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Feasibility and Safety of Optical Coherence Tomography-Guided Percutaneous Coronary Intervention in Technically Challenging Lesions: A Case Series 光学相干层析引导下经皮冠状动脉介入治疗具有技术挑战性病变的可行性和安全性:一个病例系列
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_67_21
Rajesh Pandey
Optical coherence tomography (OCT) has better resolution than that of intravascular ultrasound. OCT provides vital information during percutaneous coronary intervention (PCI) procedure and is associated with better procedural and inhospital outcomes along with improved survival rate. In the present article, we have investigated three special cases including anomalous separate origin of the left circumflex artery at our hospital. We have reported the feasibility and safety of OCT-guided PCI in these three cases.
光学相干断层扫描(OCT)比血管内超声具有更好的分辨率。OCT在经皮冠状动脉介入治疗(PCI)过程中提供重要信息,并与更好的手术和住院结果以及提高的生存率相关。在本文中,我们调查了三个特殊的情况下,包括异常分离起源的左旋动脉在我们的医院。我们已经报道了这三例oct引导下PCI的可行性和安全性。
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引用次数: 0
Multistaged closure of bilateral multiple pulmonary arteriovenous fistula 双侧多发性肺动静脉瘘多阶段闭合术
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_57_21
M. Panja, M. Panja, A. Singhi
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引用次数: 0
Autonomic functions in hypothyroidism 甲状腺功能减退的自主神经功能
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_15_22
A. Jose, Roshan Maroli, P. George
Background: Hypothyroidism is a common endocrine disorder in the general population. Most of the cardiovascular and neurological manifestations of hypothyroidism are due to autonomic dysfunction. The American Academy of Neurology has recommended simple bedside autonomic function tests for the diagnosis and follow-up of autonomic functions. Recognition of autonomic dysfunction and treatment of hypothyroidism may improve cardiovascular outcomes. This study aims to assess autonomic dysfunction in hypothyroidism and correlate it with serum thyroid-stimulating hormone (TSH) levels. Materials and Methods: This cross-sectional study was conducted on 60 patients diagnosed with hypothyroidism for 12 months at a tertiary care center in Southern India. Patients with a Zulewski clinical score over 5 and fulfilling the selection criteria were included in the study after obtaining written informed consent. Details of history, treatment, examination, and thyroid function tests data were collected and bedside tests for autonomic functions were performed. Results: Ninety percent of individuals were female, and the average age of the included study population was 40.38 ± 11.78 years. Based on TSH and FT4 values, the patients were subgrouped into currently euthyroid and overt hypothyroid individuals. The majority of the individuals (81.67%) included in the study had autonomic dysfunction. Based on the autonomic dysfunction score, there was a significantly higher proportion of overt hypothyroid individuals (n = 18) with severe autonomic dysfunction compared to euthyroid individuals (n = 4). About 75% of the study individuals had sympathetic dysfunction and 66.7% of individuals had parasympathetic dysfunction. There was no statistically significant association between autonomic dysfunction and the duration of hypothyroidism. Conclusion: Autonomic dysfunction in hypothyroidism is common; sympathetic dysfunction was observed more as compared to parasympathetic dysfunction.
