首页 > 最新文献

Journal of Indian College of Cardiology最新文献

英文 中文
Prevalence of Metabolic Syndrome and its Clinical and Angiographic Profile in Patients with Naive Acute Coronary Syndrome 原发性急性冠脉综合征患者代谢综合征的患病率及其临床和血管造影特征
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_41_22
Mahmood Dhahir Al-Mendalawi
Sir, Kumar et al.[1] found in their study that the metabolic syndrome (MetS) prevalence was high (46.2%) among Indian patients with naive acute coronary syndrome (ACS) and patients with MetS tended to have more complex coronary lesions. Based on the following limitation, we believe that the study findings are questionable. The revised National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP III) guidelines[2] employed in the study to diagnose MetS include the following parameters: (1) abdominal obesity manifests as waist circumference (WC) ≥102 cm for men or ≥88 cm for women; (2) serum triglyceride (TG) level ≥150 mg/dL; (3) serum high-density lipoprotein cholesterol (HDLC) level ≤40 mg/dL for men or ≤50 mg/dL for women; (4) systolic/diastolic blood pressure (BP) ≥130/85 mmHg or receiving drug therapy; and (5) fasting plasma glucose (FBG) ≥100 mg/d. These guidelines were launched in 2005[2] and they are no more righteous. Around the world, many committees have built their MetS definition guidelines centered on various factors such as age, gender, pubertal stage, socioeconomic class, and ethnicity to accurately measure MetS prevalence.[3,4] Importantly, India released national diagnostic guidelines for MetS in 2016. These guidelines involve the following components: (1) WC ≥31” In women and ≥35” in men; (2) serum TG level ≥150 mg/dl; (3) serum HDLC level <50 mg/dl for women and <40 mg/dl for men; (4) BP ≥130/85 mmHg; and (5) FBG >100 mg/dl.[5] Since there are noticeable variations between the revised NCEP/ATP III guidelines[2] and national MetS diagnostic guidelines,[5] we believe that referring to the national guidelines could make an accurate estimate of the MetS prevalence among ACS Indian patients and assess the seriousness of coronary artery disease in those with and without MetS. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.
Sir、Kumar等[1]研究发现,印度初发急性冠脉综合征(ACS)患者中代谢综合征(MetS)患病率较高(46.2%),且met患者往往有更复杂的冠状动脉病变。基于以下限制,我们认为研究结果值得怀疑。本研究采用修订后的国家胆固醇教育计划/成人治疗小组III (NCEP/ATP III)指南[2]诊断MetS包括以下参数:(1)腹部肥胖表现为男性腰围(WC)≥102 cm或女性≥88 cm;(2)血清甘油三酯(TG)水平≥150mg /dL;(3)血清高密度脂蛋白胆固醇(HDLC)水平男性≤40 mg/dL,女性≤50 mg/dL;(4)收缩压/舒张压(BP)≥130/85 mmHg或正在接受药物治疗;(5)空腹血糖(FBG)≥100mg /d。这些指导方针于2005年推出[2],它们不再是正义的。在世界范围内,许多委员会已经建立了他们的MetS定义指南,以各种因素为中心,如年龄,性别,青春期阶段,社会经济阶层和种族,以准确衡量MetS的患病率。[3,4]重要的是,印度于2016年发布了met的国家诊断指南。这些指南包括以下内容:(1)女性WC≥31,男性WC≥35;(2)血清TG水平≥150mg /dl;(3)血清HDLC水平100 mg/dl。[5]由于修订后的NCEP/ATP III指南[2]与国家MetS诊断指南之间存在明显差异,[5]我们认为,参考国家指南可以准确估计ACS印度患者的MetS患病率,并评估有无MetS患者冠状动脉疾病的严重程度。财政支持及赞助无。利益冲突没有利益冲突。
{"title":"Prevalence of Metabolic Syndrome and its Clinical and Angiographic Profile in Patients with Naive Acute Coronary Syndrome","authors":"Mahmood Dhahir Al-Mendalawi","doi":"10.4103/jicc.jicc_41_22","DOIUrl":"https://doi.org/10.4103/jicc.jicc_41_22","url":null,"abstract":"Sir, Kumar et al.