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The role of dapagliflozin in non-compaction cardiomyopathy for refractory heart failure with reduced ejection fraction: 4th pillar for unstable disorder 达格列净在难治性心力衰竭伴射血分数降低的非压实性心肌病中的作用:不稳定障碍的第四大支柱
Pub Date : 2022-10-01 DOI: 10.1016/j.ihjccr.2022.11.004
Pankaj V. Jariwala , Dilip Gude

Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, has been shown in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure (DAPA-HF) study to significantly decrease mortality or hospitalisation in patients with heart failure with reduced ejection fraction (HFrEF). We describe a case of a patient with noncompaction cardiomyopathy (NCCM) who initially responded partially to guideline-directed medical therapy, which included an angiotensin receptor-neprilysin inhibitor (ARNI). However, the patient's symptoms returned, and the addition of dapagliflozin was able to provide a definitive improvement in his clinical-echocardiographic parameters. There is currently no data indicating that dapagliflozin is beneficial for patients with NCCM and HFrEF which progressive disorder.

达格列净是一种钠-葡萄糖共转运蛋白-2抑制剂,在达格列净和预防心力衰竭不良结局(DAPA-HF)研究中显示,达格列净可显著降低射血分数降低(HFrEF)心力衰竭患者的死亡率或住院率。我们描述了一例患有非压实性心肌病(NCCM)的患者,他最初对指南指导的药物治疗有部分反应,其中包括血管紧张素受体-neprilysin抑制剂(ARNI)。然而,患者的症状又出现了,添加达格列净能够提供他的临床超声心动图参数的明确改善。目前没有数据表明达格列净对进行性疾病的NCCM和HFrEF患者有益。
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引用次数: 0
RV outpouching in a case of Right ventricular endomyocardial fibrosis with sick sinus syndrome 右心室心肌内膜纤维化伴病态窦性综合征1例
Pub Date : 2022-10-01 DOI: 10.1016/j.ihjccr.2022.11.001
Gousia Mukhtar , Viswanatha Kartik Sambaturu , Ajay Alex , Narayanan Namboodiri
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引用次数: 0
Claws and effect: A case of Pantoea Agglomerans endocarditis following a cat scratch and literature review 爪子与效果:猫抓伤致泛癣凝聚性心内膜炎1例并文献复习
Pub Date : 2022-10-01 DOI: 10.1016/j.ihjccr.2022.11.003
Kyle Admire, Charlotta Jornlid, R. Allen Blackwood

Pantoea Agglomerans is an environmental gram-negative aerobic bacillus in the Enterobacteriaceae family. Typically, it is not responsible for infections in humans. We present the case of an immunocompetent patient who developed Pantoea Agglomerans bacteremia, Cardiovascular Implantable Electronic Device (CIED)-related endocarditis, and cholecystitis following a cat scratch. Following this case, we performed a review of the available literature regarding Pantoea Agglomerans. Overall, infections in humans are very well-treated with few strains of Pantoea Agglomerans demonstrating resistance to antimicrobial therapy.

Learning objective

Recognize uncommon bacterial etiologies of endocarditis and review treatment modalities for Pantoea infections.

Pantoea Agglomerans是肠杆菌科的一种环境革兰氏阴性需氧杆菌。通常情况下,它不会导致人类感染。我们提出了一个免疫功能正常的病人谁发展Pantoea团聚菌血症,心血管植入式电子设备(CIED)相关的心内膜炎,胆囊炎后猫抓。在这个病例之后,我们对现有的关于Pantoea Agglomerans的文献进行了回顾。总的来说,人类感染得到了很好的治疗,很少有Pantoea Agglomerans菌株显示出对抗菌药物治疗的耐药性。学习目的认识心内膜炎不常见的细菌病因,并回顾Pantoea感染的治疗方法。
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引用次数: 0
Early outcomes of surgical repair of post infarct ventricular septal rupture: A single centre experience 梗死后室间隔破裂手术修复的早期结果:单中心经验
Pub Date : 2022-10-01 DOI: 10.1016/j.ihjccr.2022.09.007
Ranajit Beeranna Naik, Chandra Prakash Srivastava, Ankit Mathur, Sunil Sharma, Omeshwar Sharma

Aim and objective

Ventricular Septal Rupture (VSR) is a fatal mechanical complication of myocardial infarction. The aim of this study is to evaluate the early outcomes of the surgical repair and also to identify the risk factors related to early mortality at our centre.