背景:甲状腺功能减退症是普通人群中常见的内分泌疾病。大多数甲状腺功能减退的心血管和神经系统表现是由自主神经功能障碍引起的。美国神经病学学会推荐简单的床边自主神经功能测试用于自主神经功能的诊断和随访。识别自主神经功能障碍和治疗甲状腺功能减退可改善心血管预后。本研究旨在评估甲状腺功能减退患者的自主神经功能障碍及其与血清促甲状腺激素(TSH)水平的相关性。材料和方法:本横断面研究在印度南部一家三级保健中心对60名诊断为甲状腺功能减退的患者进行了为期12个月的研究。Zulewski临床评分大于5分且符合选择标准的患者在获得书面知情同意后被纳入研究。收集病史、治疗、检查和甲状腺功能检查的详细资料,并进行自主神经功能床边检查。结果:90%的个体为女性,纳入研究人群的平均年龄为40.38±11.78岁。根据TSH和FT4值,将患者分为当前甲状腺功能正常和明显甲状腺功能低下两组。纳入研究的大多数个体(81.67%)存在自主神经功能障碍。根据自主神经功能障碍评分,明显的甲状腺功能减退患者(n = 18)有严重自主神经功能障碍的比例明显高于甲状腺功能正常患者(n = 4)。约75%的研究个体有交感神经功能障碍,66.7%的个体有副交感神经功能障碍。自主神经功能障碍与甲状腺功能减退持续时间之间无统计学意义。结论:自主神经功能障碍在甲状腺功能减退症中较为常见;交感神经功能障碍多于副交感神经功能障碍。
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引用次数: 0
Frequency of supraventricular arrhythmias in COVID-19 patients: A single-center study COVID-19患者室上性心律失常频率:一项单中心研究
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_13_22
M. Al-Daydamony, M. El-Shaer, Hany Abdel‐Latif, Moataz El-Sanan
Background: Cardiac arrhythmias had a significant association with the increased mortality rate in COVID-19 patients in hospitals. The present study aimed to evaluate the frequency of supraventricular arrhythmias in COVID-19 patients and to assess the echocardiographic parameters and inflammatory biomarkers in COVID-19 patients who developed supraventricular arrhythmias. Methods: This cross-sectional study enrolled 196 patients, 33 of them developed supraventricular arrhythmias during hospitalization in Zagazig University isolation hospital. Results: There was a statistically significant association between the occurrence of atrial fibrillation (AF) and both oxygen saturation and lymphocyte percentage, which was significantly lower in those with AF. There was a statistically significant association between the occurrence of AF and CORADS, C-reactive protein (CRP), and interleukin-6, which were significantly higher in those with AF. Younger age and higher oxygen saturation decreased the risk of supraventricular tachycardia among the studied patients. Increasing oxygen saturation decreased the risk of AF among the studied patients, while higher CRP significantly increased risk by 1.045 folds. Conclusions: Atrial arrhythmias, especially with AF considered prevalent in cases with COVID-19. The atrial arrhythmias were correlated with higher cardiac injury and inflammatory markers and elevated severe COVID-19 clinical manifestations. Regarding mortality in-hospital, the association between COVID-19 and atrial arrhythmias was independent.
背景:心律失常与医院COVID-19患者死亡率升高有显著相关性。本研究旨在评估COVID-19患者室上心律失常的发生频率,并评估发生室上心律失常的COVID-19患者的超声心动图参数和炎症生物标志物。方法:本横断面研究纳入196例患者,其中33例在扎加齐格大学隔离医院住院期间发生室上性心律失常。结果:房颤(AF)的发生与血氧饱和度、淋巴细胞百分比均有统计学意义相关,房颤患者的血氧饱和度、淋巴细胞百分比明显降低。房颤(AF)的发生与CORADS、c反应蛋白(CRP)、白细胞介素-6有统计学意义相关。在研究的患者中,年龄越小和血氧饱和度越高可降低室上性心动过速的风险。在研究的患者中,血氧饱和度升高降低了房颤的风险,而CRP升高则使房颤的风险显著增加了1.045倍。结论:心房心律失常,特别是房颤被认为在COVID-19病例中普遍存在。心房心律失常与心脏损伤和炎症指标升高以及重症COVID-19临床表现升高相关。关于住院死亡率,COVID-19与心房心律失常之间的关联是独立的。
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引用次数: 0
Four-dimensional XStrain echocardiography: Correlation of aortic stiffness with left ventricular diastolic, systolic, and strain parameters in healthy adults – A single-center Indian perspective 四维XStrain超声心动图:健康成人主动脉硬度与左室舒张、收缩和应变参数的相关性——单中心印度视角
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_30_22
Akhil Mehrotra, Ajay Sharma, M. Shadab, O. Prakash, Shubham Kacker
Background: Interrelationship of arterial stiffness with diastolic impairments of left ventricle (LV) in healthy population has been reported in several studies; however, to the best of our knowledge, no study till date has evaluated the relationship of aortic stiffness, with LV diastolic, systolic, and strain components, in healthy adults, by conventional, tissue Doppler imaging, and speckle-tracking echocardiography. Materials and Methods: Fifty-eight healthy participants were recruited (38 males and 20 females), and their mean age was 30.53 ± 12.22 years and 35.25 ± 10.61 years, respectively. A detailed assessment of aortic stiffness and elasticity, LV systolic, diastolic, and strain parameters was performed by the ingenious technology of four-dimensional XStrain echocardiography. Moreover, Pearson's correlation coefficient was employed to investigate the association of aortic stiffness with LV diastolic, systolic, and strain functions. Results: A significant relationship was documented between aortic stiffness and a number of parameters of LV diastolic and systolic functions. On the contrary, there was an insignificant trend of positive or negative correlation of aortic stiffness with LV strain. Conclusion: This is the first study to document the correlation between aortic stiffness and various LV functions in healthy adults.