[1] found in their study that the metabolic syndrome (MetS) prevalence was high (46.2%) among Indian patients with naive acute coronary syndrome (ACS) and patients with MetS tended to have more complex coronary lesions. Based on the following limitation, we believe that the study findings are questionable. The revised National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP III) guidelines[2] employed in the study to diagnose MetS include the following parameters: (1) abdominal obesity manifests as waist circumference (WC) ≥102 cm for men or ≥88 cm for women; (2) serum triglyceride (TG) level ≥150 mg/dL; (3) serum high-density lipoprotein cholesterol (HDLC) level ≤40 mg/dL for men or ≤50 mg/dL for women; (4) systolic/diastolic blood pressure (BP) ≥130/85 mmHg or receiving drug therapy; and (5) fasting plasma glucose (FBG) ≥100 mg/d. These guidelines were launched in 2005[2] and they are no more righteous. Around the world, many committees have built their MetS definition guidelines centered on various factors such as age, gender, pubertal stage, socioeconomic class, and ethnicity to accurately measure MetS prevalence.[3,4] Importantly, India released national diagnostic guidelines for MetS in 2016. These guidelines involve the following components: (1) WC ≥31” In women and ≥35” in men; (2) serum TG level ≥150 mg/dl; (3) serum HDLC level <50 mg/dl for women and <40 mg/dl for men; (4) BP ≥130/85 mmHg; and (5) FBG >100 mg/dl.[5] Since there are noticeable variations between the revised NCEP/ATP III guidelines[2] and national MetS diagnostic guidelines,[5] we believe that referring to the national guidelines could make an accurate estimate of the MetS prevalence among ACS Indian patients and assess the seriousness of coronary artery disease in those with and without MetS. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case Report of Acute Coronary Syndrome Secondary to Active Crohn’s Disease 活动性克罗恩病继发急性冠脉综合征1例报告
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_30_21
Shishir Kumar Roul, Muni V. Reddy, Sharan Malipatil, Saurabh Ajit Deshpande
Chronic inflammation is a common factor between atherosclerosis and inflammatory bowel disease (IBD). IBD (both ulcerative colitis and Crohn’s disease [CD]) has been linked with arterial atherosclerotic events such as myocardial infarction (MI) and stroke. We present the case of a young male presenting with MI which was diagnosed to be due to an underlying CD.
慢性炎症是动脉粥样硬化和炎症性肠病(IBD)之间的共同因素。IBD(溃疡性结肠炎和克罗恩病[CD])与动脉粥样硬化事件如心肌梗死(MI)和中风有关。我们提出的情况下,一个年轻的男性表现为心肌梗死被诊断为由于一个潜在的乳糜泻。
{"title":"A Case Report of Acute Coronary Syndrome Secondary to Active Crohn’s Disease","authors":"Shishir Kumar Roul, Muni V. Reddy, Sharan Malipatil, Saurabh Ajit Deshpande","doi":"10.4103/jicc.jicc_30_21","DOIUrl":"https://doi.org/10.4103/jicc.jicc_30_21","url":null,"abstract":"Chronic inflammation is a common factor between atherosclerosis and inflammatory bowel disease (IBD). IBD (both ulcerative colitis and Crohn’s disease [CD]) has been linked with arterial atherosclerotic events such as myocardial infarction (MI) and stroke. We present the case of a young male presenting with MI which was diagnosed to be due to an underlying CD.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"293 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronary Artery Aneurysms Following Stenting 支架植入术后冠状动脉动脉瘤
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_9_22
Immaneni Sathyamurthy, Kanthallu Narayanamoorthy Srinivasan, Sasikala Subramanian
Coronary artery aneurysms are rare complications following stenting and were reported with drug-eluting as well as bare metal stents. They can be asymptomatic or present as acute coronary syndromes and usually detected during coronary angiography. The mechanisms responsible can be vascular trauma, hypersensitivity to drug, polymer, or metal. Rarely, it can be due to acute bacterial infections resulting in mycotic aneurysms. Management depends on symptoms, presentation, and underlying pathology and has to be tailored on a case-to-case basis.
