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Boehringer Ingelheim: advances in oncology and diabetes 勃林格殷格翰:在肿瘤和糖尿病领域取得进展
Pub Date : 2011-01-20 DOI: 10.1002/fps.72

This series of company profiles looks at some of the major players in the UK pharmaceutical industry, their current areas of expertise, and forthcoming products and initiatives that will have an impact on therapeutics and prescribing in the near future. In this article we provide an overview of Boehringer Ingelheim and its current portfolio, and look at its pipeline of new drugs and areas of research interest.

本系列公司简介着眼于英国制药行业的一些主要参与者,他们目前的专业领域,以及即将推出的产品和计划,这些产品和计划将在不久的将来对治疗和处方产生影响。在本文中,我们将概述勃林格殷格翰公司及其目前的投资组合,并着眼于其新药管道和研究兴趣领域。
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引用次数: 0
The promise of future treatments in AF: is it all over for warfarin? 心房颤动的未来治疗前景:华法林是否已经结束?
Pub Date : 2010-07-13 DOI: 10.1002/fps.64
Sotiris Antoniou BPharm (Hons), MSc, DipMgt

Aspirin and warfarin are currently the only treatment options for patients presenting with atrial fibrillation at risk of stroke. New oral direct thrombin inhibitors may offer an additional choice or viable alternative. Here we consider their potential role with a focus on dabigatran. Copyright © 2010 John Wiley & Sons, Ltd.

阿司匹林和华法林是目前心房颤动患者中风风险的唯一治疗选择。新的口服直接凝血酶抑制剂可能提供额外的选择或可行的替代方案。在这里,我们考虑它们的潜在作用,重点是达比加群。版权所有©2010 John Wiley &儿子,有限公司
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引用次数: 0
Novartis: new developments in multiple sclerosis and oncology 诺华:多发性硬化症和肿瘤学的新进展
Pub Date : 2010-07-13 DOI: 10.1002/fps.67

This series of company profiles looks at some of the major players in the UK pharmaceutical industry, their current areas of expertise, and forthcoming products and initiatives that will have an impact on therapeutics and prescribing in the near future. In this article we provide an overview of Novartis and its current portfolio, and look at its pipeline of new drugs and areas of research interest. Copyright © 2010 John Wiley & Sons, Ltd.

本系列公司简介着眼于英国制药行业的一些主要参与者,他们目前的专业领域,以及即将推出的产品和计划,这些产品和计划将在不久的将来对治疗和处方产生影响。在本文中,我们将概述诺华及其目前的投资组合,并研究其新药管道和研究兴趣领域。版权所有©2010 John Wiley &儿子,有限公司
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引用次数: 0
Cost of shingles to patients and the NHS: hope on the horizon? 带状疱疹对患者和NHS的成本:希望在地平线上?
Pub Date : 2010-07-13 DOI: 10.1002/fps.66
Joanna Lumb

Shingles carries a considerable burden to patients and to the health service. The expected introduction of routine shingles vaccination raises hope for reducing this debilitating infection and its complications. Copyright © 2010 John Wiley & Sons, Ltd.

带状疱疹给病人和卫生服务带来了相当大的负担。预期引入的常规带状疱疹疫苗接种为减少这种使人衰弱的感染及其并发症带来了希望。版权所有©2010 John Wiley &儿子,有限公司
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引用次数: 2
New directions in cancer therapy - HDAC inhibitors 癌症治疗的新方向——HDAC抑制剂
Pub Date : 2010-03-15 DOI: 10.1002/fps.60
Stephen Schey FRCP, FRACP, FRCPath

The HDACis (histone deacetylation inhibitors) are an active class of drugs that have been used to treat a wide variety of tumours including breast cancer, prostate cancer, multiple myeloma, thyroid cancer and Hodgkin's and non-Hodgkin's lymphoma. One HDAC, vorinostat, has been licensed by the FDA, but more work is needed to identify and delineate the histone and nonhistone targets of these agents. In this article, Dr Steve Schey considers the place of HDACis in future cancer therapy. Copyright © 2010 John Wiley & Sons, Ltd.

HDACis(组蛋白去乙酰化抑制剂)是一类活性药物,已被用于治疗多种肿瘤,包括乳腺癌、前列腺癌、多发性骨髓瘤、甲状腺癌、霍奇金淋巴瘤和非霍奇金淋巴瘤。一种HDAC,伏立诺他,已经获得了FDA的许可,但需要更多的工作来确定和描述这些药物的组蛋白和非组蛋白靶点。在这篇文章中,Steve Schey博士考虑了HDACis在未来癌症治疗中的地位。版权所有©2010 John Wiley &儿子,有限公司
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引用次数: 0
COPD management: new and existing therapy options 慢性阻塞性肺病管理:新的和现有的治疗方案
Pub Date : 2010-03-15 DOI: 10.1002/fps.62
David Price MA, MRCGP, DRCOG, Rhonda Siddall

Early detection and appropriate management of chronic obstructive pulmonary disease (COPD) may help to reduce the high mortality and morbidity associated with this disease. New pharmacological treatments for COPD, along with the implementation of recommendations of the National Strategy for COPD due for publication later this year, will help to raise the standard of care and improve outcomes for COPD patients. In this article, Professor Price and Rhonda Siddall consider current COPD therapy and look at future treatment options for COPD. Copyright © 2010 John Wiley & Sons, Ltd.