背景:在健康人群中,动脉僵硬度与左心室舒张损伤的相互关系已经在一些研究中得到了报道;然而,据我们所知,迄今为止还没有研究通过常规、组织多普勒成像和斑点跟踪超声心动图评估健康成人主动脉僵硬度与左室舒张、收缩和应变成分的关系。材料与方法:招募健康受试者58例(男38例,女20例),平均年龄30.53±12.22岁,35.25±10.61岁。通过巧妙的四维XStrain超声心动图技术,详细评估主动脉硬度和弹性、左室收缩、舒张和应变参数。此外,Pearson相关系数用于研究主动脉硬度与左室舒张、收缩和应变功能的关系。结果:主动脉硬度与左室舒张和收缩功能的一些参数之间有显著的关系。主动脉僵硬度与左室应变的正相关或负相关趋势不显著。结论:这是第一个记录健康成人主动脉僵硬度与各种左室功能之间相关性的研究。
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引用次数: 0
Coronary Dominance Pattern: An Angiography-based Preliminary Report from Eastern India 冠状动脉优势模式:一份来自印度东部的基于血管造影的初步报告
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_14_23
Avishek Bagchi
We did a retrospective analysis of 102 coronary angiograms for coronary dominance. Right-dominant circulation was seen in 62 (60.8%) patients, whereas left-dominant and codominant circulation was seen in 25 (24.5%) and 15 (14.7%) patients, respectively. Regarding gender variations, among males 71.42% had right-dominant circulation, where it was left dominant in 20.63% and codominant in 7.93%. For females, right-dominant circulation was present in 43.59% of patients, and left-dominant and codominant circulation was present in 30.77% and 25.64% of patients, respectively.
我们回顾性分析了102例冠状动脉造影的冠状动脉优势。62例(60.8%)患者出现右优势循环,而左优势循环和共优势循环分别为25例(24.5%)和15例(14.7%)。在性别差异方面,男性血液循环以右为主占71.42%,以左为主占20.63%,共为主占7.93%。女性中,43.59%的患者存在右优势循环,30.77%的患者存在左优势循环,25.64%的患者存在共优势循环。
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引用次数: 0
Impact of percutaneous coronary intervention in the right coronary artery on right ventricular function in patients with acute myocardial infarction 经皮冠状动脉介入治疗对急性心肌梗死患者右心室功能的影响
Pub Date : 2023-01-01 DOI: 10.4103/jicc.jicc_16_22
GanthalaPaul Kiran, T. Santosh, Grace John, MSrinivasa Rao
Background: Right ventricular (RV) dysfunction is a potent predictor of mortality and morbidity after acute myocardial infarction (MI). Even though elective percutaneous coronary intervention (PCI) has significantly decreased myocardial damage of the left ventricle; in literature, there has been a lack of information regarding the effect of PCI on RV function. Objective: The objective of this study is to examine the effect of the right coronary artery (RCA) revascularization on systolic and diastolic functions of the right ventricle following acute inferior wall MI (IWMI). Subjects and Methods: Fifty-nine patients diagnosed with acute IWMI following RCA revascularization were prospectively investigated between April 2018 and January 2020. Patients were subjected to two-dimensional echocardiography. RV systolic and diastolic functions were reported before and after the PCI procedure and compared using different echocardiographic RV systolic and diastolic parameters. Results: After PCI, echocardiographic RV systolic and diastolic functions were significantly improved in proximal and mid RCA in terms of tricuspid annular plane systolic excursion (TAPSE), RV fractional area change (RVFAC), and early RV filling velocity/late RV filling velocity (E/A). Significant improvement was found in mid RCA in terms of peak systolic (S') velocity (P = 0.008) and proximal RCA in terms of early RV filling velocity/early diastolic tricuspid annulus velocity (E/e') (P = 0.021). Overall echocardiographic systolic and diastolic parameters in patients with RV dysfunction following PCI were improved (TAPSE [37.29% vs. 81.82%], S' velocity [37.29% vs. 68.18%], RVFAC [33.90% vs. 90.00%], and E/A [33.90% vs. 75.00%]). Conclusions: Patients with RV dysfunction were remarkably improved after RCA revascularization. Hence, RCA revascularization can become an appropriate treatment alternative for the recovery of patients who suffer from RV dysfunction.