冠状动脉动脉瘤是支架置入后罕见的并发症,药物洗脱和裸金属支架均有报道。它们可以无症状或表现为急性冠状动脉综合征,通常在冠状动脉造影时发现。其机制可能是血管损伤、对药物、聚合物或金属的过敏。很少,它可以是由于急性细菌感染导致真菌性动脉瘤。治疗取决于症状、表现和潜在病理,必须根据具体情况量身定制。
{"title":"Coronary Artery Aneurysms Following Stenting","authors":"Immaneni Sathyamurthy, Kanthallu Narayanamoorthy Srinivasan, Sasikala Subramanian","doi":"10.4103/jicc.jicc_9_22","DOIUrl":"https://doi.org/10.4103/jicc.jicc_9_22","url":null,"abstract":"Coronary artery aneurysms are rare complications following stenting and were reported with drug-eluting as well as bare metal stents. They can be asymptomatic or present as acute coronary syndromes and usually detected during coronary angiography. The mechanisms responsible can be vascular trauma, hypersensitivity to drug, polymer, or metal. Rarely, it can be due to acute bacterial infections resulting in mycotic aneurysms. Management depends on symptoms, presentation, and underlying pathology and has to be tailored on a case-to-case basis.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cessation of pulmonary vasodilators in PAH related to congenital heart disease 与先天性心脏病相关的肺动脉高压患者肺血管扩张剂停用
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_23_22
I. Sathyamurthy, K. Kirubakaran, Sasikala Subramanian, K. Srinivasan
Pulmonary arterial hypertension secondary to congenital heart diseases is a subset of patients who need pulmonary vasodilators (PVDs). We are reporting an adult female who continued to have severe pulmonary hypertension after corrective surgery for the atrial septal defect. She showed improvement in symptoms and effort tolerance assessed by 6-min walk distance, but on cessation of therapy, showed worsening of exercise tolerance which improved after reintroduction. This report stresses the importance of the need for long-term combination of PVDs without interruption.
继发于先天性心脏病的肺动脉高压是需要肺血管扩张剂(pvd)的患者的一个子集。我们报告了一位成年女性,她在房间隔缺损矫正手术后仍然有严重的肺动脉高压。通过6分钟步行距离评估,患者的症状和耐量有所改善,但停止治疗后,运动耐量恶化,重新引入治疗后有所改善。本报告强调了不间断长期联合使用PVDs的重要性。
{"title":"Cessation of pulmonary vasodilators in PAH related to congenital heart disease","authors":"I. Sathyamurthy, K. Kirubakaran, Sasikala Subramanian, K. Srinivasan","doi":"10.4103/jicc.jicc_23_22","DOIUrl":"https://doi.org/10.4103/jicc.jicc_23_22","url":null,"abstract":"Pulmonary arterial hypertension secondary to congenital heart diseases is a subset of patients who need pulmonary vasodilators (PVDs). We are reporting an adult female who continued to have severe pulmonary hypertension after corrective surgery for the atrial septal defect. She showed improvement in symptoms and effort tolerance assessed by 6-min walk distance, but on cessation of therapy, showed worsening of exercise tolerance which improved after reintroduction. This report stresses the importance of the need for long-term combination of PVDs without interruption.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"37 1","pages":"40 - 42"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80333918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Triple-Vessel Coronary Artery Aneurysms Following Drug-Eluting Stents 药物洗脱支架后的三支冠状动脉动脉瘤
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_47_21
Immaneni Sathyamurthy, K. Kirubakaran, Kanthallu Narayanamoorthy Srinivasan, Sasikala Subramanian
Coronary artery aneurysms (CAAs) after drug-eluting stents are rare. They can be found during routine angiograms when asymptomatic or present with acute coronary syndromes. We report a case of multiple CAAs who presented 8 years after the initial stenting. Left anterior descending artery was the culprit vessel and managed with restenting.
冠脉动脉瘤(CAAs)后药物洗脱支架是罕见的。当无症状或伴有急性冠状动脉综合征时,可在常规血管造影中发现。我们报告一例在初次支架植入术后8年出现的多发性CAAs病例。左前降支为罪魁祸首血管,并进行了再灌注。
{"title":"Triple-Vessel Coronary Artery Aneurysms Following Drug-Eluting Stents","authors":"Immaneni Sathyamurthy, K. Kirubakaran, Kanthallu Narayanamoorthy Srinivasan, Sasikala Subramanian","doi":"10.4103/jicc.jicc_47_21","DOIUrl":"https://doi.org/10.4103/jicc.jicc_47_21","url":null,"abstract":"Coronary artery aneurysms (CAAs) after drug-eluting stents are rare. They can be found during routine angiograms when asymptomatic or present with acute coronary syndromes. We report a case of multiple CAAs who presented 8 years after the initial stenting. Left anterior descending artery was the culprit vessel and managed with restenting.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interpreting high sensitivity troponins in various acute clinical settings – Increased significance to the present-day cardiologist 解释高敏感性肌钙蛋白在各种急性临床设置-增加对当今心脏病专家的意义
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_14_21
Raghuram Palaparti, Gopala Koduru, Sarada Chowdary Parvathaneni
High-sensitivity cardiac troponins expedite the evaluation of patients with chest pain in the emergency department. The utility of troponins extends beyond the acute coronary syndromes to accurate the diagnosis of myocardial injury. Troponins are best friends for physicians; however, they are a double-edged sword if not interpreted appropriately. Misdiagnosis is harmful with regard to patient outcomes. The present review focuses on the recent updates in the understanding and interpretation of high-sensitivity troponins in various acute clinical settings. Common mistakes and gray zones in the interpretation of troponins, the concept of myocardial injury versus infarction, newer entities like myocardial infarction (MI) with Nonobstructive Coronary Arteries, recent controversies over the definition of periprocedural MI, complementary role of imaging in the diagnosis of myocardial injury and the role of troponins in the current COVID-19 pandemic are discussed.
