerstedt
{"title":"Remarkable Association Between Liver and Kidney Cancer","authors":"J. Kaczynski, E. Holmberg, A. Odén, S. Wallerstedt","doi":"10.1080/14759560290032755","DOIUrl":"https://doi.org/10.1080/14759560290032755","url":null,"abstract":"","PeriodicalId":100490,"journal":{"name":"ESMO Gastrointestinal Oncology","volume":"57 1","pages":"45-47"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91003161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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