背景:右心室功能障碍是急性心肌梗死(MI)后死亡率和发病率的有效预测因子。尽管选择性经皮冠状动脉介入治疗(PCI)显著降低了左心室的心肌损伤;在文献中,缺乏关于PCI对RV功能影响的信息。目的:探讨急性下壁心肌梗死(IWMI)后右冠状动脉(RCA)血运重建术对右心室收缩和舒张功能的影响。对象和方法:在2018年4月至2020年1月期间,对59例经RCA血运重建术诊断为急性IWMI的患者进行前瞻性调查。患者接受二维超声心动图检查。报告PCI手术前后左室收缩和舒张功能,并使用不同的超声心动图右室收缩和舒张参数进行比较。结果:PCI术后,超声心动图右心室收缩和舒张功能在三尖瓣环面收缩偏移(TAPSE)、右心室分数面积改变(RVFAC)和早期右心室充盈速度/晚期右心室充盈速度(E/A)方面均显著改善。中期RCA在峰值收缩速度(S')方面有显著改善(P = 0.008),近端RCA在早期RV充盈速度/舒张早期三尖瓣环速度(E/ E ')方面有显著改善(P = 0.021)。左室功能障碍患者PCI术后超声心动图收缩期和舒张期总参数均有改善(TAPSE [37.29% vs. 81.82%], S' velocity [37.29% vs. 68.18%], RVFAC [33.90% vs. 90.00%], E/A [33.90% vs. 75.00%])。结论:RCA血运重建术后右心室功能障碍患者有明显改善。因此,RCA血运重建术可以成为右心室功能障碍患者康复的一种合适的治疗选择。
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引用次数: 0
Challenges in the implementation of telemedicine 远程医疗实施中的挑战
Pub Date : 2022-10-01 DOI: 10.4103/jicc.jicc_22_21
P. Raju, Prasad Sistla
Background: There is a constant search across the globe for optimal healthcare solutions with affordability, accessibility, availability, and quality of healthcare services being the burning issue for mankind. The pandemic has further necessitated the need of use of the Telemedicine platform to address healthcare issues which are also non Covid related. Though Telemedicine has been in use for over two decades in India, there have been various challenges and adoption issues which have not yet made the technology an effective solution to address the current healthcare issues. There has been phenomenal growth in the Information and Communication Technology (ICT) over the last decade and its utilization in the healthcare field. Methods: Internet research on the various adoption strategies by healthcare providers coupled with our own experience for using this technology along with guidelines provided by the information and communication technology providers. The Telemedicine Guidelines of 2020 released by the Ministry of Health and Family welfare, India, provides a framework for the implementation of healthcare delivery through this technology. Results: This paper mentions our telemedicine experience in governmental and private institutes and highlights the implementation challenges of this technology and some solutions that made a difference in the execution. However, we discuss to a larger extent the possible challenges and barriers in the implementation of this technology in India. Conclusion: Despite successful work in the field of telemedicine, it is yet to become an integral part of healthcare system because challenges related to adaptability of healthcare users and lack of proper training to fast growing technologies. The future is going to compel the usage of this kind of technology and it is essential for setting up infrastructure and having trained personnel to man these departments to encash the full potential of the telemedicine technology.