高灵敏度心肌肌钙蛋白加快了对急诊科胸痛患者的评估。肌钙蛋白的应用范围超出了急性冠状动脉综合征,可用于准确诊断心肌损伤。肌钙蛋白是医生最好的朋友;然而,如果解释不当,它们是一把双刃剑。误诊对病人的预后是有害的。目前的综述集中在了解和解释高敏感性肌钙蛋白在各种急性临床设置的最新进展。本文讨论了肌钙蛋白解释中的常见错误和灰色地带、心肌损伤与梗死的概念、非阻塞性冠状动脉心肌梗死(MI)等较新的实体、围绕术中心肌梗死定义的近期争议、成像在心肌损伤诊断中的补充作用以及肌钙蛋白在当前COVID-19大流行中的作用。
{"title":"Interpreting high sensitivity troponins in various acute clinical settings – Increased significance to the present-day cardiologist","authors":"Raghuram Palaparti, Gopala Koduru, Sarada Chowdary Parvathaneni","doi":"10.4103/jicc.jicc_14_21","DOIUrl":"https://doi.org/10.4103/jicc.jicc_14_21","url":null,"abstract":"High-sensitivity cardiac troponins expedite the evaluation of patients with chest pain in the emergency department. The utility of troponins extends beyond the acute coronary syndromes to accurate the diagnosis of myocardial injury. Troponins are best friends for physicians; however, they are a double-edged sword if not interpreted appropriately. Misdiagnosis is harmful with regard to patient outcomes. The present review focuses on the recent updates in the understanding and interpretation of high-sensitivity troponins in various acute clinical settings. Common mistakes and gray zones in the interpretation of troponins, the concept of myocardial injury versus infarction, newer entities like myocardial infarction (MI) with Nonobstructive Coronary Arteries, recent controversies over the definition of periprocedural MI, complementary role of imaging in the diagnosis of myocardial injury and the role of troponins in the current COVID-19 pandemic are discussed.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"76 5 Pt 1 1","pages":"1 - 10"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77510889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Left Ventricular Global Longitudinal Strain and Angiographically Derived SYNTAX Score in Patients of Stable Angina Pectoris 稳定性心绞痛患者左心室整体纵向应变与血管造影衍生句法评分的相关性
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_31_22
Suhas Hardas, Shripal Bhivaskar, Hasmukh Gujar, Deepak Sadashiv Phalgune
Background: The present study aimed to assess the relationship between global longitudinal strain (GLS) by two-dimensional (2D) speckle tracking echocardiography (STE) and SYNTAX score (SS) in patients with stable angina pectoris and normal baseline left ventricular (LV) function. Methods: Fifty patients aged ≥18 years presented with stable angina pectoris with LV ejection fraction ≥60.0% posted for elective coronary angiography were included in the study. All the patients underwent 2D echocardiography, 2D STE, and coronary angiography. GLS and SSs were calculated. The primary objective was to find the correlation between GLS and SS in assessing the severity of coronary artery disease (CAD), whereas the secondary objectives were to find the sensitivity and specificity of GLS to predict critical CAD. Results: A significant negative correlation (−0.862, P = 0.001) was observed between GLS and SSs. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of GLS score 16 were 100.0%, 64.0%, 73.5%, 100.0%, and 82.0, respectively, in predicting higher SS (≥22). The mean GLS values were significantly higher in noncritical CAD (16.4 ± 1.1) as compared to critical CAD (12.4 ± 1.3). Conclusions: GLS is a useful noninvasive tool to detect the severity of CAD.