Materials and methods

It is a retrospective study that includes the assessment of clinical data of 8 adult patients with post infarct VSR who underwent surgical repair at our centre. The study duration was between January 2017 and December 2021. All the patients included in the study underwent surgical repair of Post infarct VSR.

Results

The median age of the patients was 68 years (Range 52–77 years). The most common location of VSR was predominantly in the anterior and apical septum (62.5%). The overall early mortality in our study was 50% (n = 4). The risk factors and preoperative complications were similar among the survivors and non survivors.

Conclusion

Post infarct ventricular septal repair has high early operative mortality. It is difficult to predict the risk factors contributing to the high rate of early mortality in these patients.

目的与目的室间隔破裂(ventricular Septal Rupture, VSR)是心肌梗死的致死性机械并发症。本研究的目的是评估手术修复的早期结果,并确定与本中心早期死亡相关的危险因素。材料和方法本研究是一项回顾性研究,包括对在本中心接受手术修复的8例梗死后VSR成年患者的临床资料进行评估。研究时间为2017年1月至2021年12月。所有纳入研究的患者都接受了梗死后VSR的手术修复。结果患者年龄中位数为68岁(52 ~ 77岁)。VSR最常见的位置主要在前鼻中隔和鼻尖(62.5%)。在我们的研究中,总体早期死亡率为50% (n = 4)。幸存者和非幸存者的危险因素和术前并发症相似。结论梗死后室间隔修复术后早期手术死亡率高。很难预测导致这些患者高早期死亡率的危险因素。
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引用次数: 0
Complete atrioventricular block complicated by QT prolongation triggering repeated torsades de pointes polymorphic ventricular tachycardia 完全性房室传导阻滞合并QT间期延长,引发反复点扭转和多形性室性心动过速
Pub Date : 2022-10-01 DOI: 10.1016/j.ihjccr.2022.11.005
Deepak Natarajan

This case report describes a 30 years old female who presented to the Emergency with multiple blackouts the previous 3 days. In the Emergency a Torsades de pointes (TdP) polymorphic ventricular tachycardia was observed on the cardiac monitor that spontaneously resolved into complete atrioventricular block accompanied by significantly prolonged QT and corrected QT (QTc)intervals. The patient underwent immediate temporary pacing, followed by permanent dual chamber implantation the next day. There were no further episodes of TdP subsequent to pacemaker implantation; the patient was discharged on a beta-blocker. Complete atrioventricular block when accompanied by increased QTc interval can result in lethal ventricular tachyarrhythmia manifesting as pre syncope, syncope, cardiac arrest, or death. Such patients, albeit uncommon, may be managed by permanent pacing and beta blocker therapy.

本病例报告描述了一名30岁女性,她在前3天多次昏厥。在急诊a点扭转(TdP)时,在心脏监护仪上观察到多形性室性心动过速,自发分解为完全房室传导阻滞,并伴有QT间期明显延长和QT间期纠正。患者接受了即时临时起搏,第二天进行了永久性双腔植入。起搏器植入后无TdP进一步发作;病人在服用受体阻滞剂后出院。完全性房室传导阻滞伴QTc间期增加可导致致死性室性心动过速,表现为晕厥前期、晕厥、心脏骤停或死亡。这类患者虽然不常见,但可以通过永久性起搏和受体阻滞剂治疗来管理。
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引用次数: 0
A case series illustrating the utility of ‘over the wire’ technique and its modifications during percutaneous transvenous mitral commissurotomy 一个案例系列说明了在经皮经静脉二尖瓣合并术中“线上”技术的应用及其改进
Pub Date : 2022-10-01 DOI: 10.1016/j.ihjccr.2022.09.009
Satish Karur, Ravindranath K S, Ravi S. Math, Laxmi H. Shetty, Natesh B H, Sunil Kumar K R, C.N. Manjunath

The efficacy and safety of percutaneous transvenous mitral commissurotomy by the Inoue technique, in patients with rheumatic mitral stenosis is well known. However, presence of left atrial/appendage thrombus or difficult LV entry entails the use of ‘over the wire’(OTW)technique. Here we describe a case series highlighting the utility and modifications of OTW technique.