背景:在全球范围内,人们一直在寻找最佳的医疗保健解决方案,医疗保健服务的可负担性、可及性、可用性和质量是人类面临的紧迫问题。大流行进一步需要使用远程医疗平台来解决与Covid无关的医疗保健问题。尽管远程医疗在印度已经使用了二十多年,但仍存在各种挑战和采用问题,这些问题尚未使该技术成为解决当前医疗保健问题的有效解决方案。在过去十年中,信息和通信技术(ICT)及其在医疗保健领域的应用取得了惊人的增长。方法:通过互联网研究医疗保健提供者的各种采用策略,结合我们自己使用该技术的经验以及信息和通信技术提供者提供的指导方针。印度卫生和家庭福利部发布的《2020年远程医疗指南》为通过该技术实施医疗服务提供了一个框架。结果:本文提到了我们在政府和私人机构的远程医疗经验,并强调了该技术的实施挑战和一些在执行中产生差异的解决方案。然而,我们在更大程度上讨论了在印度实施这项技术可能面临的挑战和障碍。结论:尽管远程医疗领域的工作取得了成功,但由于医疗保健用户的适应性和缺乏对快速发展的技术的适当培训,远程医疗尚未成为医疗保健系统的组成部分。未来将迫使这种技术的使用,建立基础设施和训练有素的人员来管理这些部门,以充分发挥远程医疗技术的潜力是至关重要的。
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引用次数: 0
Prevalence of metabolic syndrome and its clinical and angiographic profile in patients with naive acute coronary syndrome 原发性急性冠脉综合征患者代谢综合征的患病率及其临床和血管造影特征
Pub Date : 2022-10-01 DOI: 10.4103/jicc.jicc_64_21
Anil Kumar, P. Surhonne, R. Reddy, M. Nanjappa
Objective: The objective of the study is to evaluate the prevalence of metabolic syndrome (MS) and its clinical and angiographic profile in patients with naive acute coronary syndrome (ACS). Furthermore, this study tried to evaluate the severity of coronary artery disease in patients with and without MS. Methods: This was a single-center, cross-sectional study which prospectively enrolled 500 patients with naive ACS during the period from January 2017 to December 2018 at a tertiary care center in India. They were divided into two groups according to the presence and absence of MS based on revised NCEP ATP III guidelines. The ACS was defined based on the Joint Committee of the American College of Cardiology. After clinical evaluation and investigations, the prevalence of MS in ACS patients was calculated. Results: Prevalence of MS in this study was 46.2% and was more frequent in males (81%) compared to females (19%). Maximum number of patients with MS were between the age group of 40–59 years (55%). Prevalence of diabetes (56.7%), hypertension (58.0%), and smoking (45.88%) were significantly higher in patients with MS (P < 0.001). Most prevalent components of MS were low high-density lipoprotein (HDL) levels, increased blood pressure, fasting blood sugar, and triglyceride levels (P < 0.001). Conclusion: Prevalence of MS was high in patients with ACS and was more often after the age of 40 years and most commonly seen in males. Low HDL levels, increased blood pressure, and blood sugar were most prevalent components in the criteria for MS. Patients with MS tend to have more complex coronary lesions.