背景:本研究旨在通过二维(2D)斑点跟踪超声心动图(STE)评估总体纵向应变(GLS)和SYNTAX评分(SS)在稳定型心绞痛和正常左室(LV)基线功能患者中的关系。方法:选择50例年龄≥18岁、左室射血分数≥60.0%的稳定型心绞痛患者,择期行冠状动脉造影。所有患者均行二维超声心动图、二维超声心动图和冠状动脉造影。计算GLS和SSs。主要目的是发现GLS和SS在评估冠状动脉疾病(CAD)严重程度方面的相关性,而次要目的是发现GLS预测临界CAD的敏感性和特异性。结果:GLS与SSs呈显著负相关(- 0.862,P = 0.001)。GLS评分16预测高SS(≥22)的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为100.0%、64.0%、73.5%、100.0%和82.0。非临界CAD患者GLS平均值(16.4±1.1)明显高于临界CAD患者(12.4±1.3)。结论:GLS是检测冠心病严重程度的一种有效的无创工具。
{"title":"Correlation of Left Ventricular Global Longitudinal Strain and Angiographically Derived SYNTAX Score in Patients of Stable Angina Pectoris","authors":"Suhas Hardas, Shripal Bhivaskar, Hasmukh Gujar, Deepak Sadashiv Phalgune","doi":"10.4103/jicc.jicc_31_22","DOIUrl":"https://doi.org/10.4103/jicc.jicc_31_22","url":null,"abstract":"Background: The present study aimed to assess the relationship between global longitudinal strain (GLS) by two-dimensional (2D) speckle tracking echocardiography (STE) and SYNTAX score (SS) in patients with stable angina pectoris and normal baseline left ventricular (LV) function. Methods: Fifty patients aged ≥18 years presented with stable angina pectoris with LV ejection fraction ≥60.0% posted for elective coronary angiography were included in the study. All the patients underwent 2D echocardiography, 2D STE, and coronary angiography. GLS and SSs were calculated. The primary objective was to find the correlation between GLS and SS in assessing the severity of coronary artery disease (CAD), whereas the secondary objectives were to find the sensitivity and specificity of GLS to predict critical CAD. Results: A significant negative correlation (−0.862, P = 0.001) was observed between GLS and SSs. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of GLS score 16 were 100.0%, 64.0%, 73.5%, 100.0%, and 82.0, respectively, in predicting higher SS (≥22). The mean GLS values were significantly higher in noncritical CAD (16.4 ± 1.1) as compared to critical CAD (12.4 ± 1.3). Conclusions: GLS is a useful noninvasive tool to detect the severity of CAD.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Admission Platelet Count and B-type Natriuretic Peptide in Predicting in Hospital Morbidity in ST-Elevation Myocardial Infarction Patients 入院血小板计数和b型利钠肽对st段抬高型心肌梗死患者住院发病率的预测作用
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_15_21
Elshaimaa Aly M. Elsadek Seaoud, Mohamed Salah Abdelbasit, Baher Nabil, Ahmed Shawky
Context: Platelets play a major role in the pathophysiology of acute myocardial infarction. Aim: This study aims to evaluate the potential correlation between admission platelet count (PLT) and B-type natriuretic peptide (BNP) with the development of severe heart failure during the first 24 h post primary PCI (post-PPCI) in patients admitted with ST-elevation myocardial infarction (STEMI). Settings and Design: This was cross-sectional follow-up study. Methods: One hundred and forty-six patients admitted with STEMI. At the time of admission, blood samples were drawn to measure PLT and BNP level. Twenty-four h after reperfusion, patients were assessed using Killip score, and a transthoracic echo was done to determine ejection fraction (EF) using modified Simpson’s rule. Statistical Analysis: Comparison between parametric quantitative independent groups done by t -test. The area under the receiver operating characteristic (ROC) area under the curve was calculated to determine the sensitivity and specificity of PLT in diagnosing severe heart failure (Killip III and IV) Confounding bias has been addressed through a multivariate logistic regression model. Results: we found a significant negative correlation between admission PLT and left ventricular EF measured 24 h post-PPCI and a positive correlation between PLT and both BNP and CKMB level measured at admission ( P = 0.001, 0.004 and P = 0.007, respectively). ROC curve analysis showed a platelet cut-off value of 290 × 10 3 to diagnose severe heart failure (Killip’s grades III and IV) (sensitivity of 70% and specificity of 83.1%.). Conclusion: BNP and PLT are easy, inexpensive blood tests that can be used as predictors of heart failure post-STEMI.