经皮经静脉二尖瓣切开术治疗风湿性二尖瓣狭窄的有效性和安全性是众所周知的。然而,存在左心房/附件血栓或左室进入困难需要使用“线外”(OTW)技术。在这里,我们描述了一个案例系列,突出了OTW技术的实用性和修改。
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引用次数: 0
HyperCKemia and Sheehan's syndrome mimicking acute coronary syndrome 高血凝症和希恩氏综合征模拟急性冠状动脉综合征
Pub Date : 2022-10-01 DOI: 10.1016/j.ihjccr.2022.11.002
K. Subramanyam , Dilip Johny , Shri Krishna Acharya , Sudhindra Mananje , Yogesh Kini K

A 56-year-old lady presented with chest discomfort for 2 days. Electrocardiography showed deep T wave inversions in the anterior leads. Cardiac Troponin was elevated. Her creatine phosphokinase (CPK) was disproportionately high compared to the elevation of creatine kinase myocardial band (CKMB). The patient had severe hyponatremia which was due to decreased cortisol levels. Her coronary angiogram was normal. She was a known hypothyroid, other hormonal analyses showed low levels of cortisol, Adreno Corticotropic Hormone (ACTH), Follicle Stimulating Hormone (FSH), and Luteinizing Hormone (LH), hence diagnosis of panhypopituitarism, Sheehan's syndrome was made. The patient was stabilized and discharged on oral steroids.

56岁女性,胸部不适2天。心电图显示前导联深T波反转。心肌肌钙蛋白升高。她的肌酸磷酸激酶(CPK)与肌酸激酶心肌带(CKMB)的升高不成比例地高。患者有严重的低钠血症,这是由于皮质醇水平降低所致。她的冠状动脉造影正常。她患有甲状腺功能减退症,其他激素分析显示皮质醇、促肾上腺皮质激素(ACTH)、促卵泡激素(FSH)和促黄体生成素(LH)水平低,因此诊断为全垂体功能减退症,希恩综合征。患者病情稳定,经口服类固醇治疗出院。
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引用次数: 0
An unusual cause of tachycardia induced cardiomyopathy in an adult 一个不寻常的原因心动过速诱发心肌病在一个成年人
Pub Date : 2022-10-01 DOI: 10.1016/j.ihjccr.2022.09.006
Akinchan Bhardwaj, Ashish Jain, Raja J. Selvaraj

Permanent junctional reciprocating tachycardia (PJRT) is a form of atrioventricular reentrant tachycardia which is common in infants and children and presents rarely in adults. It is an incessant form of tachycardia which can lead to tachycardia induced cardiomyopathy. It tends to be unresponsive to most drug treatment but potentially treatable by radiofrequency ablation. Here we report a case of PJRT in an adult patient presenting as tachycardia induced cardiomyopathy.

永久性交界性往复式心动过速(PJRT)是房室折返性心动过速的一种形式,常见于婴儿和儿童,在成人中很少出现。它是一种持续形式的心动过速,可导致心动过速诱发心肌病。它往往对大多数药物治疗无反应,但有可能通过射频消融术治疗。在这里,我们报告一例PJRT在一个成人患者表现为心动过速引起的心肌病。
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引用次数: 1
Two cases of left main coronary artery compression by dilated pulmonary artery 肺动脉扩张压迫左冠状动脉主干2例
Pub Date : 2022-07-01 DOI: 10.1016/j.ihjccr.2022.09.005
Sourabh Goswami, Surender Deora, Atul Kaushik

Left main coronary artery compression is an underrecognized condition in patients with pulmonary artery hypertension. If present, it may lead to dismal outcome. In young patients with pulmonary hypertension or in patients with hugely dilated pulmonary artery with symptoms of angina, left main coronary compression must be ruled out.

肺动脉高压患者的左主干冠状动脉受压是一种未被充分认识的疾病。如果出现这种情况,可能会导致令人沮丧的结果。年轻肺动脉高压患者或有心绞痛症状的肺动脉巨大扩张患者,必须排除左主干冠状动脉压迫。
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引用次数: 0
A cathlab nightmare – Piggybacking of stents!! 血化科的噩梦——支架背负!!
Pub Date : 2022-07-01 DOI: 10.1016/j.ihjccr.2022.08.001
Shishir Kumar Roul, Muni Venkatesa Reddy, Saurabh Ajit Deshpande

Dislodgement of a fully deployed stent is an uncommon but dangerous complication associated with coronary interventions. A new stent may get stuck that may inadvertently remove the previous stent in a piggybacking fashion. We hereby present a case of piggybacking of stents which was managed without any further complications.

完全展开支架的移位是冠状动脉介入手术中一种罕见但危险的并发症。一个新的支架可能会被卡住,这可能会在不经意间以承载的方式移除之前的支架。我们在此提出一例支架的背载,没有任何进一步的并发症。
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引用次数: 0
期刊
IHJ Cardiovascular Case Reports (CVCR)
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