慢性阻塞性肺疾病(COPD)的早期发现和适当管理可能有助于降低与该疾病相关的高死亡率和发病率。新的COPD药物治疗方法,以及将于今年晚些时候公布的COPD国家战略建议的实施,将有助于提高COPD患者的护理标准和改善预后。在这篇文章中,Price教授和Rhonda Siddall考虑了目前COPD的治疗方法,并展望了未来COPD的治疗选择。版权所有©2010 John Wiley &儿子,有限公司
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引用次数: 0
Grünenthal: developing and expanding in pain research grental:疼痛研究的发展和扩展
Pub Date : 2010-03-15 DOI: 10.1002/fps.61

This series of company profiles looks at some of the major players in the UK pharmaceutical industry, their current areas of expertise, and forthcoming products and initiatives that will have an impact on therapeutics and prescribing in the near future. In this article we provide an overview of Grünenthal and its current portfolio, and look at the current pipeline and areas of research interest. Copyright © 2010 John Wiley & Sons, Ltd.

本系列公司简介着眼于英国制药行业的一些主要参与者,他们目前的专业领域,以及即将推出的产品和计划,这些产品和计划将在不久的将来对治疗和处方产生影响。在本文中,我们概述了gr nenthal及其当前的投资组合,并查看了当前的管道和研究兴趣领域。版权所有©2010 John Wiley &儿子,有限公司
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引用次数: 0
Comparing notes: cancer leaders discuss the latest advances 交换意见:癌症领袖讨论最新进展
Pub Date : 2009-12-24 DOI: 10.1002/fps.58

New data from different tumour types highlight similarities and differences for specialists, as presented at the Cancer Congress Update meeting held in London, July 2009

2009年7月在伦敦举行的癌症大会更新会议上,来自不同肿瘤类型的新数据为专家们强调了相似性和差异性
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引用次数: 0
New developments in multiple sclerosis and pain management 多发性硬化症和疼痛管理的新进展
Pub Date : 2009-12-24 DOI: 10.1002/fps.59
Kerry Laundon

Promising studies were reported at the 25th congress of the European Committee for Treatment and Research in MS (ECTRIMS), held on 9-12 September 2009 in Düsseldorf, Germany, while data on a new treatment for chronic low back pain was presented at the 6th Triennial congress of the European Federation of Chapters (EFIC) of the International Association for the Study of Pain (IASP), held on 9-12 September 2009 in Lisbon, Portugal. Copyright © 2009 John Wiley & Sons, Ltd.

2009年9月9日至12日在德国杜塞尔多夫举行的欧洲多发性硬髓炎治疗和研究委员会(ECTRIMS)第25届大会上报告了有希望的研究,而2009年9月9日至12日在葡萄牙里斯本举行的国际疼痛研究协会(IASP)欧洲分会联合会(EFIC)第6届三年一次的大会上介绍了慢性腰痛新治疗方法的数据。版权所有©2009 John Wiley &儿子,有限公司
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引用次数: 0
Certolizumab pegol: a new option for rheumatoid arthritis Certolizumab pegol:类风湿关节炎的新选择
Pub Date : 2009-12-24 DOI: 10.1002/fps.57
Margaret HY Ma MBBS, BSc, MRCP, MSc, Ernest HS Choy MD FRCP

Rheumatoid arthritis (RA) presents a significant burden to healthcare in the UK. New biological therapies have advanced treatment but at a high cost to the NHS. Certolizumab pegol is a new TNF inhibitor, providing an additional treatment option for RA. In this article Dr Ma and Dr Choy consider the efficacy of certolizumab pegol, and where it may fit into the RA armoury. Copyright © 2009 John Wiley & Sons, Ltd.

类风湿性关节炎(RA)是英国医疗保健的一个重大负担。新的生物疗法有先进的治疗方法,但对NHS来说成本很高。Certolizumab pegol是一种新的TNF抑制剂,为RA提供了额外的治疗选择。在这篇文章中,Ma博士和Choy博士考虑了certolizumab pegol的疗效,以及它可能适合RA军械库的位置。版权所有©2009 John Wiley &儿子,有限公司
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引用次数: 0
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Future Prescriber
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