背景:血小板在急性心肌梗死的病理生理中起着重要作用。目的:本研究旨在评估st段抬高型心肌梗死(STEMI)患者首次PCI (post- ppci)后24小时内入院血小板计数(PLT)和b型利钠肽(BNP)与严重心力衰竭发展的潜在相关性。设置与设计:本研究为横断面随访研究。方法:146例STEMI住院患者。入院时抽血检测PLT和BNP水平。再灌注24 h后,采用Killip评分评估患者,并采用改进的Simpson规则进行经胸回声测定射血分数(EF)。统计分析:参数定量独立组间比较采用t检验。计算受试者工作特征(ROC)曲线下面积,以确定PLT诊断严重心力衰竭的敏感性和特异性(Killip III和IV)。通过多变量logistic回归模型解决了混杂偏差。结果:我们发现入院时PLT与ppci后24 h左室EF呈显著负相关,PLT与入院时BNP和CKMB水平呈正相关(P分别为0.001、0.004和P = 0.007)。ROC曲线分析显示,血小板临界值为290 × 103诊断严重心力衰竭(Killip分级III级和IV级)(敏感性为70%,特异性为83.1%)。结论:BNP和PLT是一种简单、廉价的血液检测,可作为stemi后心力衰竭的预测指标。
{"title":"The Role of Admission Platelet Count and B-type Natriuretic Peptide in Predicting in Hospital Morbidity in ST-Elevation Myocardial Infarction Patients","authors":"Elshaimaa Aly M. Elsadek Seaoud, Mohamed Salah Abdelbasit, Baher Nabil, Ahmed Shawky","doi":"10.4103/jicc.jicc_15_21","DOIUrl":"https://doi.org/10.4103/jicc.jicc_15_21","url":null,"abstract":"Context: Platelets play a major role in the pathophysiology of acute myocardial infarction. Aim: This study aims to evaluate the potential correlation between admission platelet count (PLT) and B-type natriuretic peptide (BNP) with the development of severe heart failure during the first 24 h post primary PCI (post-PPCI) in patients admitted with ST-elevation myocardial infarction (STEMI). Settings and Design: This was cross-sectional follow-up study. Methods: One hundred and forty-six patients admitted with STEMI. At the time of admission, blood samples were drawn to measure PLT and BNP level. Twenty-four h after reperfusion, patients were assessed using Killip score, and a transthoracic echo was done to determine ejection fraction (EF) using modified Simpson’s rule. Statistical Analysis: Comparison between parametric quantitative independent groups done by t -test. The area under the receiver operating characteristic (ROC) area under the curve was calculated to determine the sensitivity and specificity of PLT in diagnosing severe heart failure (Killip III and IV) Confounding bias has been addressed through a multivariate logistic regression model. Results: we found a significant negative correlation between admission PLT and left ventricular EF measured 24 h post-PPCI and a positive correlation between PLT and both BNP and CKMB level measured at admission ( P = 0.001, 0.004 and P = 0.007, respectively). ROC curve analysis showed a platelet cut-off value of 290 × 10 3 to diagnose severe heart failure (Killip’s grades III and IV) (sensitivity of 70% and specificity of 83.1%.). Conclusion: BNP and PLT are easy, inexpensive blood tests that can be used as predictors of heart failure post-STEMI.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Electrocardiogram Changes with Epicardial and Myocardial Perfusion in ST-Elevation Myocardial Infarction st段抬高型心肌梗死心电图变化与心外膜及心肌灌注的相关性
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_31_23
Mahesh Kharade, Sunil Sathe, Deepak Sadashiv Phalgune, Hasmukh Gujar, Mullasari Ajit Sankardas
Background: The present study was aimed to find the correlation of electrocardiographic changes with epicardial thrombolysis in myocardial infarction (TIMI) flow grade and TIMI myocardial perfusion grade (TMPG) after reperfusion in ST-elevation myocardial infarction (STEMI). Methods: One hundred and fifty patients with STEMI were included. Reperfusion was done either by thrombolysis or primary percutaneous coronary intervention. The summed absolute ST-segment deviation and summed relative ST-segment deviation were calculated. TIMI and TMPG were assessed. The primary outcome measures were to study the correlation of summed absolute ST deviation and summed relative ST deviation with TIMI flow grade and TMPG after reperfusion. The secondary outcome measures were to compare TIMI flow grade and TMPG with respect to time since symptom onset to treatment and T-wave inversion after reperfusion. Results: There was a significant positive correlation between relative ST-segment deviation that occurred after reperfusion with TIMI flow grade ( r = 0.475) and TMPG ( r = 0.376). There was a significant negative correlation between absolute ST-segment deviation that occurred after reperfusion with TIMI flow grade ( r = −0.194) and TMPG ( r = −0.288). A significantly higher percentage (87.4%) of patients who got treatment within 1 h showed TMPG 2 and 3. A significantly higher percentage of patients who had T-wave inversion after reperfusion had TIMI flow Grade 3 and TMPG 2 and 3. Conclusions: There was a significant positive correlation between relative ST-segment deviation and significant negative correlation between absolute ST-segment deviation after reperfusion with TIMI flow grade and TMPG.
