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Thermal analysis system and method of operation 热分析系统和操作方法
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80019-6
Hwang Ming J, Edwards Darvin R
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引用次数: 0
A general robot control system for automatic chemical analysis 用于自动化学分析的通用机器人控制系统
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80005-6
S. Dunkerley, M.J. Adams

Advances in instrumentation have led to increasing interest in automatic chemical analyses. Unfortunately, the potential flexibility of robot systems can often not be exploited because of complex programming languages and poor user-interface. These factors generally limit the use of laboratory robots to a few repetitive tasks. This paper describes the development of a general robot control system for automatic chemical analysis. The program is written in Turbo Pascal and Visual Basic and runs in the Microsoft Windows environment. The analytical workspace is designed by selection of an object's icon followed by its desired orientation. Positioning of this object is then performed using a ‘drag and drop’ procedure. The robotic procedure is set-up by selection of items of apparatus and their associated actions. The performance of the system is demonstrated by the determination for caffeine in tablet formulations using a continuous dilution and calibration scheme.

仪器的进步导致人们对自动化学分析越来越感兴趣。不幸的是,由于复杂的编程语言和糟糕的用户界面,机器人系统的潜在灵活性往往无法得到利用。这些因素通常将实验室机器人的使用限制在少数重复任务上。本文介绍了一种用于自动化学分析的通用机器人控制系统的开发。该程序使用Turbo Pascal和Visual Basic编写,并在Microsoft Windows环境中运行。分析工作空间是通过选择对象的图标和所需的方向来设计的。然后使用“拖放”过程来定位此对象。机器人程序是通过选择设备项目及其相关动作来设置的。该系统的性能通过使用连续稀释和校准方案测定片剂配方中的咖啡因来证明。
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引用次数: 5
The automation of solution phase synthetic chemistry using XP Zymate™ laboratory robotic systems 用XP Zymate实现溶液相合成化学的自动化™ 实验室机器人系统
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80003-2
David A. Rudge

The challenge of developing automated systems to undertake solution phase synthesis was embarked upon at Zeneca Pharmaceuticals in 1992. The objective of this project, using XP Zymate™ laboratory robots, has been realised with the establishment of a Research Department facility that has enabled research chemists to utilise the systems to generate compounds for test in relevant biological screens. The systems developed use the minimum of modification to the chemical method of reaction assembly, execution and isolation required of the products. This year will see the expansion of the Robotics facility from 3 to 7 systems. To date over 8000 novel individual compounds have been synthesised. Products have been purified where necessary, and over 30 different types of chemistry have been utilised. The work undertaken has covered the full scope of synthetic chemistry in the research process, incorporating library generation for high throughput screening, lead identification, and lead optimisation. To describe the work of the group an overview of the capabilities of the systems and the types of work undertaken, within the facility, is presented.

1992年,Zeneca Pharmaceuticals开始着手开发进行溶液相合成的自动化系统。这个项目的目标,使用XP Zymate™ 随着研究部设施的建立,实验室机器人已经实现,该设施使研究化学家能够利用该系统生成化合物,用于在相关生物筛选中进行测试。开发的系统对产品所需的反应组装、执行和隔离的化学方法进行了最低限度的修改。今年,机器人工厂将从3个系统扩展到7个系统。迄今为止,已经合成了8000多种新的单个化合物。产品在必要时进行了纯化,并使用了30多种不同类型的化学物质。所开展的工作涵盖了研究过程中的合成化学的全部范围,包括用于高通量筛选、铅鉴定和铅优化的文库生成。为了描述小组的工作,对系统的能力和在设施内进行的工作类型进行了概述。
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引用次数: 3
Method for extraction, extraction cartridge and automated extraction processing system 提取方法、提取筒和自动提取处理系统
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80011-1
Lessard Denis, Burrows John H
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引用次数: 0
Computerized specimen encoder 计算机样本编码器
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80013-5
Weissman Mark, Kamentsky Louis, Kamentsky Lee D
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引用次数: 0
Personal identification devices and access control systems 个人识别设备和出入控制系统
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80026-3
Davies John H.E.
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引用次数: 1
A system of network accessible self-guided training tools for clinical laboratories 一个网络可访问的临床实验室自我指导培训工具系统
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80002-0
Michael E. Sendek, M. Virji
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引用次数: 1
Computerized specimen encoder 计算机标本编码器
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80013-5
M. Weissman, L. Kamentsky, L. Kamentsky
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引用次数: 0
Password updating system to vary the password updating intervals according to access frequency 密码更新系统,根据访问频率改变密码更新间隔
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80025-1
Kadooka Etsuk
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引用次数: 0
Real-time scheduling and multitasking at the computer level, management of unplanned situations — a practical approach 实时调度和多任务处理在计算机层面,管理意外情况-一个实用的方法
Pub Date : 1997-12-01 DOI: 10.1016/S1381-141X(97)80004-4
M. Entzeroth
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引用次数: 2
期刊
Laboratory Automation & Information Management
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