目的:本研究的目的是评估代谢综合征(MS)的患病率及其在初发急性冠脉综合征(ACS)患者中的临床和血管造影特征。此外,本研究试图评估患有和不患有ms的患者冠状动脉疾病的严重程度。方法:这是一项单中心横断面研究,在2017年1月至2018年12月期间,在印度的一家三级医疗中心前瞻性地招募了500名原发性ACS患者。根据修订后的NCEP ATP III指南,根据是否存在MS分为两组。ACS是根据美国心脏病学会联合委员会定义的。经临床评估和调查,计算ACS患者中MS的患病率。结果:本研究中多发性硬化症的患病率为46.2%,男性(81%)高于女性(19%)。MS患者的最大数量在40-59岁之间(55%)。糖尿病患病率(56.7%)、高血压患病率(58.0%)、吸烟患病率(45.88%)在多发性硬化症患者中显著升高(P < 0.001)。MS最常见的成分是低高密度脂蛋白(HDL)水平、血压升高、空腹血糖和甘油三酯水平(P < 0.001)。结论:MS在ACS患者中患病率较高,以40岁以后多见,以男性多见。低HDL水平、血压升高和血糖是MS标准中最普遍的组成部分,MS患者往往有更复杂的冠状动脉病变。
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引用次数: 2
Outcomes of Percutaneous Coronary Intervention in the Young 青年人经皮冠状动脉介入治疗的结果
Pub Date : 2022-10-01 DOI: 10.4103/jicc.jicc_8_22
Satya Lakshmi Vanaparty, Lalita Nemani, Jahangir Sheik
Background: The incidence of coronary artery disease in the young is constantly rising. Understanding the outcomes of percutaneous coronary intervention (PCI) in young adults is necessary. This study aims to assess the procedural outcomes, inhospital and 1 year clinical outcomes of PCI in the young (<40-year-old). Methods: This is a prospective, observational study carried out in the Department of Cardiology at Nizam's Institute of Medical Sciences. The study included all subjects ≤40 years of age and has undergone PCI from January 1, 2019 to December 31, 2019 in our institute. Results: The study included 207 patients with a mean age of 36.01 ± 3.72 years and 72.46% males. Acute coronary syndrome was seen in 79.2% patients with ST elevation myocardial infarction (STEMI) being the most common. The median time interval of presentation in STEMI was 12–48 h (73%). Major adverse cardiac events (MACE) over 1-year were seen in 3.8% patients. Severe left ventricular (LV) dysfunction at presentation was an independent factor for acute (P = 0.04) and 1-year mortality (P = 0.0058). It was also associated with angina and chronic heart failure (CHF). Slow flow was significantly associated with mortality (P = 0.0254) and adverse 1 year outcomes. It was significantly associated with persistent LV dysfunction and recurrent CHF. Conclusion: Success rate after PCI is high in the young. 1 year outcome is very good with low mortality and MACE events. Severe LV dysfunction and slow flow are independent predictors of poor prognosis at 1 year.
背景:青年人冠状动脉疾病的发病率不断上升。了解年轻人经皮冠状动脉介入治疗(PCI)的结果是必要的。本研究旨在评估年轻人(<40岁)PCI的手术结果、住院结果和1年临床结果。方法:这是一项在尼扎姆医学科学研究所心内科进行的前瞻性观察性研究。本研究纳入所有年龄≤40岁且于2019年1月1日至2019年12月31日在我院行PCI的受试者。结果:共纳入207例患者,平均年龄36.01±3.72岁,男性占72.46%。急性冠脉综合征发生率为79.2%,ST段抬高型心肌梗死(STEMI)最为常见。STEMI患者出现的中位时间间隔为12-48小时(73%)。1年内主要心脏不良事件(MACE)发生率为3.8%。发病时严重的左心室功能障碍是急性(P = 0.04)和1年死亡率(P = 0.0058)的独立因素。它还与心绞痛和慢性心力衰竭(CHF)有关。血流缓慢与死亡率(P = 0.0254)和不良的1年预后显著相关。它与持续的左室功能障碍和复发的CHF显著相关。结论:青壮年PCI术后成功率高。1年预后非常好,死亡率和MACE事件较低。严重左室功能障碍和血流缓慢是1年预后不良的独立预测因素。
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引用次数: 0
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Journal of Indian College of Cardiology
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