背景:本研究旨在探讨st段抬高型心肌梗死(STEMI)再灌注后心外膜溶栓(TIMI)血流等级和TIMI心肌灌注等级(TMPG)与心电图变化的相关性。方法:纳入150例STEMI患者。再灌注通过溶栓或经皮冠状动脉介入治疗进行。计算绝对st段偏差求和和相对st段偏差求和。评估TIMI和TMPG。主要观察指标为再灌注后TIMI血流等级和TMPG与总绝对ST差和总相对ST差的相关性。次要结局指标是比较TIMI血流等级和TMPG从症状出现到治疗的时间以及再灌注后t波反转。结果:再灌注后相对st段偏移与TIMI血流等级(r = 0.475)与TMPG (r = 0.376)呈正相关。再灌注后st段绝对偏移与TIMI血流等级(r = - 0.194)和TMPG (r = - 0.288)呈显著负相关。在1 h内接受治疗的患者中,TMPG 2和3的比例明显高于对照组(87.4%)。再灌注后出现t波倒置的患者TIMI血流3级,TMPG 2级和3级的比例明显更高。结论:TIMI血流分级与TMPG再灌注后相对st段偏度呈显著正相关,绝对st段偏度呈显著负相关。
{"title":"Correlation of Electrocardiogram Changes with Epicardial and Myocardial Perfusion in ST-Elevation Myocardial Infarction","authors":"Mahesh Kharade, Sunil Sathe, Deepak Sadashiv Phalgune, Hasmukh Gujar, Mullasari Ajit Sankardas","doi":"10.4103/jicc.jicc_31_23","DOIUrl":"https://doi.org/10.4103/jicc.jicc_31_23","url":null,"abstract":"Background: The present study was aimed to find the correlation of electrocardiographic changes with epicardial thrombolysis in myocardial infarction (TIMI) flow grade and TIMI myocardial perfusion grade (TMPG) after reperfusion in ST-elevation myocardial infarction (STEMI). Methods: One hundred and fifty patients with STEMI were included. Reperfusion was done either by thrombolysis or primary percutaneous coronary intervention. The summed absolute ST-segment deviation and summed relative ST-segment deviation were calculated. TIMI and TMPG were assessed. The primary outcome measures were to study the correlation of summed absolute ST deviation and summed relative ST deviation with TIMI flow grade and TMPG after reperfusion. The secondary outcome measures were to compare TIMI flow grade and TMPG with respect to time since symptom onset to treatment and T-wave inversion after reperfusion. Results: There was a significant positive correlation between relative ST-segment deviation that occurred after reperfusion with TIMI flow grade ( r = 0.475) and TMPG ( r = 0.376). There was a significant negative correlation between absolute ST-segment deviation that occurred after reperfusion with TIMI flow grade ( r = −0.194) and TMPG ( r = −0.288). A significantly higher percentage (87.4%) of patients who got treatment within 1 h showed TMPG 2 and 3. A significantly higher percentage of patients who had T-wave inversion after reperfusion had TIMI flow Grade 3 and TMPG 2 and 3. Conclusions: There was a significant positive correlation between relative ST-segment deviation and significant negative correlation between absolute ST-segment deviation after reperfusion with TIMI flow grade and TMPG.","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"275 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To Compare the Effects of Adding Handheld and Ankle Weights During Treadmill Walking on Blood Pressure and Rate of Perceived Exertion in Normal Healthy Adults: An Experimental Study 比较在跑步机上增加手持式和踝关节重量对正常健康成人血压和感知用力率的影响:一项实验研究
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_19_23
Kavita Vilas Pande, Madhuri Rushikesh Joshi, Rushikesh Kaushik Joshi
Context: Walking is the most commonly reported activity which requires no special facilities and is achievable by all groups with little injury risk. Nowadays, adding weights to different locations while walking is popular in general fitness and rehabilitation programs, which again increases energy expenditure as well as oxygen consumption in a shorter quantity of time. Aims: The aim of this study was to compare the effect of adding handheld and ankle weights during treadmill walking on blood pressure and rate of perceived exertion in normal healthy adults. Settings and Design: The experimental study took place in the laboratory and was designed to be carried on for three sessions to measure the changes in blood pressure and ratings of perceived exertion (RPE) while walking with and without weight. Subjects and Methods: Thirty-three participants who satisfied the inclusion criteria were recruited to perform the exercise session with handheld and ankle and without weights and it consisted of 8 min of exercise testing with and without weights for two sessions. Statistical Analysis Used: The statistical test data were screened for normal distribution by Shapiro–Wilk test. Data were normally distributed for the systolic blood pressure (SBP), diastolic blood pressure (DBP), and RPE. Hence, parametric tests were applied for SBP, DBP, and RPE within-session and between-session analysis. Within-session analysis was done by paired t -test and between-session analysis was done by unpaired t -test. Results: Intra-session analysis by paired t -test in both sessions shows statistically significant changes in SBP and RPE ( P < 0.05). Moreover, DBP was found significant while using handheld weights compared to no weights. While inter-session analysis by unpaired t -test showed significant changes in DBP compared to that of SBP, RPE using handheld weights during treadmill walking. Conclusions: Study shows addition of handheld weights proves to be more effective in adults who cannot run, or do not like to run, or are limited in walking speed, and may benefit from the addition of hand-held weight (HHW) and ankle weight (AW).
背景:步行是最常见的不需要特殊设施的活动,所有人群都可以进行,而且受伤风险很小。如今,在散步时增加不同位置的重量在一般健身和康复计划中很受欢迎,这再次增加了能量消耗和氧气消耗,在更短的时间内。目的:本研究的目的是比较在跑步机上增加手持和脚踝重量对正常健康成年人血压和感知劳累率的影响。环境和设计:实验研究在实验室进行,设计为进行三个阶段,以测量血压和感知运动等级(RPE)在负重和不负重行走时的变化。对象和方法:招募33名符合纳入标准的参与者进行手持和踝关节无负重运动,包括8分钟的负重和无负重运动测试,为期两个阶段。统计分析方法:统计检验资料采用Shapiro-Wilk检验,筛选为正态分布。收缩压(SBP)、舒张压(DBP)和RPE数据呈正态分布。因此,参数检验应用于会话内和会话间的收缩压、舒张压和RPE分析。会话内分析采用配对t检验,会话间分析采用非配对t检验。结果:两组患者的会话内配对t检验分析显示,SBP和RPE的变化具有统计学意义(P <0.05)。此外,与不使用重量相比,使用手持重量时发现DBP显着。而非配对t检验的间歇分析显示,与在跑步机上使用手持重量的RPE相比,舒张压有显著变化。结论:研究表明,对于不能跑步或不喜欢跑步或步行速度有限的成年人,增加手持重量被证明是更有效的,并且可能从增加手持重量(HHW)和脚踝重量(AW)中受益。
{"title":"To Compare the Effects of Adding Handheld and Ankle Weights During Treadmill Walking on Blood Pressure and Rate of Perceived Exertion in Normal Healthy Adults: An Experimental Study","authors":"Kavita Vilas Pande, Madhuri Rushikesh Joshi, Rushikesh Kaushik Joshi","doi":"10.4103/jicc.jicc_19_23","DOIUrl":"https://doi.org/10.4103/jicc.jicc_19_23","url":null,"abstract":"Context: Walking is the most commonly reported activity which requires no special facilities and is achievable by all groups with little injury risk. Nowadays, adding weights to different locations while walking is popular in general fitness and rehabilitation programs, which again increases energy expenditure as well as oxygen consumption in a shorter quantity of time. Aims: The aim of this study was to compare the effect of adding handheld and ankle weights during treadmill walking on blood pressure and rate of perceived exertion in normal healthy adults. Settings and Design: The experimental study took place in the laboratory and was designed to be carried on for three sessions to measure the changes in blood pressure and ratings of perceived exertion (RPE) while walking with and without weight. Subjects and Methods: Thirty-three participants who satisfied the inclusion criteria were recruited to perform the exercise session with handheld and ankle and without weights and it consisted of 8 min of exercise testing with and without weights for two sessions. Statistical Analysis Used: The statistical test data were screened for normal distribution by Shapiro–Wilk test. Data were normally distributed for the systolic blood pressure (SBP), diastolic blood pressure (DBP), and RPE. Hence, parametric tests were applied for SBP, DBP, and RPE within-session and between-session analysis. Within-session analysis was done by paired t -test and between-session analysis was done by unpaired t -test. Results: Intra-session analysis by paired t -test in both sessions shows statistically significant changes in SBP and RPE ( P < 0.05). Moreover, DBP was found significant while using handheld weights compared to no weights. While inter-session analysis by unpaired t -test showed significant changes in DBP compared to that of SBP, RPE using handheld weights during treadmill walking. Conclusions: Study shows addition of handheld weights proves to be more effective in adults who cannot run, or do not like to run, or are limited in walking speed, and may benefit from the addition of hand-held weight (HHW) and ankle weight (AW).","PeriodicalId":100789,"journal":{"name":"Journal of Indian College of Cardiology","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Indian College of Cardiology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1